"Izoket" mwaya: mirayiridzo manual, ongororo, rondedzero, analogues, mutengo

Nhasi, nyanzvi dzakawanda akarayira varwere vasodilator mwaya "Izoket" prophylactically kana, kana zvakakodzera, cupping nokurova. The mushonga une zvakadzama mazita zvinoratidza siyana. Zvinonzi zvinobudirira kushandiswa pakurapa zvemwoyo pathologies, kusanganisira kuti tikurire chakasimba ezvinhu.

pharmacology

Active mutumwa mushonga kubva angina pectoris dzinoratidzwa raidudzwa vasodilating uye vasodilator zvivako. Isosorbide dinitrate zvinosimudzira paumbwe senitrogen oxide ari Muviri anoderedza zvinodiwa pomwoyo reokisijeni uye simba, nokudaro achidzikisa mutoro pamusoro myocardium. It zvinobudirira kunoderedza kumanikidzwa iri pulmonary riparadzirwe, zvinoderedza ropa riyerere kurudyi atrium, kunoderedza cardiac ventricular rusvingo makakatanwa uye kuderedza diastolic kumanikidzwa uye systolic basa iri nani kwavari. The mushonga hakuna zvainoita kakawanda sunga zvomwoyo uye kunosvika tsime chepfungwa midziyo. Kunogona kuwedzera ropa midziyo reDhura mai uropi uye pakudaro nokuwondisa ari musoro. Achishandisa simba pamusoro redistribution rimwe coronary ropa riyerere munharaunda apo ropa chokubuda ipfupi. In CHD (nechirwere chemwoyo) uye angina nokuda Zvakaitwa mushonga pavarwere vane mukana kuwedzera bvumidzwa muviri.

Mwaya "Izoket" nokukurumidza woga mhiri mucosa muromo nzvimbo, saka nezvaizoitwa chikumbiro chacho chinotanga pashure masekondi 30 uye kunotora kuti maminitsi 120. Nemhaka pakukurumidza chinowanzoonekwa ushandiswe varwere kuti nokukurumidza kuti rikwanise ezvinhu.

kusunungurwa Form

The mushonga iri mhinduro yakajeka, iri Hauoneki uye ane chidhakwa kwakanaka. Anouya mhando mbiri:

1. Mwaya "Izoket" uye sublingual chipimo chemushonga. With imwe watinya pamusoro dispenser ukasunungurwa muchimiro duku samadonhwe imwe yayo dose iro rinoumbwa 1.25 MG ose vanoshingaira chirungiso - isosorbide dinitrate uye ebetsero zvinhu: panyaya iyi uye Macrogol 400. The aerosol sezvamunoita une freon, zvisinei kwazvinoita zvinodhaka sakuvadza nokuti zvakatipoteredza. Achibudiswa njenjemera hombodo dzemvura 15., dzaizara mubhokisi ane dispenser nemirayiridzo. Glass bhodhoro 300 the clicks (mishonga), kunoita kuti kuongorora uwandu zvinodhaka uye kuwana mumwe munhu wokutsiva mune nenguva nenzira.
2. The Kugadzirisa mu Kuisa pfungwa pachinhu chimwe chimiro dzaizopiwa infusions. 1 ml gadziriro ino ine 1 MG yezviri vanzwe isosorbide dinitrate uye ebetsero zvinhu: yavaibvisa chloride, yavaibvisa hydroxide, mvura. Mumwe chinu - 10 ml mhinduro kuti aizomupa. Rinowanikwa kabhodhi packs it 10 zvidimbu nerimwe.

zvairatidza

Mwaya "Izoket" nyanzvi vakagadzwa panguva stenokardicheskie kurwiswa kwose uye kuzvidzivirira chipimo kuzvidzivisa. Zvinonzi zvakare pachii post-infarction rinoti, myocardial infarction iri rikwanise danho, kuwedzera kushivirira pamwe IMS uye kurapa pane coronary tsinga spasm. Aerosol "Izoket" vakabudirira kushandiswa mushonga kuti mwoyo kukundikana ventricle kuruboshwe. Maererano mirayiridzo, funga kuti aizomupa iri ushandiswe varwere vane pathologies pakati kumwoyo kwakadaro:

• kusagadzikana angina zvichiitika preinfarction ezvinhu kana yapfuura myocardial infarction;
• vasospastic angina;
• myocardial infarction ari rikwanise chimiro, kunokonzerwa kukundikana rworuboshwe ventricle mumoyo;
• coronary vasospasm panguva zvomusejari kupindira;
• mwoyo kutadza kwose;
• chenjera kuruboshwe ventricular mwoyo kutadza;
• pulmonary edema.

