A bvunzo ropa antibodies panguva pamuviri: kunyanya kudzidzisa, decoding uye vanorumbidza

Achironga pamuviri - chinokosha uye yakaoma kuti inoda marudzi ose kuongorora, kuti yekuzvidzivirira zvirwere panguva nepamuviri uye pakusununguka. miedzo ropa antibodies mu pamuviri - inzira chirwere. pamuviri asati kunokosha kuona pamberi antibodies kuti rubella utachiona uye vamwe tochi-zvirwere, kuti kutaridzwa ropa boka uye kusapindirana kweropa chinokonzera pamusoro kuwanana. Zvinobuda achasarudza kudiwa zviyero zvainanga inowanzotorwa kukura kwemwana.

Antibodies kuna tochi-zvirwere

Ichi boka zvirwere zvinosanganisira:

• rubella;
• cytomegalovirus;
• herpes chirwere;
• toxoplasmosis.

Zvirwere izvi zvinonyanya ngozi panguva gestation mwana. Chirwere mumwe mukadzi wokutanga trimester kunotungamirira pakupona, malformations uye vaingoerekana pamuviri. Nyanzvi vanokurudzira miedzo nokuda antibodies ari pamuviri ropa muvhiki 12 dzokutanga, uye nani vachiri kuronga nguva.

Chirwere pamwe herpes simplex kunogona kukonzera polyhydramnios, chidzivaidzo pamuviri, zvinoguma nokupfupfudzika, pave intrauterine noutachiona, Prematurity. Kana mukadzi ari utachiwana kokutanga, njodzi kuti utachiona zvichaitika mwana rinosvika 50%.

HweHIV toxoplasmosis chinonyanya ngozi kuti mwana ari wechitatu trimester. Kana mai achirwara ari wokutanga uye chechipiri, ngozi nehosha iri mwana kunosvika 25%, nomwedzi wechitatu - 90%. Chirwere pamwe rubella panguva yokutanga 4 months fetus upenyu inotungamirira pokufa mudumbu, kukura makro kana microcephaly, chitarisiko vanamwari vatatu vatatu Gregg.

Cytomegalovirus ndiyo ngozi uropi mwana, kukura palsy, kunzwa abnormalities uye kutarisana analyzer.

A muedzo antibodies ari pamuviri ropa quantified zviratidzi ose immunoglobulins G uye M. Ndiwo inokosha chirwere zvinodiwa.

inopangidza

Panguva mukubereka vana migumisiro kudzidza anogona kuva muchimiro zvinotevera nzira:

1. IgG uye IgM vakanga dzakaonekwa. Izvi zvinoreva kuti amai ndamboonana pamwe nezvirwere zvakadai, izvo zvinoreva kuti chirwere unogona kuitika panguva gestation mwana. Studies inodzokororwa mwedzi wose.
2. IgG uye IgM kwakawanikwa. Mugumisiro anotaura pamusoro nyaya ichangobva zvokutapukirwa. Zvakakosha kuita wokuwedzera muedzo antibody titers ropa panguva yepamuviri.
3. IgG ari kuona, IgM haina dzakaonekwa. Uyu yakanaka chingaitwa mai nomwana. Rinodaro refu-utachiona.
4. IgG haina kuona, IgM dzakaonekwa. Uchapupu achangopfuura noutachiona uye kunoda mamwe chirwere dzokuvhiya.

Dudziro migumisiro kumbova chiremba-rabhoritari mubatsiri, uye chiremba uyo anotaurwa kumukadzi ongororo. Pachishandiswa zviratidzo rinotsanangurwa mberi Zano pamuviri.

alloantibody

Izvi mhando antibody kunoitika apo kusapindirana kweropa-kupesana mai nomwana. Kusapindirana kweropa chinhu - chaiyo antigen anogona kuva pamusoro erythrocytes dzevanhu. Kana ariko, saka ropa anonzi kusapindirana kweropa-akanaka, kusavapo - kusapindirana kweropa negative.

Kana mukadzi asina kusapindirana kweropa chinhu, uye mwana vakagamuchira nhaka yake baba vake, amai anotora mwana kusapindirana kweropa kuva muviri wokumwe uye inobereka antibodies pamusoro matsvuku masero mwana. Panguva yokutanga pamuviri, izvi zviri ichangotanga, uye kazhinji haana kunotoreva migumisiro, asi chinoratidza pacharo zvikuru rinopikisa munguva tevera gestation. Saka dzichiri Rhesus-kunetsana.

The chikuru Kupindura muviri raamai anoratidza chizvarwa IgM. Vane yakakwirira samolecular uremu uye, naizvozvo, haagoni kupinda kuburikidza placental chipingamupinyi. Secondary sensitization kunoitika muchimiro generating inokosha mari yakaderera samolecular uremu IgG, izvo zvinogona kupinda mukati muviri azvarwa.

Kuongorora chirwere Rhesus kunetsana

Analysis ropa rhesus antibodies ari pamuviri ane zvinotevera zviri:

1. Kana vakaroorana kusapindirana kweropa negative, nechirwere hakusi zvakakodzera kuita.
2. Kana amai kusapindirana kweropa negative uye baba kusapindirana kweropa positive ropa, vakatsunga titer pakati kusapindirana kweropa antibodies ikaitika mune simba rose pamuviri (pamwedzi).
3. Kuziva yapfuura antibody titers achasarudza pamberi sensitization.
4. IgM havasi ngozi nokuda mwana, uye kuvapo IgG rinoti tinofanira kujekesa zviratidzi titer uye kuramba pedyo richiona akazvitakura.

