"Dzhakavi" (ruksolitinib) mutengo dzomuzana. Where kutenga isingadhuri Dzhakavi

The mushonga "Dzhakavi" kugadzirwa ne kambani Swiss "Novartis" kwakakurumbira pakati vanachiremba vanoitira kenza.

Ruksolitinib, huru vanoshingaira wemafuta Said zvinoreva - a puroteni tyrosine kinase inhibitor. Hazvina nyanzvi pakurapa zvirwere zviri chokuita sezvo zvakanaka splenomegaly, myelofibrosis (kusanganisira nesekondari, raikura somugumisiro zvinokosha thrombocythemia uye polycythemia).

Vaongorori cherechedza kuti kushandisa zvinodhaka kwakaderedza chirwatata kukura nokuda 35%, vakawedzera upenyu anotarisirwa uye unhu. Saka toxicity yezviri chirungiso ndiyo mwero zvichienzaniswa nedzimwe zvinodhaka yakafanana chakarondedzera chiito.

Ungawana "Dzhakavi" mapiritsi kutenga isingadhuri

Asi asati achipfuura pamwe rondedzero chinodhaka, hatigoni kutaura pamusoro kurapwa kwezvirwere zvakakomba kunoda zvinodhaka dzinodhura, uye izvi hazvigoni asi kukonzera kunetseka pavarwere. Vasiye zvinokosha mishonga hazvibviri, asi kuti kwavari kazhinji zvakaoma. Saka, muna drugstores of Moscow pamusoro piritsi "mutengo Dzhakavi 'inotanga kubva 100 000 rubles.

Kuti kununurwa mumamiriro ezvinhu anogona kuuya WWW.ONKO24.COM nzvimbo apo unogona kutenga mushonga Generic inonzi. Kana zvakafanana zvakakwana, uye zvimwechetezvo pamusoro pokushandisa zvichaita mari isingadhuri zvikuru. Chokwadi kuti Generic kugadzirwa haabati mari kusimukira, yokuedzwa, uye kukwidziridzwa maturusi unobvumira vagadziri vayo kushanda pasi pamutemo rezinesi, kudzorera kusunungurwa mushonga pa mari yakaderera.

Dosing uye dose gadziriro

Varwere vanofanira kuziva kuti kushandiswa "Dzhakavi" chinodhaka ndizvo kuzvimirira zvokudya yaunodya. Uye kana panguva akamuraira nguva mvura yokunwa akakundikana piritsi, haukwanise kutora dose kaviri vavo. Hazvisi zvakakodzera nokuda kusuduruka ichi uye inotevera kugamuchira.

The kutanga dose of zvinorondedzerwa zvigadzirwa vari ushandiswe bedzi nyanzvi, zvichienderana parameters ropa - platelet count. Kazhinji, ndizvo 15 MG (p kutora 2 pazuva.), Kusanganisira dzimwe 100-200 / Nl, apo mari dzinopfuura 200 / Nl - 20 MG. Kana nhamba maplatelet ndiyo 50-100 / NL, kufadza kwokutanga dose haafaniri kupfuudza 5 MG kaviri pazuva. The kunonyanyisa dose kuchaita dzinofunga yakatora kuti zvinodhaka "Dzhakavi" mirayiridzo kushandiswa haafaniri kupfuudza 25 MG, wakatorwa kaviri daily.

Kazhinji, marapirwo yaifanira kugara ruksolitinibom count mumasero ropa (erythrocytes, leukocytes uye maplatelet) ose 2-4 mavhiki panguva kusarudzwa kubva dose uye zvichienderana nokuti sokuora zvairatidza.

Contraindications

Nokuti kushandiswa zvinodhaka "Dzhakavi" pane vamwe contraindications:

1. Pamuviri uye lactation.
2. Patient zera vaduku gumi nemasere ekuberekwa.
3. Personal ruksolitiniba kusashivirirana kana zvimwe chezvinonhuwira kugadzirira.

Sezvinotaurwa pamusoro pokushandisa aripo "Dzhakavi" mhinduro nyanzvi, zvinoreva dzinoda kushandiswa nokungwaririra pakurapa varwere renal kukundikana kana hemodialysis. In umwechete uye anosanganisira varwere thrombocytopenia, neutropenia uye kupererwa neropa.

nemishonga

In chikumbiro, sezvinoratidzwa kuda "Dzhakavi" mirayiridzo, kazhinji kuchengetwa zvinotevera nenjodzi:

• Urinary turakiti noutachiona;
• kupererwa neropa;
• neutrophils;
• thrombocytopenia;
• ropa (kusanganisira kupwanywa, mhuno uye intracranial ropa uye ropa iri nemudumbu);
• kufuta;
• dzungu;
• hypercholesterolemia;
• kurwadziwa nemusoro.