"Nimid" (gel) mirayiridzo kushandiswa, rondedzero rekugadzirira

Kugadzirira "Nimid" nenzira dzakasiyana chipimo chemushonga siyana chokuita nonsteroidal Anti-anogumbura vamiririri vane antipyretic, unonyaradza marwadzo chiito, yakashandiswa rheumatic majoini uye akapfava munyama. Its chikuru vanoshingaira chirungiso ndiwo marwadzo nimesulide.

Yakabudiswa neZvapupu Indian zvinodhaka "Kusum Healthcare Pvt. Ltd ".

mhando zvinodhaka

The medicament "Nimid" kugadzirwa yakasimba, mvura, nyoro chipimo chemushonga chimiro:

• monocomponent mapiritsi nekuti ingestion;
• Forte bicomponent Mahwendefa kuti ingestion;
• granular upfu nokuti nomumukanwa kushandiswa;
• gel kushandiswa zvekunze;
• kuturika nokuti nomumukanwa yaitonga.

Kwakajairika kusunungurwa Mahwendefa ane ayo anoumba 100 MG kuti nimesulide. Vari mumapepa mukati Maronda akasiyana zvezvimedu 10, dzaizara mu packs it zvemahwendefa 10, 30 kana 100.

Mahwendefa "Nimid Forte" kugadzirwa "New Life" (India) ayo sezvamunoita vanoumba zviviri vanoshingaira zvinoriumba: nimesulide mune imwe mari 100 MG uye tizanidine hydrochloride, yakaenzana 2 MG tizanidine. Ivo mumapepa ari Maronda akasiyana zvezvimedu 10 uye rakazara mwanda №10. Itai mazhinji chiito.

The medicament "Nimid" - granulated upfu - mumapepa kupinda sachets 2 d In nechimwe chipimo chemushonga chikwata rine 100 MG ose nimesulide. Sale mushonga "Nimid" (granules) 30 sachets ari rongedza.

Gel nokuti kunze kushanda rine kwayo Zvinoumba nimesulide 10 MG muna 1 g zvinodhaka. Kazhinji ichi chikanganiso chipimo chemushonga fomu atumidzwa mafuta "Nimid". Prepacked gel ari sepombi 20, 30 uye 100 g, rakachengetwa mwanda.

Oral kuturika 1 Rine mamiririta rine 10 MG kuti basa chirungiso. Achibudiswa ndiro 60 Rine mamiririta.

Sezvo mushonga mabasa

The mashandiro chiito rinoreva "Nimid" (gel) kushandisa mirayiridzo inobatana pharmacological zvechadenga yezviri fuma. Nimesulide anokwanisa anesthetize, kudzikisa tembiricha uye kuderedza anogumbura kwendangariro. Ichi asiri steroidal Anti-anogumbura mumiririri. Its makemikari payakavakirwa harina rimwe carboxyl boka.

Nimesulide anokwanisa zvokusarudza tunodzivisa cyclooxygenase mhando 2 prostaglandin zvinhu kukanganisa kwetunhu uye leukotrienes. Anti-anogumbura nezvinozoitika nokuda chinovhiringidza pamusoro histamine yokusunungurwa kubva rechikepe mumasero, chinovhiringidza pakati paumbwe chikonzero anokonzera activation pakati platelet masero, masero bundu necrosis chikonzero. Mishonga hazvirevi synthesized bradykinin uye cytokines, ivo marwadzo, zvinoita kuti marwadzo mugumisiro yezviri fuma.

Medicine "Nimid" (hwendefa) wakatsigira-kusunungurwa unotora mhasuru relaxant tizanidine hydrochloride pamwe nechepakati chiito. With Kupindura ake hwakaipa hunenge polysynaptic dzepanguva arc ari musana, tsandanyama inzwi kuchinja. Tizanidine Unotsigira chenjera zvinorwadza kwetsandanyama kana chirwere ane musana uye chepfungwa mavambo.

