Yokupedza - chii ichi? Features

It yagara vakafunga kuti gastric kwezvakatipoteredza pfupi chena dzinogarisana payo microflora. Mudumbu, yayo womukati kugutsikana - acid, kana kungoti haana kurarama chimwe muviri. Kuziva miedzo Helicobacter pylori ari nemudumbu yave revolutionized pfungwa yezvakaita gastrointestinal zvirwere: gastritis, duodenitis, gastric maronda uye duodenal maronda, gastrointestinal kenza uye zvavo kurapwa. Munyaya ino tichakurukurei muudzame chii yokupedza. Zviri nzira chaiwo kurapa yava mukurumbira chaizvo mumakore achangopfuura.

Karwendo kupinda munhoroondo Helicobacter pylori

Kutaura zvazviri, utachiona yakawanikwa nguva refu uye kwete kamwe. Kokutanga ichi chakaitika pakupera rokupedzisira remakore. Yakanga 1886. Professor Jagiellonian University V. Yavorsky wanikidza utachiona mamirire zononoka chimiro ari gastric zvinhu. Akapa zita utachiona Vibrio rugula, uye pfungwa kuti wakakurira ingaita kukura gastric zvirwere.

Zvisinei, ruremekedzo handihwo Yavorsky basa zvokurapa. Makore manomwe gare gare, musayendisiti Italian D. Bidzodzero vakachera zvigare zvakadaro kubva zvomudumbu turakiti rembwa. Akatevera, uyo akaona kuvapo utachiona mudumbu masero kubva varwere maronda vakavhiyiwa akanga Purofesa Morozov Moscow. Atova pakuguma 70s remakore rapfuura.

Uyezve kuedza kutsanangura zvimwe, patsanura, kukura murabhoritari uye kuongorora kusazivikanwa utachiona kwave ashandiswe muna 1979 uye 1981 vokuAustralia Marshall uye Warren. Uye vakabudirira. Marshall akaitwa vabudirire ruzivo yokuzvidzora hweHIV Helicobacter pylori nokuporesa helicobacter gastritis akawana kosi rwemavhiki maviri kurapwa ne "metronidazole" uye bismuth munyu.

nzira iyi anoumba hwaro ano yokupedza nayo Helicobacter pylori. A vakashinga vatsvakurudzi muna 2005 vakagamuchira Nobel Prize muna Medicine.

Zita Helicobacter pylori muviri raiva 1989, uyewo tsananguro yakakwana uye kupatsanura. Spiral Utachiona dzinogarisana akasarudza "wegedhi" mudumbu ( "pylori" - kubva Greek "wegedhi") hwacho munzvimbo dzose duodenum uye mudumbu. In chikamu chinokosha zvose gastritis, duodenitis, intestinal maronda uye duodenal maronda kusvikira kenza yavo nemhosva microorganism ichi.

The ngozi chirwere pamwe Helicobacter pylori?

Helicobacter pylori, ugere nemudumbu womunhu kana mhuka kuti pores achiita anenge. Kuchangotanga kukundikana iri zvirwere kana tinofanira kugara mugumisiro kwekwashi kana hakuvaki tsika kusashanda utachiona anova hasha. Chii ngozi? Vaigara mucous Kamudzira of zvomukati - dumbu uye duodenum - pathogenic microorganism chiito pamusoro payo.

Kunotangira zvakawedzera kusunungurwa wezvakavanzika, izvo kwakakanganisa kunokanganisa gastrointestinal tishu. Mucous navo Anova unzenza, nokuputswa, pane zvikuru zvomoto nzvimbo nokuumbwa nemaronda. Chirwere gastritis anokonzerwa pathogenic microorganism Helicobacter pylori boka, kusafanana kwakajairika zvokuimba gastritis, havasi amenable kurapa kwakajairika nzira.

Helicobacter pylori chinopinda zvose chakadzama akaturikidzana ose zvinyama, nokudaro dzisisina kwemishonga inorwisa mabhakitiriya akawanda (mishonga dzinotsauka kuti acidity). Kwakadaro vandalnye varo zviito zvinokonzera kusingarapiki pezvakaitwa ari mucosa Somuenzaniso, imwe precancerous mamiriro uye, zvakananga, kukura oncology. Kuti izvi zvisaitike, kushandisa yokupedza nayo Helicobacter.

Chirwere pamusoro Helicobacter pylori ari nemudumbu

Kana murwere anonyunyuta kuti kuda kurutsa uye fufune, chirungurira, marwadzo, nezvinetso cheya, chinorwadza kusagadzikana munyika epigastric dunhu - zvakananga chiratidzo kuti kuedzwa kuti kuvapo nhengo Helicobacter pylori. Inoongorora rendi vari:

• ropa, mukuru Kuongororwa ane antibody, kusanganisira kuvapo H. pylori;
• chitsiko kuongorora kuvapo kwemabhakitiriya tsvina;
• mweya bvunzo hwakavakirwa Kutsunga amoniya wevasungwa munguva nedzinovengwa;
• cytologic ongororo.

