Drug "Sibutin": mirayiridzo kushandiswa, tsananguro uye wongororo

Sei uye kana murwere ushandiswe mishonga "Sibutin"? Mirayiridzo yokushandisa, dzomuzana chaivo uye zvairatidza kuti kushandiswa akapa zvishoma mberi. Nyaya vakakurukura Kuronga chinodhaka, wawo uye kusunungurwa kurambidza kushandiswa.

Chimiro, tsananguro uye akafanana

Kugadzirira "Sibutin", mirayiridzo kushandiswa riri pasi apa, anogadzirwa muchimiro chena rwakapoteredza Mahwendefa vane chiratidzo rimwe divi. Ravo rinoita fuma iri oxybutynin (muchimiro oxybutynin hydrochloride). Uyewo medicament zvinosanganisira adjunct zvinhu, sezvo chiri muchimiro lactose monohydrate, microcrystalline cellulose, mbatatisi starch uye calcium yakawanda stearate.

Pharmacological ehupfumi zvinodhaka

Sei "Sibutin"? Mirayiridzo yokushandisa, vanachiremba chaivo dzinoshuma kuti mashandiro chiito zvinodhaka izvi zvachose nokuda kunyatsoshanda waro vanoshingaira zvinhu.

Maererano nenyanzvi, "Sibutin" inomirira blocker M-cholinergic receptors, kuva boka tertiary amines. Tichifunga M-mwero anticholinergic basa, nyaya mumiririri anokwanisa anokanganisa zvakananga anotsvedzerera tsandanyama pakati viscera. Panguva iyoyo rine antispasmodic uye myotropic chiito. Nemamwe mashoko, mushonga uyu anobvisa kurwadza kwacho, uye akazoita tsandanyama mataurire zvinotevera mitumbi: ari biliary turakiti, nemudumbu, Urinary turakiti, muchibereko chemusikana uye dundira. Zvinofanira kurangarirwa kuti vanhu vane neurogenic dysfunction rokupedzisira oxybutynin anokwanisa kwenyama detrusor, kuderedza ayo kwatangwa sunga, kuderedza kakawanda weti, uyewo kuwedzera inogona dundira.

Kinetics zvinodhaka

Raisangoita nomuromo kana nzira dzakadai se "Sibutin"? Mirayiridzo yokushandisa (chikamu zvinodhaka rakanga pamusoro apa) rinoshuma kuti pashure kushandiswa mahwendefa oxybutynin nokururamisira nokukurumidza woga kubva zvomudumbu turakiti.

Ongororo dzakaratidza kuti kufadza pfungwa yacho chinhu muropa riri pamusoro 8-13 Ng / Rine mamiririta. Nhamba iyi ndizvo kuti dosages ose 7-10 MG vakagamuchirwa muduku uye noutano vanhu. Uyewo, kwaiva kucherechedza mumwe kusiyana uwandu oxybutynin ari plasma.

Tichifunga ndima yokutanga kuburikidza chiropa, Mhedziso systemic bioavailability venhumbi anenge 6.2%.

The chikuru metabolite pamusoro oxybutynin rinoshanda desethyloxybutynin. Also akaumba kushandurwa kwacho, uye zvisinei, dzimwe nomukaka kusanganisira feniltsiklogeksiglikolevaya acid, ivo vakaneta.

About 0.02% vakagamuchira medicament iri kusunungurwa weti. Communication oxybutynin kuti sealbumin anenge 83-86%, uye nguva yaro hafu-upenyu maawa maviri.

Refu kushandisa mishonga kwayo kuwanda yakaderera.

Zvairatidza kuti kushandiswa kwezvinodhaka

Kana murwere anogona kupiwa "Sibutin"? Mirayiridzo dzokushandisa (zvairatidza ichakurukurwa pazasi), rinopa kuti mushonga zvinowanzodavirwa kushandiswa pakurapa Urinary incontinence nokuda kusagadzikana nokushanda dundira, yamakaramba neurogenic hunhu (semuenzaniso, detrusor hyperreflexia, chinonzi spina bifida kana nemultiple sclerosis) kana ane idiopathic hunhu.

Zvinofanira kucherechedzwa kuti nzira idzi kungaratidzwa kuti usiku enuresis mune vana vane makore makore mashanu. Nokuda kwaizvozvi medicament inoshandiswa monotherapy, uye akabatana nevamwe mishonga.

Inorambidza kushandisa mapiritsi

Kana asina raitongwa murwere mushonga "Sibutin"? Mirayiridzo Dzokushandisa rinoti contraindications kugamuchira mushonga uyu ndedzinotevera inoti:

• bowel mhingaidzo;
• Hypersensitivity kune zvinoreva zvinoriumba izvozvo;
• intestinal atony;
• vakaratidza zvinetso ironge chokubuda weti kubva dundira;
• myasthenia gravis;
• maronda colitis (kwazvo);
• pakuwedzera muura;
• pamuviri;
• yemaziso;
• achiyamwa;
• makore mashanu.

Drug "Sibutin": mirayiridzo kushandiswa

Mahwendefa "Sibutin" kunyanya kuzviita vakuru. Vanofanira kutora 5 MG katatu pazuva. Varwere vakwegura achishingaira zvinodhaka inokurudzirwa kushandisa imwe mari 5 MG kaviri pazuva.

