Ondansetron: zvakafanana, mirairo yekushandiswa, mitengo

Pane zvirwere zvakawanda zvinoda kubatwa kwe antiemetics, iyo inogona kubvisa zviratidzo zvekutsvaira uye kusuruvara. Izvi zvinonyanya kukosha mumushure-opera nguva, apo muviri unobva kune anesthesia. Uyezve zvakakosha kupa mishonga iyi mukugadzirwa kwechemotherapy uye remapiritsi emishonga. Mishonga yakadaro yakadaro inosanganisira Ondansetron. Analogues (mazano "Emetron", "Latran", "Zofran") zvakare kwenguva pfupi ichabvisa zviratidzo zvekudhakwa nekurutsa.

Action medication «Ondansetron»

Mishonga iyi ndeyeboka re antiemetics. Kubudirira uye kwenguva pfupi inobvisa kusuruvara nekurutsa kwakavapo mushure mekushanda kwenguva, shure kwechemotherapy uye remishonga inonzi radiation. Mhedziso yemishonga ndeyokuti inokwanisa kudzivisa kusarudza serotonin 5-HT3 receptors. Somugumisiro, iyo emetic reflexes inopera.

Mushure mekupedza, mishonga inokurumidza kupinda mukati mudumbu. Inenge 100% inobatanidza neropa reprotein. Chiropa chinokonzerwa nepamusoro metabolism. Mumaawa mana, chirwere ichi chinosvika pakucherechedza kwaro kupera. Nausea nekurutsika kunoitika nekuda kweOndansetron mishonga. Analogues uye zvinotsiva zvechirwere zvine chimiro chakafanana uye chinogona kushandura zvachose chakasikwa.

Zviratidzo uye zvinopesana

Zviratidzo zvikuru ndezvekurapa nekudzivirira kusuruvara nekurutsa mushure memakemikrasi uye remishonga inonzi radiation, uyewo munguva inotevera. Pane zvakasiyana-siyana zvinopesana:

• Iwe haugoni kutora mushonga muhafu yekutanga yekuzvitakura;
• Nekuwedzera kwekunzwisisa kune zvikamu;
• Nokuchenjerera kuisa kune varwere vane kidyo uye chiropa chechirwere.

Kushanda

Mushonga unobatwa pane mumwe munhu. Zuva rezuva nezuva rinoenderana nekuoma kwezviratidzo, pamwe nekudhakwa kwemuviri panguva yekufamba kwemaawa uye chemotherapy. Munguva iyo mushure mokuvhiyiwa, mushonga unorayirwa kazhinji pazuva kusvikira zviratidzo zvekutsvaira nekutuka zvinyangarika zvachose. Chiremba chete anokwanisa kupa Ondansetron. Mirayiridzo kumudzvinyiriri iri mukati memudziyo wezvinodhaka.

Hazvibvumirwi kushandisa nzira yekubatanidza ne inducers ye cytochrome enzyme system, iyo inogona kutungamirira kubvumo uye kuderera kwekuregerera kwezvinhu zvikuru (ondansetron).

Iwe haugoni kupa mishonga iyi mumutambo wekutanga wekuita pamuviri. Kana iwe uchida kushandisa mushonga munguva yeactation, iwe unoda kurega kudya. Uyezve, varwere mushure mekuvhiyiwa pamimba vanofanira kunyatsotora mishonga kuitira kuti varege kuvanza zviratidzo zvekurwadziwa kwepachivi. Nehutachiona hwechiropa, usapfuure muzana we 8 mg weOndansetron.

Nhaurirano nematengo, zviratidzo uye zvinopesana - zvose izvi ruzivo runofanira kujekeswa vasati vatanga kurapwa.

Mutengo wechirwere ndeye zana makumi maviri nemabhesi pamapato.

Matambudziko:

• Headaches;
• Kusvika kuvhiringidzika kunoonekwa uye chizivo;
• Kuchengetedza kwezvinetso;
• Tachycardia;
• Allergic reactions;
• Kufunga kwehuni mumusoro.

Latran

Rinotsanangura antiemetics. Kubudirira kubvisa zviratidzo zvekushungurudza uye kushambidzika munguva inotevera, panguva yekemotherapy uye remishonga inonzi radiation. Mushonga unokwanisa kudzivisa kusarudza serotonin 5-HT3 receptors. Kana ikashandiswa, mushonga wacho unobatwa mudumbu munguva pfupi. Inenge 100% inobatanidza neropa reprotein. Inodarika metabolism muropa ne hydroxylation.