Nzira kushandiswa aerosol

A gadziriro iri muchimiro pfapfaidzo sprayed kupinda waiita mhango murwere, nokuda ichi rakakurumidza anopinda ropa rukova. Mumwe jekiseni anopa mumwe ingestion dose. Mirayiridzo dzokushandisa rinoreva nzira dzakasiyana-siyana kushandisa zvinodhaka, zvichienderana zviratidzo.

Kuitira cupping stenokardicheskie kurwisa pamberi kuuya chaiko kana mupfungwa anogona kukonzera chakasimba, kunonoka afemeruke, uye murwere anogamuchira kubva 1 kusvika 3 mishonga pane zvikamu mumasekonzi 30 pakati majekiseni. Kuwedzera uwandu husingakuvadzi pasina cherechedzo nyanzvi wairambidza.

Kana vakafunga exacerbation mwoyo nokukundikana kana myocardial infarction, chenjera pamusoro murwere anogamuchira kubva 1 kusvika 3 mishonga pasi zvachose kudzora zvose kwemwoyo uye kufamba kweropa. Kana pasina kuvandudzika, ipapo nzira inodzokororwa maminitsi mashanu gare gare zvasarudzwa nachiremba. Munyaya inotevera maminitsi gumi, mamiriro ezvinhu anofanira dzikamisa. Zvikasadaro, unogona kudzokorora kuchinja kamwe zvakare pasi pokudzora chiremba.

Asati kurapwa nzira cupping coronary spasm (nokuti chirwere kana kuti yokurapwa catheterization) raitongwa murwere nokuda jekiseni 1-2. Pakamuka kudiwa chipimo chemushonga inogona kudzokororwa, asi kana kudzora parameters ropa kutenderera chete.

Dzinenge kurumbidza kuti kushandisa pfapfaidzo

Muzviitiko kana pfapfaidzo itsva rinoshandisirwa kekutanga, kana pashure rokupedzisira dose kwave maawa anopfuura 24, zvinokurudzirwa kutungamirira venhau wokutanga mudenga, nokuti haigoni zvine runodiwa chipimo chemushonga. For mishonga maererano nemirayiridzo nebulizer nguva dzose aimanikidzwa kumugumo, uye ndokusunungurwa. Panguva kushandiswa ane pfapfaidzo bhodhoro dispenser zvinofanira upwardly uye vertically. Shandisa Yambiro uye torega richierera kupinda maziso. Munguva yose kurapwa nguva kunoda kuramba kudzora BP (BP) uye ECG kunhaka. Kukosha kweropa hakufaniri asingasviki 100 mm HG. Art. Chimbichimbi kurega zvinodhaka akarambidzwa mirayiridzo, saka dose yakatarwa shoma zvishoma nezvishoma. Doro zvisina varumbidzwa vachitsigira aerosol "Izoket".

Reviews nenyanzvi inoratidza kuti dzakakwirira chipimo chemushonga kurapwa, kazhinji kugadzwa kana hurongwa kushandiswa kungaita kuti kushivirira kukura mune murwere. Akadaro chinhu kunokudziridzwa uye kushandisa zvimwe zvinodhaka kuti akaumbwa nitrates. Muzviitiko zvakadaro, vanachiremba vanoti kudzima kushandiswa kwezvinodhaka mazuva 2-3, uye pashure nzira dzose kurapwa, urwo rwakatora mavhiki 3-6, tora kuregawo kwemazuva 3-5, uye kuritsiva kwekanguva vamwe zvinodhaka zvakafanana migumisiro. Kazhinji, pashure ane chidzivaidzo kana discontinuation aikanganiswa murwere asi nokukurumidza rakadzorerwa. zvinoreva zvinoriumba hwokurara metabolites sapamakore neitsvo anenge azere.

Chipimo chemushonga uye kushandisa mhinduro

Maererano nezvinodiwa pakuranga gadziriro "Izoket" (nokuti aizomupa mhinduro) rikashandiswa nomutsinga. The chipimo chemushonga of kurapa vrechom nomumwe yakadekara kuti hemodynamic uye kurapwa parameters zvomurwere. Zvipatara vanofanira kutanga pasi dose uye kuwedzera zvishoma nezvishoma kuunza runodiwa uwandu. Instructions vanorumbidzwa chipimo chemushonga ndiyo 2-7 MG / hr ukuwo, avhareji dose anenge 7.5 MG / hr. Muzviitiko zvokuora kunofanirawo inzwi kunogona ngazviwedzerwe 10 MG / hr.