In rinokosha kacho, mushonga uyu chinotarisirwa kuti vana pasi pemakore mashanu. In kutyora dundira neurogenic hunhu kushandiswa kwezvinodhaka nokuda 5 MG kaviri pazuva, uye usiku enuresis - 5 MG katatu pazuva. Panyaya iyi, wokupedzisira dose zvinofanira kutorwa pamberi yokurara.

nemishonga

Ndezvipi zvinoitwa zvakaipa hunhu iri mushonga "Sibutin"? Mirayiridzo dzokushandisa inoshuma kuti dzakawanda migumisiro izvi inomuka pamusoro chikamu zvomudumbu turakiti. Kazhinji, vanoonekwa yakaoma muromo, kupatira, kuda kurutsa, abdominal kusanzwa uye manyoka.

Uyewo vaiona mushonga anogona kukonzera:

• nemusoro, madzerere, hope, dilated vadzidzi, dzungu, vakawedzera intraocular kumanikidzwa;
• ganda rakaoma;
• Maze (kuitika kunyanya vana), Urinary chengetedzo, achinetseka vanhurume, arrhythmia, akaderedza ziya.

zviitiko ovhadhozi

Chii zviratidzo kuitika apo zvinodhaka ovhadhozi "Sibutin"? Instructions ari kushanda rinoti kuti kuratidzwa dzakadaro inosanganisira zvinotevera: kufunganya, vakawedzera kwokuomerwa nenjodzi, nokusagadzikana, kufema uye kweropa kukundikana, pasi BP, psychosis, pakoma kuoma kufema tsandanyama.

Nokuti kurapa mamiriro ezvinhu akadaro anoshanda gastric lavage, uyewo intravenous kwokubatsira physostigmine.

Kana akaratidza excitation kana kufunganya varwere raitongwa "Diazepam" (w / W, 10 MG) mu fivha symptomatic kurapa, tachycardia inoratidza kugadzirira "propranolol" (w / W) pamwe Urinary chengetedzo akaita catheterization pamusoro dundira, kana kuoma kufema tsandanyama uye kubudirira kurarepodobnymi mugumisiro zvinopa kufefetedza.

Sei interacts nedzimwe zvinodhaka?

Ndinogona kushandisa dzimwe nzira kugadzirira "Sibutin"? Mirayiridzo kushandiswa kutaura, iyo kana kubatanidzwa nemamwe zvinodhaka vaitirei mushonga kungaita wakawedzera divi zvavaifunga. Kazhinji, zvakadaro zvakaitika rinozivikanwa apo pakugamuchira "Sibutina" pamwe nevasori kuti vane anticholinergic chiito.

Kunyaradza zvinodhaka uye panyaya iyi inogona kubatsira dzungu uye hope kuatsanangura.

Pamwechete kubvuma "itraconazole" oxybutynin kunowedzera wevasungwa muropa.

panguva pamuviri

Zvinoita panguva mwana vakamirira kushandisa mishonga iri mubvunzo? Safety pakushandisa "Sibutina" haina dzakatangwa panguva iyi. Saka, chikamu ichi wevarwere, akati kunoreva harigadzwi. Zvinofanira kucherechedzwa kuti oxybutynin anogona kuyambukira mukaka, saka hazvifaniri kushandiswa panguva lactation. Kana zvichiri zvakakodzera, achiyamwa zvinofanira vakarega.

chaicho mashoko

Zvaunofanira kuziva murwere vasati uchishandisa mushonga "Sibutin"? Mirayiridzo dzokushandisa (analogues dziri pazasi) rinoti nokungwarira zvakanyanyisa mushonga anofanira kuzviita varwere vakwegura zvakanaka, uye varwere kwazvo nourwere etsvo uye chiropa uye neuro dystonia.

Kungofanana nevamwe anticholinergics, ari kushanda "Sibutina" vanoyambira vanhu vane heniya diaphragm (esophageal aperture), iro rinoteverwa reflux esophagitis.

Tikafunga zvinodhaka ichi kungawedzera murwere zvekuchipatara kuratidzwa arrhythmias, hyperthyroidism, prostatic hypertrophy, coronary tsinga chirwere uye mwoyo nokukundikana, chirwere hunhu.

Inosimudzira ambient tembiricha kana uchishandisa mushonga anogona kunyengedza nefivha uye kusagadzikana mwoyo (zvichiguma mukuderedza ziya).

Vanhu vari kuita basa ngozi, rinoda vainyatsotarisirwa uye kumhanya kuita, zvakakosha kuti anyevere kuti nyaya zvinodhaka kungaita madzerere uye hope.

Reviews uye analogues

Analogues zvinodhaka pasi pakudzokorora ndeinotevera: "Vesicare," "Detruzitol", "Dream Apo", "Spazmeks", "Driptan", "Zevesin", "Uroholum", "Urotol" uye vamwe.

Reviews pamusoro medicament ichi kunogona kusangana yakawanda. Vamwe varwere vakanga inogutswa kubudirira mishonga. Ivo vanoti mushonga unobatsira kudzora weti, kusanganisira usiku. Zvisinei, vanhu vakawanda vanotsutsumwa pamusoro kukura nomusoro uye nezvimwe zvinhu uye dzimwe nenjodzi. Panyaya iyi, vanofanira kutsiva zvinoreva akachengeteka analogues.