The mushonga 'third 400', mirayiridzo kushandiswa, nemishonga

"Third 400" ndiyo asiri steroidal Anti-anogumbura zvinodhaka. The rinoita fuma iri ibuprofen - rinobva pane propionic asidhi ane antipyretic, unonyaradza marwadzo, antiinflammatory Chaizvoizvo, kunoitika apo asiri kusarudza Cox blockade - 1 uye 2, uye inhibitory migumisiro iri kwetunhu prostanglandinov.

Zvazvakaita zvinodhaka sezvo mushonga unonyaradza marwadzo ane chokuita norudzi marwadzo, ine kunonyanyisa nekuomarara achirwadziwa apa kuzvimba. Antiagregatnaya basa hunhu ibuprofen, uyewo vamwe vasiri steroidal zvinodhaka.

Available mushonga ari muchimiro chena denderedzwa zvakaumbwa pamahwendefa. Mahwendefa "third 400" zvinenge zvakazara kuva maviri-nzira pangozi uye Mabhuku eBraille "E" kumativi ose. Ibuprofen pa hwendefa iri 400 MG, kunze ichi pane zvinotiyamura pakunyora "third 400", mirayiridzo rinoratidza zviri magnesium stearate, cornstarch, colloidal nesilicon dioxide, yavaibvisa carboxymethyl starch. The goko ine zvinotevera zvinoriumba: povidone K30, hypromellose, macrogol 4000, titanium dioxide.

Kufunga pharmacokinetics zvinoreva zvinogona kunzi pane chakanaka chinodhaka Absorção de Água kuburikidza nemudumbu "third 400", mirayiridzo hunoratidza yaro kunonyanyisa tigutsikane mumuviri pashure ingestion kuburikidza 2 awa zvinodhaka dzinoratidzwa 99% tichisunga kuti mapuroteni eplasma, muna synovial mvura vakaparadzira nomumugwagwa kwaitora nguva pane plasma, zvakafanana manotsi ari risinganyatsozivikanwi kuti rakabva papi.

The kinetics pamusoro excretion kuti ibuprofen ane maitikiro maviri: vaifanira maawa 3 kubva plasma, kuti weti uye bile - anenge 1% kuchinja.

Pane zviratidzo zvakawanda zvinodhaka "third 400", mashoko rinoreva zvinotevera nyaya:

- ndichinzwa zino, kutemwa;

- neuralgia;

- migraine;

- nefivhiri pamwe chikosoro;

- vadyi, tsandanyama marwadzo.

Kwakamutsa ndandanda kurutivi zvinokonzerwa zvinodhaka "third 400", mirayiridzo anopa rondedzero dzaro maererano sei munhu dzemuviri.

The zvomudumbu Hurongwa: chirungurira, dumbu marwadzo, kurutsa, kupatirwa uye manyoka, flatulence, kashoma akacherechedza kuoma uye akashatirwa ari mucous Kamudzira pamuromo.

Respiratoria maitiro: bronchospasm uye kupfupika mweya.

Kumwoyo: tachycardia, mwoyo kukundikana, wakawedzera BP.

Pfungwa: madzerere, kusanzwa, kukuvadzwa ari optic etsinga (chepfu), conjunctivitis.

CNS: nemusoro, kufunganya, kuora mwoyo, kuvhiringidzika, hope uye kushaya hope;

Uye matambudziko angamuka munyika Urinary ino panguva ingestion "third 400", mashoko anonyevera mukana cystitis uye rikwanise renal kukundikana, edema uye sema nephritis.

Kungava siyana sema mukurapa zvinodhaka "third 400", rondedzero pakuranga unotora kutadzisa panowanikwa ganda mapundu, pruritus, sema rhinitis uye anaphylaxis.

At yakakwirira chipimo chemushonga uye kushandisa kwenguva yakareba pamusoro zvinodhaka "third 400" mirayiridzo rinonyevera pamusoro zvaipesana kuona basa,-siyana ropa (uterine, gastrointestinal, hemorrhoid), uyewo panowanikwa gastrointestinal ulceration.

Pakusarudza kurapwa kuti "third 400" zvinodhaka vanofanira kungwarira, nokuti ane nhamba contraindications:

- zvirwere zvomudumbu turakiti;

- svota siyana;

- "asipurini vanamwari vatatu vatatu";

- Children pasi makore 12;

- pamuviri uye panguva lactation;

- hypersensitivity kuti ibuprofen;

vanofanira kutarisira zvikuru apo:

- neBP;

- kukwegura;

- mwoyo kutadza;

- colitis, gastritis, enteritis;

- kukundikana - chiropa, itsvo;

- peptic urikanwi chirwere uye cirrhosis.

Female wembereko akaona kunambwa zvinodhaka, hazvina ashandise "third 400" vakadzi kuronga pamuviri.

The chipimo chemushonga zvinodhaka akatsunga nomumwe, kazhinji kusvika 200 MG pazuva nokuda vakuru, vanofanira kuwedzera kurapwa nguva zvakakodzera kubvunza nyanzvi.