"Kaffetin Cold": mirayiridzo yekushandiswa, kuumbwa, zvakafanana

Chii chinonzi "Kaffetin Cold"? Kuumbwa uye maitiro echirwere ichi zvichakurukurwa pasi apa. Uyezve, tichakuudza nezvekutora mishonga iyi uye pasi pezvirwere zvinorayirwa.

Fomu, kugovera, kuumbwa

Mushonga we "Kaffetin Cold" unoenderera mberi uchitengeswa nenzira yehwendefa oblong uye biconcave fomu (ine ngozi kune rumwe rutivi), yakafukidzwa nepepuru yemafirimu shell. Izvo zvinenge zvichisimudzirwa mubheji rinoputika, rakagadzirwa nea aluminium foil uye yepafirimu yakaturikidza yakareba, iyo iri mubhodhi bhodhi.

Chii chinonzi mishonga se "Kaffetin Cold" ine? Kuumbwa kwemishonga iyi ndeyotevera:

• Hydrobromide dextromethorphan (15 mg);
• Pseudoephedrine hydrochloride (30 mg);
• Ascorbic acid (60-62 mg) muchimiro chegranulate ine 97% ye vitamini C uye 3% ye hydroxypropylmethylcellulose;
• Paracetamol (500-555 mg) muchimiro chegranules, 90% inosanganisira dutu, uyewo masangano anobatsira nenzira yegelatinized starch, stearic acid uye povidone.

Inofanirawo kucherechedza kuti "Kaffetin Cold" sezvimwe zvinosanganisa zvinosanganisira magnesium stearate, colloidal silicon dioxide , microcellulose, croscarmellose sodium uye talc.

Iyo michina yefirimu yemudhaka iyi inoumbwa nebhuruu dye, macrogol, titanium dioxide, polyvinyl alcohol uye talc.

Pharmacology yezvinodhaka

Ndezvipi zvinhu zvinowanikwa pamapiritsi "Kaffetin Cold"? Iyo murayiridzo inopupurira kuti uyu mujeri anokwanisa kuratidza antisgesic uye antitussive.

Iyo nzira yekuita kwechirwere ichi inokonzerwa nekuvapo mairi kwezvikamu zvinotevera. Ngationgororei zvavanoita iye zvino:

• Paracetamol inoshanda pamuviri anesthetizing uye antipyretic. Ichi chinhu chinokwanisa kudzivisa COX mumutambo wepamusoro wenheyo. Izvi zvinoitika kuburikidza nekukanganisa zvakananga pane nzvimbo dzekutambudzika uye kupisa.

Chimwe chinhu chakasiyana neizvi chinobva kuNSAID ndechokusavapo kwakakwana kwekunopesana-kupisa simba. Paracetamol haiti kutsamwisa mucosa yemakumbo emimba, uye haibatsiri mvura yemunyu inonzi metabolism, sezvo inenge isisina kuipa kwekushandiswa kweprostaglandin mumakumbo emakumbo.

• Ndezvipi zvakare zvinoshamisa nezvechirwere "Kaffetin Cold"? Kuwedzerwa kwepseudoephedrine kunogona kuita kuti kuderedza mitsara iri mu mucosa ye pharynx uye musal cavity. Uyewo, chinhu ichi chinonyanya kuderedza edema, nokudaro kuderedza secretion mu nasopharynx nekuita kuti kufema kufema.
• Ascorbic acid, iri mune mishonga iyi, inobatsira kudzorera kusakwana kwevhitamini C, iyo inowanzoonekwa panguva yechando.
• Dextromethorphan ine zvakagadziriswa pachikwata chekukandira. Iyo inoderedza kuoma kwekukanda kuoma, iyo inosanganiswa nekutsamwa kwemukatious nasopharynx kune festi.

Properties kinetic

Kubata kwechirwere "Kaffetin Cold" kunoitika sei? Mhinduro dzevaongorori dzinoratidza kuti kunyanya kwepacetamol kunowanikwa mudumbu duku. Panguva imwecheteyo, kukwirira kwayo kwakanyanya muropa remvura kunowanikwa mukati memaminitsi 30-90 mushure mokutaurirwa nemuromo.

Metabolism yechinhu chiri mubvunzo (anenge 90-95%) inoitika pachiropa. Somugumisiro, zvigadzirwa zvisingabatsiri zvinoumbwa (zvichienderana nekugadzirisa kugadziriswa ne glucuronic acid uye sulfates). Zvinogona kuva nechinetso chekudzivirira pachiropa chekunyengedzera, pamwe nekukonzera kufa kwemasero avo.

Iyo hafu-hupenyu hwechikamu chino kubva mumuviri womunhu ndeyeawa maawa mana. Paracetamol uye metabolite yayo inonyadziswa neitsvo. Mukukwegura, pangave nekuderera kwekusununguka kwemishonga, pamwe nekuwedzera kwehafu yeupenyu.

