Mbiriso-kufanana notumwe of genus Candida

Saka nyika kuti mumwe nomumwe wedu ari wakapoteredzwa zviuru chezvisikwa roga. tiri akashama ziso harigoni kuona navo, asi kupinda kuonana navo miniti ose. Vamwe "chisingaoneki" kutibatsira, vamwe vari kuurayiwa, uye vamwe vanogona kuuya, uye kukuvadza uye nokubatsirwa. Mbiriso-kufanana notumwe ari genus Candida inongova tupukanana vakadaro kuti hazvikutadzisi tirarame tichifara nokusingaperi, asi pane zvimwe zvinhu kutanga kufamba rinopikisa, zvichikonzera candidiasis chirwere kana thrush. Nokuti zvinenge izvi hazvisi chisingakuvadzi nguva dzose, dzinonzi mikana. Total akaziva 186 mhando notumwe ari genus Candida, asi njodzi mbiri chete dhazeni marudzi. Pavari ichakurukurwa munyaya ino.

The genus Candida notumwe: unhu

Candida mbiriso kungova genus. Vazhinji zvipenyu zviri zvachose isingakuvadzi uye vanogara chitunha they chakuvhe mune yogati, dzimwe dheri zvigadzirwa, uyewo mune nemudumbu womunhu, achiratidza chikamu hwakanaka intestinal kasvisto. Notumwe zviri genus Candida vari Kurovedza, kureva, kushingaira upenyu pamberi okisijeni. Vanogona kurarama nenzira mbiri - mbiriso uye micellar. In mbiriso notumwe vari dzeraundi kana denderedzwa yotunga blastospores achiwedzera. The micellar chimiro masero fungal elongate, akatendeuka kupinda pseudomycelia. Kusiyana wechokwadi, hamuna partitions, asi pane constriction. Ivo dziri blastospores, uye chinouraya expansions hlamidiospory kaviri-vakapfeka. The micellar chimiro notumwe vanokwanisa zvisangane.

Zvimwe zvisikwa dimorphic notumwe pamusoro genus Candida zvakasiyana pakuti vanogona kuva nomuviri tenzi wake mbiri nezvimiro zvayo asi kwete kuchinja kwavari zvichienderana ambient tembiricha.

An chinokosha pfuma Candida - vanokwanisa ichivira maltose uye shuga.

Candidiasis chirwere, maererano zvichangobva kudzidzwa, mhosva anenge 20 mhando notumwe, uye ndivo C.Albicans zvikuru ngozi (60%) uye C.Tropicalis (20%). The yasara 18 zvipenyu zviri rinoparadzirwa uye zvishoma chinokosha kukanganisa kuitika candidiasis havana.

PFUPI KUTSANANGURWA pathogenic mhando

The anowanzodanwa vakasangana notumwe ari genus Candida, akadana C.Albicans. vatakuri avo anenge 8 kubva 10. Vakawanda notumwe izvi kupinda mumuviri mwana pakuzvarwa uye kurarama musingakanganise, muna nemumuromo mhango, yegurokuro uye ura. In vakadzi, vari zvakare nhengo kusangana nekutsi kwemukadzi microflora. Zvinokosha Candida mhando iyi kunowanzokonzera panowanikwa candidiasis.

Chechipiri mhando inonzi C.Tropicalis ngozi. notumwe ava kukwanisa kupinda muropa uye kurishandisa vazadze peripheral zvomukati. Zvidzidzo Recent kwakaratidza rutivi Candida C.Tropicalis basa tandem pamwe Serratia marcescens uye Escherichia coli coli, uye mhaka Crohn chirwere.

Kwete zvakajairika chaizvo, asi zviri kuonekwa notumwe ari genus Candida mbiriso marudzi C.Krusei zvikuru ngozi. Ndivo nemishonga mushonga "Fluconazole", kushandiswa pakurapa fungal zvirwere, saka zvakakosha kusiyanisa mhando pathogenic chakuvhe kutambudza murwere.

Notumwe Candida mhando C.Glabrata vaiona non-pathogenic. Ivo zviripo chete ari mbiriso chimiro uye tinobereka chete yotunga. Kazhinji, Candida Glabrata padzakacherechedza pamusoro Urinary catheters, apo anoumba nhete biofilm. chakuvhe ichi kunokonzera urogenital candidiasis.

Candida mhando C.Parapsilosis kazhinji anova chinokonzera sepsis. It anokwanisa yekutapurira ronda, kunyanya kana dzimwe zvinhu kupinda kwavari.

Mhando notumwe uye C.Rugosa C.Lusitaniae navamwe genus Candida vari apo neapo. Somuenzaniso, C.Lusitaniae munguva kubvira 1979 kusvika 1990 rakanga dzakaonekwa chete varwere 30.

