Chii chinonzi "RNA yehutachiona hweH hepatitis C isingaone"? Kuongorora kweRNA yeHepatitis C Virus

Munhu wose anogona kutapukirwa nechipatara C. Vanhu vazhinji vanogara nehosha iyi kwemakore mazhinji uye havazivi kuti vane nzira mukati, izvo zvichakurumidza kana kuti zvinotungamirira kumigumisiro inosuruvarisa. Vanhu vakadaro vanoshingaira kuuraya vamwe, uye kuwanda kwekuparara kunoramba kuchiwedzera. Kuti kuderedze zviratidzo izvi, munhu wose anofanira kutora mutemo wenguva nenguva kutora kuongororwa kwehepatitis C, kunyanya kana ari pangozi.

Nhoroondo shoma pamusoro pehosha

Hepatitis C virus (HCV) ine molekemu yeRNA inotakura genetic ruzivo uye mapuroteni chaiwo achibatana nemuviri womunhu. Inoparidzirwa kunyanya kuburikidza zvepabonde uye neropa. Mune zvimwe zviitiko, nzira yekuendesa mberi (kureva, kubva kuna amai kuenda kumwana) inoita.

Inopinda mumuviri, inogadzika mumasero akasiyana-siyana eropa (neutrophils, monocytes, lymphocytes) uye chiropa (hepatocytes).

Kuvhiringidza kwehutachiona kuripo kusina kwezviratidzo zvechikamu chakaoma. Iyo inopfuurira inopinda muchirwere chisingaperi chisinganzwisisiki uye inononoka kuona zvayo zvinoparadza.

Migumisiro

Kubva pakutanga kwekupindira kupinda mumuviri weRNA wehutachiona hweH hepatitis C kusati kwaonekwa kwekutanga zviratidzo zvinogona kuenderera kwemakore akawanda, dzimwe nguva makore makumi maviri nemashanu kana kupfuura. Kubuda kwekunyunyuta kunofananidzwa nechimiro chekushaya hanya chehepatitis C, apo chiropa chave chave chakakanganiswa. Vazhinji vevarwere vanoonekwa kuti vane hutachiona hunotevera:

• Cirrhosis;
• Necrosis;
• Benign cysts;
• Oncology.

Isati yatanga kukura kwezvinetso, murwere angatora gorosi duku, iyo kazhinji isingakoshesi.

Ndiani ari kuongororwa

Kuongororwa kwetachiona hweH hepatitis C kunoratidzirwa kuvanhu vanowanzosangana nehutachiona. Iri boka rinosanganisira:

• Zvinodhaka zvinodhaka;
• Vanhu vane hupenyu hwepabonde hwepabonde;
• Vose vanoita zvepabonde zvisina kudzivirirwa, kunyanya newavo vatsva;
• Vafudzi vematoto, kuboora, saroni dzakanaka (vabati vehodzi);
• Vanhu vakawana rubatsiro rwekuvhiya (kusanganisira kubereka, dental pathology);
• Amai vevana vakaberekerwa gore ra1990 (chokwadi ndechekuti panguva iyoyo chirwere chisati chaonekwa, saka, apo kuwedzerwa kweropa, vakadzi vakadaro vaitapukirwa nehutachiwana);
• Vana veamai vanorwara;
• Hama neshamwari dzepabonde dzevanotapukirwa;
• Varwere vane zvirwere zvisingaperi zvisingazivikanwi.

Nhamba yacho yakazara kwazvo, saka vashomanana vanogona kutaura nechivimbo kuti njodzi yehutachiwana ndeye zero.

Kumba kuongorora

Vanhu vazhinji vanoda kuongororwa kutsvaga kweRNA yehutachiona hweH hepatitis C, asi usabvunzurudza chiremba nekuda kwenyara, kusava nenguva, kusafarira zvipatara, nezvimwewo.

Kugadzirisa chinetso kunobatsira nyore kuongororwa uchishandisa chirongwa chinokosha nokukurumidza (ELISA). Munyaya iyi, nzira yehutano inoshandiswa iyo inongorongedza chete iko kwekuvapo kwezvirwere kune utachiona.

Mabasa pamusoro peshoko rekuedza kuti aone kusununguka, asi sezvinodiwa kuongorora zvinoda ropa:

1. Mune chigadziro chine plastiki strip (chengetedza kuongorora kwechigumisiro) kune lancet inokosha inobvisa munwe nechokuno chete pane bhatani.
2. Nekubatsirwa kwepipette, ropa rinowanikwa mune imwe nzvimbo inokosha, uye mushure memaminitsi gumi nemashanu kupindura kunogona kuongororwa.
3. Mabharari maviri anoratidza chiitiko chakanaka, chimwe-chikonzero chakaipa. Kuonekwa kwechipiri chepachivara panzvimbo yekutarisa kunoratidza kuvepo kwechirwere, asi kuiswa kwezvirwere muropa zvakanyanya kuduku.

