"Indomethacin" (Mahwendefa): mirayiridzo kushandiswa, zvechokwadi

Mumwe vamiririri boka nonsteroidal Anti-anogumbura zvinodhaka ari chinodhaka "Indomethacin" (Mahwendefa). Nokuda kwayo Anti-anogumbura, unonyaradza marwadzo uye antipyretic migumisiro kushandiswa kwayo nokuda pakurapa anogumbura zvirwere, marwadzo, kuderedza kuzvimba uye rokudzorera kwemajoini mufambo.

Description rekugadzirira

The chikuru vanoshingaira wemafuta zvinodhaka ndiko indomethacin, izvo chokuita indole acetic asidhi nomukaka. Inside kavha medicament "Indomethacin" anorondedzera sezvo mahwendefa muperekedzi zvinhu pamwe rwokudzivirira enteric unhani runovabvumira zvinoshingaira mumiririri kuti kusunungurwa ura, pavaigona kutora chikepe chaienda mudumbu. Pezvakaita kumativi mapiritsi, biconvex, musoro wakafukidzwa nechiedza mashava nevamwe.

Mahwendefa vari akawanda dosages: 25 MG, 50 MG uye 100 MG kuti indomethacin. Available muna 10 kana 40 zvidimbu por rongedza.

All chipimo chemushonga siyana

Uyezve pamahwendefa, pane mamwe marudzi "Indomethacin" kugadzirira nemumuromo kushandiswa Somuenzaniso imwe kuramba kusunungurwa Kamudzira chipimo chemushonga pamusoro 75 MG. For rectal Kutarisirwa, suppositories inoshandiswa aine dose 50 MG. Nokuti kunze mafomu akasika mafuta 5% uye 10% uye 3% gel.

mashandiro chiito

The medicament chinhu nonsteroidal antiinflammatory mumiririri systemic chiito, ine antiinflammatory, decongestant, unonyaradza marwadzo uye antipyretic nemigumisiro. Vasiyana mushonga "Indomethacin" (Mahwendefa) gwaro mashandiro unotora rondedzero huchishanda zvinoshingaira chirungiso chokuita vasanyanye cyclooxygenase basa mhando 1 ne2. Uyewo, enzayemu ichi ane usingashandi kwakabatsira arachidonic asidhi izvo kunoderedza ayo kutendeuka kuti prostaglandin. Izvi zvinhu zvinokonzera kuzvimba uye marwadzo.

Indomethacin Exhibits antiplatelet zvazviri, kuderedza platelet clumping masero eropa. Fuma attenuates marwadzo panguva kurwadza kwemajoini wakadzikama uye pafoni mamiriro, kunoderedza, anowedzera kuwanda inofamba mangwanani kuomarara uye kuzvimba. Action indomethacin zvainanga mukuderedza chokutsva. The kunonyanyisa zvazviri hunopiwa rechinomwe zuva kurapwa, mahwendefa zvinodhaka.

kuti anobata

Inobva mashandiro chiito, "Indomethacin" Hwendefa kudzidziswa Chinyorwa anokurudzira kushandisa kuti systemic nokurapa:

• articular urwere;
• anogumbura zvirwere zvetsandanyama nemapfupa ezvinhu anokonzerwa RA, psoriatic, RA, yokupara chearthritis, nechando mafudzi, ankylosing spondylitis, vadyi chirwere muna deforming osteitis uye uretrookulosinovialnom chirwere;
• chinopedza zvirwere zvetsandanyama nemapfupa ezvinhu anokonzerwa osteochondrosis pamwe radicular chirwere, osteoarthrosis pakati mapfundo, kunze pamagaro uye intervertebral arthrosis;
• diffuse chirwere, kufukidza connective tishu;
• rheumatism;
• suppurative anogumbura maronda ose periarticular mabhegi nemarunda;
• kurwadziwa zviratidzo panzvimbo dzapasi shure uye nezvimwe zvikamu musana kana sciatic neuralgia nedzimwe tsinga, kuzvimba tsandanyama;
• dzechimwe kuzvimba iri nyoro nyama kana majoini.

Inogona kukubatsira kutsungirira nomusoro, kumwedzi, ndichinzwa zino, tiibhii.

Webetsero mumiririri kuti yezvirwere uye anogumbura zvirwere zvakadai pharyngitis, tonsillitis, otitis anoshandisa medicament "Indomethacin" (Mahwendefa). Zvairatidza zvinosanganisira kurapa cystitis, adnexitis, prostatitis.

The mushonga unoshanda kuti kubviswa febrile chirwere kwakabatana chirwere Hodgkin raMwari, rwekenza yelymphoma, metastatic namamota, kana asina kuita paracetamol uye acetyl salicylic acid.

