"Kalchek": mirayiridzo kushandiswa, analogs, wongororo

Zvaunofanira kuziva usati kushandisa zvinodhaka ichi, sezvo "Kalchek"? Mirayiridzo kushandiswa vakati zvinodhaka zvaida kuverenga. Mariri uchawana zvairatidza uye contraindications kuti kushandisa zvinodhaka ichi, uyewo tione kana vane chero analogues nemishonga.

Chimiro rokugadzirira, akafanana uye chiputiriso

Unoziva chimiro umo unogona kutenga zvinodhaka "Kalchek"? Mirayiridzo dzokushandisa anotiudza kuti mushonga inowanikwa chete piritsi fomu. The Kuronga medicament anosanganisira basa chirungiso akadai amlodipine besylate (5, 2.5 uye 10 MG). Panyaya mamwe zvinokuvadza, ipapo vanosanganisira dibasic karusiyamu phosphate, chibage starch, yavaibvisa starch glycolate, ndokunatsawo talc, colloidal silica uye magnesium stearate.

Mahwendefa vari mhoni (10 hrs.), Izvo inoiswa bhokisi rakagadzirwa makadhibhokisi.

The pharmacological ehupfumi ane zano wezvokurapa

Sei mishonga "Kalchek"? Mirayiridzo Dzokushandisa rinoti kuti mushonga uri kusarudza karusiyamu mugero blocker pamusoro 2nd kirasi. Ane antianginal, antihypertensive, vasodilating, uye antispasmodic migumisiro. Somushonga zvinhu zvaisanganisira ari Zvinoumba mumiriri ichi, anokwanisa ichivharira aibuda karusiyamu ions kupinda vascular mvere tsandanyama masero.

Anti-vane chirwere cheBP ehupfumi zvinodhaka nokuda kwayo zvakananga chinozorodza nomugumisiro vascular wakatsetseka tsandanyama. Panyaya Anti-anginal Chaizvoizvo, medicament mu mubvunzo unogona kuwedzera arterioles (peripheral). Zvadaro, izvi zvinotungamirira vasanyanye peripheral vascular nemishonga, izvo zvinozoita kunotungamirira kune vasanyanye myocardial kudiwa O ₂ (okisijeni).

Zvisinei, zvinofanira kucherechedzwa kuti dzimwe nguva zvinoitwa ichi chinoreva nerubatsiro okisijeni, nekusiyana, vakawedzera. Izvi imhaka rokuwedzera coronary arteries (semuenzaniso, vasospastic angina).

Zvinofanira kucherechedzwa kuti nehwendefa "Kalchek" hapana nemigumisiro pamusoro lipid Zvinoumba ropa. Ivo nhaka antithrombotic uye antiatherosclerotic basa, kuwedzera filtration mwero (glomerular), uye vanewo safarira natriuretic kushanda.

In chirwere cheshuga nephropathy zvinodhaka haakwanisi kuwedzera microalbuminuria.

The pharmacokinetic ehupfumi zvinodhaka

Apo Absorção de Água zvinodhaka "Kalchek"? Nyanzvi Guest vanoti Absorção de Água zvinodhaka rinobva zvomudumbu turakiti (anenge 90%). pfungwa dzake mukurusa ropa mushure maawa 7-12. The bioavailability zvinodhaka riri pamusoro 63-65%.

The rinoita chinodhaka fuma chinopinda ropa-uropi chipingamupinyi uye yabudiswa pamwe mukaka. Amlodipine biotransformed ari chiropa (vakaneta metabolites vari akaumba).

Mugore kuchinja goho kuti asingasviki 10% of Pfungwa. Panyaya vakaneta metabolites, vari kuratidzwa mari 60% muna weti, uye vanenge 20-25% kubudikidza intestinal uye pamwe bile.

zvairatidza

In chii zvirwere murwere mapiritsi "Kalchek" unogona kupiwa? Mirayiridzo kushandiswa (akafanana mudziyo pasi apa) rinopa mashoko anotevera zvairatidza:

• chetevere angina;
• kusagadzikana angina;
• Chirwere cheBP (kushandiswa senzira monotherapy kana akabatana kurapa pamwe ACE FIs, thiazide diuretics, Beta kana Alpha blockers);
• angina angiospastic (kana inonzi Prinzmetal angina).

Contraindications

In pamberi upi ezvinhu omurwere havafaniri ushandiswe mapiritsi "Kalchek"? Mirayiridzo yokushandisa rine zvinotevera contraindications:

• arterial hypotension;
• Hypersensitivity kune huru vanoshingaira fuma mishonga.

Zvinofanira kucherechedzwa kuti mushonga haagoni kushandiswa varwere vane hypersensitivity kuti dihydropyridine nomukaka.

Drug "Kalchek": mirayiridzo kushandiswa

Mahwendefa "Kalchek" angina uye BP vari kutarisirwa nenzira chipimo chemushonga 5 MG pazuva. Kana zvakakodzera, unogona ngazviwedzerwe 10 MG.

Varwere chirwere sezvo dilated cardiomyopathy, kurapwa ndiye anosarudza pamwe dosages pamusoro 2,5 MG pazuva. Kana mushonga wacho zvakanaka akashivirira, zvinokwanisika kuti zvishoma nezvishoma kuwedzera dose (isingadariki 10 MG pazuva).

In kushanda mahwendefa sorutivi mubatanidzwa mishonga pamwe Beta-blockers, thiazide diuretics kana ACE FIs kuchinja zviri dosing zvaiitwa kunodiwa.

