Mishonga "L-thyroxine." Kuongorora kwevanyori. Mirayiridzo

Mushonga we "L-thyroxine" mukugadzirwa kwawo une levothyroxine, yakafanana mukugadzirisa utachiona hune humoni husingaperi. Chinhu chacho, mushure mokunge chinyorwa, chinoshandiswa pakugadziriswa ku lyotyronine. Uye iye, zvakare, achipinda mukati memasero, anorongedza kubudirira kwavo, ane simba kune metabolism. Mushonga we "L-thyroxine" unokwanisa kuita mu mitochondria pane metabolism inokonzera, kusarudza kusarudza kunze kwemasero uye mukati mavo kubuda kwemashoko. Muchikamu chiduku che levothyroxine chinogadzira anabolic effect, uye pakati - kunyanya pamasukisi, masero. Mishonga ine simba rinokurudzira pamusoro penheyo yenheyo, inowedzera nzira dze cleavage uye metabolism yemakhahydrates, mafuta, mapuroteni.

Zviratidzo zvekushandiswa kwemishonga "L-thyroxine"

Mhinduro kubva kune nyanzvi pamusoro pemishonga inofadza zvikuru. Ipa mushonga wekugadzirisa kurapwa mune imwe nyaya ye hypothyroidism. Muchiitiko ichi, mamiriro acho anogona kuita etiology yakasiyana. Nokudaro, mishonga inoshandiswa kwekutanga, yechipiri hypothyroidism, mushure mekushanda pane chirwere chetrojeni kana kurapwa ne radioacod iodine, ne myxedema, kuora mwoyo pamwe chete nezviratidzo zve hypothyroidism, cerebral pituitary pathologies, cretinism. Mukuwedzera, mushonga we "L-thyroxine" (kuongororwa kwevanachiremba unotaura nezvekubudirira kwakanyanya kwechirwere) kunoshandiswa mu monotherapy ne diffuse euthyroid goiter, euthyroid hyperplasia yehutano hwehutano. Uyewo nemubatsiro wemishonga, yakaipa, yakasiyana zvikuru nehomoni-inotenderera zviremara zvehutano hwetroroid inobatwa, kusanganisira papillary uye follicular carcinomas.

Mukana wekubudisa uye kuumbwa

Mishonga inopiwa mu mahwendefa, akaputirwa mumatombo. Chimwe chikwata chemujeri chinogona kusanganisira chigadzirwa chinoshanda - levothyroxine sodium - muhuwandu hwe25, 50, 100 μg. Lactose inowanikwa munhamba yezvipindiro zvekubatsira.

Nzira yekushandisa mushonga we "L-thyroxine"

Zvipupuriro zvechiremba zvinopupurira kukosha kwekuteerera nemirayiridzo ine nzira yekutora mishonga. Zuva rose rezuva rinofanira kutorwa panguva, zvichida mangwanani, hafu yeawa vasati vadya. Muchiitiko ichi, tablet iri inofanira kumedzwa, mune zvakakwana zvakashambidzwa nemvura. Kune vacheche, kugadzirirwa kune ivhu ndokuzonyangarika mumvura shomanana kusvikira pane mafomu emhando. Kusanganiswa kwakakonzerwa kunopiwa kumwana hafu yenguva isati yasvika mangwanani ekutanga kudya (zvakakosha kugadzirira kusimiswa pakarepo musati mazvigadzirira). Mukana wemishonga "L-thyroxine", iyo nyanzvi dzinotaura kuti dzakanaka nguva zhinji, dzinorambidzwa kusarudzwa zvakasununguka. Inofanira kuiswa nachiremba, zvichienderana nezera, maitiro ehutachiona, uremu, hutano hwehutachiona, hwakagadzirirwa ne laboratory parameters. Kune vanhu vakuru, chirongwa chekutanga chekurudziro chinonzi 25-100 μg pazuva, vana 12,5-50 μg. Uyezve, yakawedzera zvishoma nezvishoma (ne25-50 μg masvondo maviri evhiki maviri), kusvikira chiitiko chekugadzirisa chinosvika.

"L-thyroxine": migumisiro

Kana ukacherechedza maitiro akaoneswa, zvinokanganisa mushure mekutora mishonga kazhinji hazvibudi. Zvisinei, pane dzimwe nguva pane zviratidzo zvakadai sekuwedzerwa kuda kudya, kushaya mafungiro basa, kupera kwemvere.

Contraindications

Usatora mishonga iyi "L-thyroxine" (nyevero dzevanachiremba dzinonyevera pamusoro peizvi, pamwe chete nemirayiridzo) muhupo hweumwe munhu hypersensitivity kuiswa muzvikamu, ne thyrotoxicosis, mwoyo rhythm disorders, angina, pericarditis, myocarditis, pazera remakore makumi matanhatu nemashanu.