B12-kushaikwa kupererwa neropa: zviratidzo, zvinokonzera, kurapwa

B12-kushaikwa kupererwa neropa - chirwere asi ngozi, iyo chokuita nokuvhiringidzirwa kwomuzvarirwo ropa inotungamirwa pezvakaitwa kuitika pamusoro colour ose cobalamin kushayiwa pamuviri. Nhasi, vanhu vakawanda vanoda kuziva mibvunzo pamusoro zvipi pasi pokudzora kupererwa neropa achiperekedzwa zviratidzo uye sei chirwere.

Chii chinonzi chirwere?

Kutaura zvazviri, B12-kushaikwa kupererwa neropa anozivikanwa okuti siyana - kana pertsinioznaya megabloblastnaya kupererwa, pernicious kupererwa neropa uye Addison nehosha-Birmera. chirwere ichi pamwe kuderera kwenhamba masero matsvuku eropa, inova nokuda kushayiwa vhitamini B12 (cyanocobalamin). Zvinofanira kucherechedzwa kuti zvikuru nehanya kwokushayiwa fuma iyi haisi chete nemamiriro mumwongo asiwo etsinga rinenge iyo, chokwadi, chinoita kuti chirwere ngozi chaizvo.

Kazhinji, varwere vari akaonekwa B12, folic acid kushaikwa kupererwa, apo dzakaona kushaya folic acid. Zviratidzo chirwere pakutanga kurondedzerwa tichishandisa ichangopfuura - muna 1855, Chirungu chiremba T. Addison akanga marapirwo risingazivikanwi chirwere. Uye muna 1926, vaongorori W. Murphy, J. Will naJohani. Minot kwavo tsvakurudzo akaratidza kuti zviratidzo izvi zvikaramba zviripo, kana iwe kutaipa mune murwere zvokudya mbishi chiropa.

The kukonzera vhitamini B12 kushaikwa kupererwa neropa

Pakarepo zvinokosha kuziva kuti pane zvikonzero zvakawanda kwakadai kupererwa neropa. Vamwe vari chokuita nemararamiro, nepo vamwe - nokuchinja mumuviri.

• First unofanira kutaura inonzi muviri kushaikwa, izvo zviri kukonzerwa kukwana yaunodya vhitamini mumuviri kuburikidza chikafu. Somuenzaniso, chirwere ichi chinogona kuva pamusoro pakanyorwa achitsanya kana wakaoma vegeterianstva. In mucheche, chimiro ichi kupererwa neropa akaona chiitiko kuti amai vanoyamwisa anoramba mhuka zvigadzirwa.
• Mune dzimwe varwere pane kutyora kwagara kubvisa cyanocobalamin.
• Zvinokonzera B12 kushaikwa kupererwa neropa zvinogona nokuda kwokushayiwa vanonzi mukati chinhu Castle. Ichi kunyanya kunzwisisa fuma kuti asunungurwa intestinal mucosa, zvakabatana cyanocobalamine uye kunopa Absorção de Água kwayo. Uyewo, kushaya fuma iyi inogona kukonzerwa nevamwe vachiberekwa anomalies, uyewo autoimmune zvirwere. Uyezve, kushaya Castle chinhu vakachengeta apo siyana STRUCTURAL kuchinja mudumbu, akadai gastritis, kuvhiya akavhiyiwa uye zvichingodaro. D.
• zvinokonzera njodzi kunogona kunzi, uye zvakasiyana-siyana kuchinja chimiro intestinal zvinyama kuti kuchengetwa pamberi namamota, kana achikura somugumisiro kuvhiya resection of bowel.
• Kubvisa bowel basa dzinosiyana pamberi dysbiosis, sezvamakaropafadzwa microflora nziyo achinja.
• Mune zvimwe zviitiko, cyanocobalamin, ari anwa zvokudya wefodya nemamwe "vomumuzinda" zvomudumbu ezvinhu akadai pathogenic utachiona kana nehonye.
• Zvinhu Risk ingasanganisira chiropa uye chirwere cheitsvo uyewo dzavaigara zvinowanzooneka kuchengetwa kuwedzera yavaive vhitamini B12 kana kushandiswa kwayo kukwana.
• Deficiency anogona kuva ari chiitiko kuti zvinyama kana nhengo kupinza yakawandisa yacho vhitamini. A yakafanana chiri wakacherechedza Somuenzaniso, pamberi munhu kukurumidza kukura kenza. Zvinhu Risk zvinosanganisira kuchinja kwemakemikari omuviri uye vamwe kwemakemikari anobudiswa zvinetso, uye zvirwere chokuita kurasikirwa vanoshingaira masero matsvuku eropa.