Njodzi zvinhu uye zvichiita yematambudziko

Pangozi yokuva kusapindirana kweropa-kunetsana zvinosanganisira vakadzi vane nhoroondo anonyengetedzwa pamuviri kwakacherechedzwa mukupera pamuviri, kuwedzerwa ropa, setsika zvinoguma nokupfupfudzika, kuvapo kanganisika kuzvarwa uye ectopic pamuviri.

Somugumisiro zvikuru makakatanwa hwapedyo hemolytic chirwere pamusoro achangoberekwa, izvo pamwe anotevera matambudziko:

• nokuberekwa akafa mwana;
• encephalopathy;
• hypertrophy kuti chiropa uye chirwatata;
• kernicterus;
• Muzvarirwo kunonoka kukura;
• hepatic insufficiency.

Pane matanho kukura kusapindirana kweropa-kunetsana. Pasina Rhesus mukadzi panguva yake yokutanga yepamuviri raitongwa Anti-D gamma globulin. miedzo ropa antibodies ari pamuviri rinoitwa nechimwe anotevedzana pechiitiko kubereka, kuziva titer kuti zviratidzo. Norm haatarisiri mamwe jekiseni gamma globulin pa dzakakwirira rates, izvozvo chinotarisirwa nenzira chaiyo muenzaniso vakawanda nguva.

Group antibodies

vanhu vashoma vanoziva kuti dambudziko ingasava musiyano chete ndiye kusapindirana kweropa chinhu, asi mapoka akasiyana kwevarume ropa. Group kunetsana kuri kushoma zvechisimba kurutivi mwana pane kusawirirana kweropa raamai neremwana. Matanho kudzivirira kukura zvakadaro haako.

Analysis boka ropa antibodies panguva pamuviri mutemo unoti zvinotevera nyaya:

• kusvodza;
• pathological wakurukura munhau;
• nekukudziridza placental abruption munguva yapfuura pamuviri uye kuzvarwa;
• ropa;
• pamuviri kare.

antiphospholipid antibodies

Phospholipids inonzi mafuta anoumba membranes nemasero pamuviri. Vakazvimiririra kubudisa vanhu avo asingagoni, asi pasina kwavari, zvakare. Izvi zvinhu tiri STRUCTURAL zvinhu, inobatanidzwa pakugwamba ropa, akaderedza dzaparadzwa sero masvingo, kutsigira tsinga.

Kana antiphospholipid antibodies nepamuviri pane kuparadzwa mafuta uye kukura kwakaita antiphospholipid syndrome. Primary chirwere ndiye asymptomatic, muviri nokukurumidza ipfupi. The yechipiri zvikuru nehasha uye hwakazara kukura thrombosis. Izvi zvinowedzera mukana yomwoyo, embolism, sitiroko, maronda rwengarava zvikuru.

Nokuti vakadzi vane pamuviri vanova APS achabatsirwa refu ngozi:

• kupfupfudzika;
• kubereka mwana akafa;
• Fetal hypoxia;
• vachiberekwa anomalies;
• vakurumidze yokuzviparadzanisa of placenta.

Diagnostics Features

A muedzo antibodies panguva pamuviri ropa, decoding inoitwa nachiremba, vaitungamirira mukadzi anonzi fanira zvinotevera nyaya:

• ziendamberi kusvodza;
• Kuvapo zvirwere kumwoyo;
• Kugara nomusoro;
• thrombocytopenia;
• kuvapo renal kana hepatic chirwere.

Ropa zvakaitika kutsunga antibodies kuti cardiolipin zviratidzo uye phosphatidylserine. Chinokosha rakawanda antibodies haisi wakananga simbiso APS. Chiremba inorangarira nokupenya zvekuchipatara zviratidzo uye kurapwa nhoroondo Data. High titer inoratidza kudiwa kugadzwa antiplatelet nevasori (zvinodhaka kuti hwamunoita dzinotsanagura thrombosis).

Sei bvunzo ropa antibodies panguva pamuviri

Kune chirwere zvabuda dzakanga dzakarurama, zvakakodzera kugadzirira fenzi zvinhu. Mazuva 2-3 rambai zvinwiwa zvine caffeine, pasoda, Spicy zvakakangwa, pickled zvokudya,. Pass kuongororwa kuti antibodies ropa panguva yepamuviri usina chawadya.

Kana zvichibvira, kurega kunwa mushonga. Kana zvisingaiti, zvapinda yezvirwere, zvinoreva chii anoshandiswa. Hyperthermia uye nguva pashure yakawanda mumuviri nesimba vari contraindications kuitisa Diagnostics.

Pashure pokugamuchira migumisiro decoding kwave obstetrician-gayinakorojisiti ane pamuviri. Tinyatsonzwisisa zviratidzi anosarudza kudiwa kugadzwa zvokuwedzera uye kururamiswa. Chero unprofessional nokuzvidzora kududzirwa zvabuda haabvumirwi, nokuti hungada upenyu amai mwana.