Antidepressant "Velaksin": Murwere uchapupu, mirayiridzo kushandiswa, analogs

Ndinogona kutenga antidepressants pasina mushonga? A pamazita zvigadzirwa zvakadaro hakusi guru. Izvi imhaka yokuti vanogona kuva muropa, uye boka nemishonga. Saka, asati kutora nzira yakadaro, iva nechokwadi kuti kushanyira nyanzvi.

Vhuṱanzi

Kuora mwoyo isina kurapwa nezvinodhaka. Asi kuvandudza kushanda tsinga, vanachiremba vakawanda vachiri varayire avo varwere siyana antidepressants. Mumwe wavo ari chinodhaka "Velaksin". Testimonials pamusoro ichi chombo uye mamiriro ayo uye mirayiridzo kushandiswa zvichakurukurwa pazasi.

The Kuronga chinodhaka, wawo okuwana

In chii chimiro inobereka ive antidepressant se "Velaksin"? Mahwendefa uye capsules - ndivo chete siyana chezvinodhaka.

Mahwendefa "Velaksin" vari chena, rwakatemwa kurutivi rumwe "E741", uye raundi sandara chimiro uye chamfer. Ravo rinoita chirungiso ndiko venlafaxine, uko kunomiririrwa ari muchimiro hydrochloride. Inosanganisirawo mishonga iyi anosanganisira ebetsero zvinoriumba akadai colloidal silica anhydrous, lactose monohydrate, yavaibvisa starch glycolate, magnesium stearate uye MCC.

Ndokurongedza mahwendefa mhoni packs it uye makatoni azvaitwa.

Drug "Velaksin" - capsules, mirayiridzo kushandiswa zviri akanyudzwa kavha, bepa, gelatin uye rakasimba. Vane Orange mashava chivharo uye Hauoneki substrate. The vanoshingaira chezvinonhuwira fomu iri uyewo remubatanidzwa venlafaxine. Kuwedzera rwiyo rwake kurapwa ichi zvinosanganisira zvimwe zvinhu.

Sezvo chinodhaka mabasa?

"Velaksin" - chizvarwa chitsva Anti-depressant. Maererano makemikari maumbirwo chacho vanoshingaira fuma haagari chero kirasi wakazikamwa antidepressants (semuenzaniso, tricyclic, tetracyclic, kana zvimwe). Nyanzvi vanoti mushonga rinoshanda enantiomer 2 racemate.

Pfungwa chiito zvinodhaka uyu yakabatana kukwanisa rayo potentiate ari CNS etsinga chido hutachiwana.

Maererano mirayiridzo, venlafaxine chacho chikuru metabolite (Efa kana O-desmetilvenlafaksin) zvinomiririra simba FIs pamusoro reuptake ose norepinephrine uye kweserotonin simba FIs ose dopamine reuptake. Hatigoni kutaura kuti izvi zvinhu anogona kuderedza Beta-adrenergic basa pashure mishonga imwe chete uye kugara. Efa uye venlafaxine vanoitirwawo inobudirira pamusoro reuptake pamusoro neurotransmitters.

Chiizve chinoshamisa zvinodhaka "Velaksin"? Guide inoshuma kuti yezviri wemafuta mushonga ane nokushamwaridzana n- uye M-cholinergic receptors, uropi α1-adrenoceptors uye histamine H1-receptors. Uyezve, zvinoita kuchititadzisa kuitwa Mao uye haana kufanana ne fentsiklidinovymi, opioid, benzodiazepine uye NMDA-receptors.

The kinetics zvinodhaka

kana mushonga wefodya, "Velaksin" (Mahwendefa)? Mirayiridzo Dzokushandisa inoti yezviri chezvinonhuwira zvinodhaka ichi wefodya kwazvo kubva dumbu. Pashure chete dose kuti medicament ari chipimo chemushonga pamusoro 25-150 MG pamusoro soro mumisasa yacho muropa zvasvika pashure maawa 2,4. Saka venlafaxine ari nezvo rinoita panguva yokutanga Pfuurai chiropa. Kana mushonga chinobviswa zvokudya, apo Parainge wevasungwa inowedzera kubudikidza maminitsi 27-30 mu plasma.

Huru metabolite anoonekwa nzira O-desmetilvenlafaksin. Its hafu-upenyu uye kubviswa hafu-upenyu venlafaxine ndiyo 11 uye 5 maawa ukuwo (goho mu kuchinja chimiro ne itsvo).

The kinetics zvinodhaka chaiyo zvekuchipatara ezvinhu

Drug "Velaksin" mirayiridzo kunodiwa kuverenga muna vanhu vane cirrhosis chiropa ane zvimwe kinetic zvinhu. ropa wevasungwa zvinodhaka yakawedzera Varwere izvi, uye ayo mwero excretion nekusiyana, ipfupi.

