"Theofedrine": murayiridzo. Mapiritsi "Theofedrine": kuongorora, mutengo

Ndinofanira kushandisa sei Teofedrine? Mirayiridzo yekushandiswa kwechiri ichi inotsanangurwa zvakadzama munyaya yakataurwa. Inoratidzawo kuti mutengo uyu unokosha zvakadini, chii chinogadziriswa, nemigumisiro ipi, yakafanana uye zvinopesana nezvayo, chii chinowanikwa mukugadzirisa, nezvimwewo.

Kuumbwa, maitiro ekugadzira, kugovera

Mutevedzeri weTofedrine inogadzirwa sei? Iro murairo wemurapi uyu unoti unobudiswa chete muhuwandu hwehwendefa. Vane muchena kana mutsvuku, pamwe chete nesimbi yakadzika-cylindrical. Pirafura imwe neimwe ine chikwata uye inclusions.

Ndeapi zvinhu zvinonzi mishonga ye "Theoferrin" inosanganisira? Kuumbwa kwechirwere ichi kwakafanana neizvi:

• Zvinhu zvinoshanda: paracetamol, theophylline, cytisine, phenobarbital, ephedrine hydrochloride, caffeine uye bladladonna yakabudiswa.
• Zvimwe zvinhu: stearic acid, mbatata starch, povidone uye calcium stearate.

Nokudaro, inogona kugadzirirwa zvakasimba kuti mishonga "Theoferrin H" inosanganiswa nemishonga.

Matafura ari kutengeswa munharaunda dzomukati, izvo zvinowanikwa mumapakiti emakadhibhodi.

Pharmacological action

Chirwere cheTeofedrine, mutengo waro wakanyorwa pasi apa, inogadziriswa mishonga. Iine antispasmodic uye bronchodilator effect. Izvi zvinopiwa kune kusanganiswa kwezvinokonzerwa nemethylxanthine (caffeine uye theophylline) ne m-cholinolytic atropine uye sympathomimetic ephedrine, iyo inonyanya kuita zvinhu zvebladladonna yakabudiswa.

Kana iri phenobarbital, inobvisa kushamiswa kwenheyo yenheyo.

Zvimwe zvemurapa

Vose bronchodilator zvinodhaka, kusanganisira mishonga "Theoferrin", zvakafanana mune zvavanoita. Izvi zvinoreva kuwedzera kubvumirana kwebronchi, kunoderedza kushandiswa mukati mechikamu chiduku chekupararira kweropa, uye kunowedzerawo midziyo yemapapu, midziyo yemakononary, inokurudzira nzvimbo yekufema, inobata chimiro chinokonzera (zvishoma nezvishoma inotumidzwa), inowedzera renal ropa inopera, simba uye mwoyo wekura.

Mumwe haakwanisi kubatsira kutaura izvozvo nekuda kwekuvapo kwezvinhu zvakadai separacetamol mukugadzirwa kwemishonga, ine an analgesic uye antipyretic effect.

Pharmacokinetics

Mushonga uyu "Theoephedrine" wakanyatsogadziriswa here? Iyo mirayiridzo inoti kana mushure mokutora mahwendefa mukati, nhengo yavo inoshandiswa inobata zvakakurumidza kubva kune gumbo rekudya.

Iyo yakanyanya kukanganiswa kwemishonga iri muropa inowanikwa mushure memaminitsi 60. Iko yakagadzirirwa metabolite yeparacetamol yakadhindwa kwemaawa mana (pamwe chete nomugini). Ihafu-hupenyu hwechirwere chisina kuchinjwa kubva plasma inenge maawa matatu. Kana itsvo uye chiropa zvinokundikana, uye kana zvikaitika kudarika, izvi zvinogona kuwedzera.

Iyo yakawanda yakakosha ye theophylline muropa inosvika anenge maawa maviri mushure mokutora mahwendefa. Hupenyu hwaro huri maawa gumi nemaviri.

Kubatanidzwa kweatropine nemaprotini eprotein kunosvika 18%. Anenge makumi mashanu kubva muzana yeiyo zvinhu zvakanyanyiswa pamwechete nemuyo.

Kana iri ephedrine, inonyatsodonhedzwa kubva pamigwagwa yekudya, inogadzira uye inochengetedza hutano hunodiwa hwechirwere muropa. Yakashandura ichi chiropa muropa, uye yakanyonganiswa pamwechete nemuviri.

Zviratidzo zvekushandiswa

Ndechipi chinangwa chemapiritsi anogona kupiwa? Teofedrine? Kazhinji kazhinji inoshandiswa sechirwere chekubatsira kune zvirwere zvepemiti yepamusoro, iyo inosangana ne bronchospasm. Uyewo, mushonga unorayirwa kuti:

• Bronchial asthma;
• Chronic bronchitis (kuvhiringidza);
• Emphysema yemapapu.

Contraindications for use

Sezvo mutemo, bronchodilators, kusanganisira mushonga we "Theoferrin", hauna kurongerwa kune varwere apo:

• Angina pectoris;
• Kutadza kwemoyo kwechimiro chisingaperi;
• Kurwisana kwekodonary circulation;
• Angle -vhavhara glaucoma;
• Kushungurudzika kwetariro yemwoyo;
• Hyperplasia of the prostate;
• Hyperthyroidism;
• Kusuruvara uye mamwe mamiriro ezvinhu anotyisa;
• Arterial hypertension;
• Kuberekwa;
• Muhuduku (chete kusvika pamakore 18);
• Pakati pekunyora;
• Hypersensitivity yemurwere kune zvikamu zvinopinda muropa.

