Drug "Arlette": mirayiridzo kushandiswa, contraindications, akafanana uye wongororo

Kamwe kukura nyore kuti penicillin rakava mushonga wandei kwemabhakitiriya zvirwere kuti vanhu kakawanda akafa. Kubvira ipapo, vanhu varinani kupinda mumwe chemakore, uye kwakasimbiswa dzinoverengeka wezvokurapa antibacterial zvinodhaka sezvo munoremekedza chakarondedzera, uye vane hanya chero chaiyo tisawirirane ose microorganism. Chimwe chishandiso ndehwevakadai "Arlette". pakushandisa ichi mishonga gwaro rine nzwisisika ruzivo pamusoro zvose ehupfumi dzayo.

The Zvinoumba antibacterial mumiririri

The huru zvinoriumba ndivo amoxycillin trihydrate (dzaona sezvo amoxicillin zvichibvira mavhoriyamu 250, 500, 875 MG) uye potassium clavulanate (vhoriyamu - 125 MG, inobva clavulanic acid). Rokuti wokutanga anonzi akatevedzana semisynthetic kuti penicillin, dzinoratidzwa pose munda antibacterial basa. Chikuru chezvinonhuwira kuti medicament wechipiri ane kusingarapiki inhibitor kuti Beta-lactamases.

Uyezve, vakawanda ebetsero zvinoriumba kuva mushonga "Arlette". Mirayiridzo yokushandisa, rondedzero rekugadzirira angasvikira pfungwa vatengi kuti varipo vari murwiyo kamari samolecular uremu makirisito povidone, pregelatinized starch, karusiyamu stearate, microcrystalline cellulose uye talc. Uye kwete kuti ndicho zvose.

The casing aumbwa asingaurayiwi hypromellose, propileglikol uye polyethylene glycol 4000 (macrogol kana 4000), titanium dioxide. Uremu rimwe piritsi, "Arlette" (mirayiridzo kushandiswa rine ruzivo urwu) 600 1100 kana 1600 MG.

pharmacodynamics

Sezvambotaurwa, "Arlette" chinhu chisinganzwisisiki pane amoxicillin uye clavulanic acid. Ekupedzisira siyana mudanga inactivated kunzwisisa pamwe Beta-lactamases (kwemabhakitiriya makemikari, chikuru kushanda riri tidzivise Beta-lactam nemishonga, inonyanya kushandiswa inorwisa utachiona Kurapwa - cephalosporin, kuti penicillin uye zvichingodaro N..). Beta-lactamases vane basa pakusika anosimbirira kushorwa chambotaurwa nezvacho zvokurapa namano.

By pacharo, clavulanic acid, sechivako chiri akafanana Beta-lactam madhiragi, dzinoratidzwa asi simba pachake mano antibacterial. Kunyange zvakadaro, kuvapo asidhi mukugadzirwa "Arlette" inoshora kuparadzwa amoxicillin uye anowedzera kuwanda kwayo antibacterial nezvaanogona, kusanganisira mairi utachiona uye tupukanana tusingaoneki, izvo pasi pomureza ezvinhu husingakwanisi nezvaizoitwa amoxicillin, dzimwe nzira nemapoka penicillins uye cephalosporins.

Inorwisa mabhakitiriya "Arlette" mirayiridzo kushandiswa ari medicament anoita yakafarikana chokupfeka nzvimbo. Iye rinoshanda pamusoro kubatwa amoxicillin utachiona (kwete dzakakudzingai avo kuti synthesize Beta-lactamase). Izvi zvinosanganisira zvakawanda giremu-akanaka uye giremu negative Kurovedza uye anaerobic utachiona.

Zvairatidza "Arlette" zvinoreva

Field kushanda muna ari antibacterial mumiririri panzvimbo yakakura, zviri vanobudirira dzinoverengeka dzakasiyana utachiona Mabviro. "Arlette" mirayiridzo kushandiswa mvumo yokushandisa kugadzirisa matambudziko rokumusoro kufema turakiti uye yokumusoro kufema turakiti. Akanyanya tiri kutaura pamusoro chakasimba uye chisingaperi siyana sinusitis uye otitis nhau, mumwe tonsillitis, pharyngitis, abscesses iri retropharyngeal munharaunda. The kubatsirawo munhu medicament nokuda kurapwa kwezvirwere ane nechepazasi kufema ezvinhu, izvo zvinosanganisira bronchitis (chisingaperi uye rikwanise, achiperekedzwa kwemabhakitiriya superinfection) uye nemabayo.

