Polycythemia wechokwadi. Zvinokonzera, Zviratidzo, nechirwere, Treatment

Polycythemia - ihosha iyo inogona tsunga nokutarira chete panguva chiso yomunhu. Uye kana isu tiite chirwere bvunzo, asi mubvunzo uye haagari. In mabhuku ezvokurapa pane mamwe mazita zvokurwara ichi: erythremia, Vakeza chirwere. Pasinei rokuti, hosha zvinokonzera chikuru pangozi upenyu hwevanhu. Munyaya ino tichakurukura muudzame hukuru zvikuru mashandiro kuti panowanikwa yayo, chikuru zviratidzo, matanho uye kurapwa vakapa.

Vhuṱanzi

Under polycythemia zvinoreva myeloproliferative kenza ropa umo mumwongo unobereka masero matsvuku ropa yakawandisa. To muduku pamwero mumwe enzayemu zvinoumba kuwedzera wakacherechedza, kureva leucocytes uye maplatelet.

masero matsvuku eropa (RBCs zvimwe) nomuti okisijeni, masero ose evanhu, pokuvanunura kubva mumapapu kusvika mugadziriro zvomukati. Vanodawo basa kubviswa carbon dioxide inobvisa kubva munyama uye kumuendesa kune mumapapu kuti tevera nedzinovengwa.

Erythrocytes anobudiswa ichi- mu mumwongo. Zviri spongiform muzvizhinji munyama vemunyika mukati pfupa, uye ndiye nedanho hematopoiesis.

Leukocytes - chena ropa masero kuti anobatsira kurwisa zvirwere. Maplatelet vari anuclear sero zvimedu nokuda nyonganyonga vascular nokuvimbika. Vane kukwanisa kuomerera mumwe uye occlude buri, nokudaro zvokurega kubuda ropa.

Polycythemia kwechokwadi kunoratidzwa nokutaurisa masero matsvuku eropa.

Kupararira

zvokurwara iyi kazhinji chirwere nedzevakuru, asi munogona kuyaruka uye vana. The chirwere haigoni kubatwa kwenguva refu, ndiko asymptomatic. Maererano zvidzidzo, avhareji yezera varwere anoda kubva 60 kusvika 79 makore. Vechiduku zvikuru kashoma kurwara, asi chirwere anomhanya navo zvokuvapfuura. The vamiririri simba pabonde, kana uchitenda nhamba, kanoverengeka kakawanda chirwere polycythemia.

pathogenesis

Vazhinji zvoutano chokuita nechirwere, kunoitika nokuda chichiitwa kuwedzera nhamba masero matsvuku eropa. Somugumisiro, ropa anova wakanyanya gobvu.

Ukuwo, vakawedzera ayo viscosity chinokurwadzai paumbwe clots (thrombi). Vanogona kukanganisa dzose ropa nokuyerera kuburikidza arteries uye mutsinga. ezvinhu akadaro kazhinji kukonzera shamhu uye mwoyo kurwiswa. The ndechokuti gobvu ropa kakawanda midziyo nguva nomumugwagwa kwaitora nguva. The mwoyo une richiva zvakawanda kuedza chaizvoizvo kumusundira.

Tava kuderera ropa kuyerera haibvumiri zvomukati kuwana inodiwa okisijeni. Izvi zvinosanganisira kukura mwoyo kukundikana, kutemwa nomusoro, angina, simba uye nezvimwe zvinetso zvoutano, izvo hazvifaniri kusiyiwa vasina akavatarisa.

kupatsanura zvirwere

• I. The kwokutanga Danho.

1. Rinotora kwemakore 5 years kana kupfuura.
2. The chirwatata nomumhu.
3. miedzo ropa anoratidza mwero kuwedzera nhamba masero matsvuku eropa.
4. Matambudziko kashoma chirwere.

• II A. polycythemic danho.

1. Duration kubvira 5 makore anenge 15.
2. Pane kuwedzera zvimwe nhengo (chirwatata, chiropa), kubuda ropa uye thrombosis.
3. Nzvimbo bundu iri chirwatata pacharo haaiti.
4. Ropa kungakonzera simbi kushayiwa mumuviri.
5. Mune Kuongororwa ropa pane kuwedzera kwakuri mumasero matsvuku eropa, ropa masero machena uye maplatelet.

