The mushonga "Gynestril": mirayiridzo kushandiswa, analogs uye wongororo

Sei kutora zvinodhaka "Gynestril"? Mirayiridzo kushandisa mushonga uyu zvichakurukurwa inorondedzerwa zvinhu ino. Mariri, ratinoparidza mhinduro wevarwere, mushonga, ayo pharmacological maitiro, zviratidzo uye contraindications.

The sezvamunoita, chimiro

Zvii zvinoumba zvinosanganisira mishonga "Gynestril"? The Mirayiro yakatora kuti nzira iyi, zviri kuti chacho vanoshingaira chirungiso ndiyo mifepristone. Uyewo medicament unotora zvimwe zvokubikisa muchimiro mbatatisi starch, lactose, microcrystalline cellulose, povidone, magnesium stearate uye yavaibvisa carboxymethyl starch.

Kutenga mishonga iyi inogona kuva pamahwandefa, izvo mumapepa ari packs it kuti makadhibhokisi.

Pharmacological unhu mishonga

Wanga uchiziva kuti ari chinodhaka "Gynestril"? Mirayiridzo dzokushandisa richakubatsira kunzwisisa zvinofanira kuitwa zvinodhaka ichi, uye vachakuudza kuti pasi hapana zvinoratidza kushandiswa kwaro okurapa.

Viewed medicament chinhu steroid mumiririri antigestagens chakaita zvokugadzirwa mavambo. The kuchirapa efficacy zvinodhaka nokuda kwayo sezvamunoita.

Pamusoro okutambirwa mifepristone ari mumuviri womunhu kuchititadzisa migumisiro progesterone, asi asingaiti kuratidza progestational basa.

Nyanzvi ona daka zvinodhaka nokuda kukwikwidzana glucocorticoid tichisunga panguva Kanotokonya pamwero.

Sezvo chikazozikamwa, chikuru basa paumbwe uterine leiomyoma wakapiwa mukadzi mahormone, zvikurukuru progesterone. Panyaya iyi, mifepristone unogona kupiwa murwere kuti adzikatidza progesterone Kanotokonya. Somugumisiro kurapwa ichi kunoitika bundu kukura kunonoka, uyewo kuderedza kukura fibroids , uye uterine.

The pharmacokinetic ehupfumi zvinodhaka

Zvii ane pharmacokinetic zvinodhaka "Gynestril"? Instructions, nhoroondo noruzivo vanachiremba vanoti kuti pashure nomumukanwa Kutarisirwa chepamusorosoro wevasungwa zvinodhaka riri akacherechedza munenge 80 maminitsi. Uyezve, ayo bioavailability ndiyo 69%.

Plasma mapuroteni vaiona zvinodhaka anosunga kusvika 98% (pamwe sealbumin Alpha-1 iine acid glycoprotein).

Mushure Kuparadzirwa danho kunoitika kunonoka kubviswa danho. Muropa wevasungwa zvinodhaka ipfupi nehafu (pakati maawa 15 uye 72).

Kubviswa pakati zvinodhaka riri nokukurumidza, ane nguva maawa 18.

zvairatidza

Kubva izvo zvinodhaka "Gynestril" anogona kupiwa? Mirayiridzo yokushandisa, nyanzvi chaidzo anoratidza zvinotevera zvairatidza:

• Mabatirwo uterine leiomyoma;
• kugumiswa intrauterine pamuviri kusvikira mazuva 42;
• induction (kana kurudziro) okushanda (kusanganisira pa izwi);
• nhumbu chimbichimbi (postcoital) nokuti unreliability akashandisa pamuviri, uye munguva pashure kudzivirirwa zvepabonde.

Contraindications

"Gynestril" mushonga kuti pamuviri harifaniri kushandiswa kana:

• akaora unconfirmed pamuviri;
• bvumidzwa ectopic pamuviri;
• pamuviri iyo akamuka pashure caffeine pamusoro hormone pamuviri nzira, kana muchishandisa intrauterine pamuviri;
• pamuviri mushure memazuva 42.

Kana leiomyoma mushonga uyu hakubvumidzwi kuti ndipe zvinotevera nyaya:

• achiisa panguva submucous myoma nodes;
• mu ovarian anomera;
• endometrial hyperplasia isiri yekenza;
• kana leiomyoma mutengo wakakura.

"Gynestril" Tablets kuti induction basa harina kushandiswa:

• zvakakomba preeclampsia;
• kanganisika fetus mharidzo;
• pre-eclampsia;
• eclampsia;
• preterm kana post-rokuti pamuviri;
• imbalances kukura fetus musoro uye vanamai chiuno;
• undiagnosed kusvibisa kubva dzokubereka turakiti panguva gestation.

Ko mukuru contraindications zvinodhaka "Gynestril"? Mirayiridzo anopa mubvunzo uyu kutsigira. inorambidza izvi zvinosanganisira zvinotevera ezvinhu:

• porphyria;
• Kwenguva refu kurapa pamwe glucocorticoids;
• zvakakomba kupererwa neropa;
• renal kana chiropa kukundikana (chero chimiro);
• zvaipesana hemostasis (kare anticoagulant kurapwa);
• extragenital chakakomba;
• zvokurwara munhukadzi dzokubereka nadzo, kuri anogumbura hunhu;
• hypersensitivity (kusanganisira nhoroondo);
• nikotinozavisimost, kunyanya pashure pemakore 35.

