"Prepidil" (gel): description, mirayiridzo kushandiswa uye dzinovaka. Gel kuitira induction zvesimba

Sei kushandisa zvinodhaka akadai "Prepidil" (gel)? Inofambiswa kubudirira chinodhaka, uyewo zvairatidza chokushandisa ichi chichange kurondedzerwa akaderera zvishoma. Tinewo anopa mashoko pamusoro sei kushandisa akati chinodhaka, zvakadini tinorasikirwa uye chii chiri uchishandisa musimboti.

Description, kavha uye akafanana

Ndeupi pasuru inowanika zvinodhaka "Prepidil"? intracervical gel chakatengeswa mupurasitiki kuraswa syringes wakakwana anobudisa mushonga zvishoma nezvishoma. Ivo mukavaisa Maronda akasiyana uye makadhibhokisi mabhokisi ari, ukuwo.

Translucent uye viscous zvinodhaka "Prepidil" (gel) rine rakadaro rinoita wemafuta sezvo dinoprostone. Ebetsero zvinhu akawedzera kwachiri colloidal anhydrous silica uye triatsetilglitserol.

mashandiro chiito

Chii chinodhaka "Prepidil"? Gel panguva yokusununguka kunomutsa remuromo ichiibvira. Its vanoshingaira mumiririri chinhu unsaturated nuna asidhi kuti synthesized pasi vasiri ezvinhu.

Dzakananga mushonga chiito musimboti waro intratservikalno kushandiswa haina kudzidza. Zvisinei, nyanzvi dzinofunga kuti dinoprostone kuti kutsigira remuromo ropa aibuda, nokudaro kuwedzera kuibvisa ayo (kunyoroveswa, rimire uye buri). Zviito zvakadaro zvakazara enderana anowanzoita inoyerera Generic kuchinja kutungamirira vasanyanye remuromo nemishonga uye awedzere myometrial marwadzo, uyewo pakukurukura.

Tinofanirawo kuziva kuti chikonzero che mari kunogonawo kuva kunobatsira zvikuru pamusoro tsandanyama ari zvomudumbu turakiti. Mune zvisingawanzoitiki kacho chinokurwadzai svoto uye kurutsa ari mukadzi pamuviri.

At dzakakwirira dosages dinoprostone vanogona BP (nokuda kukuvara vascular wakatsetseka tsandanyama, uye capillaries), uye kuti kumutsa muviri tembiricha. Zvisinei, zvinofanira kucherechedzwa kuti migumisiro izvi zvose hazvina kuchengetwa kana zvakanaka achitora chinodhaka, kureva panguva kunokurudzirwa mishonga kuti remuromo ichiibvira.

kinetics

Ndezvipi yokusafa kinetic parameters medicament "Prepidil"? Gel, iro rine mutengo mberi intracervical pashure kwokubatsira 500 .mu.g rinosvika kunonyanyisa wevasungwa muropa mushure maminitsi 35-45. Zvadaro, zviri basa fuma yava wakaderedzwa kusvika kwokutanga padanho (zvisinei uterine basa).

Dinoprostone pamwe sealbumin kwevanhu anosunga 73%. Saka basa wemafuta zvinodhaka riri kukamurirwa nyama uye muviri zvinwiwa zvose parturient.

Kunyanya dinoprostone rinoita mumapapu, uye itsvo uye chiropa. In kwevanhu ropa uye weti aonekwa kanenge pfumbamwe metabolite prostaglandin E 2.

Vazhinji vanoshingaira chirungiso "Prepidila" iri outputted nokuda itsvo, asi riri shoma - pamwe chete mutsvina yadzo.

umboo

Sei Ndinoda mishonga "Prepidil" sei? Gel kunobatsira ude remuromo ichiibvira. Zvinonzi chete kushandiswa kana yakaratidza kuti basa.

