Dubin-Johnson chirwere: tsananguro, chirwere, zviratidzo uye kurapwa

Pasinei chokwadi kuti mushonga ano kwakaita kukuru mberi uye zvirwere zvakawanda asisiri mutongo nokuda varwere, vamwe zvirwere izvi haisati aizvinzwisisa. Mumwe wavo ari Dubin-Johnson syndrome. The kiriniki, chirwere uye kurapwa chirwere ichi ndemamwe kuti utano nenyanzvi yevamwe kufarira. Funga mubvunzo uyu zvizere.

Rotor chirwere uye Dubin-Johnson chirwere - isingawanzowanikwi nhaka chirwere chiropa Similar interconnected jaundice.

zvinokonzera

Dubin-Johnson chirwere anewo rimwe zita; enzimopaticheskaya jaundice chiropa. It unovapo chokuita kutyora kukurukura kupinda bile kubva chiropa masero bilirubin.

Izvi zvinhu rinowanikwa muviri kubviswa kwazviri kana kuti dzakaparadzwa chose erythrocytes. Mhedziso bilirubin kunoitika nenzira mbiri:

• kuwedzera uwandu fuma chinobuda kubudikidza bile;
• uwandu weti duku kuenda.

Dubin-Johnson chirwere kunoitika apo kwakakanganiswa chokufambisa kuti bilirubin vachishandisa bile. Ichi chinhu apo neapo chirwere kubatwa mamwe majaya (makore anenge 20-30). zviitiko chirwere kubva pakuzvarwa kunomboitika. Mukana wokutapukirwa pashure pemakore munhu 50 makore kana vachembera usingashandi.

The majini anokonzera chirwere, Dubin-Johnson imhaka zviratidzo mutation, vanoita aina bilirubin ari chiropa uye yeEncoding nemapurotini.

zviratidzo

Dubin-Johnson urwere, zviratidzo zvacho yo zvimwe zvirwere zvakadai Somuenzaniso, kurukutika, uye ane yayo chinosiyanisa zvinhu:

• marwadzo ari mbabvu kurutivi rworudyi;
• kushaya zvakakwana havi;
• pangava zvishomanana kuvaviwa ganda;
• awanda chiropa;
• colic, izvo dzimwe nguva zvinowedzera;
• kurutsa;
• tembiricha kuwedzera.

Kuratidza vari yakakura nokuda zvinotapuriranwa, zvikuru mumuviri uye mupfungwa zadzisa. Vakadzi, zvinobvira kusembura pashure yaunodya kuti pamuviri.

boka nengozi

Iyo boka revanhu vanofanira kuva vasingafariri mashoko chirwere?

Chirwere chacho chichigarwa nhaka. Kana mhuri vakanga vana nehosha iyi, vaviri ava padariro kwekuronga pamuviri zvinokosha kupfuura zvose miedzo, miedzo zvakafanira uye kubvunza nyanzvi. mazano avo inoshandawo kune vakaroorana avo, kusanganisira mumwe kuwanana kana zvavo pedyo nehama vakatambura Dubin-Johnson syndrome.

The chirwere muitiro

Nepariri, chirwere chacho rakajairika pakati pevaJudha Iranian. nhamba yavo kunosvika 70% of zvachose kurema kurwara.

Zvakakosha kuti anenge asina zvinouraya Dubin-Johnson syndrome. MUENZANISO varwere inosimbisa izvi. Doctors amutsvaka upenyu hunotarisira varwere nechirwere ichi uye vakagumisa kuti haitungamiriri rufu.

About 25% of varwere vanorwadziwa zvakarurama hypochondrium. Nemamiriro chiropa asina kukanganiswa, hapana deformation ari syndrome. Asi panguva imwe chete riri nyama dzawo kuonekwa mavara matema, zvichiguma muviri Kuchinja ruvara aro manyoro kana shava. Ichi chinowanikwa chirwere inonzi Chocolate Chip makeke. Izvi zvinoitwa rusvingo metabolites secretion.

The chirwere ane yakanaka fungidziro, kunyange zvazvo anogona kuramba yose upenyu murwere.

Tafura pazasi inoratidza mashoko pamusoro mamiriro zvomukati wevarwere.

Diagnostics

Dubin-Johnson urwere, nechirwere izvo kunoitika mumatanho akawanda, pakutsvaga Analyses.

• Zviri fanira kuti Ultrasound ari mudumbu.
• General ropa uye weti nemiedzo.
• Analysis ropa uye weti kuti bilirubin. Kazhinji, vane kukwirira.
• Mimwe fenobarbetalom.
• Sezviratidzo ose nehepatitis.
• Sample bromsulfaleinova.
• Coproporphyrin kukosha zviratidzi iri weti pazuva.
• Zviri makemikari muropa.