Kunyanya kuwanika kwechirwere ichi kunowanikwa mukati maawa mana kubva panguva yekutora muzana wekutanga. Ichi chiito kune pamuviri mushonga "Latran". Chimwe chinhu chakafanana ndiOndansetron. Analogues, zvinyorwa uye ma generics zvinogona kushandiswa chete mushure mekutaurirana nechiremba anouya.

Mutengo wemishonga iyi ndeye 180-200 rubles mune mamwe ma pharmacy akasiyana-siyana.

Application Features

Kudzivirira uye kurapa kurutsira uye kushungurudzika munguva yekushanda, uyewo shure kwekemotherapy uye remishonga inonzi radiation. Iwe haugoni kupa mishonga iyi mumutambo wekutanga wekuita pamuviri uye nekuwedzera kwekunzwa kwechirwere. Uyewo, iyo mumiriri haisi kurongerwa kurwara kwechiropa uye neitsvo. Mishonga haigone kushandiswa pakudya chepfu kana doro.

Chirwere chacho chinogadzirirwa mumwe nomumwe uye kufungisisa kusimba kwechirwere chacho. Chikoro chinoenderana nezviratidzo uye kuvapo kwekudhakwa kwemuviri. Haikwanise kutorwa pamwechete nemapiritsi ayo ari inhibitors e cytochrome isoenzyme system. Pasina kubvunzurudza nachiremba, hazvikurudzirwi kutora mushonga weLatran, pamwe neOndansetron medical solution (injection solution). Iyo murayiridzo inotsanangura kuti ungashandisa sei mushonga wechinangwa chekuziva chete.

Zvikanganiso

Muzviitiko zvakawanda, mushonga wacho unobvumirwa zvakanaka. Kazhinji kazhinji, zviratidzo zvinotevera zvinogona kuitika:

• Kuona kusina kunaka uye chizivo chechirongwa chisingaperi;
• Headache;
• Bradycardia;
• Kukosha kunoderedza kudzvinyirira;
• Constipation;
• Mucheche kurwadziwa;
• Kunzwa kwekupisa.

Usatungamira mhinduro kana mahwendefa panguva yenguva yekurera uye yekuyamwisa. Uyewo, chiyeuchidzo chinofanira kupiwa mushure mekuvhiyiwa pa peritoneum, kuitira kuti usapotsa zviratidzo zvekurwadziwa kwepachivi. Miyero yakafanana inofanira kuonekwa kana ichibata naOndansetron. Mirayiridzo yekushandiswa, zvakafananidzwa, kuenzanisa kwakakwana - zvose ruzivo runofanira kuongororwa musati watanga tachirapa, uye kana uine mibvunzo, taura neunyanzvi kune mazano.

Zofran

Chigadzirwa chacho ndecheboka remishonga antiemetic. Kubudirira kubvisa zviratidzo zvekurutsa uye kushungurudzika panguva yechemotherapy, radiotherapy uye mushure mekuvhiyiwa. Mushandi anosarudza zvinogona kudzivirira serotonin 5-HT3 receptors, iyo inoderedza zviratidzo zvekudhakwa. Inenge 100% inosanganiswa neropa reprotein. Maximum bioavailability inowanikwa maawa mana mushure mokutora mishonga. Chaizvoizvo, chinhu chakanyanya chemishonga yeZofran chinoshandiswa mumagetsi muchiropa. Kutanga kunofanira kuverengwa, uye kusati kwashandisa mushonga "Ondansetron", murayiridzo. Nhaurirano, sekutonga, haisi yakasiyana nekugadzirwa uye zviratidzo. Zvakakosha "Zofran" anenge mabhuru makumi matatu.

Zvinoshandiswa zvekushandiswa

Iyo inorayirwa kurapwa uye prophylaxis munguva yekuvhiyiwa uye chemo- uye radiation therapy. Iwe haugone kuitora muhafu yekutanga yekuzvitakura uye panguva yekuyamwisa. Uyewo haakurudzirwi ne hypersensitivity kumushonga. Mishonga haigone kushandiswa kurega kurutsa uye kubvisa zviratidzo zvekudhakwa panguva yehupfu.

