"Metformin" (Mahwendefa): kudzidziswa manual, ongororo, akafanana, kushandiswa uye kukuvadza muviri

Chirwere cheshuga - imwe pfungwa yakajairika nezvirwere munyika. Gore negore nhamba Muzviitiko kaviri. Chirwere cheshuga mellitus ikabuda metabolic kusagadzikana mhando mbiri - kana muviri pachavo jekiseni kukwana (wokutanga mhando) uye kana vavhunduke mugumisiro jekiseni iri rinenge (rechipiri mhando). Type II chirwere cheshuga kunoitika muna 80-90 muzana zvose nyaya uye kazhinji kuoma nezvinhu zvakadaro zvisingafadzi zvinhu zvakadai kufutisa. In kurapwa kwezvirwere yakanakisisa Ndakaratidza zvinodhaka "Metformin" - pamahwendefa, iyo nemhaka ehupfumi awo mukurumbira chaizvo pakati pevaya vanoda uremu, asi haana kurwara cheshuga.

Chii chinonzi "Metformin"

"Metformin" uye analogues ayo - hypoglycemic mishonga nachiremba pakurapa chirwere cheshuga - zvikurukuru chechipiri mhando, asi mune zvimwe zviitiko nzira wokurera uye wokutanga mhando. Sezvo inception kwayo muna 1957, "metformin" kunoramba aitungamirira chinodhaka pakurapa chirwere cheshuga, kunyanya kana matambudziko akadai kufutisa. Jekiseni kunoita mafuta kuchengetwa, uye "metformin", kuderedza jekiseni yomuropa mumuviri uye anobatsira kubvisa nayo. Zviri nokuda chiito ichi, vazhinji kushandiswa senzira slimming "Metformin" piritsi.

Zvinoumba "Metformin," Mahwendefa

Zvinoumba mahwendefa rinosanganisira rinoita chirungiso metformin hydrochloride, yakaitwa kubva dzinongoitika zvinhu kuti vakawana kubva Lilac French uye mbudzi Rue. Excipients gadziriro - talc, chibage starch, magnesium stearate, titanium dioxide, uye povidone K90, crospovidone uye macrogol 6000.

Zvairatidza kuti Munopinda "Metformin"

Zvikurukuru "metformin" - mapiritsi kuti nezvaro cheshuga mellitus mhando 2 pasina katsika ketoacidosis (kuvhiringidza carbohydrate muviri nokuda kushayikwa jekiseni). Kunyanya kana mushonga anoratidza murwere kufutisa apo zvokudya marapirwo kwakanga isashande. Uyewo kuti kufutisa unogona kupiwa akabatana jekiseni.

With chirwere ichi, zvakadai sechirwere cheshuga, "Metformin" Hwendefa raitongwa sechinhu yoga kugadzirira kana akabatana antidiabetic vamiririri mamwe mapoka, kana tiri kutaura pamusoro rechipiri mhando. In wokutanga mhando kwayo chinotarisirwa kuva kwokunwa inokosha jekiseni.

kuongorora kwesayenzi Recent dzakaratidza kuti "metformin" rinoshandiswawo zvinobudirira pakurapa oncology-ukama chirwere cheshuga.

Kuitwa metformin

Metformin kunowedzera aikanganiswa masero kuti jekiseni. Ropa shuga pamwero ipfupi uye remafuta akawandisa. The unorapa kwegadziriro kwacho zvaanopa simba mafuta oxidation, usarega digestible makabhohaidhiretsi uye nokudaro kuita mafuta kuunganidza mumuviri.

Jekiseni zvinokonzera mafuta deposition kwacho, kunyanya mune matambudziko munzvimbo (zvikurukuru, mudumbu). Saka, zvokudya akawanda dzinobva ndechokuti bvisa kubva kudya zvokudya zvinowedzera ropa shuga yomuropa. Metformin uyewo anovanza nzara kunokonzerwa jekiseni.

