"Amlodipine": chii chinobatsira, mirayiridzo yekushandisa, mifananidzo, maitiro

Chii chinonzi hypertension? Vanhu vazhinji vanoziva mhinduro kumubvunzo uyu, kunyanya vakwegura. Sezvaunoziva, uku ndiko kuwedzera kuwedzerwa kweropa, iyo inoratidza zviratidzo zvakadaro se 150/90 mm Hg. Art. Uye kumusoro.

Zvinowanzofungidzirwa kuti hypertension ndiyo inowanzosangana nehosha yehutano hwemwoyo. Kuwedzera kwekuwedzera kweropa kunowanikwa muna 25-30% yevanhu vakuru. Nenzira, nezera, chirwere ichi chinoonekwa muna 55-65% yevanhu.

Chii chinoita kuti artertension iwedzere? Izvi zvinogona kuitika nekuda kwezvikonzero zvakasiyana-siyana. Kazhinji kacho kune vakwegura vanhu vanomanikidzwa kunokonzerwa nekufunga kwepfungwa-mupfungwa. Nokudaro, vanhu vanotarisana nehutachiona vanofanira kunge vakanyarara sezvinobvira.

Mumwe haakwanisi asi anotaura kuti chirwere chakadaro chinowanzobva pamararamiro ekugara, makore, zvepabonde (kanowanzova vamiririri vehafu isina simba yevanhu), kunyanya kushandiswa kwetafura yemunyu, hypocalcemia kudya, kunwa doro zvisina kufanira, hutano, hupenzi, kusvuta, chirwere cheshuga uye Etc.

Izvo zvakakosha here kubata chirwere chepfungwa chepamusoro? Vanachiremba vanotaura kuti kana iwe uchinzwa usina kufara, murwere anofanira kunyatsotora zvinodhaka kuti ropa rezasi risanyanya. Kune mumwe wavo anotakura mishonga yakadaro se "Amlodipine". Zvivhiringidza zvechirongwa ichi, zvikamu zvayo, mari uye zvakafanana zvinoratidzwa pasi apa.

Tsanangudzo yemishonga, chimiro chayo uye kugovera

Mune mhando ipi mishonga "Amlodipine" inogadzirwa, mutengo waro unoratidzwa pasi apa? Chirwere ichi mubvunzo chinobudiswa mumhando yemapiritsi machena uye fomu-flat-cylindrical. Chinhu chacho chinoshandiswa chinonzi amlodipine.

Iyi mishonga inotengeswa mumiganhu yepiritsi (mapiritsi gumi), ayo akaiswa mumakadhibhodhi emapuraneti.

Iyo nzira yekuita kwechirwere

Chii chakanaka pamusoro peAmlodipine? Maererano nemirayiridzo, ichi chirwere chinoratidza kuratidzira antihypertensive uye antianginal properties. Mukuwedzera, haibvumiri calcium ions kupinda mukati memumakumbo muvascular cells uye myocardial cells.

Chii chinonzi "Amlodipine"? Chii chinobatsira mishonga iyi? Izvi zvinoderedza zvakanaka kukonzerwa kweropa. Izvi zvinokonzerwa nekukwanisa kwemishonga yekuderedza midziyo yeropa.

Inofanira kuonekwa zvakare kuti mushonga uri mubvunzo une antiininal effect. Iyi chivako chemishonga inopiwa nechikamu chayo chinoshanda. Vanachiremba vanoparidza kuti amlodipine haisi kungotsanangurira arterioles (paripheral), asi inoderedzawo OPSS. Muchiitiko ichi, izvo zvinoshandiswa hazviiti kuti tachycardia (reflex).

Ndeipi mugumisiro wekushandisa mushonga we "Amlodipine"? Chii chinobatsira chirongwa ichi? Kuvonga nekugadzirira kwakadaro, moyo wemunhu unotanga kudya zvishoma simba uye chido chemuyocardium mu okisijeni chinoderera zvikuru.

Kinetic zvikamu zvechirwere

Mushonga we "Amlodipine" kubva mukudzvinyirira (kuwedzerwa) unobviswa kubva mumutsipa zvishoma nezvishoma, asi zvakakwana. Nhamba yepamusoro yekutora kwayo inoshanda muropa inosvika mushure memaawa 8.5. Kusungirirwa kwechirwere ichi kune plasma mapuroteni inenge 98%.

Mushonga we "Amlodipine", uyo ane chinangwa chekuderedza kushungurudzika, kunotapukisa kusanyanya kwemasabolism. Muchiitiko ichi, zvigadzirwa zvinoumbwa zvinenge zvisingabatanidzi zvemishonga. Mushonga wacho unoshandiswa mumagetsi kana uchipfuura nepachiropa.

Ivhareji yehafu yeupenyu ye amlodipine uye yakagadzirwa nayo maawa 36. Nehuwandu hwekuwedzera kweropa, nguva ino inogona kuwedzerwa kusvika mumazuva maviri, kune vanhu vakwegura - kusvika maawa 66, uye nechiropa chisingaiti - kusvika maawa makumi mashanu.

