The mushonga "Proksium": mirayiridzo kushandiswa, dzomuzana chaiwo

Sei kushandisa zvinodhaka "Proksium"? Mirayiridzo kushandiswa kwezvinodhaka inorondedzerwa munyaya zvinhu. Mariri uchawana mashoko pamusoro fomu umo akati medicament yakaitwa, kana akanga chero analogues umo kuitira akagadzwa uye zvichingodaro.

The chimiro, kavha, Zvinoumba zvinodhaka

In chii chimiro anogadzirwa ndiwo mushonga se "Proksium"? Mirayiridzo dzokushandisa kunoratidza kuti zvinodhaka izvi inowanika ari Mahwendefa chena makadhibhokisi packs it, uyewo kuva lyophilizate pamwe ampoule pamusoro solvent (10 ML).

Chimiro zvinodhaka pacharo wokutanga unotora munhu pantoprazole (40 MG), uyewo mamwe zvinhu. Panyaya chinu lyophilizate, ipapo inosanganisirawo 40 MG vane basa chirungiso + yavaibvisa hydroxide.

Pharmacodynamics medicament

Zvii rine mushonga "Proksium"? Mirayiridzo dzokushandisa inoratidza kuti ichi Anti-urikanwi uye antisecretory nevamiririri.

Mushure kutora mushonga mukati maro inoperera kugadzirwa hydrochloric acid. Izvi kunoitika pamusana zvichivhiringidza zvinoitwa hwepurotoni kushandisa, riri parenteral masero ari mudumbu.

The rinoita mushonga fuma inokwanisa kuderedza basal uye pentagastrin-dzinovhurika enzayemu, zvokudya uye jekiseni, gastric secretion. Mukuwedzera, zvinodhaka kuchititadzisa rinokosha basa kwemabhakitiriya Helicobacter pylori. Sezvazvakanyorwa anozivikanwa, pamwe chacho vanoshingaira kubereka vanoti paumbwe nemaronda uye erosions mune mucous membranes mudumbu masvingo.

Kuwedzera pane zviri pamusoro apa, vaiona zvinodhaka kunowedzera efficacy vamwe inorwisa utachiona nevamiririri.

Pharmacokinetics zvinodhaka

Chii mushonga une pharmacokinetic ehupfumi "Proksium"? Mirayiridzo dzokushandisa vaudza varwere nezvokuti mushure dose zvinodhaka maturo rekutanga kukura nokukurumidza uye kunotora mazuva.

The chepamusorosoro zviri zvinodhaka ari plasma vakachengeta maawa mana mushure mekugamuchira mureza chipimo chemushonga 40 MG. The mwero payakabatanidzwa pamwe mapuroteni ndiyo 98%. Nguva zvinodhaka hafu-upenyu rinosvika maawa maviri.

Rinobva mushonga kuburikidza neitsvo ura.

Pantoprazole wefodya mukati ura duku. The bioavailability of fuma iri vanenge 75%.

Muviri kwezvinodhaka vanoshingaira pazvokudya chiropa. Kana izvi zvaitika kuti conjugation maitiro, dealkylation uye oxidation pamwe zvakananga Kupinda ane enzayemu akadai cytochrome P450.

Tinofanira kuonawo kuti vaiona chinodhaka nyore chinoyambuka ropa-uropi nokuidzivirira. Uyezve, inomira kunze chete wamai mukaka.

In vakwegura, plasma wevasungwa uye bioavailability zvinodhaka kwakakwirira zvikuru kupfuura Varwere vaduku.

In pamberi cirrhosis zvinodhaka zvinogona outputted kuti maawa 9.

Kana achiita?

Zvino munoziva kuti zvinodhaka "Proksium". Mirayiridzo yokushandisa, wongororo pamusoro mushonga kunoratidza kuti zvairatidza ayo aizoshandiswa zvinosanganisira zvinotevera zvirwere:

• dumbu maronda uye 12 duodenal urikanwi (kusanganisira nguva exacerbation);
• mabatiro kwemabhakitiriya Helicobacter pylori (kubvuma chete chikamu kunzwisisa kurapa);
• reflux esophagitis uye Zollinger-Ellison urwere;
• vakawedzera kugadzirwa gastric muto;
• mufananidzo nyoro pamusoro reflux esophagitis.

Haugoni kushandisa

chero contraindications ine mushonga se "Proksium" (Mahwendefa)? Mirayiridzo dzokushandisa vaudza varwere kuti chimiro iyi mushonga chero zvazvingava hakufaniri ushandiswe kana:

• hepatic kukundikana, yakanyanya;
• pamuviri;
• malignancies mu mapazi ari nemudumbu;
• achiyamwa;
• Kurwara kune mishonga zvinoriumba izvozvo;
• vana pasi pemakore 14.

Panyaya mhinduro iri ndiro, hazvina pachii varwere neutachiona kuti "Pantoprazole". Uyezve, chimiro ichi mishonga chero zvazvingava hazvigoni pamwe chete "ATV".

