Berlioz Disease: zvose pachena chikonzero, description, uye kunyanya kurapwa

Berlioz nehosha - ane zvirwere pachishandiswa zvipembenene ikaruma, kunyanya nezvikwekwe. It kunokonzerwa utachiona yacho genus Borrelia, uye zvichienderana kondinendi zvavanofunga zvingasiyana.

kudzidza

Zvinyorwa chirwere ichi chokutanga akazviratidza muna 1975 muUnited States. Nyaya yokutanga rakanyoreswa mutaundi duku Lyme, muna Connecticut. Saka zita. Chikonzero chidzidzo chaiva chikumbiro kuna CDC (Center for Disease Control) Vabereki vane vana chirwere "juvenile dzinonzi rheumatoid arthritis" (JRA). Zvakazova pachena kuti zviratidzo zvakafanana vane akawanda mukuru. Saka, Sezvineiwo, Berlioz (chirwere cheLyme) akanga dzakaonekwa.

exciter

A mutakuri nayo utachiona chirwere wehurumende ari gupa pamusoro genus Ixodes. Utachiona uhwu vararame uye kubereka kuti genus Borrelia spirochetes. Kana jekiseni kupinda munhu muviri mushure zvipembenene nokuruma vakawaridza kuburikidza muropa uye zvakaitika ropa-uropi mhinganidzo, achipinda cerebrospinal mvura uye kukonzera chetsinga zviratidzo.

genus uku mites kurarama kwose kwose. Kunyanya kazhinji richiwanika munyika Northern Hemisphere. Asi pano maonero ake dzingasiyana, zvichienderana kondinendi uye zvenyika.

kupatsanura

Pane unhu akawanda izvo kuona chimiro uye mhando kunotoda kurapwa mukurwara. Nokuti mumwe nomumwe wavo pane runoenzanirana branching.

• Forms: Isimba rakadini rinogona kubudiswa (Isimba rakadini rinogona kubudiswa); pachena (kuvhura).
• For: unopinza; subacute; refu.
• Chiratidzo: bezeritemnaya; erythema.
• Munzvimbo iyi: tsinga, ganda, majoini.
• Process nekuomarara: munyoro, mwero, yakanyanya.
• Chirwere: seronegative; seropositive.

Mumwe nomumwe zvinhu izvi kunoratidzwa muna chiremba chirwere uye zvinoratidzwa kurapwa uye kosi yacho chirwere. Naizvozvo, zvakakosha kusarudza zvatinofanira kuita kuti vakwanise kusarudza zvakarurama mazano.

etiology

chirwere Berlioz iri kukonzerwa utachiona of genus spirochete - Borrelia burgdorferi. Izvi giremu negative microorganism rine flagella. Inokura zvakanaka emura vezvenhau vane kunzwisisa mapuroteni sezvamunoita. In chimiro afanane munhu yakazvimoneredza zononoka kuti rotates nezvishoma. On kwayo pamusoro bacteria vane maantigen kuti vaone specificity yavo pakati subpopulations, uye anopa compartmentalized masoja mhinduro.

Rave dzinounzwa gumi nevaviri dzakasiyana pamusoro microorganism ichi, izvo zvinowanika pamakona ose apasi. Akaora, zvave vakaratidza kuti Borrelia serotype akazvimirira kunotoda mufananidzo chirwere. Saka, pasi chirwere cheLyme hazvirevi chirwere chete, asi boka rose zvakafanana, asi zvakasiyana mu nosology etiology.

pathogenetic mufananidzo

Pashure imwe gupa nokuruma, izvozvo anosuwa nemate kupinda kweropa maitiro, uye nzvimbo hwokupinda akatsvuka hunoratidzika rin'i ine Blurred yomukati pamupendero uye yokunze zvakajeka. The causative mumiririri rinoitwa nevanhu muropa yose muviri, dzimwe nyika nhengo uye munyama, chinopinda kupinda node uye musana mvura.

The rokuzvidzivirira anotanga vanoshingaira kupindura kupindira, nokutuma munzvimbo zvakakanganisa kumativi anogumbura masero (macrophages, neutrophils), uchibereka cytokines, leukotrienes, prostaglandins uye immunoglobulin makirasi M uye G. Borrelia kufa, asi manyowa kusunungurwa muchetura izvo kukanganisa muviri womunhu. Mukuwedzera, muviri kurwisa utachiona munyama, nokuparadza kwete chete nayo utachiona, asi masero omuviri. Uyezve, mune basa kukura mabhakitiriya vakaumba infiltrates masero anogumbura uye exudate anonetsa miviri.

