"Zanidip": mirayiridzo kushandiswa, varwere chaivo uye n'anga dzomuzana. "Zanidip-Rekordati": richitungamirira, wongororo, analogs

Maererano nenhamba, vanenge 26% vanhu vakuru munyika vanotambura cheBP dzose. Kakawanda chirwere ichi chiri chokuita nemagene kubatwa. Zvisinei, pane zvimwe zvikonzero parinowanika. Izvi zvinosanganisira kufutisa, kusvuta, kunyanya kudya munyu, kushaya zvisaririra zvinhu uye mavhitaminzi mumuviri, doro, kushushikana, pasi kurovedza muviri, uye vamwe.

Zvinofanira kucherechedzwa kuti kukura neBP kunobva zera remunhu wacho. Mukuru ndiye, ari kumusoro ngozi zvakadaro pathological ezvinhu. Pazera makore 40, chirwere chacho rinenge nguva dzose pamusana sclerotic vascular maronda.

Vhuṱanzi

Kakawanda, vanachiremba vakaisa varwere vavo nechirwere "zvinokosha neBP". Chii? Zviri ane chirwere uye rudzi neBP. kurapwa yake huru chiratidzo anoita kuramba uye mazhinji pakukwirira BP.

Zvakachinja chirwere chakadai angava akasiyana. Zvisinei, havana kunyanya chokuita tsinga uye mwoyo.

Kuti kuvandudza murwere ezvinhu, vanachiremba vanokurudzira zvinodhaka ichi se "Zanidip". Reviews wevarwere pamusoro kubudirira zvinodhaka ichakurukurwa munyaya zvinhu ino. Uyewo ikoko uchawana mashoko pamusoro sei kugamuchira vakati mishonga, kana akanga chero analogues nemishonga.

Description, akafanana, chimiro uye kavha

The medicament "Zanidip" mirayiridzo inochengetwa imwe makadhibhokisi svinga iri asunungurwa muchimiro mahwendefa Chiedza yeyero uye kumativi uye biconvex siyana mucherechedzo rimwe kumativi. Ndivo film-Coated uye vane yellowish tint pamusoro yokuzorora.

The vanoshingaira wemafuta zvinodhaka ichi anoita lercanidipine hydrochloride. Uyewo, unosanganisira uye ebetsero zvinoriumba, izvo achimiririrwa povidone K30, lactose monohydrate, yavaibvisa carboxymethyl starch, microcrystalline cellulose uye magnesium stearate.

Panyaya film-unhani Pfungwa, zvino rinoumbwa zvinhu zvakadai Opadry Yellow, talc, hypromellose, titanium dioxide, simbi oxide dhayi yeyero uye macrogol 6000.

Buy "Zanidip" mapiritsi ari mhoni packs it angava, kuti inoiswa mumabhokisi mapepa.

Pharmacological zvechadenga zvinodhaka

Wanga uchiziva kuti ari chinodhaka "Zanidip"? Instructions ari kushanda kunoratidza kuti iri karusiyamu chiteshi blocker kunonoka. Its kushingaira chirungiso chinhu racemic musanganiswa wacho dextro-uye levorotatory stereoisomers. Zvinofanira kucherechedzwa kuti rinobva 1,4-dihydropyridine.

medicament ichi zvokusarudza ichivharira kuitika calcium ions muzvitokisi cardiac, masero vascular kumeso tsandanyama.

Nheyo kuramba antihypertensive maturo zvinodhaka imhaka zvakananga relaxant kwakabatsira vascular mvere tsandanyama masero.

Maererano mirayiridzo, paakaudzwa kuchirapa mugumisiro wacho medicament kunoitwa pashure pemaawa 5-7. Nguva yaro ukoshi anodzokororwa yose zuva.

Nokuda mukuru selectivity zvinodhaka kune vascular wakatsetseka tsandanyama masero, hapana kuva akaipa inotropic kushanda.

Saka chii chinonzi zvinodhaka "Zanidip-Rekordati"? Guide inoti kuti metabolically zvematongerwo mushonga kuti haana simba zvikuru zviri apolipoproteins uye lipoproteins neropa serum, uyewo haachinji nhoroondo yomunhu mafuta vanhu vane BP.