Chakavimbika kupfuura nzira diagnosing maperembudzi ari zvinyama biopsy pamusoro gastric mucosa uye duodenal maronda. Mucheka uyu akatorwa nokuda ongororo kubudikidza endoscopy.

zvairatidza yokupedza

Sezvambotaurwa pamusoro, yokupedza nayo - inzira hwokubata gastric utachiona.

Yokupedza vatakurira kunze varwere munzira pathologies dzakadaro:

• urikanwi Zviratidzo mudumbu uye duodenum;
• chinzvimbo romukova resection (kuvhiyiwa kubvisa kenza);
• precancerous inoti vane miviri tishu atrophy;
• rwekenza yelymphoma.

Pangozi muri vanhu vane hama vakatambura kenza. Recommended yokupedza kurapa uye varwere gastroesophageal reflux chirwere uye dzichipfekeka dyspepsia.

yokupedza nzira

Yokupedza - ndiko kuparadzwa, yokupedza (Chirungu yokupedza.). chiyero ichi, zvakagadzirirwa kuparadza chirwere pamwe Helicobacter pylori nemudumbu. The nzira kurapwa unoratidzwa varwere zvakakomba gastric urikanwi kana duodenal urikanwi. Chaizvoizvo Its iri kosi yaunodya mishonga iri muenzaniso chaiwo.

Risati ratanga kosi yacho inoitwa mamwe kudzidza gastric mucosal rinenge kuvapo masero nyanyisa.

Helicobacter pylori yokupedza ane mhando dzakawanda:

• monkey, apo kushanda pakurapa kugamuchira nzira imwe chete, kazhinji medicaments inobva bismuth munyu, kana mushonga unorwisa;
• Vaviri, Dual kurapa (vismutosoderzhaschee fuma ndinoiitawo mushonga);
• triplet, sezvo zita rinoreva, kurapwa ichi zvinodhaka nhatu (bismuth, mushonga unorwisa uye mumiririri imidazole boka);
• kvadriplet, vanoumba mana, sezvamakaropafadzwa kunzwisisa triplet akawedzera PPI kurapa (blockers ose hydrochloric acid).

Mono-yokupedza - izvi zvinenge hatibati kurapwa nzira nokuda ineffectiveness kwayo (pazasi 50%). Akanga ari mufashoni panguva mambakwedza hwomukova uye vokutanga kuedza helikobakterialnoy vaitire hweHIV.

Yokupedza kushandisa mishonga maviri ane kunyatsoshanda kuti Kuraswa helicobacter vanenge 60%, uye zvishoma muna chaizvoizvo yanhasi kwaiitwa. Chii kushandiswa nhasi yokupedza? Treatment regimens anoshandiswa.

Tripletoterapiya inosanganisira bismuth remubatanidzwa, mushonga unorwisa (amoxicillin uye kuwedzera kushandiswa klaritomitsin) uye imidazoles (ichi fungicides).

Nzira zvinodhaka zvina - zvose zviri pamusoro Formulations ndinoiitawo hwepurotoni pombi FIs (ichi boka antiulcer zvinodhaka zvainanga yokuderedza gastric iine acid production). Nzira ayo kunyatsoshanda vari waivako indices 90% uye 95% azvaitwa. Heano inobudirira yokupedza nayo Helicobacter anogona kuva.

Mishonga inoshandiswa yokupedza

Nokuti acidic kwezvakatipoteredza anokonesa zvinokonzerwa mishonga yakawanda inorwisa mabhakitiriya, mazita mishonga kuti vabvise zvikuru pfupi:

• mishonga;
• antiinfectives;
• vismutosoderzhaschie zvinodhaka;
• hwepurotoni pombi FIs;
• probiotics uye prebiotics.

Mishonga inorwisa utachiona zvikuru yaiwanzoshandiswa yokupedza kurapa

How kutanga yokupedza? Mishonga ndeizvi:

• "Amoxicillin" kana "Flemoksin Soljutab" - kuti penicillin boka, ari yakakodzera varwere vakawanda havana pachii kushandiswa panguva pamuviri, renal kukundikana.

• "Amoxiclav" - mubatanidzwa amoxicillin uye kavulonovoy acid, ari broadest chakarondedzera mushonga inokurudzirwa kungwaririra kurishandisa mune murwere itsvo pathologies, panguva yepamuviri mushonga zvinokonzera zvikuru dysbiosis.
• "Clarithromycin" kana "Klatsid" - pasi chepfu asingaurayiwi erythromycin boka siyana zvikuru yakakurumbira nokuda yokupedza, iri contraindicated mu vacheche kusvikira mwedzi mitanhatu, vakadzi vane pamuviri, kushandiswa nokungwaririra pavarwere vane renal kana hepatic insufficiency.
• "Azithromycin" - rinogona kutsiva "Klaritomitsinu" shoma nemishonga, zvisinei, zviri zvishoma inobudirira pamusoro helicobacter pylori.

Mishonga "tetracycline" uye "Levofloxacin" anoshandiswa nezvahwo uye avo zviitiko apo mishonga dzataurwa pamusoro apa vasina achida mugumisiro. Formulations tetracycline boka zviratidzwa hasha chiito tichitarisa nemishonga pashure yokupedza nayo Helicobacter, saka kashoma kushandiswa.