Nokungwarira yokunyanyisa kana kutora mushonga ichi:

• obstructive pulmonary zvirwere (chirwere hunhu);
• mwoyo kutadza;
• neBP;
• arrhythmia;
• Árbol asima;
• mwoyo mutinhimira vachivavhiringidza.

Drug "Gynestril": okuti

Nokuti kugumiswa pamuviri (murefu wongororo kuti medicament ichi ichakurukurwa zvishoma mberi), mushonga uyu anofanira kupiwa chete rakamanikana nyanzvi. Uye rambai kutora mahwendefa iyi chete pamberi imwe gayinakorojisiti.

Sezvo kushandisa zvinodhaka "Gynestril"? Mirayiridzo pamuviri kugumiswa inoti kuti zvakakosha kushandisa chimwe dose pamusoro MG 600.

The mushonga chinobviswa pamusoro maawa 1-1.5 pashure zvokudya uye ndikandoshamba pasi 100 ml mvura.

Kuwedzera efficacy zvinodhaka arege mberi chinangwa 400 MG misoprostol (i.e., a chakaita zvokugadzirwa prostaglandin E1).

Pashure pokugamuchira Mahwendefa murwere zvinofanira kutarisirwa obstetrician maawa dzinenge mbiri. Shure kwamazuva 1.5 kana 2 vakatakura Ultrasound. Kunyange pashure pemavhiki 1-2 kuitisa kunotoda kuongororwa uye akadzokorora Ultrasound uye kuongorora ropa kwevari hCG kuzosimbisa kupfupfudzika.

Pakadaro, kana mushonga havana kubatsira (kureva, pamuviri mberi), chiremba anokurudzira munhu Vacuum chido mamwe kudzidza (histology) migumisiro nzira.

Kuti inotokonya Generic mabasa, mushonga kamwe raitongwa ari chipimo chemushonga vana 200 MG. Vanoita izvi pamberi imwe gayinakorojisiti. Pashure zuva rimwe, iro dose kurapwa inodzokororwa nenguva dose.

Pashure pemazuva 2-3, kufungidzira riwedzere kubereka Canal. Zvanzi kuona mukana kwohumwe kushandiswa "Oxytocin" kana prostaglandins.

Kana uterine leiomyoma zvinodhaka "Gynestril"? Guide anoti kana kugadzirira chirwere chakadai kazhinji chinotarisirwa mune rimwe dose 50 MG. The mushonga chinobviswa nomuromo kwemwedzi mitatu.

Panyaya post-coital nhumbu, vanachiremba vanoti kushandiswa vaiona medicament mune mari 10 MG mazuva matatu mushure kudzivirirwa zvepabonde (zvisinei kumwedzi kutotanga). Kutora mapiritsi mune iyi zviri zvinodiwa kwemaawa maviri asati kana tapedza kudya.

zviitiko ovhadhozi

Kushandisa zvinodhaka ari dose vasina magiramu anodarika maviri zvinokonzera chero Migumisiro. Kana kushandisa kupfuura yakanatsa chitsama mishonga murwere anogona kuumba adrenal insufficiency, chinoda symptomatic kurapa.

nemishonga

Kugamuchira medicament "Gynestril" kunowanzokonzera zvakadai nemishonga sezvo nemusoro, kuda kurutsa, dzungu, kurutsa, mapundu, manyoka, amenorrhea, lohiometra kusvibisa, uterine subinvoljutcija, hyperthermia, emmeniopathy, utera, kuora mwoyo pamusoro kuzvimba dumbu uye zvinoshandiswa, kusagadzikana uye kurwadziwa mudumbu. Kana mukawana zviratidzo izvi, iva nechokwadi kuti chiremba.

zvinodhaka kwavatori

Hazvina yakarumbidza kutora zvinodhaka "Gynestril" iri kufanana NSAIDs. Zvinofanira kucherechedzwa kuti akabatana glucocorticoids Zvakakodzera kuwedzera dose, asi chete mushure mekubvunza chiremba wako.

chaizvo kurumbidza

Hazvina yakarumbidza kutora mushonga sezvo nguva pamuviri.

Kana iwe kushandisa "Gynestril" Pamuviri vanofanira nguva dzose zvapinda murwere pamusoro dzimwe nzira nzira iyi, kunyanya kana pashure pevhiki mbiri pamuviri mberi kana pane kukwana pamuviri (zvichiita mukana abnormalities ari mudumbu).

Price uye analogues mari

Analogs "Gynestril Kutarisirwa kwezvinhu" zvinodhaka ndedzinotevera mishonga: "Ginepriston", "Penkrofton", "Agesta" "Mifepristone", "Zhenale", "Mifolian", "Mifegin", "Mifepreks", "Miropriston".

Price vaiona mishonga chaizvo uye yaiva 5000-6000 rubles.

Reviews kuti medicament

Inonzwisisika uye akananga akanaka kana akaipa nezvokubatsira "Gynestril" hapana gadziriro. Zvisinei, varwere vakawanda vanoteerera pamusoro chokushandisa ichi. Vanoti kuti inoshanda chaizvo uye njodzi nokuda mabiko.

Zvinofanira kucherechedzwa kuti vamwe vanhu, nekusiyana, kazhinji pasika kukura nemishonga.

Wongororo zvose izvi zvinoratidza kuti kudya mishonga iyi zvinofanira kuitwa chete pashure zano chiremba.