Zvisinei, haisi zvose munzvimbo Arlet rikashandiswa. Mirayiridzo yokushandisa, mishonga Rondedzero akashuma kubudirira kwayo pakurapa zvirwere genitourinary ino uye pelvic zvomukati. zvirwere zvakadai zvinosanganisira pyelonephritis, prostatitis, urethritis, endometritis uye kwemabhakitiriya vaginitis, septic pamuviri, mwandabvu uye m. P.

Uyewo Hune zvahunoita mushonga pakurapa ganda uye akapfava zvinyama zvirwere akasiyana-siyana (abscesses, cellulitis, erysipelas, impetigo, muchikuvadza nomumativi apiwa utachiona dermatoses chirwere) chokwadi. "Arlette" rinogona kushandiswa pakurapa pfupa uye connective munyama, biliary turakiti prolechivanii (cholecystitis, cholangitis), mu odontogenic maronda, yokudzivisa anogumbura urongwa mu vavhiyiwa, postoperative nguva.

Chipimo chemushonga uye nzira chikumbiro

Nokuti mushonga "Arlette" nzira kushandiswa uye dose takatsunga nomumwe uye vari novimba zera, uremu, nemamiriro itsvo kwokuomerwa chirwere. Kuti kurerutsa mukana wokuti nemigumisiro pamusoro nemudumbu, hwendefa zvinofanira kutorwa pamberi kudya, seboka, regai kutsenga uye kunwa mvura.

Varwere pamusoro makore 12 kana muviri kurema 40 makirogiramu nechiedza kuti zvive nomwero Zvirwere siyana kutora rimwe piritsi (250 MG ane chikuru chinoumba) katatu pazuva kana kaviri pazuva (500 MG amoxycillin). In mukukuvara kukuru tora dose yakaenzana 500 MG pamusoro amoxicillin katatu nezuva kana 875 MG - kaviri masikati.

Varwere 6 kusvika 12 makore, "Arlette" mirayiridzo kushandiswa anokurudzira, kwakavakirwa 1 kg kurema muviri: amoxicillin - 20-30 MG clavulanic asidhi - 5-7.5 MG. Kazhinji, dose nokuti izvi varwere yatovapo 1 piritsi (250 MG) kaviri kana katatu pazuva kana 1 piritsi (500 MG) kaviri daily. In chakakomba pacho dose anogona kaviri.

Nokuti varwere havachanyatsogoni itsvo basa iri dose uye dosing kakawanda vari kugadziridzwa zvichienderana Clearance kuti creatinine. Vaya vanotambura anuria, zvikamu pakati kudya vanofanira ngazviwedzerwe maawa 48 kana kupfuura. Varwere pamusoro hemodialysis, chitsama zvinodhaka anosarudzwa kwakavakirwa kunonyanyisa dose pakati amoxicillin.

Vanhu vakaremara vari kushanda chiropa pamwe kungwarira zvinodhaka kurapwa "Arlette". Mirayiridzo kushandiswa (chaihwoihwo), wongororo kuti nyanzvi dzokurapa akakurudzira ichi- kuongorora mamiriro muviri.

Vakwegura varwere munhu dose kugadzirisa kwakati kunodiwa.

nemishonga

Dzakananga pamazita nemishonga zvinosanganisira mushonga kuti "Arlette" mirayiridzo kushandiswa. Treatment (murwere inofambiswa zvinosimbisa) chokushandisa ichi kungakonzera zvinoverengeka zvarakasiya kubva nemudumbu muchimiro kushaya kudya, kuda kurutsa, kurutsa, manyoka. Apo neapo unogona kunzwa pamusoro kwevanhu chiropa, asi kanenge - pamusoro pokumuka cholestatic jaundice, hepatitis, pseudomembranous colitis.

Maitiro nechepakati tsinga pakushandisa "Arlette" chinodhaka aigona kuva nomusoro uye dzungu, wokusagadzikana (muchimiro reversible) uye kufenda basa.