Contraindications

Gel kuitira induction basa harina kushandiswa ezvinhu ayo contraindicated nokuda mazhinji uterine sunga. Idzi dzinosanganisira:

• pamuviri pevana vakawanda;
• kusavapo kupinza of fetus musoro;
• kubva 6 wenguva izwi pamuviri;
• zvinorwadza kana chakaoma kubereka (kusanganisira nhoroondo);
• Kuvhiya pamusoro dumbu kana cesarean chikamu (kusanganisira nhoroondo);
• Saizi mismatch chiuno rwaamai uye fetus musoro;
• fetus nhamo (asati);
• mamiriro ezvinhu umo kuvhiya kupindira pane zvinodiwa;
• kuvhiringidzika fetus mwoyo mutinhimira;
• reropa zvinoerera kubva dzokubereka turakiti panguva pamuviri (kuti asingazivikanwi mavambo);
• dzokubereka turakiti Zvirwere (dzakaderera mapoka);
• kanganisika fetus mharidzo ;
• hypersensitivity kune zvimwe gel.

Zvokungwarira aionekwa muiti rinoshandiswa neBP, zvemwoyo, hepatic dysfunction, Árbol asima, havachanyatsogoni itsvo basa, yakaratidza zai, ocular neBP kana yemaziso.

Drug "Prepidil" (gel): Instructions

Sezvo kwokutanga chipimo chemushonga kushandisa zviri yose sirinji nokushandisa nokuti iyi zvakabatanidzwa anobudisa mushonga zvishoma nezvishoma. Zvinonzi akasuma kupinda remuromo canal, riri pazasi ufanane womukati Os.

Kamwe gel kwave akapinda, mumwe mukadzi ari kusununguka vanofanira ¼ maawa avete shure kwake. Izvi zvinokosha kuti kuderedza leakage zvinodhaka.

Kana kurudziro pane kwokutanga dose mishonga hakuitiki, kuti medicament chinotarisirwa zvakare (pashure maawa 6). The dose nokuti akadzokorora vaitarira mushonga anoramba kuzochinja.

Kudiwa mamwe kushandiswa gel iri pakutsvaga kunotoda mamiriro ezvinhu.

The kunonyanyisa dose daily vaiona medicament iri 1.5 MG.

Dosing

Ndingatarira kushandisa gel kuitira induction zvesimba? Instructions rine anotevera incremental:

• Rongonyora ari chena sirinji uye anobudisa mushonga zvishoma nezvishoma.
• Bvisa sirinji muromo chivharo.
• Dzinoisa mashoko sirinji chivharo (mhiri) kushandiswa ari pisitoni.
• Vaiisa anobudisa mushonga zvishoma nezvishoma (zvakasimba) kuti muromo sirinji kuti doro kwakaitika.
• Kupinda mai itsva zvose zviri sirinji.

nenjodzi

Ndezvipi kurutivi migumisiro mishonga inogona kukonzera "Prepidil"? Gel mu parturient inokwanisa afunge titanic uterine sunga (kuwedzera ayo inzwi, kakawanda uye nguva yose sunga), uyewo kuda kurutsa, uterine atsamwira, kurutsa, musana marwadzo, manyoka, fivha, hypersensitivity siyana uye nokudziya manzwiro ari nyinyo.

Mugore fetus zvinodhaka kunogona kukonzera kutambudzika chirwere, uyewo kushandura mwoyo zvazvingava, kuderedza tinyatsonzwisisa achangoberekwa mamiriro ari Apgar mamakisi kusvika 7 points. Pakati pezvimwe zvinhu, kushandisa zvinodhaka haawanzopiwi ndakatendeka, asi achiri hunokonzera kubereka mwana akafa.

Drug "Prepidil" (gel): wongororo uye mutengo

Mari mari zvakakwirira zvikuru. Imwe sirinji pamwe gel inogona kutengwa nokuda 580-650 rubles. Zvinofanira kucherechedzwa kuti kushandisa zvinodhaka ichi kunodiwa chete muchipatara.

Vanachiremba vanoti kushandiswa "Prepidila" vanofanira kutanga kuongorora zvaidiwa kuti chiuno wevakadzi uye fetus kukura musoro. Kana vasinganzwi kunowirirana, ipapo mishonga haina kushandiswa.

Maererano varwere, nyaya mumiririri kunogona kukonzera guru yakawanda nemishonga, kusanganisira mwana upenyu pangozi. Saka, vakawanda vavo vanoramba kushandisa gel ichi, kunyanya pashure richisvika makore 35 ekuberekwa.