Release chimiro uye chipimo chemushonga

"Metformin" - zvemapuranga pamahwendefa, 500, 850, uye 1000 MG, mu mhoni packs it ayo wakabudiswa zvidimbu 10, muri chena. Tanga kurapwa pamwe 500-1000 MG pazuva, kuti mahwendefa 1-2. Dose, zvichienderana padanho shuga muropa, inogona kuwedzera zvishoma nezvishoma pashure pamazuva 10-15 yokurapa wokutanga, asi havafaniri kutora MG anopfuura 3,000 pazuva. Maintenance dose - 1000-2000 MG (3-4 mahwendefa). "Metformin" mirayiridzo uyewo haana ichikurudzirwa kutora chipimo chemushonga anopfuura 1000 MG pazuva vakwegura.

Mahwendefa dzinoitwa zvachose munguva kana pashure kudya, kushambidzwa pasi nemvura. Dzimwe nguva mubvunzo unomuka kana zvichibvira kugovera pahwendefa ( "Metformin") hafu. Kana totaura kuti dose 500 MG, kuita chinhu kuti haisi noitika, sezvo rezasi dose haapi zvinozoita, uyezve, haisi yakarumbidza kuputsa ganda, kana vakafukidza piritsi. Kana zviri chete zvakaoma kumedza nokuda size, zvino rinogona muzvikamu zviviri uye kutora chikamu - asi chimwe chete pashure perimwe.

Sezvo "Metformin" anogona kupa divi migumisiro iri nemudumbu, nezuva dose anofanira kutorwa kwete kamwechete, asi muna zviviri kana zvitatu mishonga masikati, zviri nani apo vachidya. Kana uri kusangana zvakakomba metabolic zvinetso, asi dose anofanira kuderedzwa.

Kana, kana uine kutora mamwe mishonga munguva imwe chete, kana kutora "Metformin" (Mahwendefa), kudzidziswa Chinyorwa rine ruzivo pamusoro mishonga inogona pamwe "metformin", uye izvo haagoni. Uyewo, iva nechokwadi kuti bvunza chiremba wako pamusoro kudyidzana pakati zvakasiyana yomuchipatara ne "metformin".

analogs

Kazhinji, varwere vanofarira analogues zvinodhaka - zvikuru isingadhuri kana hubudirire, kusanganisira kana vachida mapiritsi zveshuga. "Metformin" ane analogues zhinji tinazvo akafanana navo musimboti chiito. Chokutanga ndechokuti "Glucophage" uye "Siofor", mumwe zvikuru nevanhu inotsiva, "metformin" uyewo zvimwe mari kuti zvakafanana vanoshingaira chirungiso, saka kuti saizvozvo kukanganisa muviri uye zvakafanana zvairatidza kuti womuchato, izvo "Metformin" piritsi. Reviews ose analogues zvinogona kuverengwa paIndaneti, unogona enzanisa murayiro kushandiswa, kuti vafunga uye sarudza zvakanaka zvinodhaka.

Analogs "Metformin" ndiwo:

• "Bagomet";
• "Hexane";
• "Glucones";
• "Gliminfor";
• "Metospanin";
• "Metfogamma" (500, 850, 1000);
• "Nova Met";
• "NovoFormin";
• "Sofamet";
• "Formetin" nevamwe.
• "Siofor" (500, 850, 1000) - zvinodhaka German, akatorwa nemuromo ane hypoglycemic nomugumisiro, imwe yokutsiva wakanakisisa nokuda jekiseni jekiseni.

Kana "Glucophage", mamwe dzinodhura ndiye "Metformin" asi kana ake kubvuma varwere 50 muzana kashoma kuti vanotambura zvinetso zviri gastrointestinal hurongwa. "Glucophage" chinoratidza mhando chirwere cheshuga wechipiri, akashandisa zvose oga uye akabatana nevamwe zvinodhaka. Kushanduka "Glyukofazh Long" zvava nguva ukoshi.

Zvikurukuru, zvinodhaka zvose izvi zvakafanana sei nhengo nheyo, nekuti vane imwe kushingaira fuma iri paro.

Pane Mishonga zvokuwedzera kuti anobatsira tikarega ropa shuga yomuropa:

• "Vidzhar" (uyewo lowers remafuta akawandisa, zvaanopa simba dziviriro yezvirwere mumuviri kunokutadzisa pave nemavhairasi uye zvirwere zvinokonzerwa noutachiona);
• "Spirulina" (anobatsira mune kusagadzikana metabolic urongwa, mukurwisa yokufutisa);
• "Glyukoberri" (kunoderedza ngozi yematambudziko kwechirwere cheshuga), uye vamwe.