Chinokosha mahwendefa yezviri chirungiso kukwanisa kuderedza paumbwe superoxide anion-kukuru kukuvadza mapuroteni nesimbi-nesurferi zvemichindwe. Izviwo, unochengeta zvinyama uye makemikari akawanda kubva rokukoromorwa pasi.

kuti anobata

Rinoreva "Nimid" (gel) kudzidziswa Chinyorwa anokurudzira kushandisa kurapa kwose chinopedza uye anogumbura maronda ari zvetsandanyama nemapfupa hurongwa. Rinoshandiswa topically mu edema uye marwadzo muchiridzira RA, RA, psoriatic chearthritis uye gout, ankiloziruschy spondylitis, osteoarthritis, Reiter kuti urwere, myalgia, tendonitis, myositis, tenosynovitis.

The mushonga inobata radicular chirwere muna osteochondrosis, lumbago, musana marwadzo, neuralgia, multiple sclerosis, palsy, sciatic tsinga kuzvimba chinopedza zvirwere musana. Inoshanda gel kuderedza kuzvimba wakapfeka munyama pakukuvara chokuita atsamwira uye kukuvara nemarunda, kukuvara ndichinanavira zviri tsandanyama fibers.

Medicament "Nimid" (Mahwendefa, granules uye kuturika) rinoshandiswa kubvisa zviratidzo kurwadziwa mapfupa, mapfundo tsandanyama chokuita osteoarthritis, dzinonzi rheumatoid arthritis, bursitis, tendinitis, myalgia.

Unonyaradza marwadzo ehupfumi kwegadziriro rinoshandiswa post-zvinorwadza uye post-kushanda marwadzo, gynecological zvirwere (chikuru algodismenorei, adnexitis), zvirwere pfava uye matambudziko mazino pachena kuzvimba uye kurwadziwa.

Antipyretic chiito zvinobudirira kunobvisa fivha zvirwere vaikudzwa kufema turakiti uye yokumusoro kufema turakiti.

Kushandiswa mahwendefa

The medicament "Nimid Forte" yakasimbisa kusunungurwa rinoshandiswa kwete usina chawadya pashure ingestion, vamwe mvura.

zvirwere Rheumatic chinopedza dystrophic zvirwere zviri zvetsandanyama nemapfupa emuviri uye chetsinga nezvirwere vabatwe pasi zano: rimwe piritsi mangwanani uye rimwe - manheru.

Kubvisa marwadzo ari tsandanyama spasm vakuru kugadza-nguva nhatu negashiro 1 piritsi. The chipimo chemushonga uye nguva kurapwa kunogona dzakachinjwa chiremba, zvichienderana mwero chirwere.

Kurwadziwa kushoma kana pashure pokuvhiyiwa anobvisa mahwendefa mukati 5 mazuva. Kana nezvinozoitika zvishomanana, zvaida kusarudzwa mumwe zvinodhaka.

Mumwe-chinoumba "Nimid" piritsi kupinza pashure pokudya kwemangwanani uye kudya nokuda 1 yori. mazuva anopfuura 15 kwete. Inofanira kushandiswa vana makore 12.

Kushandisa imwe kuturika

The kuturika "Nimid" kunwa pashure zvokudya. Nokuti vakuru, nezuva dose iri 100 MG. Kufadza daily dose haafaniri kupfuudza 400 MG, rakakamurwa matanho maviri.

Babies pashure pemakore 12, mushonga ari kumisa zvinopa zuva chipimo chemushonga pamusoro 1,5 MG pa makirogiramu muviri uremu tsoka mbiri. The kunonyanyisa dose varwere duku pazuva haafaniri kupfuudza 5 MG pa makirogiramu muviri uremu. The mirayiridzo kushandiswa yakaratidza kuti pashure pemakore 12 vana yairema makirogiramu anopfuura 40 ushandiswe dose 100 MG, yakakamurwa mumatanho maviri. Kufadza zvinobvumidzwa nhamba nimesulide haafaniri kupfuudza 200 MG.

Kushandiswa gel

Nokuti kunze kushandiswa mumiririri "Nimid" (gel) pamusoro pokushandisa muperekedzi unotora kushandisa kuti njodzi nzvimbo mbiru gadziriro, wakareba anenge 3 cm. Zvadaro zvakanaka smudge zvinodhaka mhiri ganda pamusoro kuti dziome. Per zuva kwakadaro nzira rinoitwa 3 kusvika 4 nguva. The ganda nzvimbo murwere anogona kuiswa mumiririri zvinofanira kuva zvakachena uye yakaoma, chete panyaya iyi.