• II danho B. polycythemic pamwe myeloid metaplasia chirwatata.

1. Inoongorora kuratidza yakawedzerwa kugutsikana masero ose ropa, kunze lymphocytes.
2. Pane neoplastic kwacho ari chirwatata.
3. The kunotoda mufananidzo kuparadzwa rinowanika, thrombosis, kubuda ropa.
4. Mumwongo iri zvishoma nezvishoma inotungamirwa mavanga.

• III. Neta neta Danho.

1. Muropa, pane rakapinza kuderera erythrocytes, maplatelet uye leukocytes.
2. Pane raidudzwa kuwedzera kukura chirwatata uye chiropa.
3. kazhinji danho iri anova mukati mumakore 20 pashure nokusimbisa nechirwere.
4. The chirwere chinogona kuchinjwa kuva chakasimba kana chirwere neleukemia.

The zvinokonzera chirwere

Zvinosuruvarisa, zvino nyanzvi havagoni kutaura chii zvipi kutungamirira kukudziri- kwezvirwere zvakadai polycythemia kwechokwadi.

Most kurerekera kune nemavhairasi-magene dzidziso. Maererano naye, inokosha nemavhairasi (pane zvidimbu anenge 15) vari chakaunzwa nomuviri womunhu uye pasi pokudzora zvimwe zvinoita kuti kukanganisa masoja kuzvidzivirira, kupinda munzvimbo mumwongo uye node nodes. Masero vaive panzvimbo ichiibvira nokukurumidza otanga uye muwande, pova itsva zvimedu.

Ukuwo, polycythemia chikonzero angave inovandira panzvimbo nhaka kubatwa. Masayendisiti nekusimba kuti chirwere ichi vari tichikurumidza kuvhara nehama munhu anorwara, uye vanhu vane havachanyatsogoni maumbirwo okutodza.

Predisposing nechirwere zvinhu

• X-ray irradiation, ionizing nemwaranzi.
• Intestinal noutachiona.
• Wanda.
• Tibhii.
• Surgery.
• Kakawanda mupfungwa.
• kushandiswa Long-rokuti vamwe mapoka zvinodhaka.

zvekuchipatara mufananidzo

Kutanga kubva Danho rechipiri nehosha, ari pathological muitiro vanokweverwa zvinenge gadziriro dzose nhengo dzomukati. Pasi apa ndizvo kuzviitira kunzwa murwere.

• Kuneta uye ichifamba famba pfungwa kuneta.
• Inosimudzira vangadikitira.
• Kunoshamisa Kuderera vaita.
• Chakakomba nomusoro.
• ndangariro vanotaura.

Polycythemia wechokwadi rinogonawo pamwe zvinotevera zviratidzo. Muchiitiko chimwe nechimwe nekuomarara yavo dzinosiyana.

• Mutsinga uye kushandura Hue ganda. Varwere cherechedza kuvapo mutsinga zvakajeka. In chirwere ichi ganda dzinoratidzwa yakatsvukuruka-tinged Cherry, zvinonyanya kuoneka pamusoro pachena nhengo dzomuviri (rurimi, maoko, chiso). Miromo zvitema, meso ake aiita akatsvuka. Izvi Kuchinja nechitarisiko nokuda nokupararira nechepasi ropa midziyo, uye chakaratidza slowdown racho kukwidziridzwa.
• Itchy ganda. chiratidzo ichi rinowanikwa muna 40% nyaya.
• Rodonalgia (zvinopfuura rinopfuta marwadzo panguva kumuromo kwematanda minwe nezvigunwe, izvo aine akatsvuka ganda). The kwaita chiratidzo ichi Rinobatanidzwa vakawedzera nhanho ropa maplatelet uye inotungamirwa mikrotrombov.
• Kuwedzera kukura chirwatata.
• Chimiro nemaronda mudumbu. Nokuda duku mudziyo thrombosis mucosa muviri anorasikirwa kurwisa varo Helicobacter pylori.
• clots ropa. zvinangwa zvavo zviri kutsanangurwa rakawedzera ropa viscosity uye kuchinja vascular masvingo. Kazhinji, zvinhu zvakadaro kunoita kuti nokuvhiringidzirwa kweropa iri dzakaderera maoko nemakumbo, chepfungwa uye coronary nemidziyo.
• Marwadzo makumbo.
• Heavy ropa kubva matadza.