Nzira chirwere

Conditionally - pathogenic mbiriso notumwe zviri genus Candida mukufamba shanduka vakava zvigadziriswe kuti avabatsire kurarama parasitic kuvapo. Vanokwanisa kumira-refu nechando uye kuomesa. Pinda womunhu, vanogona kuva chikafu tsvina uye havaratidzi kupatsanurwa namaoko tsvina uye nezvimwe zvinhu, zvakadai howa C.Parapsilosis kombera mavanga pamwe infiltration vokune dzimwe nyika zvinhu, kusanganisira uye kwete sterilized wezvokurapa zviridzwa uye howa C.Glabrata pamwe Urinary kana intravenous catheters. Most kazhinji kuva utachiona hunokuvadza marudzi C.Albicans, uye kwemaminitsi upenyu mwana wokutanga. Izvi zvinoitika pakusununguka, kana madzimai nyinyo iri pakazara pamwe utachiona izvi. Panewo zvokufungidzira kuti C.Albicans anopinda muviri mwana achiri mu embryo danho, nokuti howa vakaramba awanikwa Líquido amniótico. Kana mukadzi ari kusununguka ndiko chikamu chiduku chikamu vanhu vasiri vatakuri howa, mwana wake mumakore okutanga oupenyu anogona kuwana navo kuburikidza munyatso, matoyi uye zvichingodaro. Kutya nekuti ichi hachisi zvakakodzera, nekuti Candida, kamwe mumuviri wehondo wayo, haruzvibati chinyararire, kutomubatsira, nokudzora kukura vamwe utachiona.

Kana notumwe Candida utachiona anova chirwere

Munhu anogona kuva mutakuri utachiona upenyu apo kuramba zvachose utano. Notumwe of genus Candida kuva pathogenic chete kana kuwanda kwavo kwava kudzora. zvikonzero:

- pamuviri;

- siyana noutachiona;

- exacerbation echirwere zvirwere;

- hypothyroidism kana vhitamini kushaikwa;

--yakareba mishonga;

- corticosteroids;

- hormone zvirwere.

Chikonzero chikuru chinokonzera candidiasis, kamari kutapata. Izvi ezvinhu anogona kuitika mumamiriro ezvinhu akawanda, kusanganisira varombo zvokudya, murombo mararamiro, kakawanda mupfungwa.

Mukuwedzera, nokukundwa kukura notumwe Candida kunoitika apo zvirwere anotevera concomitant:

- AIDS (kana utachiona hweHIV);

- cheshuga;

- tiibhii;

- gastrointestinal chirwere;

- zvirwere genitourinary hurongwa;

- hypothyroidism;

- Zvimwe zvirwere ropa;

- vaginosis.

pathogenicity zvinhu

Kukura chakuvhe genus Candida vari microns 2-5 chete, saka vanogona kunzi chete nemaikorosikopu. Vaya chena kana yellowish-greyish plenochki kuti kukura iri Hagari kana Dombo iri kuonekwa pamusoro munzvimbo sei muviri - ndizvo mapoka notumwe, rinosvika mazana ezviuru nomumwe tusingaoneki. Kamwe pahondo muviri, nomufambiro notumwe zviri genus Candida? Microbiologists ongororo yakaratidza kuti mumwe howa anoedza kuva adhesion, kureva, pedyo zvisangane, mumwe angati, kukura kupinda epithelial masero dzevanhu. It tupukanana utarisire nyore rezasi ari kutapata avo vakatambudzwa, uye dzakanga wake kwemakemikari anobudiswa zvirwere. Inonyanya kushingaira chikamu batira howa C.Albicans. Kamwe pazuva mucous membranes, izvozvo inoomerera muna 100% nyaya. Most pusa howa C.Krusei. Iye arege wakaiswa, ipapo hapana chirwere. Batsirai notumwe pinda pose mapuroteni uye pamusoro mapuroteni, vamwe mamorekuru, semuenzaniso, polysaccharides uye glycoproteins, uye mamorekuru pamuromo mate. Kazhinji, Candida vari glikogenofilami (glycogen kufanana), saka kazhinji colonizes ari zvinyama apo rine zvakawanda, semuenzaniso, kuti kusangana nekutsi kwemukadzi mucosa uye kunanzvana mhango. In zvinoitirwawo mbiriso notumwe yacho genus Candida ari zodzera wakatorwa kubva nhengo idzi yakaratidza refu mukana kuti inogonesa kukanganisa-isina kuongororwa.

