Creatinine - ndozvakajairwa muropa uye weti. The kunotoda kukosha mharidzo

Creatinine - mumwe mwero ropa kemisitiri uye urinalysis. In kurapwa kemesitiri zvikaonekwa kunyanya nokuda kuferefeta reabsorbtsionnoy filtration uye renal mabasa. Nokuti chiremba, creatinine, mwero nokuwedzera yake kana pathological kunonyatsoratidza. Asi ngatitangei kuongorora chii fuma iyi uye sei anogadzirwa muviri.

Of nemakemikari omuviri bhuku rinogona kuwanikwa kuti creatinine mumwe anonzi magumo-zvibereko muviri. Zvinonzi aumba kubva puroteni creatine kushumira simba mabviro tsandanyama. In tsandanyama creatine chinhu remubatanidzwa yainzi phosphocreatine. Tiine rutapudzo kuti tsandanyama creatine rinopa ayo simba, uye iye anotanga kusvika kwokupedzisira chigadzirwa - creatinine, mvura uye phosphorus pachiyero. Saka muviri anooneka creatinine. wevasungwa Its kunoenderana uwandu kwetsandanyama. Nokuda kwaizvozvi, ropa creatinine varume, mwero, ichava nguva dzose dzakakwirira kupfuura vakadzi.

Mugumo zvibereko nedanho mapuroteni muviri yabudiswa kuburikidza itsvo dziri weti. The glomerulus creatinine kubva ropa yakasvinwa uye wakapfuurira renal tubules. kureva, panguva dzose oparesheni itsvo yabviswa zvachose kubva mumuviri, izvozvo rinocheneswa kubva ropa. On ichi kunobva mamiriro ayo chimwe chezvinhu zvinokosha miedzo itsvo - Mharidzo Rehberg. Kurishandisa Akatsunga glomerular filtration. Uye nokuda known GFR dzaona renal tubular reabsorption. Asi regai nezvazvo pashure.

Creatinine ane wokuyera varume ndiwo 0,044-0,106 mmol / L, uye vakadzi - 0.44-0,88 mmol / L inowedzera kunyanya zvirwere itsvo. A Nhamba mumarabhoritari migumisiro pakudzidza vari anotaurwa nevamwe dzakabatana - mune micromoles. Kuisa mukati micromoles mmol creatinine nemifananidzo zvinofanira kane 1000. Somuenzaniso, mwero vanhu - 44-106 mmol / l.

Inosimudzira creatinine - mumwe chikuru zviratidzo itsvo kukundikana. Zviri nokuti kuti filtration iri renal glomeruli zvinoderedza zvinoshamisa kana renal maronda.

Zvisinei, renal zvokurwara - kwete chikonzero chete kuti zvibereko chinoratidza ichi. inoti zvose uye zvirwere iyo pane kukurumidza Kuparara phosphocreatine ari tsandanyama, anogonawo kusimudza creatinine muropa kuti dzakakwirira nhamba. Izvi zvinogona ine tsandanyama basa, hyperthyroidism, zvokudya akapfuma mapuroteni, kupera muviri, acromegaly.

Kana mamiriro ezvinhu nechokuita tsandanyama rinenge maronda, creatinine yakawedzera, zvakare. Somuenzaniso, zvakawanda myocardial infarction achiperekedzwa kwakawedzera creatinine. Radiation chirwere, kutsva, apwanye chirwere zvakare mberi nezvibereko zvayo.

Kutora mamwe mishonga anowedzera creatinine. wokuyera Its zvinogona kupfuura kana murwere anogamuchira sulfonamides, barbiturates, mishonga ine tetracycline uye aminoglycoside dzakatevedzana.

The kuderera creatinine kudzika pane dzose asina chirwere ukoshi, sezvo kuwedzera. Zvingava nokuda rwakakwana yaunodya mapuroteni zvokudya, nzara, vaneta. Ungaderedza creatinine rechitatu pamuviri, edema, ascites wokutanga. Zvinobatsira kuderedza creatinine mazhinji kushandiswa corticosteroids.

Nokuti vanofungidzirwa renal kukundikana, sezvo kare akataura, chinowanzoonekwa chinotarisirwa Reberga mharidzo.

Kana zvikaonekwa achiitisa creatinine, mwero izvo muropa renal kukundikana anogona zvikuru kupfuura uye weti creatinine. Weti yokuenzanisira Rehberg anofanira inounganidzwa masikati, rinopa mhinduro yakarurama pane kana inounganidzwa munguva shoma. Zvakakodzera zvakarurama kuyera inzwi rayo. Murabhoritari runopiwa shoma zuva weti vhoriyamu, zvose haina kubereka. Kana kunhonga weti vanofanira kudzivisa rinonetesa muviri uye kudya mapuroteni yakawandisa. Ropa usina chawadya mangwanani. The daily creatinine excretion ari weti chaiye vakaenzana 4,4-17,7 mmol / zuva.

Mushure Pakusarudza ropa uye weti creatinine, achiziva uwandu weti nezuva, uremu murwere uye kukwirira (ekupedzisira rinoshanda kunyanya vana) rinokosha murabhoritari inonyatsoita anoti ari glomerular filtration uye ipapo - tubular reabsorption. Standards nokuti repakati vakuru: glomerular filtration vanhu - 82-140 Rine mamiririta / Maminitsi, vakadzi - 81-128 Rine mamiririta / min. Norma tubular reabsorption - 95-99%. Kana zvaipesana renal basa, tsika idzi ipfupi.