Mahwendefa "Proksium": mirayiridzo kushandiswa

Analogs Anti-urikanwi zvinodhaka zvichakurukurwa panopera nyaya. Muchikamu chino, tichanzwisisa nezvamai sei mushonga uyu anofanira kutorwa pasi zvimwe zvirwere.

In agadza zvinodhaka "Proksium" vanachiremba vakawanda havo hwendefa fomu. Kana murwere arikutadza pamwe pakuparadza, ipapo ndishandise mhinduro.

The chipimo chemushonga zvinodhaka, uyewo kugamuchira nzira inofanira kutsunga nachiremba wako chete.

Saka sei kutora zvinodhaka "Proksium 40"? Instruction (kutengeswa hwendefa zvinoreva kuti Pharmacies zvose) rinoti zvavakabvumirana chipimo chemushonga zvinodhaka riri MG 40 pazuva. The mushonga akatorwa panguva kana mushure kudya, kunwa mvura yakawanda.

Kana diagnosing gastric urikanwi kana kukurwa kwevhu dose daily yakawedzera kusvika 80 MG.

Nokuti pakurapa duodenal urikanwi mishonga 12 akatorwa kwemazuva 15-30. Kana reflux esophagitis, uye gastric maronda, mishonga yezvirwere dzakadaro vanofanira kuva kupfuura 2 months.

Kubvisa Helicobacter pylori utachiona murefu 1 piritsi kaviri pazuva. Ya kurapwa uyu 2 weeks.

Varwere vanenge itsvo kukundikana, uyewo vanhu vakwegura zuva nezuva chipimo chemushonga haina chinotarisirwa anopfuura 40 MG.

Kana chiropa kutadza uye zvikuru chiropa cirrhosis mushonga anobvumirwa kutora 1 Hwendefa ose rimwe zuva.

Kugadzirisa "Proksium": mirayiridzo kushandiswa

The ampoules gadziriro hwakadaro nachiremba nemumuromo yaitonga hazviiti.

Into chinu chine lyophilisate yakadururirwa 10 ml mumuviri mhinduro. Dzimwe nyanzvi dzinokurudzira chakadaro mushonga iri mberi hwakakanyiwa 100 ml 5% shuga mhinduro.

Intravenous aizomupa vanofanira kugara kwemaminitsi maviri (zvimwe inenge ¼ awa).

The mushonga Kugadzirisa rinofanira kushandiswa pakarepo pashure maererano yenhengo zvose. Kana izvi haamanikidzwi, ipapo mushonga igadzikwe ari kutonhora kamuri uye kushandisa hapana papera pane maawa 12.

Ya yokurapa saka medicament zvakafanana piritsi fomu. The kunonyanyisa nguva kurapwa - 2 months.

In chirwere akadai reflux esophagitis, mushonga chinotarisirwa mune mari mumwe bhodhoro ose zuva.

Nokuti kurapa ropa kuti kwakaitika pane imwe urikanwi 12 duodenal urikanwi uye dumbu kenza uyewo kudzivirira zvazvo, mushonga rinoshandiswa 80 ml nomutsinga (bolus).

Nhanganyaya zvinodhaka kwakaratidzwa infusomats ichi uchishandisa 8 MG paawa.

Apo Zollinger-Ellison chirwere uye hypersecretion medicament waakaudzwa 80 MG. chiremba kungawedzera dose kusvika 160 MG kana zvakakodzera. Muchiitiko chino, zvinodikanwa ive 2 mishonga.

Nokukurumidza kuderedza acidity pakati gastric muto, kazhinji uchishandisa 80 MG zvinodhaka kaviri pazuva.

zviitiko ovhadhozi

Chii zviratidzo kuitika apo yepamusoro mishonga "Proksium" chinodhaka (40 MG)? Manual inoti pari kwakadaro kacho hapana mashoko.

Kana achiita mishonga nomutsinga (kunonyanyisa 240 MG) iri akashivirira kwazvo. Kana kushandisa yakawanda ari chinodhaka, zvakakodzera kushandisa kuvariritira uye detoxification mishonga.

Nyanzvi dzinoti kuti ovhadhozi "Proksium" mapiritsi kungawedzera simba uye kakawanda nemishonga. Muchiitiko chino, kunwa mapiritsi.

nenjodzi

Chii pasingadiwi Migumisiro zvingaitika Varwere pakugamuchira "Proksium 40" chinodhaka? Instruction inoti kushandiswa chokushandisa ichi kazhinji zvinoguma:

• kupatira, marwadzo mudumbu, manyoka uye flatulence;
• cephalgia.

Dzimwe nguva, varwere gona:

• kuvaviwa uye ganda rashes;
• kurutsa;
• arthralgia;
• kuoma kwezvinhu mucous membranes;
• zvakawedzera havi;
• belching;
• Angioedema;
• simba uye Hope;
• dzungu.