The pathogenesis chirwere

Sei B12-kushaikwa kupererwa neropa? The pathogenesis chirwere ndiyo akarondedzera dzinokosha mashandiro anoita cyanocobalamin zvakananga. vhitamini ichi inoita basa rinokosha nedanho hematopoiesis. kushaikwa kwayo kunoita kuti mamiriro inozivikanwa "megablastoz". Zvinonzi pamwe kuunganidza guru siyana maplatelet uye ropa masero machena, uyewo kuparadzwa kwavo vakurumidze mu mumwongo.

Uyezve, vhitamini B12 chinhu cofactor iri kiyi Exchange siyana kuti zvinokosha muupenyu masero etsinga. Ndokusaka kubva ayo dhefisiti tsinga anotambura.

B12-kushaikwa kupererwa neropa: chirwere zviratidzo

chirwere kwakadaro kubatana vakawanda zviratidzo, izvo kazhinji aibatanidza mumapoka mikuru mitatu.

Chokutanga, ngatimbotaura pamusoro neta neta chirwere kuti anova tikafunga kuderedza uwandu masero matsvuku eropa. Pakutanga, varwere chokunyunyuta pamusoro zvikuru simba, kukurumidza kuneta uye anyatsoona rutapudzo vaita. Sezvo chirwere mberi ikoko neapo chinovapo tinnitus uye dzungu, uye dzimwe nguva kunyange kutofenda. Sick vanhu onawozve pakuonekwa "enhunzi" pamberi ake. Zviratidzo kupererwa neropa zvingasanganisirawo mwoyo palpitations uye kwazvo kupfupika mweya kuti kuitika kunyange kuchangotanga chaiko nesimba. Dzimwe nguva pane kusingafadzi, kubaya marwadzo ari pachipfuva.

Chokwadi, aine dhefisiti vhitamini akacherechedza uye zvinetso zviri zvomudumbu hurongwa. Zvikurukuru, varwere ndaona zvinoshamisa kuderera kudya, uye somugumisiro, muviri uremu. Inodzokororwa svoto uye kurutsa kuuyawo muupenyu hwomunhu yakawanda kuzvuzvungudza. Mukuwedzera, zvingangove kutyorwa rwecheya - kazhinji zviri refu kupatira. Very maitiro uye vanoonekwa kusandura mutauro, ane nomumativi ari ndokudzora uye anova piriviri uye dzimwe nguva naka Hue.

Chokwadi, izvi hazvisi zvose kuchinja pematanho B12-kushaikwa kupererwa neropa. Zviratidzo kuoneka uye tsinga. Pakutanga pane kukundwa ari peripheral tsinga. Varwere yakashuma risingafadzi tingling mumaoko nemakumbo, uyewo duku chiveve. Zvishoma nezvishoma tsandanyama simba. kuchinja nezvishoma mune gait iri kuchengetwa chokuita kuomarara of makumbo - zvinova zvikuru kugadzikana.

