"Engerix" - nehepatitis B mushonga wacho mushonga nziyo, analogs uye wongororo

"Engerix" - mushonga kunangana kukura nehepatitis B. Somugumisiro kushandiswa kwayo unobudisa kutapata kuti causative mutumwa chirwere. The mushonga - utachiona antigen (chikuru pamusoro), wokupedzisira kuchenesa kwacho, adsorbed pamusoro aruminiyamu hydroxide. The mushonga zvinoberekwa recombinant DNA Michina Implementation.

The efficacy zvinodhaka kana chinotarisirwa kuti vakuru, vana nevacheche vari pangozi, paavhareji 98%. Kubva kwokubatsira mushonga inoumbwa HBs-dzakananga antibody, izvo anodzivirirwa nehepatitis B. coinfection "Engerix" kunogona chiropa D.

Murwiyo, kusunungurwa chimiro "Engerix" chinodhaka

Nzira iripo mune capsules. The dose chinofanira kutarisirwa mwana anoenderana 0.5 ML kuti mukuru - 1 Rine mamiririta. Kavha rine kusvika zana ndiro (gumi, kana ane zana namakumi matanhatu).

"Engerix" mugadziri unoberekawo ndiro kuti vanoumba 5 Rine mamiririta (unoenderana vana 10 mishonga) uye 10 Rine mamiririta (unoenderana 10 mishonga kuti vakuru) mushonga. The packs it muri mabhodhoro mashanu "Engerix".

The mushonga ndechokuti vakuru

The Zvinoumba 1 Rine mamiririta mushonga zvinosanganisira utachiona hwakakura antigen (20 micrograms) chiri zvaisanganisira aruminiyamu hydroxide. The akashandisa zvisaora Pfungwa ane zita "2-Phenoxyethanol", pane kungoda thimerosal, kubva pakushandisa fuma iyi vari kugadzirwa medicament. Kubvisa thimerosal kubva yokudzivirira, kana kuchenesa rinoitwa. In kugadzirwa zvinodhaka akashandiswa uye yavaibvisa digidrofosfatadigidrat gidrofosfatadigidrat, mvura chena iri vakawedzera.

A mushonga vana

To 1 ml kugadzirira "Engerix" mushonga sezvamunoita sezvinotevera:

• utachiona hwakakura antigen (10 micrograms);
• Minimum uwandu yamarudzi thimerosal;
• mamwe zvinoriumba (zvakafanana ari kugadzirira mukuru).

Pharmacological migumisiro

The antigen rinobudiswa kuburikidza mbiriso Saccharomyces tsika, ine imwe simba. Yakabudiswa Saccharomyces achibvisa masero kubva antigen, muitiro izvozvo kwazvo mukuru-azvipire kucheneswa. Pane umbowo kuratidza kukwanisa "Engerix" kuderedza mukana wokuita dzichiri carcinoma hepatocellular nokuda kwokubatsira pakati mushonga kuvana vaduku.

Zvairatidza yokushandisa

"Engerix" mirayiridzo kushandiswa yakarumbidza kuti kudzivirira nehepatitis B, izvo kukonzerwa panowanikwa utachiwana. Vaccination inokurudzirwa pa-njodzi mumapoka. Zvinosanganisira:

• vanamukoti;
• vanhu vachararama kuburikidza nhego kuisirwa;
• vagari kumatunhu endemic kuti nehepatitis B;
• vanhu vachitambura udhakwa;
• zvokurapa vadzidzi;
• Varwere vari vakagadzirira kuita mabasa kana invasive chirwere maitirwo ezvinhu;
• vatakuri utachiona hunokonzera kukura hepatitis C;
• vashandi vanozvigadzira immunobiological kugadzirira ane zvinoumba ropa;
• vana nherera, zvikoro chebhodho;
• rabhoritari vashandi, kusora mashoko evanhu;
• Varwere vari kurapwa nokushandisa fuma majekiseni;
• vanhu vachitambura nekuora hepatitis C chimiro;
• Vana vanoberekwa nevakadzi vari vatakuri causative nomumiririri nehepatitis B;
• vanhu vanozivikanwa jeko-sero kupererwa neropa ;
• avo vari neVadzidzi vanhu vakaona nehepatitis B chero chimiro;
• Vanhu ava mukuru panjodzi makaita nehepatitis B kubva vakasununguka dzepabonde;
• Vanhu vanoronga kuenda kudunhu endemic kuti nehepatitis B;
• Vanhu vanotambura nechirwere chiropa nezvirwere kuyerera;
• varwere vachida kuwedzerwa ropa, anyatsoronga zvinhu zvinobva muropa.