Mushure kushandisa gel "Nimid" varwere siya wongororo vainyanya akanaka. Hazvina kunyanya zvakabatsirawo mavanga. With payo, nokukurumidza Unotsigira marwadzo, nyoro zvinyama edema, ukama mugove nokukurumidza regenerated masero unotungamirira nokuporesa njodzi chikamu. Vanhu vakawanda vanotambura kakawanda kukuvara, mavanga, sprains uye tsandanyama gel "Nimid" rinogarova mushonga cabinet.

Kana kunzwisisa dambudziko rheumatic zvinoratidza zvinodhaka rinoshandisirwa nzvimbo njodzi muhudyu, izvo zvinoderedza kuzvimba.

Zviduku kuti mushonga "Nimid gel" mutengo (kubvira 160 kusvika 180 rubles muzana rongedza), zvichiita kutenga kutenga akawanda.

Kushandisa granules

Chimwe chimiro wokugadzirira nomumukanwa Kutarisirwa zvinoda kufanogadzirira.

The medicament "Nimid" (upfu) asati kushandiswa mirayiridzo kushandiswa anokurudzira kuti mudutu mvura inodziya. Kubva imwe sachet arashirwa kuva girazi granules nemvura (200 ml Urume) uye akamutsa wokuparadza zvinodhaka. The yakavhenganiswa mhinduro pakarepo kunwa.

For vakuru vana makore 12 zvinodhaka raitongwa mune chipimo chemushonga 100 MG, iyo yakafanana sachet, 2 kanomwe pazuva pashure zvemangwanani uye chisvusvuro. Ya kurapwa haafaniri kupfuudza mazuva 15.

sequela pasingadiwi

Kushandisa "Nimid" chinodhaka ari granules kungaita kuti nenjodzi:

• dehwe mapundu, pruritus, urticaria, angioedema, kashoma - epidermal necrolysis, Stevens-Johnson urwere;
• kuda kurutsa, zviratidzo kurwadziwa mudumbu, kupatira, fufune, kashoma - a peptic urikanwi 12 duodenal urikanwi uye gastric, intestinal ropa, urikanwi perforation;
• kuti kuchinja transaminase basa, kashoma - kuti rikwanise chiropa;
• kuti Hope, dzungu, nomusoro;
• kuderedza uwandu weti, edema, kashoma - ane kukwana itsvo kushanda uye yavaive ropa iri weti;
• kashoma - kuti ropa iri thrombocytopenia uye nhamba vakawedzera kubva megakaryocytes;
• Kashoma - anaphylactic siyana pamwe bronchospasm, dyspnea.

Kushandisa "Nimid" mushonga mu hwendefa chimiro uye kuturika kungaita kuti zvinotevera divi siyana:

• dehwe mapundu, pruritus, erythema, wakawedzera vangadikitira, dermatitis, kashoma - kune angioneurotic edema, erythema multiforme, edema pamusoro pechiso musoro, urticaria, epidermal necrolysis, Stevens-Johnson urwere;
• kuti kurwadza zviratidzo mudumbu, kuda kurutsa, kupatira, fufune, flatulence, kashoma - dema Semi-mvura chetsoka ane munhuwi yakaipa, stomatitis, munhu peptic urikanwi 12 duodenal urikanwi uye gastric ropa iri zvomudumbu turakiti;
• kuti cholestasis, jaundice, rokuchinja transaminase basa, kashoma - kuti rikwanise chiropa;
• kuti Hope, dzungu, kutemwa nomusoro, non-anogumbura pfungwa maronda;
• munhu retsinga, kufunganya, kurota zvinotyisa;
• nokuti dysuria, edema, kusunungurwa ropa iri weti, Urinary chengetedzo, ndiyo kashoma - ane kukwana itsvo nerevane interstitial nephritis ;
• yakawedzerwa uwandu eosinophils, kuperevedza Chizenga, kashoma - kuti ropa iri thrombocytopenia uye nhamba yakawedzera kubva megakaryocytes, hypoplastic ropa masero ari hematopoiesis, platelet kushaikwa, ropa;
• kune anaphylactic kugwinha;
• kuti kupfupika mweya, kashoma - kuti bronchospasm, Árbol asima;
• kuti vawedzere kumanikidzwa, kuwedzera marwadzo kakawanda mwoyo tsandanyama, kashoma - kuona Tidal kusiyana-siyana kwezvinhu BP;
• kune asthenic ezvinhu, vanotaura nechaanoona, kuwedzera potassium muropa, kuderera mune tembiricha muviri.
• nemigumisiro kubva zvinodhaka kurapwa "Nimid" (gel) kudzidziswa Chinyorwa rinotsanangura izvi: peeling ganda, kuvaviwa, mapundu pa nzvimbo chikumbiro.