Sezvo chirwere mberi, uwandu immunoglobulins uye masoja zvivako ikawanda muchinjikwa kuoneka maantigen uye antibodies kwavari. The zvinhu hunoumba utachiona kutsamwisa kugadzirwa kwemajoini kuzvimba nevamiririri, vanoparadza hyaline shwashwa uye vakandizvidza pannus inotungamirwa. Izvi zvinotungamirira kurapwa zviratidzo JRA mhando.

Mushure kupora, mabhakitiriya anogona kuramba mumuviri kusvika gumi apfuura. Masayendisiti achiri kuwana zvine tsananguro iyi. Muvanhu, non-chena siyana kwekanguva kutapata, chirwere unogona recur pashure akawanda.

zviratidzo

Sei Berlioz? Chirwere wokutanga yanyarara. Zvinofanira kupfuura anonzi incubation nguva. Rinotora kusvika vhiki mbiri, asi anogona kuva reactive dzakasiyana. Ipapo yose muitiro ipfupi kuti mashoma. Kana, Asiwo, usimbe, nokuti kana zviratidzo vokutanga vanogona kuratidza pachavo mune makore mashomanana pashure kuruma. The kupfuura hunhu chirwere kubva May kusvika September, kana Zvikwekwe vari kushingaira zvokudya uye tinobereka.

Pane nguva mbiri chirwere: mangwanani uye kunonoka.

Danho rokutanga mangwanani nguva inogona kuitika acutely kana subacute. Obscheintoksikatsionnye dzinoratidzwa zviratidzo zvakadai fivha, fivha, chills, tsandanyama pari, nomusoro, kuda kurutsa, kurutsa. Dzimwe nguva pane catarrhal zviratidzo - chikosoro, runny mhino, kwazvo huro. On nzvimbo nokuruma anooneka annular erythema. Varwere vanoti munzvimbo ino kunzwa kutsva manyawi, kuvaviwa kana kunyange marwadzo. Favorite localization kuti zvipembenene - nayo muhapwa, groin uye musoro. Possible neutachiona kuti nokuruma, mikoko, conjunctivitis kana mapundu.

Chikamu chiduku varwere kuonekwe zviratidzo kutsamwa kwouropi membranes. Vanonyunyuta kuti kuda kurutsa, kurutsa, chiedza uye phonophobia, hypersensitivity, nomusoro. Vakaona yakawedzera intracranial kumanikidzwa, asi cerebrospinal mvura kungava chena.

Danho rechipiri rinowanikwa ose murwere chegumi. Kazhinji anotanga mwedzi pashure chirwere. Iyi, mberi kuzvimba meninges, zviratidzwa zviratidzo yomumuzongoza, meningoencephalitis pamwe cranial tsinga uye peripheral tsinga. A maitiro chinhu ndiye maviri ane mativi chako dzomuviri. Mwedzi mishomanana pashure pakatanga chirwere kugunun'una pakati kumwoyo varwere '. Kunoonekwa arrhythmias uye cardiac conduction mhando blockade. Dzimwe nguva pane myocarditis kana pericarditis, sezvo migumisiro muchinjikwa zvokuverengera maantigen.

Kuti Danho rechitatu zvasvika vashomanana wevarwere. Sei Berlioz? The chirwere rinovapo mwedzi anopfuura matanhatu uye anova chisingaperi, iyo inozivikanwa nokuva ganda maronda ne mhando atrophic dermatitis uye mapfundo. Chetsinga zviratidzo kuserera uye kuva akafanana tertiary neurosyphilis. Varwere vanotsutsumwa kurwadziwa ari tsandanyama uye mapfundo kuti non-zvachose hunhu.

Lyme borreliosis (chirwere cheLyme) anokwanisika kuitikawo mune vakadzi pamuviri. Kwenguva antenatal uye pakusununguka hapana zvazvinoita kupiwa pathological ezvinhu anogona vasina, asi pane mukana intrauterine hweHIV kana paumbwe vachiberekwa malformations zvomwoyo tsandanyama. Tinoziva kuti vana vevanaamai utachiona vakafa ropa mu dzinokosha nhengo kana vanozvarwa vakafa.

By empirical akataura akaratidza sei chinoumbwa nezvinhu zvakawanda Berlioz - chirwere ane zviratidzo sezvimwe wakaomarara hweHIV tsinga.

Diagnostics

Senguva dzose, chiremba inoitisa wokutanga murwere kuongorora anofananidza kubva kwaari pamusoro kwenguva, mashoko aro noruzhinji zvirwere. Anoongorora murwere zviratidzo zvipembenene ikaruma, annular erythema kana urticaria. Macheki chetsinga chinzvimbo, uyewo kugadza vakabata ECG. Kana uchifungidzira kuti zvingava Lyme borreliosis (chirwere cheLyme), vakapinda mune tsanangudzo nhoroondo chirwere, uye murwere akakumbirwa zvakaitika Kuongororwa ropa uye Urume kuti ponji kubva kumucheto erythema kuziva causative pomutumwa.