Zviratidzo ovhadhozi uye kurapwa kwacho

Ndezvipi zviratidzo ovhadhozi kuitika kana isiri dose mishonga "Kalchek"? Analogues mushonga pachayo anogona kukonzera raidudzwa hypotension. Sezvo kurapwa murwere inofanira kupiwa chinjikira chinzvimbo, uye zvishoma kusimudza makumbo ake. Uyezve, tinofanira kutsigira basa mwoyo uye ropa midziyo, vachiongorora zviratidzo zviri pulmonary kushanda hurongwa, kudzora diuresis uye Nyorera mumwe zvisingaoneke.

Kudzorera vascular matauriro murwere anopiwa vasoconstrictor zvinodhaka. Kubvisa migumisiro calcium mugero blockade, murwere chinotarisirwa (i.v.) karusiyamu gluconate.

zvinodhaka kwavatori

Mawa mapiritsi "Kalchek" uye "Warfarin" chinodhaka haakonzeri zvinokosha kuchinja prothrombin nguva utano vamiririri akasimba pabonde.

Kana ukashandisa vose vaiona medicament uye mishonga "Digoxin" Kwakanga kusina kuchinja muropa wevasungwa neyokupedzisira, uye ayo renal Clearance.

Mawa kwokubatsira zvinodhaka "Kalchek" uye "Cimetidine" asina zvainoita pharmacokinetic ehupfumi kuti amlodipine.

Pregnancy uye lactation

Kana zvichibvira panguva lactation uye gestation mufambiro kugamuchira "Kalchek" Mahwendefa? Mirayiridzo yokushandisa, vanachiremba chaivo kukuzivisai kuti efficacy uye kuchengeteka zvinodhaka ichi pamuviri uye kuyamwisa mwana wako hauna kuisa.

Side Migumisiro zvinodhaka

Chii nemishonga inogona kukonzera mapiritsi "Kalchek"? Mirayiridzo vachishandisa nzira iyi inosimbisa chokwadi kuti kugadzwa kwake kunogona kukonzera chinja zvisingadiwi mumuviri. kunyanya zvakajairika pakati pavo ndedzinotevera:

• Midziyo uye mwoyo, kupfupika mweya, palpitations, uye inopisa flushes.
• Tsinga (peripheral uye nechepakati): kuchinja, dzungu, tsandanyama chinyamunhari chinorwadza, nomusoro, madzerere, hope, asthenia, kurukutika, paresthesia uye myalgia.
• Zvomudumbu turakiti: abdominal marwadzo, dyspepsia, cholestatic jaundice, kuda kurutsa, kuwedzera transaminases (chiropa).
• Skin: erythema multiforme, pruritus, mapundu.
• Other: gingival hyperplasia isiri yekenza, gynecomastia, vakawedzera kakawanda weti, kusabetsera uye kuzvimba.

Mirayiridzo Special nokuti kugamuchira zvinodhaka

Imhandoi nuances vaiona mushonga unofanira kuziva usati uchengete aine mahwendefa "Kalchek"? Nyanzvi Guest vanoti mishonga iyi inofanira kushandiswa nokungwaririra zvakanyanyisa kune vanhu vane havachanyatsogoni chiropa basa, uyewo mwoyo kukundikana (chirwere) uye kutsemuka stenosis.

Mawa negashiro mishonga "Kalchek" nevasiri steroidal vamiririri, nitrates, mishonga uye hypoglycemic mishonga (dzinogamuchidzanwa) zvinokwanisika.

Zvakaitika kunotoda kushandiswa kwezvinodhaka muvana vaduku chinoshayikwa.

Mahwendefa "Kalchek" hazvina zvazvinoita murwere anogona kutyaira motokari.

Terms uye zvemupiro kuchengetera mushonga

Kugadzirira "Kalchek" (5, 10 uye 2,5 MG) inofanira kuchengetwa nenzira inotonhorera, yakaoma, nzvimbo yerima pasigasvikirwi vana vaduku. The pasherefu upenyu mahwendefa ndiyo 2 years.

Reviews of somushonga chigadzirwa, uye mari analogues ayo

Chii chinogona kutsiva chombo akadai "Kalchek"? Analogs zvinodhaka izvi zvinowanikwa zvinenge zvose drugstores. Pakati rakajairika yomuchipatara zvinosanganisira zvinotevera medicaments: "Agen", "Tenoks" "adipic", "Stamlo", "Akridipin", "Omelar Cardio", "Amlo", "normodipin" "Amlodipine" "Norvasc" "Amlovas", "Amlorus", "Norvadin", "Amlodigamma", "Cordy VaK", "Amlodhi", "Korvadil", "Amlodifarm", "Karmagip", "Amlokard-Sanovel", "cardilopin", "Amlong" "Vero Amlodipine", "Amlotop", "Amlonorm".

Chii Mari mari? Avhareji mutengo zvinodhaka riri 175-190 rubles Russian (5 MG, mapiritsi 30).

With Panyaya zvakataurwa kuvarwere, ndivo akanaka vakawanda. Maererano avo nokusingaperi vakashandisa mushonga, izvozvo zvinobudirira anorwa navo angina uye BP. Zvinofanira kucherechedzwa kuti vakawanda varwere vanofara uye kuti chinodhaka ichi tichishandisa zvakanaka akashivirira navo. Kunyange zvazvo mune zvimwe zviitiko piritsi "Kalchek" vachiri kukonzera marwadzo akadai musoro, abdominal marwadzo, dzungu, kuda kurutsa uye neutachiona paganda.