In Muzviitiko zvakaipisisa, izvo chaizvo kashoma, anaphylactic kuitike, vaine vasomotor rhinitis, angioedema, bronchospasm, kufema nenhamo.

kurapwa Izvi contraindicated

Havasi vanhu vose vanogona kushandisa zvinodhaka "Nimid" iri granules, mapiritsi kana ari muchimiro kuturika. Contraindications ndiwo:

• peptic urikanwi chirwere 12 duodenal urikanwi uye dumbu iri rikwanise Danho;
• akaratidza chiropa munhu anoshanda kana paine hepatic kukundikana;
• hepatotoxic siyana pavakanzwa zvinoumba mushonga kare;
• chakakomba kusagadzikana itsvo, kana akaratidza paminiti idukusa 30 Rine mamiririta creatinine;
• mawa negashiro zvinokuvadza zvinodhaka kuti chiropa;
• zvinogoneka ropa;
• kukundikana mwoyo mhasuro;
• Hypersensitivity kune nimesulide nezvimwe zvinoumba ari Pfungwa;
• pamuviri;
• achiyamwa;
• Vana kusvika zera makore 12;
• udhakwa kana kupindwa muropa;
• nefivha uye dzihwa-kufanana nehurumende;
• Possible kuvhiya zvokurwara.

Gel "Nimid" harina kushandiswa:

• hypersensitivity kune nimesulide nezvimwe zvinoumba ari Pfungwa;
• kana paine dermatitis, hweHIV kana kukuvadza ganda iri pachena nzvimbo;
• Árbol asima nokuda kwokubatsira acetylsalicylic asidhi;
• Children pasi pemakore 12 okuberekwa;
• Pamuviri, Third Trimester.

analogs

Chepakutanga chinodhaka pahwaro nimesulide anonzi "Mesulid" zvinoberekwa Irish kambani "Helsin Bireks".

Drug "Nimid" analogues pakati generics, kuburitswa pachishandiswa yepakutanga. Huru chinzvimbo anoreva zvakafanana zvinodhaka zvakadaro "Nimesil", "Nimegesik", "Remiksid" "nimesulide" "naiz", "Nimid Forte".

Producer rinoreva "Nimesil" ndiyo "Lab Guidotti Spa" (Italy), kunyange mushonga inowanika pamusoro Spanish kambani "Laboratorios Menarini SA". The Zvinoumba mahwendefa ane nimesulide vanoshingaira fuma iri mari 100 MG, iyo inesungano vasiri steroidal Anti-anogumbura zvinodhaka ari mukirasi sulfonanilides.

Analog inzira "Remisid" kugadzirwa FF "Darnitsa". Yakabudiswa mune imwe gel muchimiro kuti zvokunze nokushanda 10 MG nimesulide tigutsikane muna 1 g zvinodhaka. Zvinonzi rakashandiswa pakurapa pathologies yacho locomotor hurongwa.

Indian fanano "Nimegesik" mugadziri "Alembik Limited" anogadzirwa muchimiro granules kuti mhinduro kana kuturika kuti nemumuromo kutarisira suspensions, dispersible mapiritsi, suckable uye soluble mumvura.

Russian analoginen medicament "nimesulide" kugadzirwa ne JSC "Pharmaceutical Company" Obolenskaya "anogadzirwa muchimiro mahwendefa ane chipimo chemushonga 100 MG ose nimesulide. muiti Izvi Anti-anogumbura, unonyaradza marwadzo uye antipyretic kushanda nenzira dzakasiyana-pathological pezvakaitwa skeletal uye zvinyoronyoro nyama dzemuviri.

Kugadzirira "naiz" kugadzirwa ne "Dr. Reddy kuti Laboratories Ltd." kugadzirwa kwakajairika uye dispersible mahwendefa, mumwe kuturika nokuda nemumuromo kutarisira ari muchimiro gel kuti zvekunze kushanda.