Inofanirawo kuonekwa kuti mishonga iyi inoshandiswa nekuchenjerera zvakanyanya mukushuga kwechirwere cheshuga, kuora uye kushaya simba, kukanganisika kwekutsvaira, uye kusagadzikana kwekutengesa zvinodhaka.

Theophedrine mishonga: mirayiridzo yekushandiswa

Nhengo inofungidzirwa inotorwa nemuromo. Kuvhara kurwiswa kwechirwere chechibhakera, inoshandiswa sevatsigiri. Mushonga wacho unotorwa kamwe chete pamapiritsi maviri pazuva. Kana zvichidikanwa, mumiriri anogona kunyoreswa 2-3 nguva pazuva. Dhigirii yepamusoro yezuva nezuva mapiritsi matatu.

Pamusoro peprophylaxis, mishonga inotorwa nemuromo kana hafu yeplateti yose mushure mekudya (kamwe pazuva).

Kuti urege kunetseka kwekurara kweusiku, mushonga unotorwa mangwanani kana masikati.

Nguva yekurapa nemishonga yakadaro inobva pane zvakasikwa, pamwe chete nehutano hwechirwere uye chiitiko.

Zviitiko zvakashata

Kukanganisa kwakashata mushure mokutora mishonga mumubvunzo kunoitika zvisingaiti. Zvisinei, pane dzimwe nguva, murwere anogona kuona zvinotevera:

• Mwoyo rhythm kuvhiringidzika uye tachycardia.
• Kushushikana mupfungwa, kuora musoro, kudengenyeka, kusuruvara, kukanganiswa kwehope.
• Nausea, kuderedza chido, kurutsa, kuchema mwoyo.
• Dry mouth, urinary restoring, sweeping sweating, reaction allergic.

Overdose

Kana zvisina kutorwa mahwendefa (muzinga repamusoro), anogona kukonzera zviratidzo zvinotevera zvehupfu hunotyisa: kurwadziwa kwepamuviri, kushungurudza, kuora mwoyo, kusuruvara, kuonekwa kwemaonero, kusuruvara.

Inofanirawo kuonekwa kuti ephedrine, inotorwa nehana yakakwirira, inonyatsoita kuti kuwedzerwa glucose muropa. Lethal letsi (nemuromo wekutonga) inosara 1 g.

Kana iri paracetamol kudarika, munyaya iyi murwere anogona kukura hepatonecrosis, kuwedzera prothrombin nguva, uye kuwedzera basa rechiropa transaminases. Izvozvo zvinowanzoitika mushure mokutora zvinopfuura 10-15 g yezvinhu zvakataurwa.

Sokurapa kwekudarika, gastric rinopisa, kushambidzika kwekuita uye zvirwere zvinoratidzira zvinoshandiswa.

Kubatana Kwemishonga

• Beta-adrenoblockers, carbamazepine, asinganzwisisiki anticoagulants, furosemide, cimetidine, antibiotics, verapamil, fluoroquinolones, MAO inhibitors, GCS uye mishonga yekudzivirira mishonga inokwanisa kuwedzera kuwanda kwe theophylline muropa uye kuwedzera njodzi yekuita zvakaipa.
• Kubvisa krasavki kunowedzera simba re anticholinesterase mishonga uye m-holinomimetikov.
• Paracetamol inowedzera dzimba dzeanticoagulants. Hepatotoxic effect yeparacetamol inowedzera nekushandisa kumwechete kwe phenytoin, barbiturates, rifampicin, carbamazepine uye zidovudine.
• Nekushandiswa kwakabatana kwe ephedrine ne MAO inhibitors, matambudziko akakomba anonyanya kuitika anoitika. Inofanirawo kucherechedza kuti ephedrine inokanganisa nzvimbo dzeanpioid analgesics nemimwe mishonga inoodza mwoyo chirwere chetsitsi.
• Nechishandiswa panguva imwechete ye bronchodilator nevasiri-selective beta-blockers, zvinoitika zvekare zvakashata.

Theophoodrin mishonga: analogues uye mari

Nekushandiswa kusingashandisi kwechirwere "Teofedrine" vanachiremba vanoratidzira zvakafanana zvechirwere ichi. Iyo inobudirira zvikuru uye inozivikanwa ndiyo mishonga inotevera: Bronchophillin, T-Fedrin uye Trifedrine IC.

Zvirongwa zvakarongedzwa zvine zvinyorwa zvavo, maererano nezvinofanira kushandiswa chete mushure mekugadzwa kwechiremba.

Ndezvipi mahwendefa eTofedrine? Mutengo wemishonga iyi haisi yakakwirira. Yaro inodhura yakawanda ndeyeRussia rubles. Munyaya iyi, inofanira kutarisirwa mupfungwa kuti zvakaoma kutenga mishonga yakadai mumaparammita. Icho chinowanzosunungurwa, uye ndicho chikonzero icho chinowanzosimbiswa neiripo yakafanana.

Kuongorora nezvechirwere

Vakawanda vevarwere vakambotora dhirairi iyi vanoti inoshanda zvikuru. Zvisinei, vamwe vanhu vanogunun'una kuti vanachiremba vanopa kwavari mishonga yakadaro yakanyanyisa nekutya kukuru.

Inofanirawo kuonekwa kuti kune zvakawanda zvakataurwa nemishonga iyo inogona kukonzera kugadzikana kwepfungwa. Panyaya iyi, kugamuchirwa kwake kunofanira kunge kwakanyatsodzorwa nachiremba.