Antibacterial uye Anti-infective zvapanzvimbo yokupedza

"Metronidazole" - Anti-infective chemotherapeutic mumiririri nitromidazolovoy boka, chepfu chaizvo, kuomerera haawirirani doro uye wakarambidzwa panguva yepamuviri.

"Makmiror" kana "Nufuratel" - imwe antibacterial zvinodhaka, rinoshandiswa pakuparwa kukundikana "Metronidazole".

Vismutosoderzhaschie zvinodhaka

"De-Nol '- ndizvo mushonga akaratidza soro mwero neutralizing kuona Helicobacter. "De-Nol 'urwa uye anopinda bile nebhitumini mu zvakadzamisisa akaturikidzana pakati njodzi nenyere. Negative divi migumisiro ine anenge asina, uyewo contraindications (kunze, dzinozivikanwa, nhumbu).

Zvishoma yaiwanzoshandiswa pakurapa Helicobacter roMunyu bismuth yeimwe:

• bismuth subsalicylate;
• bismuth subnitrate.

Kugadzirira inobva bismuth munyu akashandiswa pakurapa gastrointestinal zvirwere, pamberi pakuvhurwa Helicobacter pylori. yeimwe ava nemishonga acidic ezvinhu mudumbu. Bismuth yeimwe pamusoro mucosa zvakakuvadza pamusoro kuumba inodzivirira firimu kubva kungatikanganisa kwezvakatipoteredza, kuderera acidity uye pave mangwanani scarring kuti sei hukawanika.

Kana iwe kuzarura Helicobacter pylori bismuth yeimwe akaratidza zvinoshamisa zvainoita kudzvinyirira uye kuparadzwa ichi kunyanya mabhakitiriya.

Formulations gomba boka akashandiswa yokupedza

hwepurotoni pombi FIs (PPIs) inokosha zvikuru kunzwisisa nomugumisiro Helicobacter pylori. PPI zvinodhaka vane rudzi antacid maturo, kunoderedza sehasha yacho iine acid kwezvakatipoteredza. Utachiona Ongororo dzakaratidza kuti kubva acidic kwezvakatipoteredza chafa. Nokudaro, PPI asike saregerereka ezvinhu kuti hwomutambarakede kuvapo mabhakitiriya ari kunzwisisa pamwe bismuth, "metronidazole" uye mushonga kunowedzera kubudirira yokupedza nayo Helicobacter pylori kusvika 95% uye pamusoro. mishonga Idzi dzinosanganisira:

• "Omez" ( "omeprazole");
• "Nolpaza";
• "Rabeprazole";
• "Pantoprazole" uye nezvakadaro.

kureva "Omez" basa kakawanda. Blockers kana hwepurotoni pombi PPI DZEMUNHU DZINODZORA basa secretion Inosanganisa mumasero.

Normalization of zvomudumbu turakiti microflora pashure yokupedza nayo Helicobacter

Kusangana nemishonga kazhinji, ndiko anokanganisa muura uye mudumbu. Naizvozvo, pashure yokupedza nzira zvakafanira kurerutsa kwakonzerwa kune muviri. Kuti aite izvi, pane anobatsira zvigadzirwa zvakadai probiotics kana prebiotics, kuratidzwa panguva dysbacteriosis, flatulence, manyoka, etc. Izvi zvinosanganisira .:

• "Laktoferon";
• "Linex";

• "Hilak Forte";
• "Bifidumbacterin";
• "Atsipol" uye nezvakadaro.

Probiotics uye Prebiotics - vangasimudzira werumwe, chichinyatsobatanidzwa kureva basa nemumwe. Mapoka acho ane kunobatsira pamusoro muviri kuburikidza normalizing ari intestinal kasvisto. Musiyano pakati pavo kuti probiotics - mhenyu tsika kunobatsira tusingaoneki. Prebiotics chete - Organic makemikari. Chokutanga zvakananga "zvikure" munhu akafa microflora, wechipiri - kusika akanaka ezvinhu izvi. Zvechokwadi vanofanira kutora pashure yokupedza.

dziviriro chirwere

Helicobacter pylori Isimba rakadini rinogona kubudiswa keriya angava nomumwe. The microorganism anogara mudumbu, ura uye kunanzvana mhango womunhu kana mhuka kwemakore uye asingauyi unooneka.

Activation mabhakitiriya kunoitika nokuda zvirwere kukundikana pasi kushushikana, zvinokuvadza (doro, kusvuta), kudzikama kudya uye epigastric marwadzo hworatidza pacharo. Dzimwe Helicobacter anogona kukanganisa chiropa.

mhedziso

Kusvibiswa kubva nhau chirwere kunoitika kuburikidza kuonana kana kuburikidza nokushandisa mudzimba nyaya. Unofanira kunyatsoongorora kutevera mitemo utsanana, kuitira kurerutsa kusvibiswa yechitatu-party. Zvadaro haatarisiri yokupedza nayo Helicobacter pylori.