Kazhinji, vanhu vane mwoyo nokukundikana zvinoda yepamusoro mishonga yacho zvinodhaka. Musumo zvinodhaka vanofanira kumbotambudzika inpatient kurapwa pasi pokudzora nyanzvi uye kushandisa otomatiki enyika kuti aizomupa. The yose nzira iri pamwe kudzora zviratidzi kuparadzirwa (BP uye kwemwoyo).

A mhinduro intravenous Kutarisirwa rakagadzirwa mu chena ezvinhu pakarepo pamberi nzira. The mushonga hauna kuchengetwa maawa anopfuura 24. gadziriro nzira:

• kune wevasungwa pakati 0.01% (100 micrograms / Rine mamiririta) - 50 ml 0.1% zvinodhaka kungaita kuti 500 ml kugadzirira vakagadzirira vaitarira;
• kune wevasungwa pakati 0.02% (200 micrograms / Rine mamiririta) - 100 ml 0.1% mhinduro yacho zvinodhaka kungaita 500 ml ari medicament takagadzirira kutarisira.

Contraindications uye matanho

The mushonga hakuratidzwi varwere hypersensitive kune nitrate yeimwe, uyewo mamwe masangano ari aerosol "Izoket". Chikumbiro iri wairambidza kana murwere zvirwere zvakadai:

• hypotonia, panguva iyo systolic kumanikidzwa riri pazasi 90 mm HG.
• vascular insufficiency iri rikwanise danho, semuenzaniso, mumakore kuvhunduka kana vascular dhirika;
• pericarditis uye pericardial tamponade;
• mune cardiogenic kuvhunduka muzviitiko apo pasina mukana kuchinja mumwe nzira nevamwe rworuboshwe ventricle mumoyo;
• hypertrophic cardiomyopathy;
• kuvhara yemaziso.

Mukuwedzera, mushonga hakuratidzwi vanhu pasi gumi nemasere ekuberekwa. Mirayiridzo yokushandisa anokurudzira kushandisa zvinodhaka nokungwarira akanyanyisa uye pasi kugara achitarisirwa Muzviitiko zvakadaro:

• myocardial infarction pamwe rikwanise aibuda kana murwere ane akaderedza kumanikidzwa akasiya mwoyo ventricle zvekupfakira;
• rikakura intracranial kumanikidzwa;
• mitral uye / kana kutsemuka stenosis;
• Detective kuwanikwa mukana murwere orthostatic nepfungwa iri murau ropa kutenderera;
• renal kana chiropa kukundikana.

Pregnancy uye lactation

Masayendisiti kukura zvidzidzo zvinodhaka mhuka yave ichiitwa. Kuedza pamusoro bvunzo kwakaratidza kuti zvikuvadze fetus haana akaita. Zvisinei, panguva yepamuviri uye lactation nguva kugadzwa ane aerosol inokurudzirwa chete avo ezvinhu apo aida kubatsirwa kuti vakadzi achava yekudyidzana kupfuura zvingakanganisa azvarwa kana zamu-mwana. Treatment Muzviitiko izvi zvinofanira kuva pasi kuzviomesera pokudzora nyanzvi, kuparadzirwa kuzvidzora parameters (BP uye mwoyo urove zvazvingava), uyewo mukuru ezvinhu omurwere.

Kudyidzana nevamwe zvinodhaka

Zvinonzi rambidzwa kugoverana vasodilators uye "Izoket" gadziriro (pfapfaidzo). kushandiswa kwavo yakasanganiswa kungaita akawedzera hypotensive kushanda. Zvimwechetezvo rinobatanidza mawa kugamuchira "Izoket" nemishonga aerosol akadai: antihypertensives, karusiyamu gwara blockers, "Quinidine" kana "novokainamid" neuroleptics, 5-phosphodiesterase FIs.

Kuwedzera antianginal zvazviri kana kushandiswa pachiimbwa zvinodhaka akadai "Amiodarone", "propranolol", "Nifedipine", "Verapamil," uye nedzimwe blockers ari karusiyamu kunonoka gwara.

Yakawedzera intracranial nevamwe murwere anogona kuitika panguva mubatanidzwa kurapa pamwe atropine uye nemamwe mamita-holinoblokatorami.

Kunwisa kuderera BP, zvichitungamirira coronary perfusion, rinowanika achifuridzirwa Arifa-blockers uye sympathomimetic.

