The mushonga "Prosulpin": mirayiridzo manual, wongororo uye analogues

Medicine "Mirayiridzo Prosulpin 'kushandiswa iri papi somunhu simba antipsychotic mushonga kuti rinoshandiswa pakurapa zvirwere zvakasiyana-siyana tsinga uye zvimwe zvirwere. Zvakawanda pamusoro pekugadzirira pamusoro apa, verenga mberi.

tsananguro pfupi kwegadziriro

mushonga uyu ndohwaJehovha boka kuchiiswa -benzenamine. Mune imwe nzira, tinogona kutaura kuti chaiwo antipsychotic zvinodhaka "Prosulpin". Nyanzvi Guest anoratidza kuti chinhu chacho nechinangwa ichivharira dopamine receptors (D2i D3). Nokuda chambotaurwa nezvacho antipsychotic zvinodhaka unobereka muviri chaizvoizvo.

50 kana 200 MG rimwe piritsi rine sulpiride "Prosulpin" gadziriro.

Marwadzo kana kutora mushonga, Chokwadi, anowanikwa mune zvimwe zviitiko. Saka, mumwe murwere paaiita mishonga kupfuura antipsychotic kunofanira pasi kuzviomesera zvokurapa achitarisirwa.

mushonga uyu ane dzakawanda. Inowanika hwendefa chimiro uye muchimiro capsules, mhinduro intramuscular Kutarisirwa uye mvura kuti ingestion.

The mushonga zvinofanira kuchengetwerwa panguva dzekudya kamuri tembiricha asi kwete kupfuura 25 Celsius. Nzvimbo inofanira zvakanaka kuchengetedzwa kubva chiedza uye unyoro. Inenge maviri makore pasherefu upenyu "Prosulpin" chinodhaka. Analogues hazvina kuoma kuwana. Medicines pamusoro pamusika zvakawanda Sevamiririri zvinodhaka dzataurwa pamusoro apa.

The pharmacological zviito wo kuchirapa mumiririri

Medicine "Prosulpin" vane mufananidzo inopiwa pazasi, chinhu antipsychotic mumiririri ari neuroleptic. sulpiride fuma nokuda ichivharira pamusoro dopamine receptors mu tuberoinfudibulyarnoy nharaunda kunoita kuwedzera prolactin mumatunhu. Zvinofanira kucherechedzwa kuti kuwanda 60-80% dhigirii dzinosiyana-siyana ichivharira dopamine receptors.

Ekupedzisira dzinosiyana zvakakwana yakakwirira kufanana kuti benzamide, inova maitire akadai zvakakurumbira sezvo bifazicheskoe zvainoita neurotransmitter dopamine hurongwa. Mukuwedzera, ivo adzikatidza kuwedzera synaptic dopamine usage nharaunda, i.e. venga presynaptic auton Kanotokonya D2 D3.

Zvinofanira kucherechedzwa kuti apa Pfungwa iri zvine mwero neuroleptic basa. The yokupedzisira unobatanidzwa nomumwe timoanalepticheskim uye anoita zviito chokushandisa.

The pamusoro chinodhaka ane zvinotevera pharmacological Migumisiro:

• antiemetics (dopamine Kanotokonya blockade rinoitwa rukungiso kurutsa pakati mapazi);
• antidepressant;
• antipsychotic.

Sulpiride inoratidza antidepressant migumisiro pa mishonga anosvika 600 MG. Above urongwa uhwu zvakatojekeswa akacherechedza antipsychotic nemigumisiro zvinodhaka ichi pamusoro muviri.

Mukuwedzera, zvinodhaka "Prosulpin" mirayiridzo kunoratidza izvozvo pave nomugumisiro zvokusarudza pamusoro hypothalamus, zviratidzo gastric urikanwi uye gastroduodenitis. Saka woutsinye yakakwirira excitation nzvimbo yacho tsitsi tsinga, kunonatsiridza ropa wedzerai mudumbu, nokukurumidza yokuwedzera granulation rinenge riri dzinotsanagura madzihwa secretion mudumbu, aumbwa regenerated epithelium, nekutarisa kushandiswa nekuwanda capillaries kunonatsiridza tishu.

Ndiani anofanira kutora mushonga uyu?

Chii kuti zvinodhaka "Prosulpin" zvairatidza? For kuchirapa zvinangwa, pamusoro apa zvinodhaka zvinoshandiswa zvirwere zvakadai:

• psychosomatic zvirwere;
• kunetseka nemaronda of zvomudumbu turakiti;
• symptomatic maronda;
• gastroduodenitis;
• nomudumbu. urikanwi;
• tsamwa bowel (muura);
• medicated maronda;
• nonspecific maronda colitis;
• Depression siyana Mabviro;
• netsinga;
• reactive mwoyo;
• dysphoric nyonganyonga;
• schizophrenia;
• chisingaperi chirwere chepfungwa ;
• migraine;
• chenjera vairwara nepfungwa;
• vertigo dzakasiyana Mabviro (vestibular neuritis, vertebrobasilar insufficiency, basilar, chirwere Meniere vake, otitis nhau).