In zvakakomba renal insufficiency, renal kukundikana uye nepakati zvachose Clearance Efa uye venlafaxine ipfupi uye kubviswa hafu-upenyu nguva miforo.

Zvinofanira kucherechedzwa kuti munhui, uye makore murwere asingadi kukanganisa pharmacokinetics zvinodhaka pasi kukurukurwa.

zvairatidza kuti

Nei tichifanira kuva chishandiso akadai "Velaksin"? Kushandiswa kwezvinodhaka ichi kuratidzwa kuora mwoyo-siyana mavambo (nokuti kurapwa uye prophylaxis).

Kurambidzwa kugadzwa

Under chii ezvinhu havagoni kushandisa zvinodhaka "Velaksin"? Reviews wevarwere uye vanachiremba vanoti mushonga uyu contraindicated kugamuchira:

• apo kugamuchira Mao FIs ;
• kwazvo itsvo zvirwere;
• panguva vanofungidzirwa kana kusimbiswa pamuviri;
• mune chakakomba kusagadzikana chiropa;
• paanenge achiyamwa;
• mu kuyaruka uye pauduku, ndiko kuti, kusvikira zera ruzhinji;
• dzakakwirira aikanganiswa mushonga.

Uyezve, mushonga uyu anofanira kunyatsoongorora wabatwa kusagadzikana angina, myocardial infarction (kusanganisira achangobva vaitama), BP, kugwinha kare, tachycardia, uremu, ikawanda intraocular kumanikidzwa, angled-kuvhara yemaziso, kubatwa kuti ropa mucous uye ganda, inoti nemanic.

Drug "Velaksin" (Mahwendefa): mirayiridzo kushandiswa

Antidepressant "Velaksin" vanofanira chete kutorwa munguva kudya. Zvavakabvumirana pokutangira dose zvinodhaka pa75 MG, chakakamurwa muna 2 yakakamurwa mishonga (i.e., 37.5 MG kaviri pazuva), ose zuva.

Kana papera vhiki yokurapa, murwere nemamiriro asina akavandudzika, nezuva dose ichiwedzerwa 150 MG rimwe zuva, muna maviri chakakamurwa mishonga (i.e., 75 MG kaviri pazuva).

Kana murwere kunoda wakakwirira dose ane antidepressant (semuenzaniso, zvikuru mwoyo chirwere, kana zvimwe zvinhu zvinoda kurapa mira), ipapo mukoti rinogona kunan'anura 150 MG zvinodhaka muna 2 maawa, uye ipapo zvishoma nezvishoma nokuwedzera dose ne 75 MG (mazuva 2-3 papera) kuzadzisa zvinodiwa mugumisiro.

Maererano mirayiridzo, kufadza chipimo chemushonga "Velaksina" riri 375 MG pazuva. Awana zvinozoita, inogona zvishoma nezvishoma akatura kuna shoma padanho.

Kuitazve kudzivirira nokuchengetedza kurapa

Kutsigira vatarisire mari anogona kutora kubva mwedzi mitanhatu. Panyaya iyi, mishonga wakabatwa usingashandi mishonga.

In nyoro renal insufficiency kururamiswa dosing zvaiitwa kunodiwa. In yakafanana chirwere mwero dose yakarumbidza kudzika pedyo 25-50%. Zvinofanira kucherechedzwa kuti venlafaxine haafaniri kushandiswa zvikuru renal insufficiency, sezvo pasina ruzivo pamusoro vakachengeteka yokurapa zvakadaro zvevakomana, kwete.

Vanhu vari pasi hemodialysis, vanofanira kugamuchira 50% kubva zvatinosiita zuva chipimo chemushonga zvinodhaka pashure pachirongwa kumugumo.

For nyoro hepatic insufficiency kururamiswa dosing zvaiitwa chiri haamanikidzwi. Kana hosha mwero dose anofanira kuderedzwa 50%. Panyaya zvakakomba hepatic kukundikana, muchiitiko ichi kushandisa venlafaxine hakubvumidzwi.

In vakwegura, mushonga "Velaksin" inofanira kushandiswa nokungwarira zvikuru. Izvi imhaka ingangovapo kutyora neitsvo. The varwere vanofanira mishonga rakadzika kunobudirira dose. Panyaya iyi, murwere inofanira kuva pasi chenguva zvokurapa achitarisirwa.

kukanzura antidepressant

Panopera kugashira zvinodhaka inofanira kuonekwa kuderedza dose zvishoma nezvishoma (mukati pavhiki). Zvinonzi kunodiwa kuchengeta ezvinhu omurwere, kuitira kurerutsa ngozi nenjodzi chokuita abolition zvinodhaka.