Vaccination pamusoro nehepatitis "Engerix" kunogona kuitwa chero zera. Wakaitwa vaya vasina nhomba kare, uye vaya vari rimwe boka panjodzi.

Contraindications

The mushonga hauna chinotarisirwa mu hypersensitivity iyo dzakaonekwa pashure yapfuura zvinodhaka jekiseni. Kuvapo zvirwere zvakakomba uye rikwanise kuitika, zvakakomba kutapuriranwa pezvakaitwa umo fivha, - contra-zvairatidza kuti kubaya.

Pasinei nokuti uchapupu kukuvara mushonga kuti mudumbu, ndisipo munguva mukubereka vana vakadzi kashoma baya. Implementation Its kunowanzoitwa chete chinokosha zviitiko apo pane zvimwe zviratidzo.

Kushandisa mushonga, kuti chipimo chemushonga

Intramuscular Kutarisirwa iri kunoitwa mune anterolateral rorudyi mugove (vana vaduku, vacheche) ari deltoid tsandanyama. Zvichida subcutaneous Kutarisirwa, asi voitakura muna zvisingawanzoitiki nguva chete kana murwere akarova ropa coagulation hurongwa. Kusonanidzwa "Engerix" kumboita nomutsinga. Nokuda yakaderera ndingangokuvara masoja mhinduro vanodzinga intradermal, subcutaneous uye intramuscular jekiseni kupinda buttock.

Vachikwanisa of mushonga pakarepo asati jekiseni zvakanaka dzakazungunuka kusvikira whitish slurry iri zvakaenzana anoparadzirwa. Kugadzirira inofanira kuva nezvimedu wokumwe. Muzviitiko apo chimiro mushonga asingadi anoenderana tsananguro iyi, nzira iyi haina kushandiswa kubaya.

Kana "Engerix" (mushonga) rinoshandiswa chinu, ari kubatwa nomumwe dose zvakakodzera kutora chena tsono uye sirinji. Started Bhodhoro anogona kushandiswa kusvika vaifanira yokuguma zuva. Izvi zvinoda zvaidiwa mureza wakasiyiwa nemitemo antisepsis, asepsis.

chipimo chemushonga

Vaccination majekiseni anodzivirira zano iri kwatemwa, iyo unogamuchirwa munyika. Dosing zvinoreva akaita maererano nezera:

• kusvika makore 19 - 0.5 Rine mamiririta;
• Makore 19 - 1 Rine mamiririta;
• pakurapa varwere vari hemodialysis Unit, - 2 Rine mamiririta.

Okudzivirira muduku majekiseni

Mwana majekiseni kuita pashure pokuberekwa, mwedzi mumwe uye mitanhatu. Kana pakutevedzera zano rakadaro nechekare mumwedzi wechinomwe upenyu hwomwana hatiwani utachiona hwakakura kubva nehepatitis B. Kana paine chikonzero mhanyisa iyi, rinotevera jekiseni rinoitwa pashure pokuberekwa rokutanga romwedzi youpenyu, uye ipapo - yechipiri. Nezuva regumi namaviri romwedzi pamusoro Implementation pakati revaccination runodiwa.

Kana munhu mukuru ari pauduku haana kugamuchira mushonga mushure dose kuti nyaya wechipiri pazuva rechinomwe, wechitatu - ari maviri kutanga. Rimwe gore pashure kushandisa zvinodhaka rokutanga chinotarisirwa kakawanda mushonga.

Kana hemodialysis nzira kuti nehepatitis B mushonga 'Engerix "akasuma pasi zano: Day razero - thirties - sixties. Ataurazve kushandisa mushonga mukati memwedzi mitanhatu pashure yokutanga yaitonga. Varwere kuti vanoumba boka iri, kuti ive jekiseni ane miviri dose (2 MG). Pashure kwokubatsira mushonga inokurudzirwa kuita serological bvunzo (kuipa zvazvingava Hachifaniri asingasviki 10 Iu / l).

Vacheche nezvinetso zvakakomba mune itsvo raitongwa 0.5 ml chigadzirwa, chero dzakakodzera vachinamatira matunhu majekiseni. Chete dose zvinodhaka chinodiwa vachangoberekwa vanoita hemodialysis.