Zvisinei, Mishonga zvokuwedzera havafaniri kunzi womutariri zvakakwana chinodhaka, vanogona kushandiswa senzira kwokunwa inokosha kurapwa. Kuwedzera kugamuchira Bud unofanira bvunza chiremba wako nezvazvo.

"Metformin" iri cheshuga

"Metformin" - mumwe yakanakisisa Anti-shuga nevamiririri nhasi. Zviri inoshanda chaizvo pakurapa chirwere cheshuga mhando, anogona kupiwa akabatana jekiseni, uye dose anosarudzwa zvichienderana uwandu shuga muropa.

Pakurapa chirwere cheshuga, izvozvo kuchititadzisa gluconeogenesis, pasina kukanganisa nenhanho jekiseni muropa. It kunowedzerawo kweropa iri chiropa, vachibvumira shuga nokukurumidza dzikwanise glycogen.

Kana kurapa mhando II chirwere cheshuga , "metformin" anogona vakatarirwa upenyu. Kana chinotarisirwa akabatana nevamwe antidiabetic vamiririri, zvinokosha kuongorora padanho shuga kuti vadzivise yomuropa. Pamusangano yoga negashiro zvinodhaka asingadi kuva yomuropa.

Uyezve, rinoshandiswa pakurapa varwere vanenge kufutisa, chinowanzoguma cheshuga sezvo anovanza kudya uye akazoita Absorção de Água kuti shuga kubva zvokudya zvomudumbu turakiti.

In wokutanga mhando zvinodhaka rinoshandiswa senzira kwokunwa jekiseni nezvimwe chirwere cheshuga nevasori, oga rinogona kutorwa chete cheshuga mhando 2. Pakutanga kurapwa, "metformin" negashiro dzimwe hypoglycemic yomuchipatara zvinofanira kumiswa.

"Metformin" kurapa anewo nomugumisiro pamberi kunobatsira vari metabolic chirwere uye lipid muviri zvirwere.

Metabolic chirwere - huri muviri, umo nhamba akabatana zvinoita: vasingadzoreki carbohydrate muviri, murwere anotambura neBP, kufutisa, etc. The chirwere achabatsirwa mikana yokuita zvemwoyo chirwere .. Hwaro ichi ndiko insulin irambe, izvo, maererano kuongorora kuchangobva kuitwa, hunonyatsobatana chirwere cheshuga uye vascular chirwere.

Panyaya lipid muviri, somugumisiro wacho kuongorora zvakanga vakawana kuti padanho triglyceride, zvachose remafuta akawandisa uye LDL remafuta akawandisa ipfupi kana ukawana mapiritsi zveshuga "Metformin". Reviews masayendisiti pamusoro zvinodhaka ichi dzinewo mashoko kubudirira kwayo kudzivisa chirwere cheshuga rechipiri mhando pakuparwa kutyora carbohydrate shiviriro.

"Metformin" slimming

The dzinokosha ehupfumi zvinodhaka nekusimba uremu pavarwere chirwere cheshuga zvakakonzera chokwadi chokuti "Metformin" akanga akakurumbira pakati pevaya vanoda kuderedza uremu.

Pasinei nokuti mushonga chaizvoizvo unotangazve pezvakaitwa kuti anobatsira kupisa zvakawandisa mafuta uye regai kupa kuumba itsva mafuta deposits, yoashandisa vanhu pasina chirwere cheshuga, nokungwarira, uye zvakakosha kufunga panguva wandei ezvinhu.

Chokutanga tinofanira kuyeuka kuti mushonga pacharo haachemeri mafuta, asi chete zvinobatsira kupedza kwayo pachisara zvaitika kuti ichi chiri pamwe kushingaira muviri uye rinokosha kudya. "Metformin" - mapiritsi havasi zvinoshamisa ehupfumi, asi chete chimwezve chokushandisa. Kunyange pakati vanachiremba hapana chete maonero munhu anogona kutora "Metformin" piritsi: zvakanaka uye kukuvadza nemuviri zvinodhaka ichi zvinofanira kuongororwa nomumwe neimwe nyaya. Vamwe vanachiremba varayire ndezvenguva murwere kuti nokukurumidza uremu, vamwewo kunokuvadza chaizvo kune muviri. Naizvozvo, kana kurasikirwa uremu achibatsirwa "Metformin" rokutanga kuongororwa uye zano nyanzvi chinodiwa kusarudza zvakanaka.