Hematopoietic Hurongwa anogona kupindura chimiro zviratidzo leukopenia, hemolytic kupererwa neropa, agranulocytosis. It kungawedzera prothrombin nguva (mu iyi, zvichiitika reversible). Crystalluria uye interstitial nephritis - zvingangoitika zvinokonzerwa zvinodhaka kubva Urinary hurongwa.

Zvakakwana wakafara pamazita zvichibvira neutachiona kuti mushonga "Arlette". Instructions, rondedzero zvinodhaka azivise vatengi pamusoro zvaibvira kukura pruritus, urticaria, erythematous mapundu. Apo neapo unogona kunzwa pamusoro zviratidzo exudative erythema multiforme, angioedema, anaphylactic kuvhunduka. Pane ruzivo pamusoro nomumwe kuratidzwa divi anokonzerwa muchimiro Stevens-Johnson urwere, uye exfoliative dermatitis.

Contraindications pakushandisa "Arlette"

The pamazita zvikonzero kuti tizvidzore kushandiswa kwemishonga inorwisa mabhakitiriya, nokuti medicament unotora "Arlette" mirayiridzo Chinyorwa. Contraindications kukurambidza kubvuma kune varwere vari kutambura nomumwe hypersensitivity kune huru uye ebetsero zvinoriumba zvinodhaka kune vamwe Beta-lactam antibacterial vamiririri (penicillins, cephalosporins, uye zvichingodaro. N.). Regai kugadza "Arlette", uye neavo munhau ane zvinyorwa kutyorwa kushanda chiropa pakurapa amoxicillin uye clavulanic asidhi ari kunzwisisa. Mishonga contraindicated vaitambura mononucleosis uye lymphocytic neleukemia, sezvo kunowedzera mukana wokuti kusimukira exanthema.

The chikonzero pokuramba kurapwa pamwe mushonga uyu uri chisingaperi renal kukundikana uye vana anosvika 6 makore.

Kana vakadzi pamuviri, vanogona kutora "Arlette" chete kana kunobatsirei kuna mai indisputably kupfuura vakanzwisisa panjodzi kuti azvarwa. Kana lactation huru zvinoriumba zvinodhaka riri shoma mumukaka, saka unofanira kukurukura nachiremba wako mubvunzo pokungoda kuramba breastfeed.

Kunwisa mishonga

Zvirwere zviri zvomudumbu turakiti - ndiro boka guru nezviratidzo yo zvinodhaka ovhadhozi, "Arlette" (piritsi). Mirayiridzo yokushandisa, murefu uchapupu akashuma kurutsa, manyoka, marwadzo mudumbu. Uyezve, pangava ezvinhu akadai hope, uye dzungu, nokutambudzika. Kashoma chaizvo kunzwa pamusoro pfari.

Kana ovhadhozi zviratidzo ane Zvakanyanya Kunaka Panguva Yepamuviri mhinduro kuti murwere - kuva pasi pokudzora nyanzvi. Treatment nyaya dzakadaro symptomatic.

Kana chokwadi yokugamuchira unacceptably yakakwirira dose hakuna kupfuura 4 days ago, zvakakodzera kugeza kunze dumbu uye zvinodhaka, adsorbents (akadai neactivated charcoal) kuti kuderedza Absorção de Água. Nokuti kubviswa kubva pamuviri amoxicillin uye clavulanic asidhi unoshanda hemodialysis.

Kudyidzana nevamwe zvinhu uye mishonga

Yakafanana kubvuma "Arleta" uye "methotrexate" achawedzera toxicity okupedzisira. Sezvineiwo ipfupi uye achaita kuderedza Absorção de Água ari kurapwa antacids, glucosamine, aminoglycosides. Ascorbic acid, nekusiyana, kuwedzera Absorção de Água - mashoko akadaro kunosanganisira mushonga unorwisa "Arlette" mirayiridzo Chinyorwa.

Mutengo mishonga zvinosiyana zvichienderana chipimo chemushonga nekudunhu, asi ivo zvinowanikwa zvakasiyana-siyana vatengi. Naizvozvo zvakafanira kuti bvunza chiremba wako, uye hapana chokubatanidza kushandisa mishonga inorwisa mabhakitiriya nevamwe zvinodhaka.