Kana munhu yave kukanganiswa zvinhu nokuda izvo zvinogona kuitika chirwere, shandisa nokukurumidza kubaya purogiramu. The dose yokutanga pamwe mishonga, izvo une imwe immunoglobulin. nevasori kwakadaro vane kunambwa nehepatitis B. jekiseni zvinodhaka "Engerix" mirayiridzo Chinyorwa anokurudzira kuti imi muite kunze immunoglobulin majekiseni (munzvimbo dzakasiyana).

Kana uchida baya achangoberekwa ane mai - the mutakuri nayo utachiona kana chirwere vachirwara vane hepatitis B, kubvira mumwedzi wechitanhatu pamuviri, pashure kuzvarwa mushonga raitongwa kwaari yokutanga hafu yezuva. Uyezve kubaya rinoitwa nenzira expeditious nenzira. Dzimwe nguva, muna Muzviitiko zvakadaro inokurudzirwa kushandisa mushonga kuti immunoglobulin mamorekuru.

Apfuudza murume yose Zano kubaya pamusoro nehepatitis B revaccination hakusi zvakakodzera. Mushure dialysis uye murombo zvirwere mhinduro inogona kupiwa munhu booster dose. Kudiwa Implementation rinotsanangurwa serological bvunzo.

Marwadzo "Engerix"

Funga kusafarira womuviri, kukura izvo zvinogona kukonzera mushonga 'Engerix ". Mirayiridzo tsanangura kwakadaro nemishonga, umo njodzi zvetsandanyama nemapfupa uye mumatumbu enyika. Pangava hadzina kufambiswa zvakanaka zviri kushanda peripheral tsinga, zvemwoyo, zvinobvira kuchinja nechepakati tsinga. Pashure jekiseni, anogona kuonekwa nevamwe vemunzvimbo sema kuita.

Munhu anogona kuita kuti mushonga kuratidzwa yokuSpain-kufanana zviratidzo, zvakawanda zvive, nefivhiri, uye kurasikirwa nesimba. Mune zvimwe zviitiko, kuva thrombocytopenia, lymphadenopathy, rinowanika bronchoconstriction. Kazhinji, akaipa chinja kusvika mushonga uri munyoro.

Zviitiko ovhadhozi of mushonga hazvina zvaziviswa. How kuita mumamiriro ezvinhu akadaro kukura zvisingadiwi zviratidzo, kusingajekeswi mumirayiridzo.

Vasati kushandisa, ukanyatsoongorora pfupiso uye chiremba.

zvinodhaka kwavatori

"Engerix" (mushonga) vachishandisa immunoglobulins apo kudzivirira chiropa B, hazvideredzi titer pamusoro antibodies inopiwa kuti rokutarisira zvinodhaka izvi rinoitwa yoga dzakasiyana pfungwa. Zvikasadaro, kuti chinoratidza haangazorori inowanzotorwa siyana.

Unogona kushandisa mushonga kuti kunotadzisa kukura nehepatitis B, pamwe nemamwe zvishandiso izvi mhando, ayo anoratidzwa mune Karenda majekiseni anodzivirira uye kubaya kuzvidzivirira nechiyero pamusoro dambudziko zviratidzo. Zvakakosha kuti zvakasiyana yokudzivirira vaviri vari kutarisirwa akaparadzana syringes panguva dzakasiyana pfungwa mbiri.

Kusonanidzwa "Engerix" aigona kuva wokupedzisira Danho iri chikamu nehepatitis B majekiseni muzviitiko apo akatanga kushandisa mamwe yokudzivirira kuti vane zvimwechetezvo. Pasi chete ezvinhu, "Engerix" rinogona kushandiswa panguva revaccination.

Nenjodzi yacho muviri pamwe mubatanidzwa mushonga zvinodhaka zvakasiyana yakaonekwa.

Zvokungwarira

panguva pamuviri

Tichingotarisa, mukana yokukuvadzwa kuti mudumbu iri shoma nokuda pakatanga yacho mushonga. zvidzidzo Clinical, izvo aizojekesera migumisiro "Engerix" pamusoro muviri, kusanganisira panguva yepamuviri havana kwakaitwa. "Engerix B" (akafanana chete) anobatsira jekiseni vakadzi nepamuviri, chete zvakakodzera uchapupu isingachinji chiremba.

Features zvinodhaka

The incubation nguva kuti nehepatitis B kunoratidzwa yokuti ndedzoupenyu chaizvo, saka pane mukana Isimba rakadini rinogona kubudiswa noutachiona kuyerera panguva kubaya. In varwere izvi, kudzivirirwa nehepatitis B hazvibviri.