The kinetics zvinodhaka

Kunyura kupi mushonga "Zanidip"? Mirayiridzo dzokushandisa kuchaita Anotiudza kuti mushure mekugamuchira mahwendefa (10 kana 20 MG) nechomukati lercanidipine raisangoita anenge zvachose kubva nemudumbu. Mushure memaawa 1.5-3 kufadza wevasungwa zvinodhaka munyika plasma rinosvika ane ukoshi 3,3 kumar / Rine mamiririta kana 7,66 kumar / ML azvaitwa.

Riparadzirwe zvinodhaka mune nyama uye nhengo kuchiitika nokukurumidza zvikuru. Kukurukura mapuroteni eplasma kukasapfuura 98%. Akadzokorora dose mahwendefa kuwanda kwavo kuchengetwa.

The muviri zvinodhaka rinoitwa munguva wokutanga Pfuurai chiropa. Izvi zvinoitika kuburikidza biotransformation CYP3A4. Izvi zvinoita dzinoverengeka metabolites asina pharmacological basa.

Akaratidza mushonga "Zanidip", wongororo iyo dzinoturwa zvishoma kudzika kuburikidza ura neitsvo. Pane zvikamu zviviri nokubviswa lercanidipine: mangwanani ane nguva iri maawa 2-5 uye chokupedzisira - maawa 8-10.

The kuchinja mushonga ari kushanda asina kuona ari mutsvina yadzo weti uye.

Vanhu vane chiropa kana renal chirwere mapuroteni zviri plasma iri yekudyidzana ipfupi. Panyaya iyi, vakasununguka chikamu yezviri zvacho medicament anogona kunyanya kuwedzera.

Zvairatidza kuti kurapwa

Nokuti chinangwa chinogona kupiwa mishonga "Zanidip"? Reviews kuvarapi akashuma kuti mumiririri uyu zvinobudirira rinoratidza pacharo mune zvinokosha neBP uye nounyoro kuti zvive nomwero nekuomarara.

Contraindications kugamuchira mapiritsi

Maererano mirayiridzo, mushonga "Zanidip" hakufaniri kutorwa pasi zvinotevera ezvinhu:

• zvakakomba chiropa basa;
• chisingaperi mwoyo kutadza hunhu (kunyanya decompensation danho);
• vasingadzoreki renal basa;
• kusagadzikana angina ;
• akabatana simba FIs isoenzyme CYP3A4 (somuenzaniso, "ketoconazole", "erythromycins", "itraconazole") uye ne "cyclosporin" uye bhuratifuru muto;
• panguva pamuviri;
• mhingaidzo midziyo ropa kunobva rworuboshwe ventricle mumoyo;
• lactose kusashivirira, lactase kwezvokudya uye malabsorption chirwere galactose / shuga;
• paanenge achiyamwa;
• ichangopfuura nokuda myocardial infarction (munguva romwedzi mumwe);
• Women pazera rokubereka vasiri kushandisa yakavimbika nzira pamuviri;
• pasi zera (efficacy uye kuchengeteka vasina dzakatangwa);
• hypersensitivity kuti lercanidipine uye mamwe dihydropyridine nomukaka kana chero zvinoumba mishonga.

Vakangwarira paakatora mishonga

The medicament "Zanidip-Rekordati" yambiro inokurudzirwa kutora vanhu vane havachanyatsogoni chiropa mashandiro (mwero uye vanyoro), chirwere mwoyo nedostatochnostyusindromom sinus, kuruboshwe ventricular kukundikana uye coronary tsinga chirwere, uye mawa kugamuchira "Digoxin" Beta-blockers.

Mahwendefa "Zanidip": mirayiridzo kushandiswa

Tichifunga vakawanda yaivhuvhuta zviitiko vaiona zvinodhaka kunofanira kutarisirwa ruzivo vashandi. Kazhinji, zvinoshingaira zvinodhaka inokurudzirwa kutora munzvimbo mari 10 MG kamwe pazuva.

Mapiritsi yaifanira mangwanani, nokuti ¼ awa pamberi kwemangwanani.

Zvichienderana kuchirapa mugumisiro pamusoro chipimo chemushonga zvinodhaka pasi kukurukurwa inogona kaviri, i.e. kune MG anenge 20. Kuwedzera mishonga ine medicament ikaitika zvishoma nezvishoma. Kana waida, kuwedzera uwandu medicament kuitwa pashure pemavhiki maviri pashure mharuro mushonga.