"Arlette" napedyo zvazviri coagulants nokuda chinovhiringidza ari intestinal microflora, kuderedza kugadzirwa vhitamini K uye kuderedza prothrombin indekisi. Yakafanana womuchato zvinodhaka, anticoagulants Zvakakosha kuramba kuongorora parameters ropa pakugwamba. Kwakaderedza kubudirira nomumukanwa pamuviri.

NSAIDs, diuretics nezvimwe kugadzirira dzokurapa kudzvanyirira tubular secretion, kuwedzera ropa wevasungwa kuti amoxicillin.

Tandem "Arlette" ne "Allopurinom" anogona kukura exanthema. Bactericidal mishonga kutungamirira synergism uye zvinodhaka bacteriostatic mashandiro kuti simba - kuti daka.

mirayiridzo Special

Nokuti zvinodhaka "Arlette" (mirayiridzo kushandiswa chine ruzivo) ne zvakasiyana mishonga kubva amoxicillin zvinosanganisira Zvisinei, zvakafanana clavulanic asidhi (125 MG), tinofanira kuyeuka kuti mahwendefa maviri MG 250 amoxicillin hausi yakaenzana rimwe piritsi 500 MG yacho fuma.

Zvinofanira kurangarirwa kuti yakawanda amoxicillin kungakonzera yakanaka chenhema mhinduro pakusarudza padanho shuga iri weti kana kushandiswa ongororo maturusi, akadai Benedict kuti reagent kana mhinduro achitema. Zviri nani mune nyaya dzakadaro kuti kushandisa enzymatic siyana pamwe glucosidase.

At kushanda dziine mushonga zvakafanira kuti nguva dzose kuongorora mamiriro mashandiro ropa, chiropa uye neitsvo. "Arlette" iri yakarumbidza uwandu hakurevi kukanganisa kukwanisa kudzora nokukuitira mugwagwa mabasa zvinoda kutarisirwa uye yakakwirira kumhanya psychomotor siyana.

Price Range uye nevatengi mafungiro pamusoro mushonga

Information pamusoro zvinobvira dosages wose zvinoriumba vari zvinodhaka rine kuti "Arlette" (Hwendefa) mirayiridzo kushandiswa. Price, sezvambotaurwa, kunobva chipimo chemushonga nekudunhu umo zvinodhaka chakatengeswa. Somuenzaniso, firimu zvemapuranga mahwendefa dose pamusoro 875 MG + 125 MG muMoscow inogona kutengwa nokuda mari iri zvinobva 270 kusvika 310 rubles (zvidimbu 14 paminiti rongedza). In St. Petersburg chete pasuru achaita mari 278-282 rubles.

With Panyaya maonero varwere vanenge somushonga chigadzirwa chiri zvose zvakanaka nezvakaipa inofambiswa pamusoro zvinodhaka. A guru boka wevarwere zvinoratidzwa kwazvo chaizvoizvo mukurapa zvirwere yokumusoro kufema turakiti yokumusoro kufema neturakiti. Mishonga nokukurumidza uye zvinobudirira kutsungirira sinusitis, uye nokuregererwa kuri refu zvakakwana ipapo. Kugona kwaro pakurapa zvirwere zvinokonzerwa noutachiona vanoitwa kwechokwadi ongororo varwere.

Negative wongororo pamusoro somushonga chigadzirwa "Arlette" vanowanzobatwa nokuda kwe varwere hypersensitive kuti zvinodhaka zvinoriumba. Muzviitiko zvakadaro, vanhu kazhinji kutaura pamusoro zvarakasiya vari kushanda zvomudumbu turakiti, akadai: fufune, kuda kurutsa uye kurutsa, manyoka. About Handichamurangariri kwazvo abnormalities anenge asina ruzivo.

Zvisinei, zvinofanira kutaurwa kuti dai antibacterial pomutumwa akagadzwa nokuda nokupinda chiremba uye naivowo akanhonga Zvakanyanya Kunaka Panguva Yepamuviri dose, yakasiyana siyana divi kutsaudzira kuitika chaizvo kashoma. Kana chinhu chakadaro akaita kuitika, chiremba achasarudza zvakafanana simba uye kunyatsoshanda kuti analoginen abatsire Russian mishonga musika yakazara nemishonga ane chakarondedzera chiito.