The nguva inodiwa kuti rakakwana kumira mishonga, kunobva chipimo chemushonga, ya kurapa uye vanhu vanowanzosarudza.

nemishonga

Ndezvipi pasingadiwi zvinokonzerwa zvinodhaka kungaita kuti "Velaksin"? Testimonials vanoti kukura avo kana zvimwe yaivhuvhuta zviitiko zvinotevera kushandiswa chokushandisa ichi kunobva dose yakagamuchirwa.

Zvikuru kakawanda siyana akaratidza kunaka hunhu zvinosanganisira zvinotevera:

• BP, ungaderedza kudya, zviroto kanganisika, kupatira, kushaya hope, kuda kurutsa, Flushing ganda, chakamira pakunodengenyeka zvine, kurutsa, tsandanyama chinyamunhari chinorwadza, muromo yakaoma;
• zvisipo, hepatitis, uremu, tachycardia, hyponatremia, kusakendenga, postural hypotension, dzungu, nemanic maitiro, huta excitability, yawning, paresthesia, neuroleptic urwere, ndivete serotonergic urwere;
• wakawedzera tsandanyama matauriro, nezvipusha, dysuria, photosensitivity, Urinary chengetedzo, anorgasmia;
• ropa paganda, zvemamiriro ejaculation, menorrhagia, ungaderedza libido, vangadikitira;
• thrombocytopenia, pekugara nenyonganiso, erythema multiforme, mydriasis, Stevens - Johnson, ziso nenyonganiso, havachanyatsogoni kuravira, prolongation kuti ropa nguva, simba, ganda mapundu, kurukutika, anaphylactic siyana.

Zvinofanira kucherechedzwa kuti mushure chimbichimbi kushaya ari vaiona motokari kana kuderedza ayo chipimo chemushonga zvinokwanisika zvakadai divi siyana sezvo huta kushatirwa, kurukutika, manyoka, hope, kupinduka pinduka, nomusoro, paraesthesias, kuda kurutsa, hypomania, kurutsa, vangadikitira, neanorexia, kushaya hope, akaoma muromo, kufunganya, dzungu uye nekuvhiri- ngika. Kazhinji, Zviratidzo izvi ndiwo munyoro uye woenda pasina kurapwa.

kurumbidza

Tengesa kana antidepressants pasina mushonga? A pamazita mishonga izvi hazvisi guru chaizvo ( "Prozac", "Paxil", "Despres", "Azafen", "Persian", "amitriptyline"), uye zvinodhaka "Velaksin" haisi zvaisanganisira mariri. Utenge muna Pharmacies, iwe unogona bedzi chiremba mushonga.

Asati kutora mushonga uyu pasi review, kunyanya varwere zvokuora mwoyo, inofanira kukurukurwa refu ndingangokuvara kuzviuraya kuedza. Panyaya iyi, pakutanga zvinodhaka mishonga yakarumbidza zvokushandisa shoma dose uye pasi pedyo zvokurapa achitarisirwa.

Vanhu vane zvinyamusi panguva kurapwa pamwe antidepressants zvingamuka nemanic kana hypomanic mamiriro.

Varwere vanofanira kuva nechokwadi kuyambira kudiwa pakarepo kuona chiremba kana urticaria okunze, rashes kana neutachiona.

Vamwe varwere vari muitiro kugamuchira venlafaxine vakachengeta dose-zvaanoda kuwedzera BP.

Varwere vakwegura vanofanira akanyevera zvichibvira kutyorwa pfungwa mwero uye dzungu kukura.

Panguva pakurapa mari kusatora doro.

Antidepressant "Velaksin": Murwere uchapupu, chigadzirwa analogues

Chii vanhu vanoti mushonga uyu murwere? vatengi vakawanda yakashuma yokuwanda nemishonga kuti kuitika apo kutora mishonga iyi. Kakawanda mushonga uyu kunokonzera nenjodzi dzakadai hope, utera, kushaya hope, nezvipusha, zvemamiriro mafungiro, kuora mwoyo uye kuvhiringika. Uyezve, vamwe varwere vanoti Migumisiro izvi vanosara pashure pokupedza kurapwa. Uyewo, vanozvishandisa zhinji vanotsutsumwa pamusoro chitarisiko ucharwadziwa uye kutsamira.

Chii chinogona kutsiva antidepressant akadai "Velaksin"? Analogs zvinodhaka izvi kwete kuwanikwa drugstores zvose. Kazhinji, nyanzvi idzi zvinosanganisira zvinotevera: "Venlafaxine Sandoz", "Efevelon", "Alvent", "Nyuvelong", "Velafaks", "Dapfiks", "Voksemel", "Venlaksor", "Vensuert", "venlafaxine".