How kutora

"Indomethacin" mushonga pamahwandefa chinotarisirwa kuti murwere neimwe chipimo chemushonga kwakavakirwa mwero chirwere. Kazhinji, vanhu vakuru anotanga kugamuchira dose 25 MG katatu pazuva pashure kudya.

Kana mugumisiro kurapa iri kushomeka raidudzwa kaviri chipimo chemushonga kusvika 50 MG ka3 pazuva. Maximum zvinobvumidzwa dose haafaniri kupfuudza 200 MG indomethacin. Pashure kuvandudzika chinokosha kunokonzerwa zvinodhaka mushonga, kurapwa inofanira kumiswa chete pashure 4 mumasvondo uchishandisa rapfuura nguva kana kuderedzwa dose. Kana varwere tora mapiritsi kwenguva refu "Indomethacin" mirayiridzo Chinyorwa anokurudzira munhu dose pamusoro 75 MG ose vanoshingaira wemafuta pazuva.

mabatiro vana

Nokuti mwana zuva dose dzaona nokuda vachiwedzera 2.5 kana 3 MG pamuviri wake guru, rakundwa kuti 3-4 nguva. Nokuti mumwe zera boka akapa kushandisa kwokutanga zuva dose:

• vana 3 makore 7 raitongwa kubvira 50 MG 75 MG, izvo unoenderana 2 kana 3 mahwendefa;
• vana 7 kusvika makore 12: kubvira 75 MG kusvika 100 MG, izvo rinoenderana 3 kana 4 mahwendefa;
• Vana makore 12 ushandiswe kubvira 100 MG kusvika 125 MG, izvo unoenderana 4 kana 5 Mahwendefa.

Mumazuva mashoma okutanga, unofanira kutsvaka kuti mushonga uri muviri wemwana, saka shandisa chiduku dose kurapwa. Ya yokurapa ne "Indomethacin" (Mahwendefa) kuraira rinoratidza sezvo nguva kubva 6 7 days.

Features mutambo

Panyaya iyi, pane mukana nemigumisiro pamusoro kugamuchirwa rinoreva "Indomethacin" pamahwandefa, zviri nani kuti varege kushandisa mishonga chakasimba rheumatic nefivhiri muuduku. Aibuda kupinda mukaka, zvinoshingaira chirungiso opinda ropa mwana, inowedzera vasiri jaundice ari mucheche uye kukundwa chiropa masero. Kuti izvi zvisaitike, kudzima achiyamwa.

Vakwegura, varwere hosha chiropa, itsvo, zvomudumbu turakiti, dyspeptic zviratidzo, BP, congestive mwoyo kukundikana pashure pokuvhiyiwa, chirwere chinonzi Parkinson, pfari, nepamuviri muna I uye II trimester apo mabasa kurapwa Indomethacin kunodiwa kuongorora mamiriro nhengo. Zvakakodzera kudzora mashandiro matambudziko nhengo, kamwe ose 7 days kuongorora peripheral ropa.

Kana kare ndivo sema vasiri steroidal Anti-anogumbura zvinodhaka, mushonga "Indomethacin" (Mahwendefa) anogadzwa muzviitiko.

Hatidi kuvakurudzira kuita basa ngozi vari kurapwa, sezvo huchaita kutarisirwa uye psychomotor basa.

Kana iwe usingagoni kutora

Pane zvirwere umo mishonga contraindicated "Indomethacin" (Mahwendefa). Kushandiswa Its hazvibviri:

• hypersensitivity kuti indomethacin;
• pamberi erosive uye maronda maronda ari zvomudumbu wemuTesitamende rikwanise chokutambudzika;
• apo "asipurini vanamwari vatatu vatatu", vaine kusashivirira kuti acetylsalicylic acid, nasal polyps uye Árbol asima;
• panguva hemodyscrasia;
• kana raidudzwa yekupindurwa chiropa uye itsvo;
• panguva kunonoka kuti munyu uye mvura nezvinhu zvichiita peripheral edema;
• kwazvo chisingaperi kukundikana hunhu myocardium;
• panguva yakakwirira kumanikidzwa;
• Árbol asima;
• ari kuzvimba rwatata;
• muna III trimester pakati gestation mwana;
• achiyamwa;
• Vana vaduku pane 3 years.

nenjodzi

Mishonga "Indomethacin" (Mahwendefa) anogona chokuita yaivhuvhuta zviitiko isakarurama kukanganisa ezvinhu muviri womunhu. Nokuti zvakafanana nenjodzi zvinosanganisira kuda kurutsa, kudya marwadzo mudumbu, bloating, kupatira, fufune.