Mushure mokunge dextromethorphan yakapinda mumuviri womunhu, inenge yava kunopinda muropa. Nzvimbo yakakwirira yezvinhu izvi mu plasma inocherechedzwa maminitsi 130 mushure mokutora mahwendefa. Ichi chinhu chinokonzerwa nemagetsi muropa. Izvozvo zvinonzi metabolite zvakanyonganiswa pamwechete nemuviri.

Pseudoephedrine inokurumidzawo kupinda mumashandisirwo e systemic mushure mokutaurira komuromo. Iyo yakanyanyogadziriswa yechinhu ichi mu plasma inowanikwa munenge maawa maviri. Ihafu-hupenyu hwepseudoephedrine inenge maawa matanhatu. Inoshandiswa muropa pachiropa (zvishoma), zvichiita pakuumbwa kwechigadziro chinowanzobudiswa kubva mumuviri pamwechete nemuyo.

Nezve ascorbic acid, inowanikwawo kubva pamagetsi uye ichikurumidza kugoverwa kune zvese zvinyuchi. Ichi chikamu chinonzi reversibly chinokonzerwa ne dehydroxyascorbic acid. Panguva imwecheteyo, imwe chikamu chevitamini C, iyo yakapinda mumuviri, inoshandiswa muitiro inonzi ascorbate-2-sulfate.

Ichi chinhu chakasununguka kubva mumuviri nemuyo.

Zviratidzo

Mushonga we "Kaffetin Cold" unoshandiswa mukuratidza zvirwere zvehutano nehutonho, kusanganisira kana pane zviratidzo zvisingafadzi zvakadai semusoro, kuomeswa kwakakomba, kurwadziwa kwemisvo, maronda, chirwere chemvura, fever, nasal congestion uye kusangana kwemazamu .

Contraindications

Mushonga we "Kaffetin Cold" haugoni kupiwa kuvarwere pasi pemamiriro ezvinhu anotevera:

• Kuberekwa;
• Hypersensitivity kumushonga;
• Congenital kukwana kweglucose-6-phosphate dehydrogenase;
• Arterial hypertension, coronary artery disease, angina pectoris;
• Kuputsika kwakanyanya mubasa reitsvo uye chiropa, hepatitis;
• Kushandiswa panguva imwechete yezvinorwisa antidipressants, monoamine oxidase inhibitors nemishonga inoshandiswa mukurapa antiparkinsonian;
• Lactation;
• Iva nemakore kusvika 12.

Nekuchenjerera, mushonga uyu unorayirwa kuti:

• Arrhythmias;
• Hyperbilirubinemia of benign;
• Hyperthyroidism;
• Viral hepatitis;
• Hyperplasia ye prostate gland;
• Kunwa doro;
• Chirwere cheshuga cheshuga;
• Kuvhara chirwere chepammonary chechirwere chisingaperi;
• Asthma bronchial;
• Kuneta.

Mishonga "Kaffetin Cold": mirayiridzo yekushandiswa

Ichi chinodhaka chinogadzirirwa kunyatsotungamirwa chete.

Nhamba yemishonga yevanhu vakuru nevechiri kuyaruka kubva kumakore gumi nemaviri yakaenzana nehwendefa rimwe kana kane pazuva. Pane imwe nguva, mapiritsi asingapfuuri 2 anobvumidzwa.

Nguva yenguva pakati pekushandisa kwemishonga inofanirwa kunge isingasviki maawa mana. Munyaya iyi, kuwedzerwa kwezuva nezuva kwechirwere hakufaniri kudarika mapiritsi 8.

Kana kukwirira kwemuviri wepamusoro kuchicherechedza mazuva anopfuura matatu kubva pakutanga kwerapi, uye kuomeswa kwakanyanya hakuperi kwemazuva mashanu, uye pakarepo ngotsvaka rubatsiro rwechiremba.

Dzimwe nguva zviitiko

Kukanganisa kwakashata mushure mokutora mishonga mumubvunzo kunogona kuzviratidza nenzira dzakasiyana, kubva kune nhengo dzose nemitemo yemuviri:

• Nausea, yakaoma muromo, kurwadziwa kwepigastric;
• Kutsiva, kutsamwa, kusagadzikana, chizuru;
• Kurwisana nehutachiona hwemuvara weganda, kuputika kweganda, angioedema, mikoko;
• Kuwedzerwa kweropa, kufambisa tachycardia;
• Anemia, thrombocytopenia, agranulocytosis, pancytopenia;
• Nephrotoxic effect, iyo inoratidzwa neRoal colic, kukura kwepapillary necrosis kana interstitial nephritis.

Overdose yemishonga

Paunenge uchitora mishonga yakakosha yemishonga, murwere anogona kuve nekurwadziwa, kuchera munzeve uye kurwadziwa mukati mudumbu. Uyewo, kana muyero wacho wapfuura, ganda remuurwere rinova rakanyarara, kutuka kwake kunowedzera uye mwoyo wake unowedzera.