Uyewo, zviitiko zvinotevera abnormalities kunge akashuma:

• kuora mwoyo, myalgia, Lyell urwere, mapundu, Stevens-Johnson urwere;
• vakawedzera basa chiropa makemikari, jaundice, zvakakuvadza hepatocytes, fivhiri, nephritis;
• aikanganiswa nechiedza, thrombocytopenia, leukopenia;
• thrombophlebitis (chokuita mhinduro kunoitika panguva jekiseni panzvimbo);
• tremor, kutya, kuderera mune kunzwa uye zvakaratidzwa;
• mburwa, alopecia, hyperglycaemia.

zvinodhaka kwavatori

Ndeupi ehupfumi zvinodhaka murwere kuziva usati kutora mushonga "Proksium"? ichi chinoreva mirayiridzo kunoratidza zvinotevera zviri:

• mishonga Viewed dzinogona kubatanidzwa pamwe "Diclofenac" zvine caffeine "glibenclamide" panyaya iyi "phenytoin", "metoprolol", "diazepam" "nifedipine", "carbamazepine" "theophylline", "digoxin" uye kudzivirira pamuviri hormone vamiririri "naproxen" uye "digoxin".
• Hazvina kunaka kutora mudziyo pamwe "ATV".
• anticoagulants yakadaro coumarin se "phenprocoumon" uye "Warfarin" akabatana "Proksiumom" kungaita kuti vasanyanye PB.
• No akaora chinokosha zvinodhaka aiita "metronidazole", "amoxicillin" uye "clarithromycin" kunge kuzivikanwa.
• Pantoprazole akazoita absorbability mishonga, iyo bioavailability iyo paupenyu ph kukosha gastric muto zvakananga (somuenzaniso, "Posaconazole", "ketoconazole" "Itraconazole" "Atazanavir", "Erlotinib").
• The Rakabatanidzwa vaiona medicament "MTX" kazhinji kunotungamirira kune nokuwedzera ekupedzisira toxicity.

chaizvo kurumbidza

Ndezvipi zviri zvinodhaka anofanira kuudza chiremba usati basa rako murwere mushonga akadai "Proksium" (Mahwendefa)? The Mirayiro yakatora izvi medicament, zvaida kuverenga. Rakati kuti zvinodhaka izvi hakubvumidzwi kutora vanhu vane huta dyspepsia.

Kana muchigamuchira mushonga kuti anopfuura mitatu, murwere anogona kutanga hypomagnesemia. Zviratidzo chirwere ichi vari: chinyamunhari chinorwadza, kurukutika, tetany, delirium, dzungu uye ventricular arrhythmia. Mune chiitiko zviratidzo zvakadai mishonga anofanira aparadza uye pakarepo kubvunza chiremba wako.

Asati kurapwa uye pashure ayo kuvhara gastroendoscope hazvo kunze kuziva mamiriro ose ura. Zvinofanira kurangarirwa kuti pantoprazole zvinogona nyore chaizvo kuti masiki zviratidzo malignancy.

The kunonyanyisa dose pazuva vakwegura uye kuti varwere zvinetso zviri itsvo 40 MG. Nokuti varwere cirrhosis nezuva huwandu mishonga kuti kuderedzwa nehafu.

Zvipatara inotaura nzira, ari zvisingawanzoitiki zviitiko, kutungamirira kukudziri- campylobacteriosis uye salmonellosis.

Purotoni pombi FIs kuwedzera ngozi mapfupa mitswe vakwegura munenge 30% (refu-refu kurapwa).

Analogs uye anoreva zvakafanana zvinodhaka

Zvino imi munoziva zvinhu uye sei kutora zvinodhaka "Proksium". kushandisa nzira iyi yokudzidziswa paakarondedzerwa zvizere kumusoro.

Kana paine chikonzero chinoita kuti mushonga hazvirevi kukunakira, rinogona kutsiviwa akadaro zvakafanana dzomuzana, sezvo "Barolo", "Emanera", "Geerdin", "esomeprazole", "Diaprazol", "Ortanol", "Nexium", " rabeprazole, "" Cavanero "," Sanpraz "," lansoprazole "," Ezolong "," Gasek "," Ultop "," Deksilant "" Pariet "," Zulbeks "," omeprazole "," Omelik "," Ozol " "Losek", "Omez", "Epicurus", "Omealoks".

Uyewo, kuti zvinodhaka "Proksium" zvinoreva kune zvinodhaka-anoreva zvakafanana 'Kontrolok "," Pantazi "," Panzol "," Panum "," Nolpaza "," Penta "," Pantex "," Pultset "," Ultera ".

Reviews kuti medicament

Zvinenge Wongororo vose mishonga vanoonekwa akanaka. Varwere vanoti mushonga "Proksium" unokurudzira nokukurumidza kuporesa erosions uye maronda, uyewo kudzivirira kukura wava kusvutazve.

Kana divi omunhu, anowanzodanwa kwakaratidzwa varwere vanosanganisira svoto uye nezvinetso chair.