Oncomarker CA 125

CA 125 inofungidzirwa kuti yakakura maseroyumu glycoprotein, iyo inonzi antigen. Izvo zvinoitika kubva kumashure mune coelomic epithelium ye fetal tissue uye inowanikwa mumagetsi mumagetsi ekupedzisira, mucinous uye serous uterine fluid. Muropa, hazvipindi, kunze kwezviitiko zvekuparadzwa kwezvipikiso zvepanyama.

Kuisa mukati me serum kunogona kuwedzera kaviri panguva yekuenda kumwedzi, kunyanya maererano nechekupedzisira kwe endometriosis. Iko CA 125 inogona kuwedzerwa pamutambo wekutanga wekuita pamuviri. Kuwedzera zvishoma kumudzimai ane hutano kunokonzerwa nekushandiswa kwaro mumunyengetero, chivako chemuviri, bhonical epithelium, pericardium, fallopian tubes; Muvarume - nekutanga mu epithelium ye testes.

Kujekesa chaiyo CA 125 inogona kuona mastasimasi yechipfupa mwedzi mitanhatu isati yatanga kusvika kwechirwere chekuratidzira (kuratidzwa). Izvi zvinoita kuti zvikwanise kuongororisa zvinoitwa mukurapa kwechirwere ichi.

Icho chikwata cheCA12 125 chinonyanya kukosha pakuongororwa kwekenza yevana. Kuongorora kunobva pakuonekwa kwekuwedzera kwemaantijeni muropa. Zvinhu izvi zvinoratidza kukura kwechirwere. Mamwe antigens anosanganisira mamwe mahomoni, enzyme, maitiro ekuora kwemamota uye vamwe.

Kuongorora kweOncomarker chaiyo CA 125

Chimiro chechiratidzo chacho majekiti 35 / ml. Kuwedzera kwehutano hwekuregererwa (kuderedza) kunoonekwa sechikonzero chekuongorora kwakadzika kwomurwere kuitira kuti aone kudzokorora kwehutano. Kuwedzera nguva dzose kwehutano kunoratidza nzira inofambira mberi yehutachiona hwekuita uye kusarudzwa kwakaipa kune kurapwa.

Kuongororwa kweecoprotein CA 125 ine zvakadzama zvakananga. Maererano nehuwandu hwemashoko, kuwedzerwa kwechipiri mumaseru, zvikurukuru kuvarwere vanopfuura makore makumi mashanu nemashanu, vane chiratidzo chechokwadi chekuvandudzwa kwekenza yevana.

Pakati pekutora mienzaniso uye yekudya kwekupedzisira, inofanira kunge iine masere masere (zvichida, zvechokwadi, kwete pasi pegumi nemaviri) maawa. Iwe haugoni kunwa tiyi, juice kana kofi. Inobvumirwa kushandisa mvura.

Kuwedzera antigen mu serum kunoratidza kenza:

- mune pancreas, iyo mammary gland;

- maovha, endometrium, uterus, fallopian tubes ;

- chiropa, mudumbu, rectum;

- mapapu;

- zvimwe zvinopesana neoplasms.

Kuwedzera kukuru kwemaharasi kunozivikanwa nezvemakumbo mumutsara wepamuviri, mukaka uye bronchi. Nokudaro, hazvibviri kunyatsoongorora chirwere pamusana peC CA 125 chete. Somugumisiro, kutsvakurudza mberi kunodiwa.

Kuwedzera zvishoma kuC CA 125 kunogona kuonekwa nehutachiona hwemasimba ehutano hwakanaka, pamwe chete nekuputira maitiro anosanganisira appendages. Kuzvirwere nemamiriro ezvinhu, pamwe chete nekuwedzera zvishoma muzinga re antigen, zvinosanganisira:

Ovarian cyst;

- endometriosis;

- kuvhiringidza muzvinyorwa;

- pleurisy, peritonitis;

- STI;

- kumwedzi;

- cirrhosis, chronic hepatitis;

- chisinganzwisisiki pancreatitis;

- Zvimwe zvirwere zvekudzivirira muviri.

Nekuvandudzwa kwemakumbo ekuremara, pamwe nekuputira maitiro, iyo oncoprotein CA 125 haina kudarika zviyero zana / ml. Mherechedzo inokosha pakuongorora nzira yekurapa inoshanda yekurapa nzira dzinoshandiswa, pamwe nekutaridzika kwekudzivirira kwekudzoka kwe endometriosis.

CA 125 inofungidzirwa sechirwere chese serous carcinoma mudumbu. Nhamba yaro ye 150-200 U / ml inoratidza kusabatanidzwa kwema-serous membranes muhutano. Zvakakosha kuongororesa maitiro ayo pakuongorora kubudirira kwekupindira nekuvhiya uye chemotherapy. Muchiitiko chechibereko chinenge chiri kure, ropa raro rinowira kumakamuri gumi pamamiriyoni. Kuwedzera kusvika mauniti 35 / ml inoratidza kudzoka kwegadziriro.