Fibrinogen - wokuyera uye zvokurwara

In adzidze kweropa gadziriro, indekisi ichi akatsunga hazvo. Zvakakosha kuti mamiriro ezvinhu akasiyana. Pamberi pokuvhiyiwa, kugadzirira mwana, zvemwoyo uye anogumbura nezvirwere ropa nguva dzose kusarudza fibrinogen. Norma akanga asiri saizvozvo vakuru uye vacheche. Vakadzi vane pamuviri, yokumusoro muganhu waro yakakwirira zvikuru. Asi omerera zvinodiwa gare gare. Chokutanga, ngatimbotaura pamusoro chii kazhinji inomirira fibrinogen.

Maererano zvavo nemakemikari chimiro, ndiko - puroteni. It Anonziwo zvakawanda zvinokonzera pakugwamba I. rinobatanidzwa kwokupedzisira padariro pakugwamba ropa, zvinoti - pakugadzirwa ropa clot. In hwakanaka hwevanhu fibrinogen muropa aripo ari yakanyauka mamiriro.

Kana activation zviri coagulation ezvinhu panguva yayo yokutanga Danho pasi zvinoitwa nevamwe pakugwamba zvinhu akaumba thrombin.

In chechipiri chokutambudzika nokupesvedzera pakugwamba fibrinogen uye thrombin dzainamatira dzikwanise insoluble fibrin, izvo anoumba hwaro ane clot ropa, mumwe thrombus. Kunosanganisira kurega ropa. Nokudaro zviri pachena rinoreva kuti muviri inofanira fibrinogen. Ndozvakajairwa iri fuma munhu mukuru utano munhu anoenderana 2-4 g / l. In achangoberekwa vacheche, mwero iri shoma - 1,25-3 g / l. Asi unomutswa panguva nepamuviri 6 g / l. Izvi zvinonzwisisika. Pashure pezvose, muviri mumwe mukadzi anogadzirira kusununguka, izvo nguva dzose chokuita ropa. Saka, zvinoitika, mwero fibrinogen muropa hakuna kufanana vose. zviri wakakwirira zvikuru kuvakadzi vane mimba.

"Hongu, asi kupi kubva?" - zvamunokumbira. Zvakaratidza kuti ichi pakugwamba chinhu anogadzirwa chiropa uye masero ari reticuloendothelial hurongwa. Saka, muna zvirwere chiropa, zvakadai chiropa kana cirrhosis rinorema fibrinogen vane wokuyera - kwete pe2 g / L, dzimwe nguva ipfupi kuti vashomashoma nhamba. Izvi zvingaita kuti dzakasiyana-siyana ropa, ropa paganda uye mucous membranes. Kutora zvimwe zvinodhaka (androgens, anabolic steroids) kunogona kuderedza ayo mwero. Mune zvimwe zviitiko, pane tinozvarwa zvikanganiso dzidzo chinhu I. iyi inonzi afibrinogenemia kana hypofibrinogenemia.

The unopinza kuderera pamusoro fibrinogen iri kuchengetwa rechipiri uye rechitatu kutotanga dessiminirovannogo intravascular coagulation syndrome. Izvi rinorema pathological ezvinhu, kazhinji anopera hune ropa nokuda paumbwe midziyo duku vakapararira fibrin clots. Wavo zvokuti fibrinogen depleting mumatanda. Chenjera fibrinolysis, muitiro kuti chokuita nokusimbaradza pokufa fibrin, uyewo achiperekedzwa vasanyanye pakati fibrinogen. It shoma chisingaperi myeloid neleukemia, pamwe kushayikwa vhitamini B12 mumuviri uye S.

Mune dzimwe zvirwere, nekusiyana, pane zvakawanda fibrinogen. Norm kupfuura kukosha coagulating chinhu akaenzana 4 g / l. Asi rheumatic, zvirwere, anogumbura urongwa, kenza, thrombosis uye infarctions chinhu I anoyera anogona yakawedzera 1.5-2.5 nguva. Fibrinogen anonziwo rikwanise kutotanga mapuroteni, sezvo michero yayo achabatsirwa chakasimba anogumbura chirwere. Padanho mapuroteni iyi kukuvara, kushandiswa nomumukanwa nhumbu uye inonzi estrogen pashure kuvhiyiwa.

Pane uchapupu hwokuti yakakwirira fibrinogen yomuropa anogona anoteverwa chitarisiko shamhu uye mwoyo kurwiswa. ukama pachena pakati zvirwere izvi uye ayo yapfuura anotoita rakawanikwa tsvakurudzo.

Kuti tizive padanho fibrinogen, unofanira kupfuura usina chawadya ropa kubva tsinga. Ropa inocherechedzwa bvunzo chubhu pamwe anticoagulant.