Vasodilator madhiragi.

Vasodilator madhiragi mishonga ine musuru inononoka simba pamasvingo emidziyo, sechikonzero chekuti chiedza chemidziyo chinowedzera. Iboka iri remishonga rinoshandiswa kunyanya se antihypertensive uye analgesic (relieves spasm) therapy.

Vasodilator zvinodhaka zvinogona kunge zvakagadzikana kuva beta-adrenoblockers, nitrates uye inhibitors yeACE receptors.

Iyo nzira yekuita kweB-adrenoblockers yakaderedzwa kusvika pakuvharwa kweperiipheral receptors yemutsipa wemwoyo kubvira pane zvakaitwa nema catecholamines. Izvo zvinewo zvigadziro zvinoderedza kuwanda kwepfungwa paminiti, zvichiguma nekuderera kwechibereko chemoyo. Kudzivirirwa kwemhirizhonga yemapapiro kunotungamirira kuderera kwemyocardial oksijeni yekushandisa uye kuderera kweropa.

Beta-adrenoblockers vane simba rinopesana, pamwe chete nekudzivisa basa rehaini mu plasma yeropa. Iri boka rezvinodhaka rinewo chirwere chemhepo, i.e. Inobatsira kudzorera myocardiocytes. Beta-adrenoblockers yakakamurwa kuva sarudzo uye isingasarudze (pamwe uye pasina muitiro we sympathomimetic).

Vamiririri vanokosha:

1. Propranolol naNadolol (pasina basa remukati remukati sympathomimetic).
2. Pindolol naOxprenolol (pamwe nekuvapo kwemukati basa).
3. Bisoprolol, Betoxolol, Atenolol (kusarudza).

Kune huwandu hwezvirwere umo kushandiswa kwe beta-blockers kunoratidzwa:

- IHD, angina pectoris;

- Arterial hypertension, dambudziko;

- rhythm mhirizhonga (tachycardia);

- moyo kusakwanisa;

- Myocardial infarction munhoroondo;

- Migraine.

Pane humwe hutano mukugadzwa kwe beta-adrenoblockers mukudzivirira, chirwere cheshuga uye lactation, asi izvi hazvirevi kuti zvinopesana nemamiriro aya. Zvinyorwa zvisinganzwisisiki nezvekugadzwa kwezvinodhaka izvi ndezvi:

- chronic obstructive pulmonary pathology;

- purogiramu vascular disease;

- kudzivirirwa kwemwoyo 2-3 digiri.

Zvimwe zvinokonzerwa nekugadza vadzidzisi:

- Zvinetso zveV Vascular nenzira yekushaya simba kana kutonhorera kumativi, kupera kwebronchi huru.

- kutyora ropa ropa (kuwedzera muropa glucose, kuonekwa kweurea).

Izvo vasodilator maitiro e nitrate boka rimwe remishonga inotanga kushandiswa kurapa huwandu hwehutano, myocardial ischemia, matambudziko. Iyo nzira yezvavanoita ndeyokuderedza kusvuta kwomweya mukati myocardium, somugumisiro wekuti mishonga dzomumativi dzinowedzera uye kudzoka kwehupenzi kweropa kuderera. Iyi mishonga inoita kuti kuwedzerwa ropa rinowedzera nekuda kwevasodilation, uye, nokudaro, kubvisa marwadzo emakironi emakoroni.

Vasodilator Kugadzirira kwe nitroglycerin yakatevedzana hakugoni kushandiswa muhupo hwehutachiona humorrhages uye kuwedzera kusagadzikana, Mumamiriro ezvinhu aya vanongowedzera kuoma kwechirwere.

Vasodilator mishonga yemusoro inoshandiswa kunyanya kune migraines uye kupararira kwemidzi yeropa. Mumamiriro ezvinhu akadaro, zvakanakisisa kushandiswa neboka re beta-adrenoblockers, vane chirevo chekutaura myorelaxing pamadziro emidziyo yeropa

Gwaro rekupedzisira remishonga - vasodilator zvinodhaka, izvo zviri zvekirasi yeACE inhibitors. Zvinhu izvi zvinoshandiswa kunyanya nehuwandu hwemyocardial infarction, hutachiona hwehutachiona, hwakasiya kusimba kwechiremera chemoyo. Kupindirana kwekusarudzwa kwavo kune pamuviri, hyperkalemia, stenosis yemakumbo emarara.

Iyo nzira yekuita kwemishonga iyi ndeyo kuratidzwa kwehutachiona hunokonzerwa neurohumoral (yakawedzerwa kallikrein-kinin system, kuwedzerwa kwemugumo we endothelium-kuremara chinokonzera) nemigumisiro yemagetsi (antioxidant effect, yakawedzera potasium yezinga, kuwedzerwa kunzwisiswa kwehutachiviri hwemashutu).

Mishonga yevasodilatation inowanzoshandiswa mukurapa kwemazuva ano uye ine maitiro akanaka ekurapa muzvirwere zvemidziyo yemusoro nemwoyo, uye pamwe nekuvapo kwechinangwa chisingaiti mumoyo medu.