Vitrification pamusoro oocytes: chii?

Mumakore achangopfuura, ezvokunambira kunze kwomuviri waamai muchangosangana iri kukura nokukurumidza. nzira iyi hakuchisina kuonekwa chinhu incredible uye dzisingambosvikiki kune vanhuwo zvavo. IVF rinoitwa munyika yose. Specialised mumarabhoritari uye makiriniki zvinowanikwa guta guru ose. Gore negore kutanga zvitsva, nani nzira kuti chokubereka. Kuburikidza kukura nzira iyi, mbereko vakaroorana vakawanda vakakwanisa kuva vabereki. Kazhinji kuunganidzwa mashoko pamusoro IVF, vakadzi kutarisana izwi akadai vitrification pamusoro oocytes. Iri izwi rinoreva munhu yerudzi rutsva muitiro unokubvumira kuvandudza pakati mazai.

Pfungwa yokuti "oocyte vitrification" - chii?

Kuti tinzwisise kuti chirongwa vitrification, unofanira kuva pfungwa ezvokunambira kunze kwomuviri waamai muchangosangana. nzira iyi zvinosanganisira zvakabudiswa hadzi utachiona masero (oocytes) kubva ovaries. Zvadaro pane avo kucheneswa uye muchangosangana dzisingaoneki anyatsoronga kana shamwari (kana murume haagoni kuva vana). Shure kwaizvozvo, mugove zygote anoiswa mukati uterine mhango. Vitrification pamusoro oocytes - muitiro yakafanana cryopreservation pamusoro oocytes. Zvisinei, zviri mberi. Under vitrification kwaireva nechando pamusoro saibva utachiona masero. Somugumisiro, mashoko oocytes inogona kuchengetwa kwenguva refu. Pasinei "yakagwamba nechando" mamiriro, masero Vitrified kuramba. nzira iyi ichakurukurwa kuva budiriro huru mune zvokurapa, nekuti nemhaka vakadzi vake vanokwanisa kuva mwana, kunyange kusavapo nhengo dzokubereka nadzo.

Chii chinangwa oocyte vitrification rinoitwa?

MuEurope, pfungwa dzakadai cryopreservation, vitrification tuvana uye oocytes, dzave kuzivikanwa kwenguva yakareba. Izvi zvinogona kuoneka kumadokero firimu iri mushonga. Munyika yaimbova Soviet Union, zvakare, vanachiremba vanoziva izvi mazwi kwemakumi emakore. Zvisinei, maitiro aya vava kuwanika varwere ichangobva. Kazhinji, vitrification kuti oocytes anobudiswa kuti ezvokunambira kunze kwomuviri waamai muchangosangana. Panguva nechando masero saibva nenzira yakadai mukadzi ane hukuru mukana vabudirire IVF. The batch mangé rokutanga oocytes vakasarudzwa kubva ovary havagoni kugadzirisa pasi. In ichi apiwa zvakabudiswa mashoko haina zvaida, sezvo pane masero kare Vitrified. Uyezve, pane zviitiko apo chena peya anokumbira ndichengetedze oocytes kwenguva refu. chinowanzoonekwa chinodiwa siyana pathological ezvinhu umo mukadzi haagoni kuva nevana. Uyewo, ane chikumbiro akadaro anotaura varwere vachigadzirira kuvhiyiwa kubvisa nhengo dzokubereka nadzo.

Under hapana pathologies vanokurudzira mazai vitrification?