Chirwere chacho chinogadziriswa chete nachiremba, uye zvichienderana nekuoma kwemamiriro ekurapa mushure mekunge chemotherapy uye post-operation nzira. Chirwere chacho chinotorwa kusvikira zviratidzo zvekudhakwa zvinyangarika zvachose. Hazvikurudzirwi kushandisa nzira yekubatana ne inhibitors ye isozyme isozyme system. Izvi zvinofanira kufungwa nezvazvo kana kurapa Ondansetron. Nhoroondo dzechirwere chinogona kunyatsogadzirisa chepakutanga uye kuchengetedza murwere kubva mukurutsira nekunyunyuta.

Matambudziko:

• Kutsiva uye kutadza kuona;
• Headache;
• Kuvharwa kana kubuda;
• Kupera kwemafupa eropa;
• Bradycardia;
• Pain mucheche.

Kana uine zviratidzo zvisingafadzi, unofanira kutsvaga kubatsirwa nachiremba. Nyanzvi inoderedza kuyerwa kana kugovera chimiro chekuita.

"Emetroni"

An antiemetic drug inodzivirira serotonin receptors uye ine chinhu chikuru.

Mushonga wacho uri mhando yehwendefa yemavara uye mararamiro. Mishonga iyi inorayirwa kuti ibvise kurutsa uye kushungurudza mushure mekuvhiyiwa uye mukushandiswa kwechemotherapy uye remishonga inonzi radiation. Nehutachiona kana hutachiona hwekutonga, kushanda uye kuderera kwekudhakwa kunoonekwa kwemaminitsi gumi. Izvozvo zvinokonzerwa nemhinduro yeOndansetron. Analogues akafanana zvakafanana mukugadzirwa.

Mutengo wemishonga mune mamwe ma pharmacy inopfuura 1200 rubles papepa.

Zviratidzo uye zvinopesana

Inorayirwa kubvisa kurutsa uye kusuruvara panguva yekushanda kwenguva uye panguva yekutengesa chemo- uye radiotherapy muvana nevakuru. Kuti abvise kudhakwa panguva yehupfu, mishonga haigone kushandiswa. Pane zvipupuriro zvakasiyana zvekugamuchira:

• Period of pregnancy;
• Lactation;
• Zera kusvika kumakore maviri;
• Hypersensitivity kune zvinoshanda zvinoshandiswa.

Chirwere ichi chinotarisirwa pamwero we 8 kusvika ku 32 mg pazuva. Nhamba yezuva nezuva inobva pakusimba kwekudhakwa uye kumunhu mumwe nomumwe maitiro ehupenyu. Nehanya, mushonga unorayirwa kune varwere vane chiropa uye chirwere chepfungwa. Uyewo "Emetroni" mumiririri akaderera mairi anoshandiswa mukukwegura.

Ongororo

Muzviitiko zvakawanda, mishonga ine mhinduro dzakanaka uye inobvumirwa zvakanaka nevarwere. Munguva pfupi inobvisa zviratidzo zvekudhakwa kwemuviri, izvo zvinoratidzwa mukurutsa nekunyunyuta. Mushonga hauiti kukuvadza muviri uye inogona kujowa kusvikira zviratidzo zvehupfu hunopera zvachose. Maererano nekuongororwa kwevarwere uye vanachiremba, zvinokonzera kuitika kune Ondansetron zvinogona kukura. Nhoroondo dzinogonawo kukanganisa mikoko uye kunyange anaphylactic shock. Nokudaro, muyero unongoratidzwa chete neyanyanzvi, uchifunga nezvehumwe humwe hutano hwemuviri wemurwere.

Mushonga hausi muropa uye unoburitswa nenzira yesarudzo uye mahwendefa, ayo akakodzera kuvarwere vane utsinye hupi hwehutano. Iyo inotsanangurwa zvinodhaka inogona kushandiswa kubva kune makore maviri. Iwe unogona kutenga mishonga mune chero mapeji. Vanachiremba vazhinji vanorayira zvakadai semishonga kuti vadzivise zviratidzo zvekudhakwa.

Kana pane chido chekupa mishonga panguva yekuyamwisa, zvino zviri nani kuramba urusi. Nyanzvi dzinocherechedza kuti izvo zvinoshandiswa zvinoshandiswa zvinopinda mumukaka uye zvinogona kukanganisa utano hwechechecheche. Uye, hongu, pamwe chete usati watora chero mushonga, iwe unoda kubvunzurudzwa kwechiremba wekutanga-ipapo ngozi yemigumisiro ichaderedzwa.