"Poliglyukin": mirayiridzo kushandiswa, contraindications, wongororo

"Poliglyukin" - antishock plazmozameshchath medicament hwezvekukurukurirana marambi pamusoro Nyorera mumwe zvisingaoneke. Somugumisiro, kushandiswa kwezvinodhaka ari kutadziswa adhesion pakati maplatelet uye masero matsvuku eropa.

Zvinoumba kuitika "polyglukin"

Hwaro zvinodhaka - dextran. Muna girazi bhodhoro mabhati 200 uye 400 ml kwegadziriro muchimiro ane aqueous mhinduro. The mushonga sezvamunoita rine yavaibvisa chloride uye mvura kuti jekiseni.

pharmacodynamics

"Poliglyukin" mirayiridzo iri kuratidzirana sechinhu mushonga une antiagregatnym uye hemodynamic nemigumisiro. The mushonga chinhu hydrophilic polysaccharide tichisunga mvura. Pashure kushandisa mushonga Nyorera mumwe zvisingaoneke yakadzorerwa munguva pfupi nokuti kuti absorbs mvura yakakwana.

The kushingaira zvinoriumba ane hwakanyatsorwisa yakakwirira samolecular uremu saizvozvo muropa zviri chipo kwenguva refu, uye panguva kutungamirirwa zvishoma nezvishoma ichipfuura ngarava masvingo,. Features zvinodhaka kuti nokukurumidza kuwedzera uye refu kuchengeta BP chakaipa. "Poliglyukin" kunoderedza zvinyama edema, inodzorera Nyorera mumwe zvisingaoneke anobvisa spasm, kunoitika muna peripheral midziyo.

Suspension Kugadzikana inowedzerwa ropa pashure kurapwa "Poliglyukin" mirayiridzo kunoratidza kuti mushonga unoita kuti ropa shoma viscous. Muvanhu, normalized dzemitambo, nokuputswa nokuda kukura nehana: microcirculation, ropa riyerere kuti munyama.

Pharmacokinetics

Excretion kuti medicament anogadzirwa kubva mumuviri kunyanya nokuda neitsvo. Mienzaniso kubviswa rinoitwa mezuva. "Poliglyukin" akabvisa chawaitwa, seasingakoshi mugove waro anopinda mumasero reticuloendothelial emuviri uye yakaiswa imomo zvishoma nezvishoma kunoitika kukamurwa medicament. Nokuda iyi, shuga rinobudiswa, iyo hakunganzi seinokonzera simba. Little "polyglukin" anopinda zvomudumbu turakiti.

umboo

"Poliglyukin" mirayiridzo iri kushanda kunoita kuti basa kana kuputswa ropa chokubuda rirambe richibvira. The chinodhaka yakakodzera pakurapa rinoti nehana uye Madzivirirwe (septic kuvhunduka, chepfu, kutsva, kushandiswa, zvinorwadza). A mushonga kushandiswa rikwanise kurasikirwa neropa zvakaitika panguva ectopic pamuviri, kuzvara kana somugumisiro mupfungwa nokukurumidza vadzorere Nyorera mumwe zvisingaoneke. Solution vari hypovolemia, inova migumisiro yeplasma leakage (kamuri chirwere, kutsva). Kubudirira zvinodhaka riri kuchengetwa mune Implementation pakati matanho zvainanga kudzivisa embolism (preoperative, postoperative).

Contraindications

Asati kurapwa zvakafanira kuteerera contraindications, iyo ine mupanda kuti nzvimbo "Poliglyukin" mirayiridzo Chinyorwa. Contraindications kunorapwa uye kudzivirira rokugadzirira uyu sezvinotevera:

• chepfungwa Kurohwa;
• High ICP;
• inoti iyo yebhuku mvura akawanda ari sadikanwa;
• chirwere pamwe renal chirwere (anuria, oliguria);
• BP yakakwirira;
• mwoyo kutadza;
• kusagadzikana homeostasis, coagulation;
• kuramba womukati ropa (Kunze - BP pazasi 60 mm HG ..).

chipimo chemushonga kurapwa

A mhinduro intravenous yaitonga. Muzviitiko apo kurasikirwa ropa anonzi chenjera kuti akabvumira kushandisa intra-arterial zvinodhaka. Mwero zvinodhaka Urongwa akatsunga nomumwe uye zvinoenderana mukuru ezvinhu omurwere, mwoyo wake zvazvingava, BP uye hematocrit.

By kugwinha inoti "Poliglyukin" mirayiridzo Chinyorwa rinokurudzira chinotarisirwa bolus intravenous nzira. The zvaida kuroora dose kuti vamiririri Muzviitiko zvakadaro hakusi asingasviki 400 asi kwete kupfuura 1200 Rine mamiririta. Mune zvimwe zviitiko zvinokosha kuwedzera dose kurapwa kusvika 2000 Rine mamiririta. Kana chokupika BP pamusana chourongwa zvinodhaka akakwanisa kuunza dzose, mumwe yezwi pakatanga zvinodhaka mumate.