Mune zvisingawanzoitiki Muzviitiko, nemishonga inogona kuitika erosive uye maronda maronda, kubuda ropa uye perforation mudumbu uye intestinal masvingo; applasticheskoy kana hemolytic kupererwa, leukopenia, thrombocytopenia, agranulocytosis, mapundu, bvudzi kurasikirwa, ganda kuvaviwa, nezvipusha, angioedema, bronchospasm.

Zviratidzo chepfu epidermal necrolysis, chaizvo kashoma akacherechedza anaphylactic kuvhunduka, erythema nodosum.

Panguva kurapwa kunogona kukanganisa kushanda excretory renal uye chiropa, izvo anowedzera uwandu bilirubin, hepatic transaminases.

kushandiswa kwezvinodhaka "Indomethacin" (Mahwendefa) refu hazvirevi siya nenjodzi chokuita hope vachivavhiringidza, dzungu, peripheral neuropathy, nomusoro, nokusagadzikana, kushatirwa, kurukutika. Vari ne dzisavhiringidza pamusoro cornea, conjunctivitis, kunzwa vanotaura, tinnitus, BP, edema.

Reviews

Zvakakosha kutevera zvose mitemo chinodhaka, siya contraindications zvose.

Vari hwakakanyiwa pamusoro kubvuma "Indomethacin" chinodhaka wongororo. Mahwendefa vane zvakawanda nemishonga pane chipimo chemushonga siyana dzokushandisa kwokunze. Uyezve, kushingaira zvinodhaka chokuita FIs pakati cyclo-oxygenase 1 ne2, izvo vaiona kuti zvishoma runziro uye kukonzera vanoverengeka zvisingadiwi zvinoitwa gastro-intestinal turakiti.

Rheumatologists vavo varwere, vanachiremba vanovhiya kazhinji kushandisa mishonga vatsva kubva boka oxicams. Ivo tunodzivisa cyclooxygenase mhando 2 chete, pasina kukanganisa enzayemu mhando 1, iyo dzinovimbisa kugadzirwa prostaglandins kuti kudzivirira zvomudumbu hurongwa. Ndokusaka oxicams kuita zvishoma kukuvadza dumbu pane mushonga "Indomethacin" (Mahwendefa). Instructions kunaka inofambiswa rinosanganisira tsanangudzo nemishonga, asi izvi hazvirevi kuti mushonga vanofanira kuratidzwa. Zvose zvinoenderana zvinoitwa nhengo.

Varwere vakawanda, izvi zvinoreva kuchengetedza kubva musana marwadzo, myalgia, intercostal neuralgia, kana mimwe mishonga regai kubatsira. A Migumisiro chinenge regai simukai kubva pakurapa "Indomethacin" chinodhaka. Reviews zvemahwendefa akatorazve varwere yakabereka zvakanaka. Kunyange zvazvo njodzi ndiyo nguva dzose aripo, uye chete chiremba anogona mishonga negashiro yakadaro chakakomba zvinodhaka.

analogs

Hwendefa vane basa fuma Indomethacin anobudiswa neZvapupu vatorwa uye mudzimba nemakambani mazhinji, akadai kambani "Sopharma", "Ludwig Mekle" "Nycomed", "Farmahim", "Berlin Chemie Menarini," "Altfarm". Chete mushonga neimwe zita rayo zvokutengeserana, ayo akafanana webetsero zvinoriumba. All anonyatsotarira zvakafanana zvairatidza kuti kushandiswa, marwadzo, contraindications.

The inonyanya kufarirwa zvinodhaka "Indomethacin Sofarma" (Mahwendefa). Yakabudiswa ari dose 50 uye 100 MG ne "Sofarma" (Bulgaria). Rinoreva asiri steroidal Anti-anogumbura zvinodhaka.

Chimwe peya haidereri kupfuura anozivikanwa analogues - mishonga "Indomethacin 50 MG kweBerlin-Chemie" uye "Indomethacin 100 MG kweBerlin-Chemie". Achibudiswa dosages maviri (50 uye 100 MG) ne Italian kambani "Berlin-Chemie Menarini".

Mukugadzirira "Indomethacin" (Mahwendefa) vane analogues Russian kugadzirwa. Ivo zvinowanikwa zvakasiyana chipimo chemushonga siyana. ndivo vanonyanya dzomuzana:

• "Indomethacin-Acre" Chemical-Pharmaceutical Plant JSC "Akrikhin";
• "Indomethacin-Altfarm", LLC "Altfarm";
• "Indomethacin-Biosynthesis", JSC "Biosynthesis";
• "Vero Indomethacin", OJSC "Veropharm".