Shandisa dzimwe nzira nechirwere.

In pamberi Dubin-Johnson chirwere varwere vane kushanyira chiremba.

Mushonga uye Kudzivirira

Dubin-Johnson urwere, izvo kurapwa hakudi kugamuchira anokosha kugadzirira nemauto matanho:

• kuomerera vaitofanira kudya, kushandiswa B mavhitamini, vasiri preservatives;
• zvinoderedza kushushikana ezvinhu;
• rutapudzo kurovedza muviri;
• Kuramba zvinwiwa zvinodhaka;
• Kugara richiona nezvezvabuda bilirubin siyana pamusoro upenyu murwere upenyu.

Zvinokoshawo kuyeuka kuti pamuviri anogona kuwedzera chirwere. Zvinodhaka kubatsira kurapa chirwere Dubin-Johnson, Pari kwete yakatanga.

Saizvozvowo, hunhu hosha iri Rotor syndrome.

tsananguro pfupi

Rotor chirwere hazvina nhaka chirwere kunokanganisa chiropa. Kaviri kuchinja chokuendesa bilirubin, enzayemu mabasa kuramba muupenyu. Tinogona kutaura kuti hosha iri lightweight muchimiro Dubin-Johnson chirwere inorondedzerwa pamusoro. Zviratidzo airatidzawo zvishoma manyoro.

The chirwere anogona kuratidza sezvo kubva pakuzvarwa uye muduku. Bilirubin muropa murwere anogona kuva akasununguka uye vakasungwa. Pane musiyano pakati gallbladder.

Rotor chirwere kunoratidzwa ndechokuti mune hepatocytes hapana zviri shava pigments. Not pane kushanda, iyo inozivikanwa se Chocolate Chip makeke. The mhaka chirwere siyanei kubva Dubin-Johnson syndrome. Panyaya iyi, chiropa havagoni kukurira Absorção de Água kuti bilirubin. Somugumisiro, kukundikana undigested fuma kunyika ropa. On hwaro ichi, murwere hwapedyo giperbulemiya. Yakanaka fungidziro chirwere chacho.

Panguva nechirwere lidofreninom chiropa, nduru dundira uye ducts zviri kuoneka.

urwere zviratidzo

Signs Rotor chirwere zvakafanana zvikuru zviratidzo zvechirwere chirwere Dubin-Johnson:

• Zvakakwana akaratidza jaundice.
• Kunzwa shungu pamuromo.
• Marwadzo zvakarurama hypochondrium.
• Apo Dubin-Johnson urwere, chiropa varwere yakawedzera kukura. Kana ari Rotor chirwere ichiwedzerwa chete dzimwe nguva.
• Yakakwirira kwevari bilirubin muropa.
• chiropa basa miedzo muupenyu.
• miedzo ropa pasina kuchinja.
• Chiropa bioptome haisi kuunganidza pigments.

Fungidziro kazhinji zvakanaka, kuti chirwere kunoitika kwemakore akawanda, kunyanya zvinopesana utano hwevanhu.

chirwere of urwere

The chirwere unogona chete kuiswa panguva misoro chirwere pamusoro muviri.

Studies ichiitwa murabhoritari kubatsira zvinoratidza zvakawanda zviri bilirubin muropa. Nokuti nechirwere zvakakosha kuziva uwandu coproporphyrin huri weti.

Varwere vakawanda, chirwere mberi pasina zviratidzo.

Kana nechirwere kuna Rotor chirwere vanopedza chiropa ongororo: yake X-ray uye Ultrasound. Saizvozvowo pachisara vanosangana nduru dundira uye ducts.

dziviriro chirwere

General matanho ndeinotevera:

• rutapudzo kurovedza muviri;
• mishonga yezvirwere akabatanidza rotor chirwere;
• Dzivisa kushushikana mupfungwa.

Zvinhu zvizhinji pamusoro bilirubin muropa

Bilirubin kunowedzera nokuti kwezvikonzero zvinotevera:

• kuzvidya mwoyo;
• rwara kudya, kudya kukanganisa;
• kushandisa zvinodhaka;
• nokunyanyisa kunwa doro.

pakurapa chirwere

Common nzira kubvisa chirwere ikoko. Zvisinei, zvinofanira kuita zvinoenderana matanho. Sezvo zvinodhaka zvaunofanira kutora zvinoreva kuti goho bilirubin kubva mumuviri. Bile kazhinji zvinodhaka anoshandiswa.

Sarudzai yakakodzera kurapwa kuti abatsire chiremba.