Drug "Prosulpin" mirayiridzo kushandiswa anoda kushandisa kuti pakurapa maitiro asina kutsarukana uye psychoses muvarwere vaduku, kureva vana. Izvi zvirwere zvakadai kuzvikuvadza, nokusagadzikana, pfungwa. Uyewo mushonga "Prosulpin" mirayiridzo kushandiswa akaomerera rinokurudzira kushandisa sechikamu nzira yokurapa ose infantile autism. chokushandisa ichi chinoshandiswa kurapa varwere vechiduku vane makore 6 makore.

Contraindications pakushandisa chambotaurwa nezvacho zvinodhaka

Drug "Prosulpin 'mirayiridzo kushandiswa haina yakarumbidza kana murwere ane zviratidzo zvinotevera zvirwere:

• hypersensitivity kuti zvinodhaka;
• hyperprolactinemia;
• prolaktinzavisimye mapundu (kenza yemazamu, pituitary prolactinoma);
• zvinyamusi;
• chenjera chepfu kunwa kuti ane doro;
• kwakakasharara;
• pheochromocytoma;
• Chenjera chepfu nezvinodhaka kana zvinodhaka avete mapiritsi;
• nemanic psychosis.

inoti zvose izvi zviri kuomesa contraindications. Uyewo mushonga "Prosulpin" mirayiridzo kushandiswa nekudzivisa kupa nevakadzi kwokuyamwisa mwana wavo, vana pasi pemakore 18 (nokuti 200 MG mapiritsi), varwere vaduku kusvikira 6 makore (50 MG mapiritsi).

Uyezve, zvinofanira kuyeukwa, zvakare zvisingadiwi kushandisa zvinodhaka "Prosulpin" vachiberekwa kushayiwa lactose, shuga-galactose malabsorption, lactose kusashivirira. Contraindications pakushandisa pamusoro kuchirapa yomuchipatara anoshandawo kuvakadzi pamuviri. Chishandisei varwere akadaro anobvumirwa chete kana kutarisirwa zvikomborero zvinodhaka achava yepamusoro zvikuru kupfuura zvingakanganisa azvarwa kubva kwaari.

nemishonga

Kana kugamuchira "Prosulpin" gadziriro (Chinyorwa inoratidza ichi), unogona kuona imwe nemishonga:

• pamusoro chikamu kwemakemikari anobudiswa hurongwa - galactorrhea, dysmenorrhea, amenorrhea, frigidity, kusabetsera;
• kubva tsinga - nyaradzo, chakamira pakunodengenyeka zvine, dzungu, mangwanani dyskinesia, extrapyramidal urwere, somnolence, akinesia pamwe tsandanyama hypertonicity, akathisia, motokari excitation;
• kuwedzera basa makemikari (kubva kugaya);
• hemolytic kupererwa, leukocytosis, aplastic kupererwa neropa, granulocytosis, purpura, thrombocytopenic kuitika dzakakwirira mishonga "Prosulpin" gadziriro (by Zvakaitwa ropa uye node nehurongwa);
• tachycardia, orthostatic hypotension, ungaderedza kana yakawedzera BP, nezvishoma kuti chinguva QT, mune zvimwe zviitiko kukura kwezvirwere ngozi zvakadai torsade of pointes syndrome (mwoyo wayo maitiro).

Anokonzerawo mhiri migumisiro zvinodhaka ichi. Drug "Prosulpin" (mirayiridzo apindure vanachiremba uye varwere mhinduro anopupurira ichi) kungakonzera zvakadai zvisingafadzi mananara sezvo tardive dyskinesia, iyo inozivikanwa nokuva involuntary mutinhimira fambisa kumeso kana rurimi (ane refu kuchirapa kosi neuroleptics mapoka zvose), hyperthermia. Nyanzvi kuyambira kuti mukupera nyaya iri kunyanya kukosha nguva kubvisa pamusoro nzira, sezvo tembiricha vosimba angava anoratidza zvirwere zvakadai ngozi zvakadai neuroleptic akaipa syndrome.

Kufuta, wakawedzera vangadikitira, ganda mapundu uye kuvaviwa - zvose izvi marwadzo kukonzerawo zvinodhaka "Prosulpin". Instructions, mhinduro kubva nyanzvi dzinokurudzira Muzviitiko zvakadaro kurega kunwa mushonga pamusoro uye kutsvaka chiremba nokukurumidza wezvokurapa rubatsiro uye zano.