Next, unofanira kufungawo wandei contraindications. Somuenzaniso, kana uine chirwere cheshuga mhando rokutanga kana kuti rechipiri pasina jekiseni, achiita "metformin" uye kugadzirisa zvinetso kurasikirwa uremu kunogona chete kushandisa endocrinologist.

Chero zvazvingava haagoni kutora mushonga mu itsvo, mwoyo, zvemapapu kukundikana, chiropa chirwere, kupererwa neropa.

The mushonga haagoni kushandiswa kana muviri simba - pashure pokuvhiyiwa, kunotevera, chirwere chakakomba payo, inofanira kudziviswa panguva chakasimba zvinotapukira.

Zvinonzi rambidzwa kutora "Metformin" kana iwe kuomerera yakaderera mafuta zvokudya.

Huru pezvakaitwa kuti kuitika mumuviri necheseri, "metformin" kurapa uye zvinobatsira uremu, ndiko:

• nokukurumidza mafuta oxidation;
• rutapudzo ari kuitwa zviri makabhohaidhiretsi;
• nani shuga uptake kubudikidza tsandanyama tishu;
• dzikira kunzwa nzara, zvichizoita akaderedza muviri uremu.

Kusingadzoreki uremu pamwe kwezvinodhaka izvi kazhinji marwadzo, kunyanya kana iwe wakatora hombe dose pane anobvumirwa maererano nemirayiridzo. Kuwedzera kune chinokosha nezvinetso nemudumbu, unogona kuva simba, lethargic, usimbe, anogona kuva lactic acidosis kana zvimwe chirwere chakakomba.

Uyewo, kana kugamuchira "Metformin" kwokutevera zvokudya. Kana dziripowo zvihwitsi, Pasta, mbatatisi, zvinwiwa. Meals vanofanira kugara, haugoni nenzara, asi muviri ukoshi haafaniri kupfuudza 2500 kcal pazuva. Panguva iyi, unofanira kunwa zvikuru sezvo mvura inobvira senguva yakachena.

Pasinei chokwadi chokuti "Metformin" hakubvisi kudiwa kuita rinorema kurovedza, hazvirevi kuti chero basa chaiko zvinogona kudziviswa. Morning zviitwa, vanoshingaira siyana varaidzo, neiznuryayuschaya muviri pamwe mishonga inogona kubatsira chaizvo nokukurumidza kubvisa zvakawandisa mafuta. Hazvina zvakafanira kutarisira kuti "Metformin" achaita pasina okuwedzera ushande nesimba kuita zvose iwe!

Abatanidzwe mune zvinodhaka uye kuushandisa panheyo "zvikuru - zviri nani" haasi: Regai kusapfuudza dose, kana ukatora "Metformin" (Mahwendefa). Mirayiridzo dzokushandisa anopa nhungamiro yakajeka pamusoro kunonyanyisa dose mari vasiri kutevedzera zvinogona yekudyidzana kukuvadza muviri. Uyezve, mushonga uyu unogona kutorwa asisiri kupfuura mitatu, ipapo iwe uchida kutora kuregawo.

Zvino unogona kuwana zvakawanda wongororo vaya vakatora "Metformin" mapiritsi. Reviews zvakasiyana: mumwe ndikabvisa zvakawandisa mafuta nokukurumidza uye zvachose, mumwe chaitadzisa tsika dzakaipa kana nemishonga. Asi vose, tinogona kugumisa kuti vaya "Metformin" akabatsira kutora pasi yachiremba cherechedzo, pashure pokuongororwa, chiitwa kudya kwakakodzera uye muviri haina kuchengetwa.

Contraindications kuti "Metformin"

Asati atanga kurapwa, "metformin", pasinei uine chirwere cheshuga kana kana uchida uremu, unofanira tinyatsoziva anoyevedza ndandanda contraindications uye chiremba.

Kuwanda contraindications vari renal, cardiac, pulmonary insufficiency, yakanyanya zvokurwara chiropa uye biliary turakiti; chisingaperi zvirwere kufema zvomukati. The mushonga haafaniri kubatwa post-zvinorwadza uye post-kushanda nguva, uyewo post-myocardial infarction munguva vapore nguva. Rubvumo "Metformin" iri contraindicated mu noutachiona uye anogumbura pezvakaitwa uye exacerbation upi chirwere zvirwere, yakanyanya siyana kupererwa neropa.