Vitrification pamusoro oocytes uye anenge - a akabhadhara nzira kuwanikwa wose. Special zvairatidza nokuti haina, zvisinei, zvakakodzera chete dzakananga zviitiko. Izvi hazvirevi kuti vamwe vakadzi havagoni kuwana vitrified masero dzavo. Kunyange zvakadaro, pasina zvikonzero nechando kuti oocytes rakafanana mufashoni varwere vanokurudzira cryopreservation. Kakawanda vitrification ari kuitwa pasi zvinotevera ezvinhu:

1. Kugadzirira ovariectomy. oparesheni iyi kuitwa ovarian kenza nokufungirana kwayo kukura. chikonzero ichi hachisi kwakapararira zvikuru, sezvo kazhinji, gynecological kenza pathologies yabviswa uye dumbu.
2. Kutadza kuwana dzisingaoneki zuva yaunodya pamusoro oocytes. Nokuda kwechikonzero ichi, masero vanofanira chando sokuvapo mashoko pakusangana haangaregi isunungurwe.
3. Kenza chero localization. Pasinei apo ine kenza zvinoda radiotherapy uye kurapwa namakemikari (cytostatic) zvinodhaka. Mumwe nomumwe izvi nzira zvisingadiwi migumisiro pamuviri. Pashure kurapwa izvi kuparadza kwete chete kenza, asi masero utano, kusanganisira oocytes.
4. chido womukadzi kuva nevana vari kure kumwedzi Somuenzaniso, pashure kubereka. Muzviitiko zvakadaro Kashoma cryopreservation ndiyo zvibereko nokuti zai kuoma nechando ne nzira ichi chine musoro kwenguva. Naizvozvo, vanachiremba vanoti imwe nzira nzira - vitrification pamusoro oocytes.
5. Akadzokorora IVF, kana kokutanga zai haisi tsika. Muchiitiko chino, kupa vitrification kuti haana kutora mashoko katatu.

Vitrified oocytes anyatsoronga - chii?

Mune zvimwe zviitiko, rimwe chena hwemvura haakwanisi pamuviri, kunyange achibatsirwa ezvokunambira kunze kwomuviri waamai muchangosangana. Tiri kutaura vakadzi vane havachanyatsogoni kushanda gonads. Nokuti chinangwa ichi, mabhengi vaipa oocytes yakagadzirwa. Zvinosuruvarisa, havana kuwanikwa munyika dzose. saibva utachiona masero ose ane vitrified mamiriro, zvokuti inogona kuchengetwa. Zvairatidza kuti IVF uchishandisa anyatsoronga oocytes ndiwo:

1. Majini kutsunga zvokurwara - ovarian kukundikana syndrome.
2. Kusavapo oocytes nokuda zera zvechadenga dzokubereka nadzo (makore 40 uye vakuru).
3. Kusakwanisa kukurudzira ovulation nokuda zvomusejari kupindira pamusoro ovaries, mishonga chokupfeka.
4. Mukana mwana majini chirwere.
5. Akadzokorora IVF, haana kubereka zvibereko somugumisiro "chenhando" mazai avo pachavo.

Ndiani anogona kuva anyatsoronga oocytes vitrified: Zvinodiwa

Family Planning - ichi chisarudzo chakakomba zvikuru, kunyanya mune zviitiko apo vaviri anomanikidzwa kushandisa anyatsoronga masero. Usati wawana oocytes uye pasi pavo vitrification, chiremba akaita zvakawanda kuongorora zvose mukadzi uye nemabhuku anobudiswa. Mumwe ezvinhu hwakasimbiswa pamahombekombe nechando OVA, ndiye kusazivana. Kureva vabereki handizivi pamusoro nomupi ndiEzekieri. Zvinodiwa kuti vakadzi vanosarudza vitrified oocytes dzavo:

1. Age: makore 20-35.
2. Kushaya somatic uye nemagene zvirwere.
3. Zvinyoronyoro iziviswe phenotype.
4. Pamberi anyatsoronga mumwechete mwana wavo.
5. Kubvuma kuti zvakavanzika.