Refu kushayiwa vhitamini B12 kunotungamirira musana nehana, uye ipapo muuropi. The zviratidzo zvinetso zvakadaro zvinogona zvakasiyana. Somuenzaniso, kuvadza fibers ari musana, kazhinji kunotungamirira kune imwe kurasikirwa nehanya - murume haachatyi anorwadziwa vibrations ganda (kazhinji kunokanganisa ganda riri makumbo). Vamwe varwere vave nokugwinha. Asi kushatirwa, chin'a chinja manzwiro, kusagadzikana omumwe ruvara anoratidza uropi. Pasina yokurapa, murwere anogona vanowira pakoma.

marudzi chirwere

Chokwadi, pane mazano kupatsanura pakati chirwere anoverengeka. Zvakakosha kuziva kuti mune mushonga ano B12-kushaikwa kupererwa neropa rinogona mhando mbiri, zvichienderana zvinokonzera:

• The chikuru chimiro chirwere inowanzopiwa chokuita zvimwe nemagene zvechadenga muviri. Zvakanga zvakadaro B12-kushaikwa kupererwa neropa nevana vacheche kunoitika kakawanda.
• The chimiro yechipiri chirwere ikabuda atova muitiro kukura uye upenyu murume, achifuridzirwa zvinhu zvekunze kana zvemukati ezvinhu.

kupererwa neropa rwakazara

The chikuru Zviratidzo chirwere vari zvakananga novimba padariro kwayo kukura. The kwokuomerwa ezvinhu murwere kazhinji akatara kwakavakirwa nhamba erythrocytes (matsvuku masero) muropa. Zvichienderana pamusoro nhamba iyi, pane matanho matatu chirwere:

• In munyoro kupererwa, matsvuku eropa count anoda kubva 90 kusvika 110 g / l.
• Average nekuomarara chimiro kunoratidzwa chinokosha kuderera kwenhamba masero matsvuku eropa - kubva 90 kusvika 70 g / l.
• Kana murwere matsvuku eropa count 70 g / L zvichidzika, zvino yava kwazvo chimiro B120-kushaikwa kupererwa, izvo ngozi kwazvo utano uye kunyange upenyu.

chimiro ichi kupererwa neropa sei nengozi? zvinogoneka yematambudziko

Kupererwa, vhitamini B12 kushayiwa pasina nenguva kurapwa kunogona kuva nengozi zvikuru. Sezvambotaurwa, zvikurukuru kushaya fuma iyi inokanganisa tsinga. Matambudziko kwakadai kupererwa neropa anosanganisira musana uye peripheral tsinga. Uyewo, nenyonganiso aya achiperekedzwa kusanzwa uye tingling mu wamativi, dzizere uye haasaruri kurasikirwa manyawi, fecal incontinence kana incontinence.

Tikafunga chisingaperi cyanocobalamin kushaikwa Zvinoipisisa muviri wose - kungaita zvakasiyana siyana zvirwere netsvo, mwoyo uye nedzimwe nhengo. Dzimwe nguva, pakati unopinza zvinoderedza uwandu masero matsvuku eropa kuva uropi hypoxia, zvichiita kuti pernicious pakoma.

Kana ukatanga kurapwa vachiri Danho, ipapo zvose pamusoro matambudziko zvinogona kudziviswa. Late akatanga mushonga anogona kubvisa vhitamini kushaikwa, asi, nhamo, kuchinja tsinga iri kare kusingarapiki.

Modern nzira nechirwere

In pamberi pamusoro zviratidzo unofanira zvachose kuona chiremba. Pashure pezvose, chete mazvikokota anogona zvakarurama kuziva chirwere. Kutanga anoitwa nhau zvokurapa. kazhinji B12-kushaikwa kupererwa neropa hwapedyo pasi pokudzora siyana zvimwewo zvinoitika, saka chiremba kubvunza ruzivo pamusoro murwere upenyu, simba rake, uye zvichingodaro. D. Mune ramangwana, anofanira chaiko bvunzo. In varwere yakafanana chirwere, sezvinoita mutemo, unogona kuonekwa ganda rakachenuruka. Kazhinji pane kuderera BP uye palpitations.

