Diuretic - chii? Kupatsanura uye basa diuretics

Vanhu vazhinji vakanzwa yakadaro izwi se "diuretic." Chii, tichaedza wofunga pazasi. Ichi boka zvinodhaka ane kupatsanura yayo, kuti zvivako uye maitiro

Diuretic - chii?

Diuretics anonziwo diuretics mishonga. Ndivo mishonga chakaita zvokugadzirwa kana chirimwa mavambo, izvo vanokwanisa kuwedzera excretion kuti weti pedyo neitsvo. Kuburikidza ichi, pamwe chete kunowedzera weti excretion kuti munyu nemvura, uye zvinoderedza nemvura pamwero iri in uye munyama. Nokuda kwaizvozvi nevabereki kana kunyange kunyangarika edema. Diuretics - zvinodhaka kuti zvinonzi nevakawanda anoshandiswa kurapa nokuda neBP (kwakakwidziridzwa BP). Vari anowanzoshandiswa kurapa vanyoro congestive mwoyo kukundikana, mhando uye uwandu chiropa zvirwere uye zvirwere chokuita zvakanaka kweropa kuti vanotsamwisa kurega kunotanga mumuviri. Mishonga yaiwanzoshandiswa diuretics kuderedza kana kubvisa zviratidzo flatulence, izvo dzimwe nguva achiperekedzwa PMS kana kare hwakaratidzwa panguva yekutevera. In kuzviomesera zvaidiwa kurapwa zvaiitwa uye dose diuretics regai kukonzera zvikuru nemishonga. Vava njodzi kushandisa.

Diuretics panguva pamuviri

gynecologists vakawanda vasina zano kuti vanwe usiku pamuviri diuretics. Zvinodhaka kungasava wakachengeteka nokuda mudumbu uye utano ramai. The kunambwa yakawanikwa kudaro kare. Kare, mishonga diuretic kushandiswa kuderedza edema ari pamuviri, counteracting preeclampsia and said.

Diuretics: kupatsanura

Kune mhando dzakasiyana-siyana diuretic mishonga. Woga woga ane yayo zvinokwaniswa uye utera. To musi, pane boka zvinodhaka:

• Loop Mishonga.
• Potassium-kukudzivirirai diuretics.
• zvinodhaka Thiazide.
• thiazide vehurumende.

About mapoka aya zvakazara inokurukurwa pazasi.

loop diuretics

chikamu ichi zvinodhaka ndicho. Izvi zvinosanganisira mishonga yakadai se "ethacrynic acid," "Torasemide" "Furosemide" "piretanide" "bumetanide". Pasinei chokwadi kuti makemikari mamiriro anogona zvakasiyana-siyana, diuretics izvi zvakafanana mashandiro nezvaaiita. Mugadzire izvi zvokurapa tunodzivisa reabsorption kuti zvinhu zvakadai yavaibvisa, chloride uye potassium. Musoro "loop diuretics" nokuda kwavo mashandiro nezvaaiita. Resorption rikaitika vachikwira loop pamusoro Henle mugove. Zvinonzi kuitwa ichivharira pamusoro yavaibvisa, kuiisa chlorine, potassium ari apical Kamudzira pamusoro epithelial masero tubular. Pamusana oparesheni iyi woutsinye famba-counterflow wemuTesitamende neitsvo. Uyezve, diuretics vanokwanisa iyi mhando Expand nhumbi cortex.