Diagnostics

Zvikurukuru chiremba anounganidza rakazara zvokurapa nhoroondo. Iye anogona kukumbira inoverengeka kugadzirisa mibvunzo: kana akazviratidza kusagadzikana / breathlessness / kunorwadza kusanzwa, etc. No zvisinganyanyi kukosha kuona pamberi chisingaperi zvirwere, tsika dzakaipa, zvinobvira kuonana zvine chepfu ...

Zvadaro, mumwe kuongorora chaiko. Mazvikokota anosarudza ruvara rweganda. By palpation uye tapping anoratidza yakawedzerwa chirwatata kana chiropa.

Nokuti nokusimbisa zvirwere miedzo ropa fanira anogadzwa. Kana murwere ane zvokurwara ichi, muedzo zvabuda ndeinotevera:

• Kuwedzera masero matsvuku eropa.
• Dzakakwirira parameters hematocrit (chikamu masero matsvuku eropa).
• High Chizenga parameters.
• Low kwevari erythropoietin. kemikari Iri basa kweiyi mumwongo iri masero matsva matsvuku.

Chirwere kunorevawo uropi biopsy uye aspirate. Wokutanga shanduro kudzidza kunosanganisira yaunodya nemvura kuuropi, uye biopsy - chikukutu constituent.

polycythemia chirwere kwakaitika nemiedzo kuti Gene mutation.

Chii chinofanira kubatwa?

Chose kukurira chirwere akadai polycythemia wechokwadi, hazvibviri. Ndokusaka ARV pfungwa chete pamusoro kuderedza zvekuchipatara kuratidzwa uye kuderedza thrombotic matambudziko.

Varwere vakanga achinyanya basa ropa riyerere. nzira iyi kunoreva kubviswa shoma ropa (kubva 200 kusvika Rine mamiririta anenge 400) pamwe hunorapa nechinangwa. Zvakafanira kuti normalization pamusoro quantitative parameters ropa uye kuderedza viscosity kwayo.

Varwere vari kazhinji ushandiswe "asipurini" kuti yekuzvidzivirira dzichiri-siyana thrombotic yematambudziko.

Mishonga inoshandiswa kuramba zvakajairika hematocrit, kana paine kwakakomba kuvaviwa, kana kwakawedzera thrombocytosis.

Mwongo transplantation rinoitwa munyika chirwere ichi apo neapo, sezvo zvokurwara panyaya zvakakwana kurapa hakusi inouraya.

Zvinofanira kuzivikanwa kuti marapiro zvaiitwa neimwe nyaya dzakasarudzwa nomumwe. The kurapa-pamusoro apa ndeyokuti informational zvinangwa chete. Hazvina varumbidzwa kuedza kukurira chirwere ichi.

zvinogoneka yematambudziko

The chirwere chakakomba zvakakwana, saka usaregeredza kurapwa kwayo. Zvikasadaro, zviri kuwedzera mukana wokuti zvisingafadzi yematambudziko. Izvi zvinosanganisira zvinotevera:

• clots ropa. Zvinokonzera pathological muitiro angave inovandira panzvimbo kuwedzera ropa viscosity, kuwedzera masero eropa matsvuku, uye maplatelet.
• Urolithiasis uye gout.
• Ropa, kunyange pashure zviduku maoparesheni. Kazhinji, dambudziko rakadaro vakasangana pashure zino dzokubudisa.

mataridzikiro

Vakeza chirwere - isingawanzowanikwi chirwere. Zviratidzo kuti kuitika mukutanga mumatanho waro kukura, zvinofanira kuva chisakiso pakarepo kuongororwa uye kutevera-up kurapa. Pasina zvakakwana kurapwa, kana hosha haina chirwere nenzira yakakodzera nenzira, rufu kunoitika. The chikuru chinokonzera rufu kazhinji vanoita vascular yematambudziko kana Kushandurwa chirwere kuva chirwere neleukemia. Zvisinei, hwakakwana kurapwa uye kunyatsotevedza vanorumbidza zvose kubva chiremba anogona yekudyidzana kuwedzera upenyu murwere (makore 15-20).

Tinovimba kuti zvose mashoko munyaya yaizova zvechokwadi kubatsira iwe. Stay utano!