Panguva kutanga kwekupwanyiwa adhesion notumwe vari mbiriso chimiro, asi nokukurumidza rearranged, zvichiumba filaments refu (hyphae), izvo nyore kupinda muimba dzaparadzwa nehondo masero uye phagocytosis pamusoro leukocytes asingatani zvishoma.

Simbisa uye tenzi, tupukanana panguva upenyu hwavo pahondo muviri oga chepfu siyana:

- kandidotoksin (mapuroteni mabasa ari basophils uye rechikepe masero uye kukonzera ekunyebera response);

- 6 Mhando yakaderera samolecular uremu muchetura (yakawedzera vascular permeability, nechepazasi BP);

- lipid muchetura (leukocyte chikonzero vemo siyana uye kutungamirira chimiro granulation tishu).

Candidiasis muvana

Sezvataurwa pamusoro apa, vacheche utachiwana Candida kana mudumbu kana pakuzvarwa panguva ndima nokuberekwa Canal. Mune ramangwana, iyo chakuvhe anogona kuwana mwana mumuromo ane havaratidzi kurapwa pacifier, rinorira, pamwe teats neutachiona mai. Zviratidzo kuti mwana akanga ndabatwa thrush, zvinotevera:

- chena, koteji chizi-kufanana unhani parurimi, pamusoro yomukati pamusoro desenok uye matama;

- moodiness;

- Kuramba zvokudya.

Pasina kurapwa, kuti chakuvhe anoramba kugadzirisa uye nokukurumidza ikaonekwa miromo mwana.

Notumwe of genus Candida ari dumbu dysbiosis pachena zviratidzo zvakadai:

- manyoka;

- lethargy;

- tembiricha;

- kurasikirwa uremu.

Manyoka mu vacheche pane ngozi nokuti kuupenyu nokukurumidza kupera muviri, saka mwana anorwara kuti muchipatara. Chete muchipatara inogona naye anodiwa kurapwa (donhwe) kudzivirira mvura mvura kufirwa.

Kuwedzera kune nemudumbu uye kunanzvana mhango, thrush mune vana kuonekwe paganda. Muchiitiko chino, pane asina chena, uye mavara matsvuku akaita mutambo nekumhanyirira. Mwana anova capricious chaizvo sezvo chero akagunzva erosions atange kutambura. Kakawanda, cutaneous candidiasis mu vacheche rinowanikwa mipendero iri makumbo, magaro uye muhudyu. Pashure ivo mutambo mapundu, uri manapukeni yakarebesa, murombo utsanana uye kukodzera (chakaita zvokugadzirwa, zvakare zvakasimba) mbatya.

Mabatirwo infantile candidiasis

Kana notumwe pamusoro genus Candida pathogenic kwacho kwakatanga muna mumuromo mwana, kurapwa inowanzopiwa kuitwa munharaunda. It kunoratidzwa kubudiswa panzvimbo pane firimu chena, gadziriro chaidzo. Kare, vanachiremba raibva kuna kuzora muromo mwana pamwe girini pendi. mushonga uyu zvakanaka chaizvo, asi yakaoma mucous. Zvino kushandisa "Akriderm", "Fukortsin" mhinduro kubva borax ari glycerine.

Sezvo Kudzivirira kunodikanwa mwedzi upenyu chokutanga grudnichka kubika minyatso nehombodo, kugeza rinorira. Amai vanofanira kubata pamberi kudyisa minyatso zvinodhaka antifungal.

Kana zviratidzo dysbiosis vanopfuura mutsvina yadzo grudnichka pamusoro bakposev. Zvinonzi vaidavira kuti notumwe zviri genus Candida mu pachituru muvana vari pasi pemakore kwemwedzi 12 chinogona kuvapo akawanda isingadariki 103KOE / g, uye vanopfuura 12 mwedzi uwandu 104KOE / g. Kana mutengo wacho kupfuura, kushandisa mishonga kuti kudzorera nemiti uye kusimbisa zvirwere.

Kana candidiasis ganda sei nzvimbo antifungal kwamafuta zvakazorwa - nystatin, levorinovoy. Very kubatsira kundoshamba mwana mumvura pamwe kuwedzera muto pakutevedzana, calendula, chamomil. linens All uye manapukeni vanofanira simbi, uye kushandura manapukeni kazhinji zvakakwana, kwete akavamirira kupedza zvekupfakira.

Kana kurapwa izvi regai kubatsira, mwana wako vanopedza wokuwedzera kuongororwa uye taurira antifungal kurapa.