Chidobi kuti vitrification

Usati dzinotanga -oma hadzi gametes, akabata ovulation dzishande. Zvakafanira kuti oocytes dzakanga dzakawanda, pane mumwe. Pashure kwomuzvarirwo ichiibvira kunoitika munguva ovulation uye follicle zvibereko ovum mumwe chete. Kukuchidzira rinoitwa pamwe nemishonga. Next rinoitwa munhu pelvic Ultrasound. Kana ukaona kuti ovulation rave akaziva uye oocytes mu ovary yakakwana kwazvo, kuti IVF nzira iri mberi. Sero kukohwa rinoitwa pasi zvavo yokutindivadza. Kuponjesa tsono yakarova ikoko, pane oocytes, yose nzira rinoitwa pasi Ultrasound nhungamiro. Apinza mashoko kutanga inotevera Danho - ndichengetedze saibva oocytes. Vitrification pamusoro oocytes rinoitwa mune zvakasikwa kutenderera nokuda kufambira oma nzira. Ndiro huru kuchiitwa ichi kuchengetedzwa nzira.

Zvakanakira vitrification pamusoro oocytes

Sezvo vitrikatsii urongwa vakatanga zvishoma nezvishoma kutsiva dzimwe nzira ndichengetedze OVA uye tuvana zviri nani kwete chete kune vanachiremba asiwo varwere. Nzira iyi ine zvinotevera zvazvakanakira:

1. Mukana kumbosendeka pamuviri. Nokuti chokuti oocytes uye anenge muchando kwenguva refu (zvichienderana kusarudza womukadzi).
2. Kugona kuzodzosera IVF nzira pasina kutora mashoko ari wechipiri (kana kupfuura) nguva.
3. Kugona pamuviri pashure pakuvhiya dzokubereka omumuviri, nemwaranzi uye mishonga.

Chii chaiva musiyano vitrification uye cryopreservation mazai?

Sezvo chikazozikamwa, kwemasayendisiti kriokenservatsii uye vitrification pamusoro oocytes rakafanana chaizvo. Nzira Dzose zvakagadzirirwa kuoma nechando pamusoro oocytes uye anenge kuti tirambe chinhanho yavo. Kunyange zvakadaro, pane zvimwe kusiyana. Kazhinji, saibva oocyte cryopreservation sousingabatsiri. Izvi imhaka yokuti nzira iyi zvinosanganisira kunonoka oma zvinhu. Somugumisiro, nemvura cytoplasm dzikwanise chando crystals. Kuti kukuvadza sero rusvingo. Rakanakisisa nzira cryopreservation ose oocytes ndiyo vitrification. Percentage defrost kana kuita ayo yakaderera zvikuru, sezvo kutonhora mazai kunoitika anenge pakarepo. Ndizvo musiyano mukuru kubva cryopreservation vanoonekwa zvigadzirwa zvitsva kuti tirambe refu oocytes vari zvimwe ezvinhu. Kunonoka pamuviri nokuti anogona chete nzira vitrification nguva refu. Cryopreservation haripi nemigumisiro inogara yakadaro.

Sei IVF pashure vitrification pamusoro oocytes?

Oocyte vitrification rinoitwa kwose kwose. Freezing pamusoro gametes uye anenge kwenguva refu vaiita chete zvikuru unyanzvi mumarabhoritari nguva. Zvinenge zvose kiriniki pamwe zvokushandisa ichi ane pamahombekombe anyatsoronga oocytes vitrified. Kana mukadzi asarudza kuda pamuviri, masero vari thawed. Zvadaro shandisa ICSI unyanzvi rinoitwa muchangosangana. The zvichiguma embryo pasi culturing (3-5 mazuva) uye muchibereko kuva wakagadzirira endometrium. Masero yasara inogona nourume zvakare vitrified. Kana kuedza kudyara IVF nzira inodzokororwa.

Vitrification pamusoro oocytes: wongororo vanachiremba

Pari, vitrification uye kuchengetera oocytes uye anenge ari mabasa ose makuru maguta dzakabudirira mushonga. Kamwe nzira iyi akaedzwa uye rakaratidza pacharo, vanachiremba vanotaura nezvazvo chokwadi, kunzwisisa zvakanakira pamusoro vamwe (ambotaurwa) okuchengetera maitirwe ezvinhu mazai. Mari kuti -oma oocytes dzavo vakadzi vazhinji. The nzira inenge 12 zviuru rubles. mutengo uyu vitrification. Mari kuchengetera ari muchando masero ari rubles 1000 pamwedzi.