Chirwere chinoshandiswa nenzira ye metabolites kuburikidza nemukumbo uye itsvo.

Mushonga we "Amlodipine": chii chinobatsira?

Muzviitiko zvipi mishonga inogona kurairwa kumurwere? Zviratidzo zvekutora mushonga uyu ndezvipi zvinotevera:

• Stenocardia yakasimba;
• Vasoconstriction kana vasospasm;
• Angina pectoris;
• Hypertension arterial (se monotherapy uye pamwe chete nemimwe mishonga);
• Cardiomyopathy dilated non-ischemic.

Ndezvipi zvimwe zviitiko zvinogona kugadzirwa nemishonga "Amlodipine"? Chii chinobatsira mishonga iyi? Inowanzonyorerwa pamwe chete nemishonga inorwisa antianginal, kusanganisira varwere vasina kurwara nemishonga ne beta-blockers kana nitrates.

Zvinorambidza kutora mushonga

Iye zvino unoziva, nokuda kweizvi varwere vanorayirwa mahwendefa "Amlodipine". Zviratidzo zvemishonga iyi zvakanyorwa pamusoro apa.

Kana zviri izvo zvinopesana, kushandiswa kwemishonga iyi kunorambidzwa nehutano hypotension. Mukuwedzera, hazvikurudzirwi kushandiswa pazera duku, pamwe nekuvapo kwe hypersensitivity kune zvigadzirwa.

Ndinofanira kutora sei Amlodipine?

Nhoroondo, mutengo wemushonga uyu unoratidzwa pasi apa.

Mushandi wacho anogadzirirwa kunyora mumuromo. Muyero wechiremba uyu unoratidzwa nachiremba, zvichienderana nemamiriro emurwere.

Kune varwere vane hypertension (arterial) uye angina pectoris, chirwere chiduku chemishonga zuva nezuva 5 mg. Kana zvichidiwa, panguva inotevera chiyero ichi chinogona kuwedzerwa kaviri, kureva, kuunza 10 mg pazuva.

Mukurapa kwekadhirodiyo chirwere, chirwere ichi chinokurudzirwa kutora mumuviri we 2.5 mg. Kana mushonga wacho wakanyatsotsungirira, huwandu hwahwo hunogona kuwedzera kane.

Maererano nedzimwe nyanzvi, huwandu hunorayirwa huwandu hwemishonga (inopfuura 10 mg pazuva) hunoodzwa mwoyo, sezvo izvi zvinogona kutungamirira mukuvandudzwa kwemigumisiro isina kunaka.

Kugamuchirwa kwe "Amlodipine" pamwe ne beta-blockers, diuretics (thiazide) uye ACE inhibitors hairevi kuchinjwa kweiyo.

Zvikanganiso

Ndeipi mushonga we "Amlodipine" wakatakurwa nevarwere? Zvimwe zvinokonzerwa neizvi zvinodhaka zvinenge zvisipo. Zvisinei, mune zvimwe zviitiko (somuenzaniso, kana zvisina kukodzera nematare), zvinogona kukonzera:

• Tachycardia, gingival hyperplasia, hyperemia, kugona;
• Arrhythmia, nausea, palpitation, musoro, dyspnea;
• Urombo hwepamuviri, peripheral edema, kuneta;
• Arterial hypotension, rash, paresthesia, itching, chizuru.

Inofanirawo kuonekwa kuti nekushandisa kwenguva yakawanda mahwendefa ari mubvunzo, murwere anogona kunzwa kurwadziwa mumakumbo.

Mhosva yekuderedza zvinodhaka

Mashoko pamusoro pezviitiko zvekuwedzeredza nemishonga iyi haisipo nhasi. Kunyange zvazvo vanachiremba vachiratidza kuti kana kutora huwandu hwechirwere muvarwere kunogona kuratidza zvakakomba migumisiro.

Kubatana Kwemishonga

Inobvumirwa here kutora mishonga yeAmlodipine pamwe nemamwe madhiragi? Mirayiridzo, kuongororwa kwezvenyanzvi kunopikisa kuti kushaya hypotensive kwechirwere ichi kunosimbiswa kana ichibatanidzwa ne calcium channel blockers. Chiitiko chakafanana chinotarisirwa kana uchishandisa mari inotarisirwa kuti inhalation anesthesia ne orlistat. Nenzira, kushamwaridzana kwakadaro kunogona kukanganisa kunyange dambudziko rehutachiona.

Kuderedza kushaya simba uye kusachengetedza kwemuviri mumutumbi wemunhu kunoonekwa nekushandiswa kwemapiritsi "Amlodimin" ne estrogens uye sympathomimetics.

Kubudirira kwezviratidzo zvakadai zveurourotoxicity seminnitus, nausea, ataxia, kurutsira uye chirwere chinokonzerwa nehurumende panguva imwechete yeamlodipine uye lithium carbonate.

Kushandiswa kwechirwere chechirwere ichi mubvunzo uye indomethacin, pamwe chete nedzimwe NSAID, zvinotungamirira kuderedza kuderedzwa kwehupenyu hwekare.