Chokwadi, gare gare vakatevera vamwe zveBhaibheri, iyo unogona kuona kana pane B12-kushaikwa kupererwa neropa. A bvunzo nehosha kwakadaro ropa vanoratidza kuderera uwandu erythrocytes vavo kumadziteteguru (reticulocytes). Pamwe ichi pane kuderera platelet count. Chokwadi, akaderedza padanho Chizenga muropa. Nemakemikari Kuongororwa ropa anogona kupa mashoko anokosha. Kana siyana kupererwa neropa pane kuwedzera ropa kwevari bilirubin nedare.

Chirwere kubva B12-kushaikwa kupererwa neropa zvinosanganisira dzimwe nzira. Zvikurukuru, mwongo rinoitwa fenzi (kakawanda vakatakura sternal ponji) yokutsvakurudza murabhoritari. Mukuwedzera, murwere maoko pamusoro Analyses ose weti uye mutsvina yadzo. Anoratidza electrocardiography, electroencephalography, computed tomography, uye dzimwe nguva vamwe dzimwe nzira - miedzo izvi zvinodiwa kuongorora mwero kukuvara mamwe nenhengo dzawo, uyewo kuona chikonzero kupererwa neropa.

B12-kushaikwa kupererwa neropa: kurapwa

Chiremba anogona kuita zvinobudirira kurapwa chete pashure zvizere muviri ongororo. Saka chii kurapa zvinoda B12-kushaikwa kupererwa neropa? Treatment rinotanga kubviswa runotikurudzira chikonzero chacho. Somuenzaniso, apo dzakabatwa varwere helminthic infestations antiparasitic yomuchipatara uye pamberi bundu - kuvhiyiwa.

Uyezve, zvinokosha kuti kuripa kwaiva cyanocobalamin. Mumazuva vhitamini mhinduro yokutanga shoma iri jekiseni intramuscularly. Nokuti avhareji akura dose nezuva anobva 200 kusvika 500 micrograms. In ezvinhu akanyanyisa uwandu zvinodhaka ichiwedzerwa kusvika 1000 mcg - zano vanoomerera mazuva matatu. Paaizosvika wakadzikama kuvandudzika kuderedza dose kuti 100-200 MG - majekiseni dzinopiwa kamwe pamwedzi kwemakore 1-2.

Sezvingatarisirwa, zvinokosha kuita zvakanaka kudya kuti unosanganisira zvokudya akapfuma cyanocobalamine uye folic asidhi - ndiko kunonyanya pechiropa, nyama uye mazai.

Zvakakomba kupererwa neropa zvinoda kukurumidzirwa muzadze matsvuku eropa count. Nokuti chinangwa ichi, varwere vari masero eropa matsvuku kubva vakapa ropa. Chete nzira kunokosha kana neta neta pakoma.

Maererano nenhamba, kuti fungidziro varwere rakanyatsojeka zvakanaka. Kunze vaya zviitiko apo munhu anotsvaka kubatsira chakakomba zvikuru ezvinhu, sezvo kudzorera vawirwa nenjodzi kuti tsinga hazvibviri chete.

Pane nzira dzinoshanda muzvidzivirire?

Sezvaunogona kuona, B12-kushaikwa kupererwa neropa - chirwere aiva nengozi. Saka zviri nyore zvikuru kuti kuedza kudzivisa nayo. Zvino iyi, zvakanaka kuumbwa Kudya kunokosha chaizvo. Chenjerai kuti zvokudya akapfuma cyanocobalamine vakapinda kugara Muterere yenyu. Zvikurukuru, vhitamini B12 rinowanikwa mazai, nyama, chiropa nezvinogadzirwa nomukaka.

zvirwere zvose zviri nemudumbu nguva kupindura kurapwa - zvinokosha kuita zano chiremba uye musarega mishonga yavo. Kubva nguva nenguva Zvinokurudzirwa kuzvidzivirira chipimo kutora multivitamin zvivako (mwedzi mitanhatu ose).

Pashure pokuvhiyiwa kubvisa chikamu ura kana mudumbu chiremba vanosungirwa kugadza murwere cyanocobalamin gadziriro iri rakakodzera dose.