Shandisa panguva pamuviri kupfuura kuchirapa mumiririri

Teratogenicity zvinodhaka haina kuwanikwa somugumisiro kuedza mhuka. Vamwe vakadzi vakashandisa mushonga panguva yenyu pamuviri, uye haana kuchengeta pamusoro-kutaurwa kushanda. Asi varwere ava vakagamuchira yakaderera-dose kukurairisai rinoreva "Prosulpin". Mirayiridzo yokushandisa, nyanzvi chaidzo havana ruzivo chaiwo maererano nokushandiswa yakakwirira chitsama ane pfuma akadai sulpiride. Panewo pasina mashoko pamusoro nokuitika chambotaurwa nezvacho Pfungwa kuti kukura fetus muuropi.

Kuti tizvidzivirire nyanzvi regai zano kushandisa mishonga iyi vakadzi rehurumende. Kunyange zvazvo dzimwe nguva, achiri kubvumira kurapwa kwegadziriro varwere-dzataurwa pamusoro apa, havana kutarisira mwana, asi zvakasimba mune usingashandi mishonga.

Nyanzvi dzinoti kana amai kugamuchira neuroleptics kurapa mazhinji nguva, achangoberekwa mafufu vaiva nezvinetso zvomudumbu turakiti basa (eg bloating).

Kana mukadzi inoshandisa mushonga panguva risati wakurukura, kudzora muviri wake uye kukura ari mudumbu nachiremba iri fanira.

Zvinofanira kurangarirwa kuti zvinoenda mukaka zvinodhaka "Prosulpin". Mirayiridzo yokushandisa, nyanzvi chaidzo regai kuvakurudzira kutora panguva lactation.

Sei kutora zvinodhaka "Prosulpin"?

Guide yavanopa varwere shandisa pamusoro antipsychotic ose 8 maawa mumwe chete piritsi. Ko yakarumbidza kutora mushonga pashure 16,00, sezvo kwayakaita zvikuru kunowedzera panguva ino. Zvinofanira kucherechedzwa kuti kushandiswa pasinei kudya akandoshamba pasi aine zvakakwana chitsama imvura gadziriro "Prosulpin".

Mahwendefa kuti ane 200 MG pamusoro sulpiride, vanogamuchirwa panguva chakasimba zviratidzo schizophrenia, delirious psychosis uye kuora mwoyo. The mushonga unogona kutorwa mazvake mishonga. Its kunonyanyisa daily dose iri MG 100, kana mapiritsi vanenge 5.

Mahwendefa, izvo zvinosanganisira 50 MG pamusoro sulpiride, anopa mirayiridzo kutora, kana murwere ane zviratidzo neurosis, mwoyo. Mukati 4 mavhiki, varwere ava vanofanira kudya kushoma mumwe uye vaifanira 3 mahwendefa pazuva.

Uyewo, mapiritsi aya anogona kutorwa vana vane kwazvo matambudziko zvounhu. Makore varwere chakadaro nguva dzose kuva kupfuura 6 nemakore. Kufadza daily dose varwere vari muchikwata ichi chinobva 5 kusvika 10 MG pa 10 makirogiramu muviri uremu.

ovhadhozi

Manual kunoratidza kuti mashoko ovhadhozi sulpiride ipfupi. Zvinotevera zvingaratidza kuonekwa ichi ari murwere:

• rurimi protrusion;
• dyskinesia pamwe spasmodic torticollis;
• madzerere;
• muromo yakaoma;
• zvinogoneka Kugadzirwa NSAs;
• extrapyramidal zviratidzo;
• zvakawedzera vangadikitira;
• svoto;
• nyaradzo;
• gynecomastia;
• Parkinson nehosha;
• wedzera BP.

Treatment ari pamusoro mamiriro murwere rinoitwa sezvinotevera:

• vaigeza dumbu murwere;
• neMutungamiriri kusashanda kabhoni;
• humwe hurongwa kurapa.

Kana zvakakodzera, muna Muzviitiko zvakaipisisa, chiremba anogona mishonga yokuwedzera kumonyanisa akadai diuresis aizomupa kugadzirisa zviri alkali kana vachiongorora kunokosha muviri mabasa.

Zvinofanira kucherechedzwa kuti gadziriro iyi rinobva pamwe mu hemodialysis.

Vamwe Mapato wevarwere vanofanira chaiwo patinoungana kushandisa "Prosulpin" chinodhaka. Uyu unechekuita kunyanya vakadzi paunowana nguva, varwere zvikuru hypotension uye BP.