Kana chirwere ichi chave chaonekwa, unoda kuenda kunechiremba kuti uwedzere kuongorora.

Nheyo dzemitemo yekuona RNA yevhirwere yeHepatitis C

Nemigumisiro yakadaro kunokosha kuongororwa nehutachiona hwehutachiona uye hepatologist uyo anongoronga zvimwe zvidzidzo.

Chinhu chikuru pakuita shanduko dzinotevera ndekuzarura kuti genotype inowanikwa hepatitis yakabatana, uye kuti ione muyero wayo muropa. Kubva pamashoko akawanikwa, mamwe marapirwo achawedzerwa, sezvo marudzi ese akasiyana kubva kune mumwe uye anogona kuita zvakasiyana nemishonga. Mukuwedzera, microorganisms vanogona kuzvivanzira pachavo.

Aina dzekutsvakurudza

Kana uchitarisa HCV, imwe yenzira dzinotevera dzinoshandiswa:

1. PCR. Muchiitiko ichi tinenge tichitaura pamusoro pezvinyorwa zvemajini zvepathogen.
2. Kuongororwa kuongororwa kwehutachiona hweH hepatitis C (r-DNK, TMA). Kuongorora kwakadaro kunoitwa mushure mekusimbiswa kwehupo hwemagetsi mumuviri. Inonziwo chirwere chetachiona. Iko inokubvumira kuziva nhamba yezvirwere zvepachigoni mu 1 meri yeropa. Kubva pane zviratidzo izvi zvinotora nguva yekurapa uye chiyero chekupererwa kwevarwere. R-DNK inoedza kuongorora mukati mema 500 ME, uye TMA pa5-10 ME. Nzira mbiri idzi dzinofungidzirwa sezviri nyore uye dzinodhura.
3. Genotyping. Inoitwa mukutendeuka kwekupedzisira uye inokubvumira kutsanangura kuti ndeipi mhuka iyo inozivikanwa chirwere ichienderana.

Kuongororwa kwemigumisiro

Kana kuongororwa kweRNA yehutachiona hweH hepatitis C yakapa chibereko chakanaka neCPR neE ELISA, kuongorora kunosimbiswa. Zvisinei, chiitiko chakaipa hachisati chavimbisa kusava nechirwere. Zvinosuruvarisa, izvi zvinowanzoitika, nokuti reagents nekunzwisisa zvakasiyana siyana zvinogona kushandiswa mukugadzirisa.

Vakawanda vanofarira kuti zvinorevei "RNA yeirwere ye hepatitis C haina kuonekwa." Chiratidzo chakadaro chinogona kuratidza kusavapo kwechirwere ichi kana kuti zvishoma. Semuenzaniso, PCR 200 ME / ML ichapa chikonzero chenhema kana murwere ane nhamba shoma yemavhidhiyo. Izvi zvinogona kuitika nehutachiona hwekupedzisira kana panguva yekurapa.

Kazhinji, murwere haafaniri kuva nemashoko akadai, sezvo izvi zvinofanirwa kuverengerwa nechiremba anoenda.

Kuzivikanwa kwetachiona hweH hepatitis C mukudzidza kwakawanda kwe 400,000 IU uye vamwe vanoti hutachiona hahusi muropa chete, asi hunowedzerawo huzhinji, huchibata vamwe. Kana chiratidzo chacho chiri pedyo ne800 000, izvi zvinoratidza chikamu chakaoma uye chinokanganisa kuora kwemasero emuropa.

Kunyange zvazvo pano maonero evanyori akasiyana. Vamwe vavo vanoti hakuna hukama nehuwandu hwekuwedzera kwezvirwere uye nhamba yemakopi ehutachiona.

Varwere vakadaro vanofanira kunge vakangwarira mukukurukurirana nevadiwa vavo.

Kuwedzera kuongororwa

Kamwe apo chirwere cheHitpatitis C chakatarwa, murwere angagoverwa dzimwe dzidzo, kusanganisira:

• Kuziva hepatitis B;
• Kurondedzeredzwa kweropa uye urini;
• Biochemistry;
• Ultrasound of the abdominal cavity;
• MRI kana CT yechiropa (maererano nezviratidzo).

Mushure mokugamuchira ruzivo rwese runodikanwa, chiremba anonyatsoongorora zvigumisiro, hupenyu hwehutano hwemuurwere, uye anobva amusarudzira mumwe mutemo wemishonga.

Nekuona nguva yakakodzera, kuora kwechiropa kazhinji hakusipo.