Nokuti mushonga haangagoni kudzivisa panowanikwa zvirwere, kukura iyo inobatsira vamwe utachiona. Somuenzaniso, mushonga riri basa kana zvakakodzera kudzivisa kutanga nehepatitis A, C uye E. Zvinoitawo asina aida zvainoita utachiona nedzimwe hosha umo chiropa zvinovhiringidzika.

"Engerix" (mushonga) pashure sumo mumuviri kunokonzera masoja mhinduro, mashoko ayo hunotsigirwa zvinhu zvakawanda. Somuenzaniso, masoja mhinduro ino iri pakutsvaga bonde womunhu, zera rake, kuvapo zvinokuvadza akafanana kusvuta, nzira iyo mushonga wakatangwa. Kazhinji, pashure pemakore makumi mana, kuti zvirwere mhinduro iri shoma raidudzwa kupfuura vanhu vaduku. Vanaamai vakadaro anopedza okuwedzera majekiseni sezvo zvakakodzera.

Kana murwere ane utachiona hweHIV, mamwe matambudziko zvirwere uye somugumisiro dialysis angasakwanisa kuita yakakwana antibody titer. Kana mukuru kosi Haazobvumiri hwomukova zvinozoita, maererano migumisiro kuongorora kungada yokuwedzera majekiseni. Nokuda kukwanisa kukonzera anaphylactic siyana, izvo anosiyana mushonga mhinduro 'Engerix' vakaudza kudiwa kuti anokosha zvishandiso kuti kubvisa migumisiro ichi mhando, panguva yaitonga chezvinodhaka. Allergies anogona kuonekwa nokukurumidza, saka unofanira kuva kwemaminitsi matatu kuchengeta ezvinhu omurwere iyo jekiseni chakaitwa.

In pamberi zvishoma chirwere muna nhomba muviri kunova zvinogoneka apo tembiricha muviri anodzokera dzose. The pana icho aronga kuzozivisa mushonga, inofanira kubatwa nevamiririri aiendeswa Anti-kuvhunduka mishonga.

The mushonga inogona kushandiswa kana matambudziko ari chiropa, ayo nokungwarira dzakabatwa vanhu vakwegura.

zvinodhaka analogues

In kudzivisa nehepatitis B zvinoita kuti vasarudze kuti mushonga 'Engerix "kana" Regevak ". Analogs kuti "Engerix 'The zvinotevera maturusi dzakakurumbira:" Euvaks "," Biovak ". Zvichida kubaya "Eberbiovakom HB", "Shanvakom", "HB-Vaks." Inzwi mushonga yasarudzwa chiremba.

Reviews kuti "Engerix" rinoreva

Kana zvakakodzera, itai kuti tichiita kubaya pamusoro nehepatitis B mushonga kazhinji "Engerix" rinoshanda. Vabereki havana kucherechedza chero chaiyo nemishonga, vari kazhinji kugutsikana mugumisiro. Pari zvino pane yakawanda nyaya dzinovaka pamusoro zvinodhaka.

"Euvaks" ndiyewo chaizvo nevakawanda mudziyo, asi vabereki vanofunga hazvisi kubudirira sezvinobvira "Engerix". Reviews anoratidza kuti shanduro wechipiri mushonga vanowanzobatwa ndakarumbidzwa navanachiremba.

Kugadzirira haibatanidzi nemavhairasi, hakuna tusingaoneki akaurayiwa, ndoda vapenyu. Hwaro mushonga - antigen akaumbwa yakaisvonaka mbiriso netsika.

Kuita chero mushonga kunogona kuguma zvishomanana pfupi vanotaura kuti utano, asi, hepatitis B «Engerix" kazhinji zvakanaka kudzivirirwa. Mune zvinoitika mamiriro dziviriro yezvirwere mumuviri nguva dzose aida masoja norudaviro aripo.

Havasi vanhu vose vanoda kuva nhomba, asi tinofanira kunzwisisa kuti pasina kwavari ukamhanya ngozi pazvirwere zvakawanda ngozi. Kana kubaya zvinodhaka "Engerix 'nyanzvi inorangarira vakawandisa siyana zvinoita, iyo anobvisa zvinoita kukuvadza utano. Kazhinji kacho, Vongai nenguva kushandiswa mushonga regai kuva chirwere.

Stay utano!