Hemolytic-uremic chirwere - chii?

Hemolytic uremic chirwere chiri chiratidzo, iyo kunoratidzwa muchimiro hemolytic kupererwa, OPN uye thrombocytopenia. Kokutanga chirwere ichi anorondedzerwa muna 1955. Maererano nenyanzvi, vanenge 70% nyaya nechirwere muvana mugore upenyu rokutanga, uye chete zviitiko shoma hwakanyorwa nedzevakuru. Munyaya ino tichataura pamusoro chirwere ichi, uyewo tarira sei kubatwa ne nzira ano hemolytic uremic syndrome.

pakarepo zvikonzero

Kukura ichi chirwere nyanzvi pane aripo zuva chokuita zvinoverengeka. Zvikurukuru izvi zvinokonzerwa nemavhairasi zvakananga hunokachidza kukuvara rirambe richibvira endothelium atumidzwa glomeruli. Ukuwo chikonzero angarara muna DIC uye zvokuimba kukuvara erythrocytes. Zvinofungidzirwa kuti ekupedzisira inogona zvakakuvadza panguva ndima kuburikidza capillaries kuti glomeruli pachavo, izvo zviri zvinozoita akazadzwa fibrin clots.

chikuru zviratidzo

Hemolytic-uremic chirwere kunoitika runonyanya muvana vane nokukurumidza kuderera weti goho, asi pasina zviratidzo pachena zvokusava nemvura uye pakanyorwa pfupi zvakajairika VEO parameters. Kana mwana aine fivha kana kurutsa akazviratidza kazhinji chirwere mberi nokukurumidza - paiva chepfungwa edema. Kazhinji, hemolytic uremic chirwere iri nechimwe mwana akacheneruka-ganda, muna zvisingawanzoitiki zviitiko, pamwe kwemakomo diki.

diagnosing

Kuti asimbise chirwere chakadai hemolytic-uremic chirwere, iwe unofanira kupfuura dzakatevedzana nemiedzo, kusanganisira wakakwana ropa kuongorora. Chete pashure zvakazara kuzviongorora murwere anogona kutaura zvimwe kurapwa.

Modern nzira kurapwa

More ichangopfuura kupiwa chirwere kufa kwakanga yakakwirira kwazvo (80 100%). Zvisinei, masayendisiti ari kuramba kutsvaka dambudziko iri. Saka akasikwa mano anonzi "chakagadzirwa itsvo", kuonga zvinhu zvachinja uko zvikuru. Nhasi, nzufu anenge usambofa kuitika (pakati vaviri uye gumi muzana). Vangave chete panguva mukupera chirwere kuonekwa, uyewo kugadzirwa kwepurogiramu kusingarapiki pezvakaitwa muuropi nokuda kwayo kuzvimba. Zvinofanira kucherechedzwa kuti vakadaro chirwere chiri atypical hemolytic uremic chirwere, kazhinji zvinoda kubva 2 kusvika 9 muzvirongwa (daily) kushandisa "kubata itsvo". By dialysis ichi vanachiremba vanogona kuramba kuipa kwevari metabolites, uyewo kudzivirira pfungwa kuzvimba.

mataridzikiro

nzira Modern kubvumira vana kutsungirira dambudziko iri. Zvisinei, izvi zvinoita chete chiitiko kuti chirwere akanga dzakaonekwa mu vepakutanga huchiri. Zvikasadaro, mukana wokuti uzonyatsotanga zvishoma yakaderera. Maererano nenyanzvi, mamiriro ezvinhu pasina zvakanaka mhinduro pamusoro chikamu muviri mushure 2-3 purogiramu hemodialysis, uprofita zvisingafadzi. chaizvo.