Ndinofanira kutora "Zanidip-Rekordati"? Regai dzinodzeya mahwendefa. kazhinji ivo akamedza uye ndikandoshamba pasi aine zvakakwana uwandu emura.

In vakwegura No chipimo chemushonga kuchinja kunodiwa. Asi kana kunwa mushonga wavo ezvinhu kunoda nguva zvichiongororwa.

In pamberi hepatic kana renal kukundikana kana mwero nekuomarara chipimo chemushonga kururamisa hakuna kuzvireva. Mumazuva zvinodhaka raitongwa ari mari 10 MG, okutanga shoma uye ipapo nokungwarira kuwedzera dose kusvika 20 MG pazuva.

Kana antihypertensive mugumisiro wacho zvakasimba akaratidza kuti yakati uwandu husingakuvadzi ipfupi.

nemishonga

Anogona kukonzera Maitiro zvisingadiwi "Zanidip-Rekordati"? Consumer ongororo kukuzivisai kuti kudya izvi zvinoreva kuti dzichitaridzika nemishonga. Chii chaizvo, isu funga zvino:

• Rokuzvidzivirira: Hypersensitivity.
• Kumwoyo:, tachycardia, angina, palpitations, kufenda, Flushing kune chiso ganda, chipfuva kurwadziwa akacherekedza zvinoderedza BP, chirwere chemwoyo.
• Tsinga: somnolence, nomusoro, dzungu.
• Zvomudumbu turakiti: kurutsa, dyspepsia, kuda kurutsa, reversible kuwedzera chiropa makemikari, manyoka uye abdominal kurwadziwa.
• Skin nekumhanyirira.
• Zvetsandanyama nemapfupa maitiro: myalgia.
• Urinary: polyuria.
• Other: peripheral edema, kurukutika, gingival hyperplasia isiri yekenza, kurukutika.

Zviratidzo ovhadhozi

Chii migumisiro zvichatevera, kana ukawana yepamusoro mishonga yacho zvinodhaka "Zanidip"? Guide rinodonongodza zvinotevera zviratidzo ovhadhozi: myocardial infarction, dzepanguva tachycardia, peripheral vasodilation pamwe nemuumbi kuderera BP, nokuwedzera nguva uye kakawanda angina kurwiswa.

Kubvisa vakadaro inoti symptomatic kurapwa.

zvinodhaka kwavatori

Zvinoita chokubatanidza nevamwe zvinodhaka mushonga "Zanidip"? Mirayiridzo yokushandisa kunoratidza kuti chishandiso chinorambidzwa chokubatanidza kwakadaro FIs CYP3A4 (cytochrome P450 chiropa), sezvo "Itraconazole" "ketoconazole" uye "erythromycin". Izvi imhaka yokuti mishonga izvi zvose kuwedzera wevasungwa kuti lercanidipine muropa, uyewo achitungamirira antihypertensive mugumisiro.

Mawa kugamuchirwa haberleri zvinoreva iri kuti "cyclosporin" contraindicated, sezvo kungaita kuti nokuwedzera zviri zviviri zvinhu muropa zvomurwere.

Lercanidipine hakubvumidzwi kushandiswa pamwe bhuratifuru muto. Kubatana uku kungaguma potentiation pamusoro antihypertensive mugumisiro lercanidipine uye chinovhiringidza kuti muviri.

Zvinofanira kungwarira zvikuru apo pakugamuchira "Zanidipa" zvinodhaka akadai "Astemizole", "Terfenadine" uye "quinidine", uye zvakare antiarrhythmics vekirasi wechitatu (semuenzaniso, "Amiodarone").

The ibatanidzo vaiona medicament pamwe anticonvulsant zvinodhaka ( "phenytoin," Carbamazepine ") uye" rifamycins "anogona kukonzera zvinoderedza ropa kwevari lercanidipine, zvikaguma kuderera pamusoro antihypertensive mugumisiro lercanidipine.

Kana mushonga akabatana "Digoxin" vanofanira kuramba kuongorora zviratidzo kudhaka.

Mawa kurapwa pamwe medicament "midazolam" vakura kungawedzera absorbability kuti lercanidipine uye kuderedza ayo Absorção de Água unodiwa.

Nyanzvi dzinoti "metoprolol" anokwanisa kuderedza bioavailability kuti lercanidipine 50%. Panyaya iyi, iyo bioavailability kuti "Metoprolol" anoramba kuzochinja. Izvi zvauya kubva kuderera ropa riyerere hepatic kunokonzerwa Beta-blockers.