The mushonga hakubvumidzwi panguva yepamuviri uye lactation. Kana kuronga pamuviri kana kutanga kwake pamusoro yaitwa mabiko "Metformin" zvinodhaka kunodiwa mapfumo uye anozodzidza kubaya jekiseni. Achiyamwa, kana uchida kuti kurapa nayo, "metformin", unofanira kudzima, nekuti hapana mashoko ari kubata mushonga pachipfuva mukaka, asi kunyange chiduku chakapatsanurwa zvinodhaka kuti anenge apinda mukaka ngozi mwana, sezvo iri nhamba contraindications - makore 18 makore. "Metformin" hakuratidzwi vana nevechidiki pasi makore 18.

Uyewo, "Metformin" harifaniri kubatwa kana udhakwa uye rikwanise doro chepfu. Kazhinji, zvinokosha kuramba kutora doro uye panyaya iyi tubhokisi mishonga, kana ukatora "Metformin". Chokwadi chokuti mubatanidzwa metformin uye panyaya iyi kunyange mishonga diki, kunomutsa kufambira kukura laktotsitoza, kusvikira pakufa.

Zviri ngozi kutora "Metformin" panguva chenguva yakaderera-mafuta uye "nzara" zvokudya.

It haigoni kubatwa nevanhu makore 60 kana vari mubasa rinorema remaoko, kudzivisa pave lactic acidosis.

Panguva kurapwa, varwere vanofanira kuongorora renal basa, kuongorora padanho lactate muna plasma, serum creatinine.

Side Migumisiro zvinodhaka

"Metformin" chinokurwadzai dzinoverengeka nemishonga. Naizvozvo, kana kurapa zvakakodzera kuti nokungwarira kuongorora mamiriro nhengo uye chitarisiko zvichemo kubvunza chiremba pakarepo, kunyanya kana uri kutora mushonga haungopiwi nachiremba uye pachako.

Wokutanga mushonga kunokonzera kukundikana pamusoro chikamu nemudumbu. Muchiitiko chino, zvinobvira zvisingafadzi zviratidzo zvakadai:

• svoto;
• kurutsa;
• Kuramba manyoka;
• flatulence;
• kurasikirwa havi;
• chitarisiko esimbi manakiro mumuromo;
• pakuonekwa marwadzo mudumbu.

Uyewo, murwere anogona chokunyunyuta pamusoro kufema kukundikana, tachycardia, mapundu uye desquamation ganda, kazhinji kuvaviwa.

A zvisingawanzoitiki asi ngozi divi chaizvoizvo - lactic acidosis. Kana lactic acidosis, lactic asidhi anopinda muropa, zviratidzo zvokutanga - utera, hope, kurukutika, kuwedzera kuda kurutsa, kurutsa.

Apo chirwere kwokubatsira mushonga arege chiropa dysfunction.

Kana ukaona pane imwe kuratidzwa izvi, unofanira pakarepo bvunza chiremba achimuudza kuti uri kutora, "Metformin" piritsi. Kubatsira uye anokuvadza muviri mune iyi angava gogonera, zvichida haufaniri kutora zvinodhaka uye vanofanira kuwana zvimwe zvaungaita kuti kurapwa kana uremu.

pfupiso

"Metformin" - zvikuru apo hwendefa mhando 2 chirwere cheshuga. "Metformin" kunobatsirawo kuderedza uremu, asi zvinokosha kuyeuka kuti zvinodhaka izvi haisi mushonga, hazvina kutsiva low-carb zvokudya uye muviri. Zvipatara "metformin" kunofanira kubatana kudzora ropa shuga yomuropa uye kudzivisa miitiro inokuvadza, kusanganisira zvokudya. Kana uchida kurasikirwa uremu nacho, usakanda mapfumo pasi yokurovedza muviri, kudya kunovaka, uye musakanganwa kuti pakutanga ndiwo mishonga chakakomba, Mwari akaronga kuti kubata cheshuga, saka zvakakodzera kutora renyevero uye chete mushure mekubvunza chiremba wako.