Hako akaita serological bvunzo kuziva mhando uye Borrelia marudzi, uyewo kutsunga munhu kunenge chirwere pavarwere nomumwe. Chirwere titer nokuti ongororo nechirwere anoonekwa kuti 1 kusvika 64. Sezvo nzendo pakutsvakurudza mangwanani anogona kupa venhema negative mugumisiro, Zvinokurudzirwa kudzokorora mazuva makumi maviri kana mwedzi gare gare, apo uwandu immunoglobulin zvichava zvikuru uye vachava zvakakwanira kugadzirwa kuita. Possible zvenhema zvakanaka zvavaifunga. Ivo zvinowanika varwere njovhera, kutapuriranwa mononucleosis, relapsing fivha, rheumatic zvirwere.

differential kuongorora chirwere

Berlioz kusiyanisa chirwere tinofanira kuratidza nezvipembenene encephalitis, erysipelas, uye kunyange cellulite. Iri ndiro danho rokutanga. In pakati chirwere kuoneke rheumatic mwoyo chirwere uye vadyi cardiomyopathy. Danho rechitatu pazvinhu izvi anowedzerwa chirwere Reiter uye neurosyphilis.

mabatiro

Zvinokosha kuziva nguva Berlioz - chirwere, mishonga izvo zvinogona kutora inoverengeka kana kunyange kwemakore (nokuda non-chena kutapata). In kugadzwa kurapwa inorangarira pavaipfuura kwacho, iyo etiology uye dzinokosha pathogenetic kuratidzwa.

Inorwisa mabhakitiriya kurapa vanofanira kuva varipo kubva pakutanga danho, nokukurumidza nani. Zvadaro pane mukana kuti chirwere havazofaniri nguva kuenda nadzo uye munyama, uye nokudaro kukwanisa kudzivisa matambudziko. Zvinodhaka kunorapwa vanosarudzwa akadai "Tetracycline", "Doxycycline" "amoxicillin" uye vamwe. Vane bacteriostatic kunambwa Borrelia, saka unofanira kugara kuramba pfungwa dzavo ropa.

Kana uchiri kukuvara nhengo kuwanikwa, ipapo kuronga tetracyclines ngozi zvinotapukira inokurudzirwa kuti vasarudze kuti penicillin kana cephalosporins.

Panguva imwe chete mishonga ushandiswe symptomatic uye pathogenetic kurapa kushanda vose cheni yacho yose pathological. Kuti aite izvi, mutakurire kunze detoxification muviri mumwe murwere, kupera mvura mumuviri kubvisa wakawedzera intracranial kumanikidzwa, mumuviri kurapa, kuitira kuderedza zviratidzo maronda ose cranial tsinga uye arthralgia. For yokutindivadza vaishandisa NSAIDs kana analgesics.

Kazhinji panguva kurapwa, pashure pfupi chiedza kunoitika unopinza kudzikira. Zvinonzi kwakabatana hombe kufirwa spirochetes vavo chepfu nemigumisiro. vanachiremba Modern vanonyatsoziva kuti izvi ndizvo kunoratidzwa borreliosis. Zviratidzo uye kurapwa kuti chirwere cheLyme sanprosvetrabote akataura, sezvo kana inokosha kunyatsoshanda kutanga mishonga iyi.

mataridzikiro

Yezvakaita for anoenderana nokukurumidza sei munhu anoziva dambudziko uye kurapwa. chirwere Berlioz anogona kurapwa vachiri Danho uye asashandiswe atendeuka kupinda chronization, asi nayo utachiona duku shoma muchada kutenderedza mumuviri, sezvinoita masoja zvivako aumba.

Dispensary akataura kunoratidzwa Keyes ezvinhu (zvirwere cabinet) kuti gore rimwe pashure kunotoda kupora. Varwere vakaedzwa kuti utachiona hwakakura mavhiki matatu pashure zvinoerera, ipapo mwedzi mitatu, mwedzi mitanhatu, uye pakupedzisira, pashure pegore.

dziviriro

Dzakananga kudzivirira hakuwaniki, asi munguva maberekero mwaka zvikwekwe inokurudzirwa kupfeka yezvakaita-refu sleeved zvipfeko uye mudhebhe uye kushandisa zvipembenene nomushonga wezvipembenene kudzivirira kuruma. Mushure kufamba kuva nechokwadi kuongorora pachako uye dzinovaraidza pamberi mites, sezvo ivo vari diki zvakakwana, uye ikaruma dzavo dzinenge nyarara.

Heunoi nokukurumidza muchidimbu pamusoro chirwere cheLyme, zvinokonzera, zviratidzo, ayo kurapwa mune noutachiona kuchipatara. Kungwarira mukana wokutapukirwa muchirimo uye chirimo, uye usatya kuenda kwachiremba.