Marwadzo uye wongororo

Mirayiridzo anorondedzerwa zvakawanda nemishonga kuti anogona kukonzerwa zvinodhaka "Izoket" (pfapfaidzo). Reviews vamwe varwere kubatwa zvinodhaka ichi, anoratidza chimiro musoro, izvo mushonga unonzi "nitrates". Kazhinji, pashure pemazuva 2-3 dambudziko haazombotaurwi pamusoro yayo uye haatarisiri kururamiswa. Asi kashoma medicament kungaita mananara akadai kuda kurutsa, akatsvuka ganda, kurutsa, uye muromo yakaoma. Vamwe varwere vakagamuchira mishonga kokutanga, vachinyunyuta pamusoro vakawanda simba, dzungu, kunoderedza BP uye kunzwa lethargy. Izvi zviri kukonzerwa vachivavhiringidza duku kushanda kumwoyo. Ivo simuka paaishandisa chikuru kana vakapfuura zvavakabvumirana chipimo chemushonga.

Zvisinei, maererano wongororo, varwere cherechedzai uye efficacy. Uye kana kugamuchira maererano nenyanzvi zvinodiwa nemishonga regai kuitika kudaro kakawanda. Kusara ndiyo nomusoro mumazuva kushandiswa, iyo kuitwawo Kakawanda kacho wokutanga, asi kazhinji inopfuura mumazuva mashomanana.

Kwazvo kufadza vhoriyamu

An ovhadhozi zvinodhaka kungaita zvinoverengeka zvakakomba zvarakasiya: syncope, pakaparara, yakakwirira intracranial kumanikidzwa, hyperthermia, nezvipusha, kutarisana basa zvirwere, rakawedzera vangadikitira, methemoglobinemia, bradycardia, muviri, uye pakoma. Ndokusaka zvichikosha kwete kuzvicheka-mwoyo, uye kutora zvinodhaka zvakasimba maererano zvinodiwa nyanzvi!

Kana zviratidzo zvakatsanangurwa kunoda nokubviswa husaberekana uye kuitisa zvainanga pakudzikamisa murwere ezvinhu.

analogs

Medicament "Kardiket» (CHWARZ PHARMA, Germany) - mumwe rakajairika Generic zvinodhaka (analogs) zvinodhaka "Izoket" (pfapfaidzo). Mutengo chinotsiva iri novimba wevasungwa yezviri fuma uye uwandu mapiritsi ari pasuru.

Somuenzaniso, mutumwa pamahwandefa 20 MG "Kardiket kutadzisa" (20 hrs. On the pasuru) anobva 62 kusvika 72 rubles, apo imwe gadziriro, chete panguva imwe chipimo chemushonga 40 Mahwendefa MG uye nhamba yemabhuku zvidimbu 50, ane ukoshi 210-220 rubles.

Boka mishonga "Nitrosorbid" kugadzirwa nemakambani akawanda Russian, uye kuva siyana yaakazosunungurwa, zvakare, ndiyo womutariri chinodhaka "Izoket". Analogues veboka iri vane zita "Nitrosorbide-Rusfar", "Nitrosorbide", "Nitrosorbide NS", "Nitrosorbide-UWI."

mari

In Pharmacies Russian achava kuripira kubva 365 kusvika 470 rubles muzana chipimo chemushonga idzidziso "Izoket" (pfapfaidzo). Mutengo aumbwa zvichienderana nzvimbo chitoro nzira yokubudisa uye ayo mamiriro. On Websites kuti kutengesa mushonga inogona kutengwa mari yakaderera pane imwe kwakajairika chemishonga pedyo nomusha wako. Asi kana achirayira pamusoro Internet vachafanira kubhadhara 200 rubles pakukurukura kana kugamuchira akasununguka mumiririri mundima ex, iyo nguva iri pedyo munharaunda yakakura.

Uyewo, chero chemishonga unogona kutenga pasuru (10 ndiro) pfungwa mhinduro kuti aizomupa "Izoket". mutengo wayo zvichisiyana 906-980 rubles.

tsananguro

The mushonga iri kugadzirwa ne kambani German "YUSB Pharma GmbH". The pasherefu upenyu kwemakore mashanu. Terms waakazvitengesa - kuvapo yachiremba mushonga. Pashure kwenguva mashandisiro Zvinokurudzirwa kuongorora mabasa ari sprayer. Chikwata of aerosol wavhomorwa kubva pasi museve. Kana mvura zvasvika padanho kunofanira kuva kuwana mushonga mutsva, kubva pakushandisa kumbova Bhodhoro ndiyo chete zvinogoneka zvishoma tilted, umo rwomwana chubhu iri achinyatsotaurira nemvura.