Zvinokoshawo kuti varwere tsviyo rokutanga electrophysiological uye kunotoda kuzviongorora. Zvinofanira kurangarirwa kuti zvinodhaka "Prosulpin" lowers pachikumbaridzo kuti kufenda basa.

Uyezve, kana uchityaira chokufambisa kunoda kutarisirwa munguva kurapwa pamwe pamusoro zvinodhaka. Zvinokoshawo kuti tizvidzore zvinhu zvinoda nokukurumidza psychomotor siyana uye yakakwirira yevasungwa.

Kudyidzana nevamwe kuchirapa vamiririri

Instructions havana zvachose rinokurudzira kuti ichangobva kutaurwa zvinodhaka ari kubatanidzwa marapirwo pamwe levodopa. The vaviri vanoshingaira zvinhu vari mhandu. Kana murwere, anorwara nechirwere chinonzi Parkinson, zvinotoda levodopa, chiremba ndiye mumiririri anofanira kusarudzwa kuti ane usingashandi extrapyramidal migumisiro.

Arrhythmias akadai torsades of pointes kunogona kukonzerwa mubatanidzwa "Prosulpin" chinodhaka ne:

• antiarrhythmic zvinodhaka, izvo nhengo kirasi Ia (zvinodhaka "Dizopiramid" "quinidine");
• zvinodhaka "pimozide," "Haloperidol", "thioridazine" "Cisapride", "Pentamidine" imipraminovymi antidepressants;
• zvinodhaka antiarrhythmic hunoumba mukirasi yechitatu (rinoreva "Sotalol", "Kakamiodaron");
• mishonga kuti anokonzera zviratidzo zvirwere zvakadai bradycardia (Beta-blockers, karusiyamu gwara blockers);
• zvinodhaka kuti pave chimiro zviratidzo hypokalemia (laxatives kuti vari stimulatory, hypokalemic diuretics, tetracosactide, glucocorticoids);
• dopamine mhandu (antiparkinson): "apomorphine", "Amantadine" "Lisuride", "Ropinirole", "Entacapone" "Bromocriptine", "selegiline" "Pramipexole" "Piribedil");
• antipsychotic mishonga kuti anokwanisa kukonzera zviratidzo torsades of pointes ( "Chlorpromazine" "Amisulpride," "Tsiamemazin" "pimozide," "Droperidol" "levomepromazina" "tiapride," "Sertindole" "Veraliprid" "Sulpiride") ;
• zvinodhaka kuti ane lithium (ekupedzisira zvikuru kunowedzera ngozi yokubatwa extrapyramidal zvirwere).

Uyewo, chero zvazvingava, zvinodhaka "Prosulpin" harifaniri kushandiswa pachiimbwa doro. Last potentiates ari kunyaradza mugumisiro neuroleptics.

Uyezve, kana isu kutora ichangobva kutaurwa mushonga akabatana centrally unokurudzira zvinhu (Anti-asthmatics, anorectics), murwere anogona kuona zviratidzo simba excitation, kutya, kuzvidya mwoyo, kunetseka.

Zvinofanira kurangarirwa kuti antipsychotic nemishonga lowers padanho kubudirira ropinirole.

Substitutes "Prosulpin" kuchirapa mumiririri

Analogs pamusoro apa antipsychotic:

• "Betamak T100";
• "Vero Sulpiride";
• "Betamax T50";
• "Depral";
• "Betamax";
• "The dzidziso";
• "Betamax T200";
• "Sulpiride";
• "Eglonil";
• "Sulpiril";
• "Eglek".

Asi vakashandura pasina risati zano chiremba hariudzi "Prosulpin" mirayiridzo Chinyorwa. analogues wayo avo nomumwe nemishonga. Vanogona kuunza kukuvadza zvikuru kuti utano murwere.

Mhinduro zvokurapa rinoreva "Prosulpin"

Reviews emishonga pamusoro vainyanya zvakanaka. A yakawanda varwere kuushandisa muna mwoyo inoti. Vanoti bhuku iri rinobatsira kubvisa zviratidzo hosha iri anenge 100%.

Uyezve, varwere vakawanda zvakakwana mhinduro, izvo zvirwere zvakadai schizophrenia, enterocolitis, colitis, psychosis, enteritis, maronda chirwere, kutsamwa bowel chirwere, akatora zvinodhaka "Prosulpin". Reviews ose anoratidza kuti nguva dzose, kuti chokushandisa unobereka Zvaifadza kuporeswa maturo. Uyezve, varwere dzinoshuma kuti nemishonga kuitika chaizvo kashoma.

The apa mushonga une zvakakomba nemishonga, saka kurishandisa pasina risati zano chiremba iri zvachose wairambidza.