Nzira dzokurapa uye mazwi

Nguva yehutano inobva pane genotype. Kusvika iye zvino, marudzi gumi nematanhatu anozivikanwa ayo 6 anowanikwa kakawanda. MuRussia, inonyanya kukosha ndeye 1, 2, 3-rd rudzi.

Makore mashomanana apfuura, hepatitis C yaiva chikamu cheboka rezvirwere zvisingaregi. Kurapa, kwakaitwa zvikurukuru ne-interferons, kunogona kuchinja zvikuru mamiriro emurwere, asi kwete kuchirapa zvachose.

Kubudirira mukurapa kwechirwere kwaiva mishonga ye "Sofosbuvir", iyo yakaonekwa mu pharmacies pasi pezita rakasiyana rekutengeserana "Sowaldi". Kusvika iye zvino, pane dzakawanda zvakasiyana-siyana zvekushandisa zvinobudirira:

• "Viropak";
• "Gratiziano";
• "Hepzinat";
• "Gepetavir."

Kazhinji ivo vanoregererwa zvakanaka nevarwere, asi mune dzimwe nhamba, pane:

• Headache;
• Nausea;
• Insomnia;
• Kuora kwekudya;
• Kushungurudzika;
• Migraines;
• Kuora mwoyo;
• Manzwiro ekuoma mumuromo;
• Chipfuva chepfu;
• Kurasikirwa kwebvudzi.

Dambudziko roga rokutapwa kwakadaro nderokudhura kwakanyanya (pamwero we10 000-12000 rubles pamapuranga), ayo, zvichienderana nemishonga yakasarudzwa, inogona kusiyanisa zvishoma kana zvishoma.

Kudzokorora zvakare

Mushure memugumo wemishonga, inogara kubva pamasvondo 12 kusvika ku24, murwere achagoverwa kechipiri kuongororwa kwehupo hweRNA muropa.

Muchiitiko ichi, zvichave zvakakodzera kushandisa nzira yacho nechepakati pachidziro chekushushikana, sezvo mushure mokunge kuonekwa kune zvinodhaka kuwanda kweHCV kunogona kusakanganiswa. Muchiitiko ichi, kurapwa kunoda kupfuurira.

Chikonzero chisina kunaka ndekushayikwa kwoutachiona hweHepatitis C, apo pasina RNA yepathogen yakaonekwa. Kudzidza kwakadaro kunoda kuitwa kazhinji kazhinji (panguva pfupi) kuti uve nechokwadi chokuti kurapwa kwakabudirira.

Kudzivirira

Kune vose vakagamuchira kurapwa kwenguva refu uye kunodhaka kwe hepatitis C, zvakakosha kuyeuka kuti kwaari muviri hauna kukudzivirira utachiona, saka zvinowanzoitika zvirwere zvinogona kuitika.

Ichi chirwere chiri nyore kudzivirira pane kupora. Kunyatsozvidzivirira pachavo kubva pane zvinogona kuitika hazvizoshandi, asi kuitira kuti musadaro musabvunza kuti zvinorevei "RNA yehutachiona hweHepatitis C inowanikwa," zvinotevera zvinodzivirira zvinofanira kuonekwa:

• Usashandisa zvimwe zvinhu zvehutsanana hwevanhu (razors, scise, dental floss);
• Dzivisa zvepabonde zvisina kudzivirirwa;
• Kushanyira mazinyore, maroni (kunaka, tattoo, nezvimwewo) chete nemukurumbira wakanaka;
• Dzadza nemabhanhire kana mabhanhire ose maperembudzi eganda;
• Kana zvichibvira, dzivisa kusangana nemunhu ane utachiona.

Forecast

Yakafanirwa chirwere ichi chakaonekwa, zviri nani kurapwa kuchave. Kazhinji, kana kusavapo kwekukuvadza kune nhengo dzomukati, hepatitis C inoporesa zvachose uye pasina migumisiro.

Kana hepatitis C isiri kurapwa, achakurumidza kana kuti gare gare kutungamirira ku-cirrhosis kana kenza yeropa. Izvi zvinogona kuitika kunyange makore 30-40 mushure moutachiona hwehutachiona.

Chirwere chepirhosis nemhaka yehepatitis C chirwere chisingaperi, chisingaregi. Mune matanho ekutanga iwe unogona kuidzikisa pasi, mumhosva isina hanya, munhu anogona kuponeswa chete nechiropa chekupemha.

Mushure mekudzidza pamusoro pezvakanaka zvinokonzera hepatitis C, haufaniri kutya pakarepo. Kutanga, iwe unofanirwa kutarisa mamiriro ehuvha hwako uye wotanga kurwisana nehutachiona uye hukama hwehutano hwakanaka. Mishonga yakareba uye inodhura, asi inopa murwere mukana wehupenyu hurefu uye hwakanaka.