With zvinokosha kurasikirwa neropa, unoenderana 500 Rine mamiririta uye zvakawanda, uyewo kuvapo kwazvo anemizatsii kunze kushandisa "polyglukin" inotoda akaita ropa. Somunhu chokudzivirira chipimo kudzivirira kuvhunduka pakuvhiya zvinodhaka raitongwa kuti kuchadonha kana kumanikidzwa rawa - jeti. The unopinza Kuderera BP 60 mm HG. Art. uye pazasi zvinoda kutanga "polyglukin" mune ruzha mukuru 400 ML intraarterially. Apedza akavhiyiwa vachishandisa ichi mushonga Kudzivirira zvibereko, vachibvumira kudzivisa kukura kuvhunduka.

inotoda yemanyorero rinoshandiswa pana wevasungwa 6% vanoshingaira fuma, asi zvinoshanda "Poliglyukin 33" mune zvimwe zviitiko. Mirayiridzo yokushandisa kunoratidza kuti idzidziso aine Kuwanda dextran ndiyo webetsero reagent apo kuongorora kugarisana ari kugamuchira uye anyatsoronga.

Kana zvakakodzera kubvisa kokutsva kuvhunduka, pazuva rokutanga mukuru chinotarisirwa kubva 2 zviuru. Chiuru kune 3. ML mhinduro, rinoshandisirwa pazuva asina kupfuura zviuru 1.5. Ml gadziriro yechipiri. In avo Muzviitiko kana kuvhunduka zvakakodzera kubvisa mwana, hazvina kutanga chinotarisirwa 40-50 Rine mamiririta / makirogiramu nzira, pazuva rechipiri dose paminiti kilogram muviri uremu ipfupi kuti Rine mamiririta 30. Kuzvidzivirira chipimo, kubvisa mukana nehana, vana kusuma donhwe intravenous nzira. The aida dose mwana anoda kubva Rine mamiririta 10 kusvika 15 / makirogiramu "Poliglyukin" gadziriro. Mirayiridzo kushandiswa mhuka, zvakare, zvinoita kuti tikwanise kushandisa kurapwa, kwakavakirwa okusuma "polyglukin". Nokuti zvinangwa izvi zvisaitika dose 15 kusvika 20 Rine mamiririta / makirogiramu. The zvakakodzera zvikuru dose zvinodhaka kunotemwa nachiremba.

nemishonga

Asati kushandisa chigadzirwa "Poliglyukin 'mirayiridzo kushandiswa, mhinduro vanokurudzirwa kudzokorora zvingakonzerwa nemishonga. Kazhinji yematambudziko regai simuka, uye muviri wevarwere vanobvuma zvakanaka zvinodhaka. Dzimwe nguva zvinogona kuonekwa muchimiro neutachiona ose anaphylactic nehana, kuzvimba, kuvaviwa uye mapundu. Mune vamwe varwere, kuti sternum pane kunzwa compression, pane marwadzo. Dai kuvapo fivha, akaderedza BP, kumhanyisa nomwoyo unodiwa. Unogona kuva nezvinetso kufema, dzungu uye kuvapo acrocyanosis kukura. Somugumisiro ovhadhozi vakatakura imwe mutoro pamusoro mwoyo, unorambidza kusapfuudza rakarumbidza dose rinoreva "Poliglyukin" mirayiridzo Chinyorwa. Mahwendefa nemimwe mishonga izvo murwere achitora, anogona kuvhiringa Zvakaitwa mhinduro.

Analogs Wongororo

Kuzvitsinhanisa medicament anogona "HyperHAES", "Reoglyumanom" kana "Hai-chena". Zvinogadzirisa zvinoshandiswa nechinangwa dzakafanana "Poliglyukin" zvinosanganisira "Sterofundin", "Reopoligljukin", "Stabizol".

Tsiva "Poliglyukin" mirayiridzo kushandiswa kubvumira muzviitiko apo murwere hakukodzeri chivako ichi. Vokutsiva zvinogona kushandiswa "gelofusin", "Refortan N», «Sorbilakt". A ndozvinoitawo rinogona kushandurwa kuti "Albunormom" uye "Neorondeksom".

Reviews dzinoratidza kuti vakawanda zvinodhaka inobatsira kubvisa dambudziko. Asi sezvo nechimwe yakasiyana, migumisiro chourongwa yake angava akasiyana. Zvakawanda zvinoenderana murwere ezvinhu. Vanhu pangozi kwete kushandisa "Poliglyukin" pachavo, nokuda mikana chourongwa kukodzera mari uye kukura nemishonga.

Its basa mhinduro "Poliglyukin" anoita, asi kurapwa, uyewo Implementation muzvidzivirire, hazvina runziro uye kwakaita kuti zvimwe zvinetso, asi dose zvinodhaka kunofanira kusarudzwa nachiremba nomumwe. nyanzvi chete anogona kutarisira kuti mushonga sezvo munhu wose asina vaizokwanisa zvakarurama kuona inodiwa dose uye zvakakodzera nzira chourongwa kurapwa. Kunwisa mishonga zvinodhaka zvine ngozi nokuda mwoyo, saka musatora ngozi, uye kuzvinzwira medicate.