Side migumisiro loop diuretics

Simba kunoita mishonga izvi zvinoshamisa guru: vanogona kuwedzera weti goho ne 25%. Kusiyana nezvimwe zvinodhaka kuti vanorasikirwa kushanda pamwe normalization pamusoro Nyorera mumwe zvisingaoneke, ari loop-mhando diuretics ezvinhu akadaro zviripo. Zviri nemhaka yakasimba diuretic chiito ivo kungamutsawo nemishonga. Kupfuura isingawanzowanikwi uye zvakaoma - donhwe BP, hypovolemia, akaderedza glomerular filtration mwero uye ropa riyerere renal. Nokuda rakawedzera kubviswa sehydrogen, kuiisa chlorine uye potassium haagoni Kwabviswa metabolic alkalosis. Dzimwe nguva loop diuretics chinokurwadzai hyponatremia uye hypokalemia. Mune zvisingawanzoitiki Muzviitiko - hyperglycemia, hyperuricemia. Other nemishonga dzinosanganisira: dzungu, kuda kurutsa, utera. Medicine "ethacrynic asidhi" kazhinji chinokurwadzai zvachose kana pfupi kusanzwa, uye neutropenia. Mishonga All mhando iyi vakanga pamusoro apa, akabvisa mutumbi uchishandisa itsvo, metabolizing ari chiropa.

Zvairatidza loop diuretics

Mishonga iyi nachiremba marudzi ose nomwoyo kukundikana. Uye vari zvakakodzera kunyanya zvirwere zvakadai mwoyo kukundikana refractory mhando uye pulmonary edema. Mishonga vari zvakare kubudirira hyponatremia, hypoalbuminemia, hypokalemia, hypochloremia, uye renal kukundikana. Diuretics loop mhando kuramba kushanda apo vamwe diuretics boka, uye mubatanidzwa ayo hadzibatsiri. Ichi kukosha kwavo kukuru. Naizvozvo, ichi mhando kwakajairika - a loop diuretic. Chii, hatina kare apindura.

thiazide diuretics

Izvi yezvokurapa gadziriro uye nomukaka zvavo ( "Indapamide" "chlorthalidone" uye "Metolazone") anoshandiswa zvikuru kakawanda. Zvikurukuru, izvi nokuda mwero wavo akakwirira Absorção de Água ari nemudumbu, uyewo wakanaka azvipire murwere tolerability. Thiazide diuretics zvisinganyanyi simba kupfuura loop, asi ndinoonga kuti refu chiito vanoonekwa kuti vanhu vane zvirwere zvisingaperi zvakadai arterial neBP kuti zvinokosha mhando uye non-kwazvo congestive mwoyo kukundikana, mhando. Thiazide diuretics vari nachiremba nomumukanwa yaitonga. kazhinji Diuresis rinotanga pashure pemaawa 1-2, asi kuchirapa antihypertensive kushanda muna zvimwe zviitiko, zvingava kuitwa chete pashure 3 months dzamarudzi kurapwa. The tateguru boka iri chlorothiazide. It kunoratidzwa yakaderera lipid solubility, uye somugumisiro yakaderera bioavailability. Nokuda kwaizvozvi, nokuti muviri chaizvoizvo kunoda yepamusoro chipimo chemushonga mishonga. The mushonga "chlorthalidone" zvisanduke kunyura, saka zviri zvishoma zvikuru kuita nguva. Rinoreva "Metolazone" kazhinji anodiwa chaizvo varwere havachanyatsogoni renal basa, sezvo kusiyana nemimwe mishonga iri muchikwata ichi.

Potassium-kukudzivirirai diuretics

Panewo potassium kuchengetedza diuretics. Chii? zvinodhaka izvi inoshandiswa pakurapa neBP akabatana nevamwe marudzi zvinodhaka. Ivo kudzivisa kunyanya excretion kuti potassium muviri, inova chakajairika divi mugumisiro zvinodhaka diuretic dzimwe mhando. Hypokalemia - vasanyanye padanho potassium ari plasma. Zviri kuramba shamwari thiazide diuretics, anowanzoshandurwa nachiremba neBP mishonga. Kana potassium pamwero ipfupi kwazvo, murwere anotanga kunzwa simba, kuneta nokukurumidza, ane cardiac arrhythmia. Kuti izvi zvisaitika, pamwe zvinodhaka thiazide kazhinji ushandiswe potassium-kukudzivirirai diuretics. Vanoramba muviri pamwe zvakawanda potassium uye nezvimwe zvinokosha zvicherwa - magnesium uye calcium yakawanda. Nokudaro ivo substantially usanonoka ari kushaya yebongozozo mvura uye yavaibvisa. Kushaikwa potassium-kukudzivirirai mishonga iri sezvinotevera. Potassium mumatunhu ari yeplasma kungawedzera zvakanyanyisa (vanopfuura 5 mmol / l.). Ichi chirwere rinozivikanwa hyperkalemia. Kunogona kukonzera tsandanyama dzomuviri uye cardiac arrhythmias, kusvikira anomira. Pokumuka zvirwere zvinogoneka vari varwere renal insufficiency.

