Pathogenicity uye virulence zvigare. Virulence - nayo ...

Muviri womunhu musha utachiona anenge 100 trillionov. Masayendisiti anhasi chete ikozvino achinyatsoziva sei munharaunda iyi yakaoma anosangana munhu. Ivo zvazvinoita pfungwa kugaya, masoja emuviri uye zvichida kunyange pfungwa zvakanaka. Zvisinei, kwete utachiona zvose zvinogona vagare muviri norugare uye vachiwirirana. It inonzi pathogenic microorganism anogona kukonzera zvirwere miti, mhuka kana nezvipembenene. Microbes ataure pathogenicity vachishandisa virulence. Saka, chii chiri virulence?

Pfungwa virulence

Virulence - iri izwi kutsanangura mwero pathogenicity ane microbe. Naizvozvo, determinants pakati virulence pakati nayo utachiona chimwe zvayo kuvabereki, nokukanganisika kana STRUCTURAL zvinhu anobvumira chikonzero chirwere.

The ukama pakati hondo uye nayo utachiona vanogara simba, nokuti mumwe anogona kushandura basa uye mashandiro anoita mumwe. Zvaizobuda ukama kunoenderana virulence pakati nayo utachiona uye hama mwero kurwisa kana susceptibility wehondo. An rinokosha riri vakaridza kushanda rokudzivirira zvigadziriswe pakati muviri.

Virulence zvinhu nechokuita zvakananga ehupfumi kuti kubvumira anokuvadza tusingaoneki vapinde kana muviri wehondo chikonzero uye chirwere. Izvi zvinosanganisira kubudisa chepfu kwemabhakitiriya kuti pave pathogenicity.

zvinokosha pfungwa

Invasiveness - kunzwisisa ichi kupinda tishu. Zvinosanganisira zvigadziriswe zvinoita Colonisation uye kugadzirwa extracellular zvinhu kuti pave nomukana nechisimba uye circumvent kana kukunda dzimwe nzira unodzivirira.

Toksogennost - kukwanisa excrete muchetura. Mabhakitiriya anogona kubereka nezvemarudzi maviri zvinokachidza: endotoxins uye exotoxins. Exotoxins abudiswa masero kwemabhakitiriya uye nekusimudzira kukura utachiona. Endotoxins vari muchitokisi fuma.

Chirwere muchetura, zvose soluble uye sero-aishamwaridzana, zvinogona yaitakurwa neropa uye node rinenge uye kukonzera cytotoxic migumisiro munzvimbo kure kubva kutanga pfungwa kupinda. Zvimwe kwemabhakitiriya zvinokachidza anogonawo pave dzaitongwa kubatanidzwa nechisimba.

Pathogenicity uye virulence zvigare

Pathogenicity - mano ane muviri kukonzera zvirwere. Kwaniso iyi ndicho chinhu majini chezvinonhuwira nayo utachiona, iyo anokuvadza hondo divi. For mikana utachiona, kugona ichi kuti hosha haina chokuziva. Utachiona anogona kutaura zvakasiyana-siyana virulence.

Virulence - vanzwisise kuti zvakabatana chaizvo pamwe pfungwa pathogenicity. The mwero virulence pakati utachiona hwakakura kazhinji correlated vachikwanisa kutevedzera pahondo uye kungaenderana zvimwe zvinhu. virulence zvinoita inobatsira kuti pathogenicity, kureva kubatsira kuti zvirwere.

Utachiona

Vakawanda vakaramba wakavhomorwa kuteerera siyana zviziviso chigadzirwa okushambadza kuti vanoti vanouraya 99% kwoutachiona. Utachiona hwakakura - shoko rinoshandiswa kurondedzera diki Utachiona (utachiona uye mavhairasi), zvichikonzera zvirwere zvakasiyana-siyana. Nezvinhu zvipenyu mazwi, izvozvo inonziwo iri causative pomutumwa. Kune mhando inoverengeka utachiona kuti kukonzera zvirwere zvakasiyana-siyana kubvira vanhuwo chando uye nekuguma kenza.

Pathogenic tusingaoneki sei munhu nenzira zhinji, zvichienderana virulence yavo. Virulence - shoko rinoshandiswa kurondedzera kubudirira imwe utachiona hwakakura. The zvakawanda virulent utachiona hwakakura rave, ndipo zvichataurirana inokanganisa utano hwevanhu.

Zvinhu zviri virulence

Virulence Zvinhu zvimwe utachiona kuti kusarudza izvo ane utachiona hwakakura virulence. The zvakawanda, zvikuru rinofanira ichava chikonzero chacho. Zvinhu izvi kupa mukana mukubata hatiwani yevanhu hurongwa, uye zvikuru, zvikuru kuparadza vanogona kuva.

Kune mhando akawanda akasiyana virulence zvinoita kuti chingava chipo kana ndisipo panguva imwe utachiona hwakakura: zvinhu zviri Colonisation, enterotoxins uye hemolysin. Virulence - ari quantitative unhu, rinomirira mwero chirwere yakakonzerwa microorganism. Nyaya iyi, iyo inoratidza kudyidzana pakati utachiona hwakakura uye mutakuri. Virulence kakawanda correlated pamwe nekugona nayo utachiona kuti zvikurumidze kuwanda. Izvi zvinogona kuvimba mutakuri uye zvakatipoteredza zvinhu.

A kwemabhakitiriya utachiona hwakakura kazhinji so chero Utachiona hunokwanisa kukonzera chirwere. Kukwanisa kwaro kukonzera chirwere anonzi utachiona. The virulence of microorganism iri zvakananga novimba hunhu utachiona uye ane chokukomborerwa kwokuomerwa chirwere zvakunokonzera.