Candidiasis vakadzi nevarume

In vakuru, Candida notumwe anogona, savana, kukanganisa muromo, ganda uye ura. Candidiasis kunoratidzwa muna muromo caseous kubatwa, rurimi zvinofadza, matadza, mukanwa, pamatama, uye kurutivi yomukati achiperekedzwa anorwadza nezvekufadza. Dzimwe nguva ulcerate mucous. Candidiasis ganda inozivikanwa tsvuku makwapa munzvimbo okuzivisa ari chakuvhe (muhapwa, pasi mazamu vakadzi, ari muhudyu, dzinenge pasi pamabvi). mavara aya pakafunuka uye svuura, apo scratching ulcerate. Asi zvikuru vakuru vose vanotambura Candida Urinary nhengo. Vakadzi notumwe vachivata nepanhengo uye vulva, saka hosha inonzi vulvovaginitis. Zviratidzo ayo kwokutanga matanho sezvinotevera:

- chena (somukaka yakashapa) kusangana nekutsi kwemukadzi buditsa;

- kuvaviwa, kwete richipfuura, asi nekusiyana, pashure rokuchenesa kukura uye mangwanani;

- kusingafadzi kwakanaka andapeni;

- Pain panguva zvepabonde.

Kurondedzerwa kupfuura chiratidzo - notumwe of genus Candida ari zodzera wakatorwa kubva nyinyo.

Pasina kurapwa, zviratidzo zviri kuipa. Nokurwadziwa kwete chete panguva kurara, asiwo mumwe nomumwe weti, kusangana nekutsi kwemukadzi mucosa unozvimba, ulcerate, kubuda kunova mukobvu.

Varume, utachiona anonzi Candida balanoposthitis. zviratidzo:

- hurumende ichiisa cheesy mhando pabonde nhengo;

- kuvaviwa, marwadzo kana vanhurume;

- chinorwadza kurara.

Kuwedzera genitourinary hurongwa, Candida notumwe vari tupukanana pamusoro dzokunze mitumbi vanhu. Chipikiri chirwere inonzi "neonika" uye prinogtevogo chinotenderera - "paronychia". The zvinokonzera zvirwere izvi zvinogona kuva hangnail, chokupika manicure utachiona zviridzwa.

Analysis pamusoro notumwe ari genus Candida

Candidiasis wakagarira kwakavakirwa migumisiro zvidzidzo izvi:

- mumwe zodzera kubva nomumukanwa mhango kana nyinyo;

- yokudyara;

- Elisa;

- PCR.

Mukuwedzera, chiremba anogona kurayira miedzo weti uye ropa.

Kana uchironga kutora swab kubva nepanhengo uye / kana urethra, iwe havabvumirwi kugeza nayo, asi unogona chete urinate nokuda 2 maawa asati atora zodzera, kwete pava paya. Kana uchironga kutora swab kubva pamuromo, izvozvo hakubvumidzwi kuchenesa mazino.

Yokudyara kushandisa mutsvina yadzo, sputum, weti, scrapings kubva munzvimbo sei ganda uye mucous membranes. Pashure pemazuva matatu, tiwane mhinduro, hungu kana kwete mumashoko ose notumwe zviri genus Candida. Norm - ndiko kunaka. Kana miedzo kuzosimbisa pamberi chakuvhe, kuona kwayo mhando uye aikanganiswa mishonga.

Elisa ongororo anonzi enzayemu immunoassay. Zvinobatsira kuziva antibodies kuti chakuvhe uye njanji emuchina acho. Material tsvakurudzo nokuti EIA ndiro ropa kubva tsinga. Kazhinji, zvakanamirwa inoitwa pamwe bakposeve.

Zvinonzi vaiona yakarurama kupfuura PCR kuongorora zvazvinoreva polymer-chain maitiro DNA molecules yacho chakuvhe. It anoona kuvapo nayo utachiona kunyange panguva kutanga pavaipfuura chirwere. Mashoko nokuti PCR vari sputum excretion, ropa.

mabatiro

Kana murwere akawanikwa notumwe pamusoro genus Candida, kurapwa ndiyo mishonga. Inside taurira:

- "Fluconazole".

- "Nizoral".

- "Diflucan".

Externally akashandisa mafuta:

- "clotrimazole".

- "Sertokanazol".

- "Miconazole".

- makenduru pamwe pumafitsinom uye nedzimwe nzira tunodzivisa kukura chakuvhe. Vanogona kupiwa uye antiinflammatory mafuta.

Treatment kwevakadzi pamuviri rinoitwa chete zvaitika nzira. Chete Kashoma basa "Pumafitsin" nomuromo.

Kana candidiasis urogenital turakiti ndiko kurapwa zvose pabonde.

Kuwedzera kune antifungal mishonga ndivo ndishandise mavhitaminzi uye nedzimwe nzira, kutsigira zvirwere.