"Pomalidomid" (imnovid): mutengo dzomuzana. Sezvo isingadhuri kutenga "Imnovid"?

Pomalidomid - ndiwo mushonga rinopiwa chizvarwa chitsva Anti-bundu zvirwere modulators. Izvi zvinhu ane mano tunodzivisa stromal (hunde) masero kuti inotsigira kukura uye kukura myeloma. Uyezve, rinoita apoptosis (chiite rufu masero chakaremara) uye kuchititadzisa kuwanda (zvinyama kukura).

Ongororo nekusimba kuti kuburikidza kushandiswa pomalidomida 52% kwakaderedza mwero kunoita uye upenyu anotarisirwa zvakati kwakawedzera.

Rinorondedzera fuma anzverwa muna US nokuda pakurapa refractory vakawanda myeloma uye watangazve. Ikoko richiwanikwa pasi kutengeswa zita "Pomalist" sezvo anozikamwa EU se "Imnovid".

Ndingawana kupi kutenga zvinodhaka isingadhuri tune pomalidomid

Tisati mberi rondedzero chiito pomalidomida, zvinofanira kucherechedzwa kuti mishonga inodiwa pakurapa kenza, muri zvinodhura. Uye dambudziko varwere ndechokuti kudimburira kurapa hapana nzira asi mari yose nzira - iri matambudziko chaizvo. Saka, muMoscow pamusoro vakapiswa chinodhaka ine pomalidomid mutengo anoramba kumativi 819.000 rubles.

Pakadaro, uchasvika kubatsira inozivikanwa www.onko24.com nzvimbo. Pano unogona kutenga zvinodhaka Generic ane chete rinoita chirungiso - pomalidomid, mutengo uri pamusoro pavo panguva imwe chete richava zvikuru inokwanisika. Uye ichi hachisi kukonzerwa kushata rekugadzirira, uye kuti akakurumbira Indian kambani inobereka nayo, hazvina zvakakodzera kushandisa pakutsvakurudza, kukura uye pakushambadzira. Iye chete vakatenga kodzero pave mushonga, iro rinotsanangura ayo tichishandisa mari shoma, pamwe chete kunyatsoshanda.

Dosing gadziriro uye dosing

Pomalidomid akaratidza pakurapa varwere makore 18 kana vakura, vane zvinooneka kunoita refractory vakawanda myeloma kutevera zvinenge 2 yamabwe kurapwa pamwe bortezomib uye lenalidomide.

Shandisa mudziyo mukati, pamwe dexamethasone, 4 MG kamwe zuva nezuva, nokuti mazuva 21, pashure aida kuregawo kwevhiki.

The mushonga chinofanira kuitwa chete mumaawa ose zuva, zvisinei zvoupfu nguva. Kutsenga kana apwanye capsules hazviiti. Kana imwe nhano asiyiwa, ipapo rakatevera zuva havafaniri kunwa dose kaviri.

With kuchiita kurapwa maperembudzi akarembedzwa.

Contraindications

Regai taurira zvinodhaka zvine pomalidomid, vana pasi pemakore 18 nevakadzi vane pamuviri. Achiyamwa panguva kurapwa inonzi mumiririri anofanira vakarega.

Mamiriro varwere renal uye hepatic vanotaura inofanira kuongororwa nachiremba wako mangwanani kuziva miedzo nenjodzi.

divi kushanda

(. "Imnovid", "Pomalist", etc.) Kana kurapa kugadzirira ane pomalidomid, okuti zvinotevera nemigumisiro kunogona kuitika munguva varwere:

• nekuneta;
• panowanikwa musoro, dzungu, uye kuvhiringidzika;
• kuda kurutsa, kurutsa;
• kurasikirwa havi;
• Gastrointestinal zvirwere kushanda;
• kupererwa, thrombocytopenia;
• panowanikwa tsandanyama chinyamunhari chinorwadza uye kurwadziwa mu mapfupa;
• Kugadzirwa zvinotapuriranwa vaikudzwa kufema turakiti;
• mapundu.