Mhosva dzinotsanangurwa dzinoda kushambidzwa nokukurumidza kwemuviri. Uyewo, murwere anopiwa chirwere chekabhoni yakagadzikana inofanirwa nekurema kwemu murwere. Kana zvichidikanwa, chirwere chechiratidzo chinoitwa.

Kubatana

Kushandiswa kweparacetamol mumatokisi makuru kunowedzera simba reanticoagulants.

Kushandiswa kwemishonga inobatanidza kune inducers ye microsomal oxidation (p., Phenytoin, ethanol, barbiturates, Rifampicin, Phenylbutazone, tricyclic antidepressants), uye hepatotoxic vashandi zvinowedzera kuumbwa kwemashandiro anoshandiswa emagetsi emagetsi eparacetamol, izvo zvinowedzera mukana wekuwedzera kudhakwa kwakanyanya , Kubatanidza kana kutora madhii maduku emishonga.

Kushandiswa kwemazuva akawanda kwenguva refu kunoderedza kubudirira kweparacetamol.

Kubatanidzwa kweparacetamol uye salicylates kunowedzera mukana wekuve nekenza yemukaka kana yepfungwa.

Kushandiswa kwenguva refu kweNSAIDs uye paracetamol kunosimudzira kuonekwa kweanalgesic nephropathy, papillary renal necrosis, uyewo inonyanya kufanana nechigadziko chekuguma kusakundikana.

Kushandiswa kwe "Diflunisal" kunotungamirira kuchirwere chehepatotoxic chechirwere.

Kushandiswa kwakafanana kwepseudoephedrin uye mamwe sympathomimetic mazhenesheni kunogona kuita kuti zviitiko zvinosvibisa zviitike, uyewo kuwedzerwa migumisiro. Kubatanidzwa kwechikamu ichi ne monoamine oxidase inhibitors kunowanzoita kuti kukurudzirwa kwematambudziko eropa. Panyaya iyi, kushandiswa kwemishonga iri mubvunzo hakubvumirwi zvakare mberi kwemazuva gumi nemashure mushure mekushandiswa kwemonoamine oxidase inhibitor kwave kuregererwa.

Kushandiswa kwakafanana kwe "Propranolol" kunowedzera mhepo inopinza, iyo inoshanduka kuva pseudoephedrine. Mukuwedzera, nekushandiswa kwekupedzisira, iyo hypotensive effect yevakadaro se "Methyldopa", "Reserpine", "Mekamilamin" nezvimwe zvakadaro zvinogona kuderera.

Mashoko Akanangana

Iye zvino unoziva kuti chirwere chakadai se "Kaffetin Cold" ndechei.

Pervitine is methamphetamine. Iye ari psychostimulant uye anokonzera kukudzwa kwakakwirira, maererano nechinonzi chinonzi narcotic substances. Vamwe vanhu vanoedza kubvisa ichi chikamu kubva pamishonga "Kaffetin Cold". Mishonga inonyadziswa munzira dzakawanda. Kugamuchirwa kwaro kunokonzera euphoria uye panguva imwechete kunokanganisa zvirongwa zvose uye nhengo dzevanhu.

Mukurapa kwekurapa, mushonga uri pasi pekufungidzirwa unofanirwa kuchenjerera kushanda kwehutano hwechiropa chevarwere, uyewo zviratidzo zvehutachiona hweropa.

Munguva yehutano hwose, murwere anoregererwa kunwa doro, sezvo izvi zvinogona kutungamirira kuhutachiona hwechipatara. Izvo zvinoshandawo kumakwenzi ane caffeine ane zvigadzirwa.

Mushonga uri pasi pekufungisisa unobatsira zvakakwana pakukwanisa kwomurwere kugadzirisa kutakura nekuita mune imwe mimwe miitiro inoda kuwedzera kuisa pfungwa.

Mushonga "Kaffetin Cold": siya kubva kumapromita

Mukuona kwekuti iyi mishonga inowanzoshandiswa semishonga inoratidzira, inosunungurwa chete mushure mokunge chiremba chiremba chiratidzwa. Nenzira, zvakaoma kuwana mishonga yakadai mumapromasi. Kazhinji inopihwa mushure mekutanga.

Mishonga yakafanana

Kune nzira dzakawanda iyo ichi chirwere chinogona kushandiswa. Pakati pevakakurumbira ndeyotevera: Amitsitron Forte, Antigrippin, Bol-Run Premium, Vokasept, Grippo, Grippold-N, Gripotsitron Forte, Gripflu, Dolaren, Cold-N, Coldrex, Coldfreak, Lemsp Lemon, Novalgin, Panadol Extra, Rinza, Tamipul, Pharmacitron nevamwe.