Kugadzirira "Cimetidine" ari chipimo chemushonga vana 800 MG pazuva rega kuguma kuchinja muropa wevasungwa kuti lercanidipine. Asi panguva kugamuchirwa wayo zvinoda kungwarira chaiyo, sezvo mukuru mishonga kungawedzera bioavailability kuti lercanidipine uye somugumisiro kuwedzera ayo antihypertensive kushanda.

Tiine wemishonga "Zanidipa" ne "Simvastatin" chinodhaka rokutanga kubatwa mangwanani, uye wechipiri - manheru.

The medicament "fluoxetine" asina zvainoita kinetics ose lercanidipine.

Mawa kugamuchira "Zanidipa" ne "warfarin" haana kukanganisa pharmacokinetics okupedzisira.

Of Mari inogona pamwe diuretics, Beta-blockers uye ACE FIs.

Tinofanira kuonawo kuti panyaya iyi runogonesa kuti antihypertensive mugumisiro lekarnidipina.

chaizvo kurumbidza

Drug "Zanidip", analogues iyo dziri pasi apa, zvinofanira nokungwarira kunyanyisa mune vanhu vane vasingadzoreki itsvo nerevane coronary tsinga chirwere, sezvo iyi, pane mukana mukuru yakawedzera kakawanda angina kurwiswa.

Asati kugamuchira mushonga nguva dzose inofanira ndanyarara hangu mwoyo kutadza chirwere hunhu.

Kunyanya kungwarira chinofanira kuchengetwa kumavambo yokurapa, kunyanya pavarwere vane mwero uye nounyoro mwero hepatic insufficiency.

Panguva kurapwa, zviri chinodiwa nokungwarira basa kuti rinoda vainyatsotarisirwa, kusanganisira mugwagwa zvakanaka. Izvi imhaka yokuti pakutanga kurapwa uye zvinopfuura mishonga kune njodzi panowanikwa nemusoro, hope uye dzungu.

okuchengetera zvinhu, ari pasherefu upenyu rekugadzirira uye kutengeswa

Ndingawana kupi kutenga mapiritsi "Zanidip-Rekordati"? Analogs of mari pachake mishonga inotengeswa chero chezvinodhaka. Zvisinei, vanogona kutengwa chete chiremba mushonga.

Rambai mushonga uyu pasingasvikirwi chinodiwa kuti vana vaduku apo tembiricha asingadi kupfuudza madhigirii 30.

The pasherefu upenyu mushonga pasi kufunga makore matatu. Shure iyi, kunwa mushonga hakubvumidzwi.

zvinodhaka analogues

Unozviziva kuti unogona kutsiva mapiritsi "Zanidip"? Analogues kuti chokushandisa iyi zvakaoma kuwana. Nyanzvi dzinoshuma kuti zvakafanana zvivako uye kushanda gadziriro yakadaro ive "Lerkamen" uye "Lercanidipine". Mishonga izvi zvinofanira chete kuva mazano ezvokurapa.

Drug "Zanidip": wongororo wevarwere uye nyanzvi

Zviri chaizvo antihypertensive mumiririri. Kuti maonero izvi vaiita navanachiremba vazhinji. Tinobvumirana navo, uye akapotsa zvose varwere kunwa mapiritsi "Zanidip". Vanoti pashure kutora mushonga chaizvo avo ezvinhu akavandudzika. Zviratidzo zvinokosha neBP riri pakati nepakati kukuvadza siya dzinenge pakarepo.

The chete drawback mishonga iyi kuti kuushandisa kwazvo kunowanzokonzera marwadzo, kunyanya pamusoro chikamu zvomudumbu turakiti uye kumwoyo.

Zvinofanira kucherechedzwa kuti vanhu vakawanda vanotsutsumwa pamusoro mutengo zvinodhaka hahusvikirwi. mushonga uyu ari uwandu mahwendefa 28 inogona kutengwa 450-500 rubles. Zvinofanira kucherechedzwa kuti analogues ose akati medicament muchimiro "Lerkamena" uye "lercanidipine" haana isingadhuri. Vanogona kutengwa nokuda chete mutengo.

Nyanzvi dzinoti mari "Zanidip" antihypertensive mushonga zvakazara sezvarayirwa unhu kwayo. Zvinoratidza zvinenge zvose ake ruzivo refu ari kushanda.