Kuyamwisa uye pamuviri

Kuchengetedzwa kwechirwere "Amlodipine" panguva yekuzvitakura hakuna kumbobvunzwa. Izvo zvinoshandawo kumararamiro emakore. Munyaya iyi, mishonga iri mumiganhu yakadaro inofanira kushandiswa chete kana ngozi kune mwana isinganyanyi kukosha kune utano hweamai.

Zvose zvinorayirwa nezvekutora mishonga

Iyo mirayiridzo, yakabatanidzwa pamahwendefa, inotaura kuti inofanira kutorwa nokuchenjerera zvakanyanya kana isina chiropa chakakosha uye basa repvo, pamwe ne stenosis ye aortic aorta.

Kugadziriswa kwemuti wezvinodhaka, izvo zvakataurwa pamusoro, hazvidiwi kune vanhu vakwegura.

Mishonga "Amlodipine" inogona kushandiswa kurapa varwere vane chirwere chakadai se dilate cardiomyopathy (kwete-ischemic), iyo inofambidzana nemoyo kusagadzikana (kusingaperi).

Zvidzidzo zvekliniki nezvekushandiswa kwechirwere ichi mubvunzo mukurapa kwevana hazvina kuitwa.

Mitemo yekutsvaga nekuchengetedza, nguva yekushandiswa

Chengetedza mishonga iyi munzvimbo ine rima uye yakaoma, umo kutonhorera kwepanyika hakupfuuri madigiri makumi maviri, uye apo vana vaduku havagone kuwana.

Iyi mhinduro inosunungurwa pasina mushonga wezvokurapa. Maererano nemirairo, zuva rekupera kwemazuva makumi maviri nemana. Mushure menguva iyi, tora mishonga inorambidzwa.

Mari inoshandiswa mumishonga muma Pharmacy uye zvivako zvakafanana

Iko mahwendefa akawanda sei "Amlodipine"? Mutengo wechirwere uyu unogona kunge wakasiyana, asi chero zvakadaro hausi wepamusoro. Mushonga uri muyero ye 10 mg inodhura anenge makumi mashanu nemakumi mashanu emabhiriki, uye mumutengo we 5 mg - anenge makumi matatu nemakumi matatu.

Sezvataurwa pamusoro apa, arterial hypertension chirwere chinowanzojairika. Nokudaro, gore roga roga, makambani ekumishonga anobudisa zvinodhaka zvinowedzera kugadzirisa kukwirira kweropa. Nenzira, kune dzakawanda zvakafananidzirwa nenzira dziri pasi pekufungisisa. Vanachiremba vanotaura kuti ma antihypertensive properties anozivikanwa pamishonga inotevera: Agen, Tenox, Akridipin, Stamlo M, Adipin, Stamlo, Amlo, Normodipin, Amlodipine Sandoz, Omelar Cardio, Vero Amlodipine, Norvasc, Amlodipine Teva, Cordy Cor, Amlodak, Norvadin, Amlovas, Corvadil, Amlodigamma, Cardilopin, Amlodipine Alkaloid, Karmagip, Amlodil, Calchek, Amlodipine Zentiva, Amlonorm, Amlodipine-Agio, Amlotop, Amlodipine Cardio, Amlosus, Amlodipharm, Amlodipine Bezilat, Amlong, Am Lockard-Sanovel ", nezvimwe zvakadaro.

Mishumo yevarwere uye vanachiremba

Nezera, nhamba inowedzera yevanhu inoratidzwa nechirwere chakadai sehutachiona. Sezvazvinozivikanwa, zviratidzo zvinotevera zvinowanzoitika kune chimwe chinhu chakadai: kuve nechezuru, kuneta zvakanyanya, kuora musoro, kushaya simba, kusviba mumaziso, kubata nekudaro. Maererano nedzimwe nyanzvi, zviratidzo izvi zvose zvinopera mukati maawa mashomanana mushure mekushandisa tablet "Amlodipine" mumutengo we 5 kana 10 mg.

Vanachiremba vanoparidza kuti mushonga uri mubvunzo ndeimwe yenzira dzinokurumidza uye dzinoshanda zvikuru. Mukati penguva pfupi, inogadzirisa chirwere chemurwere, uye inonyanya kusimbisa mamiriro ake ezvinhu.

Kana vari vatengi, pakati pezvakakodzera zvechigadziriswa ichi, vanocherechedza nzira yazvo yekushandiswa uye fomu. Kuti kuderedze kuwedzera kwekumanikidzwa, murwere anodikanwa kutora bheti rimwe chete. Muchiitiko ichi, vanachiremba vanonyevera kuti kudarika kwechirapa uyu kunogona kuita kuti kuve nekuwedzera kana kuwedzerwa kwemashoko akashata. Munyaya iyi, havakurudzi kudya anodarika 10 mg yemishonga zuva nezuva.

Zvinofanirawo kuonekwa kuti nhamba huru yevatengi inofara nemutengo wakaderera wezvakataurwa, pamwe chete nekuwanika kwayo mumasipamita ose uye kukwanisa kuzvitsiva nemifananidzo.