Chii chirwere Addison raMwari?

chirwere Addison raMwari apo atadze kushanda zvakanaka pamusoro adrenal cortex. chirwere ichi chiri chirwere mune varume nevakadzi, kunyanya repakati (30 kusvika 40 years). Ihosha chisingawanzowaniki, iyo rinonyoreswa mune munhu imwe 100 zviuru. Population. Addison Biermer chirwere anogona kuva nokuda autoimmune urongwa, zvirwere (njovhera, tiibhii uye fivha adrenals), uye muna amyloidosis uye nyanyisa anomera. Muna 70% wevarwere, hosha kunoitika somugumisiro yezvikanganiso iri zvirwere (antibodies vari kutanga kutora muviri masero kuti mitumbi vatorwa, uchirwisa uye vakavaparadza). With kuparadzwa adrenal cortex masero zvinoderedza kwetunhu gluco uye mineralocorticoids (cortisol, 11-deoxycorticosterone, aldosterone). Masayendisiti dzakaratidza kuti glucocorticoids inodzora siyana nokukanganisika pezvakaitwa mumuviri (inodzora BP, jekiseni wevasungwa, rinobatanidzwa murau mapuroteni usage, lipids uye makabhohaidhiretsi).

Gipokortitsizm kazhinji kuchengetwa varwere kubatwa mahormone ari adrenal cortex. Kazhinji, ari etiology chirwere yasara USINGAZIKAMWI. Adrenal insufficiency Classified kupinda nesekondari. Primary kukundikana ikabuda pokukundwa adrenal zvinyama uye yechipiri - nokuda kukwana kweiyi adrenocorticotropic kemikari.

Addison raMwari Disease Zviratidzo

Clinical zviratidzo chirwere kunokonzerwa kushayiwa ari Muviri chicherwa uye glucocorticoids. Zvikuru maitiro zvinhu zviri utera, hypotension dzinoparadzana gastrointestinal (kuda kurutsa, kurasikirwa kudya, kurutsa, kupatira, manyoka izvo kazhinji chakatsiva). Vamwe varwere hypochlorhydria.

chirwere Addison kunoperekedzwa nokuda yakawedzera kushatirwa kana akaora mwoyo, kakawanda nomusoro uye kushaya hope. X-ray pechipfuva rinoratidza vasanyanye kukura mumwoyo. The unonzi, electrocardiograph anonyora zviratidzo hyperkalemia (mukuru potassium wevasungwa muropa). Ruvara rweganda hazvirevi Zvisinei kuratidza kwokuomerwa hosha,, kuwedzera kana kutapudza payo mishonga uchapupu pamusoro kubudirira kuchirapa chiito.

chirwere Addison inozivikanwa nokuva kwakabva yechipiri zviratidzo zvishoma kwazvo. Very Kashoma maperembudzi pachena pacharo pasina pigmentation (saka musoro "chena Addison"). The chikuru chinokonzera chirwere ichi ndicho tiibhii adrenals. Pasina zvakakodzera kurapwa chirwere Addison Matambudziko. Clinical zviratidzo zviri yakakura: svoto, kurutsa, manyoka, BP anodonhedza hasha, kuwedzera wevasungwa kuti potassium muropa. Mugore peripheral ropa residual Nitrogen kunowedzera nhamba masero matsvuku eropa, hemoglobin. Naizvozvo, kana panguva yedambudziko addisonicheskogo murwere haripi kundibatsira, akafa pamwechete zviratidzo renal uye zvemwoyo chirwere.

Chinonyanya kukosha rabhoritari parameters kuti chirwere ndiye zviri 17-OCS mu yeplasma uye 17-KS ari weti, uyewo vasanyanye muropa shuga yomuropa. Morphological kuzviongorora ropa anoratidza lymphocytosis, eosinophilia uye ESR kunonoka.

chirwere Addison iri kusiyaniswa zvinotevera zvirwere: cheshuga yendarira, pellagra, chepfu arsenite uye Bismut Argentum. The chirwere Kazhinji ane chirwere nzira chete nguva nenguva peaking. Addison Biermer chirwere kwokuomerwa pakutsvaga kwokuomerwa mikuru nezviratidzo chirwere, uyewo maererano nokuwanda mishonga kuti zvinodiwa kudzikamisa adrenal insufficiency.