Kushandiswa nokuti nokurapa neBP

Diuretics nokuti neBP vari nekusimba. Ivo pave nokubviswa mvura kubva pamuviri, nokudaro achidzikisa BP. Itariro Chokwadi ndechokuti diuretic mishonga ndivo vanobudirira nokuda pakurapa varwere vakwegura achienzaniswa Beta-blockers. Diuretics Mishonga kuiswawo pakati pemazita wokutanga-mutsetse mishonga, iyo inoshandiswa normalize BP pamusoro. Maererano mazano kuUnited States vanachiremba, muchikwata ichi rinofanira kushandiswa kutanga Mabatirwo neBP (nyore). Nekuti guru kukosha kweropa kuzvidzora uye kuderedza zvemwoyo ngozi vari kurapwa, pfungwa rwakabhadharwa kuna metabolic zvinokonzerwa, izvo yaingowanikwa antihypertensive mishonga. Uyewo chinokosha ndiko nezvainoita weboka zvirwere zvavo nenyere-chokuita unhu.

Thiazide uye thiazide Mishonga kuti BP

Kare, BP inowanzopiwa kubatwa loop diuretics. Asi ikozvino havana kuramba kushandiswa pakurapa itsvo, mwoyo nokukundikana uye edema. Zvabuda akaratidza efficacy yakanaka thiazide-mhando zvinodhaka. Ivo kuvandudza fungidziro kuti BP. Zvisinei, kuderedza mukana coronary zviitiko apo kushandisa mari idzi haana raidudzwa sezvo zvichienzaniswa akatarisirwa zvabuda. Kushandiswa thiazide zvinodhaka kunowedzera mukana wokuti arrhythmias. Vamwe varwere anogona kunyange kamwe arrhythmic rufu. Sezvo zvinowanzoitika kusagadzikana carbohydrate uye lipid muviri, uyewo hyperuricemia. Zvinogona kuipa nokuda atherosclerosis uye chirwere cheshuga. Medpreparty boka iri rinonyanya kubatanidzwa ane potassium-kukudzivirirai diuretic.

Inotevera pamwero Kushanduka diuretics kurapa neBP thiazide simbi Ezvemutauro. Kunyanya, zvakanaka nekusimba synthesized muna 1974 tateguru wavo - Mishonga "Indapamide". The anobatsirwei kuti tiazidopodobnye zvinoreva ndoda zvazvinoita yavaibvisa reabsorption, izvo zvinoreva kuti ndoda goho kuti potassium kubva mumuviri. Naizvozvo, yaivhuvhuta metabolic uye diabetogenic migumisiro dzinenge vasipo. Zvinonzi ikozvino nekusimba kuti rinoshandiswa mishonga diki zvinodhaka "Indapamide" kunze diuretic chiito anokwanisa kuita basa rimwe karusiyamu antagonist pakati vasodilator basa uye zvinowedzera kugadzirwa prostaglandin E2.

In ezvinhu ano thiazide uye thiazide Mishonga zvinonzi nevakawanda kushandiswa kwete chete kuderedza BP, asi asiwo kuzvidzivirira nechiyero, uyewo nokuda mabatiro pakuguma nhego maronda. zvinodhaka aya kakawanda nezvaro mubatanidzwa marapirwo mapoka. Vari zvakanaka nekusimba uye saka anoshandiswa nevakawanda pasi pose.