Kugadzirira "Sultasin": mirayiridzo yekushandiswa

"Sultasin" inorwisa mabhakitiriya ari eboka re penicillin. Iyo yakagadzirwa ine beta-lactamase inhibitor. Chirwere chacho chinonzwisisika kune mabhakitiriya mazhinji, yakagadzirirwa kushandiswa kwekushandisa.

Mushonga unobudiswa mumamiriro akaita sei, chii chinowanikwa mukugadzirwa kwayo?

Mushonga unobudiswa muhupfu. Ichi ndicho chikonzero chekugadzira sarudzo, ine injections inogadzirwa. Iyo inogona kuva nehuwandu hweupfu - 0.75 kana 1.5 g.Zvashandi zvinoshandiswa zvinoshandiswa nenzira ye sodium munyu, iyo yakagadzirwa ine midzi miviri miviri-sulbactam uye ampicillin, imwe neimwe ine 250 uye 500 mg mune rimwe bhodhoro.

Chiito chemishonga

"Mirayiridzo ye" Sultasin "yekushandisa maonesheni seBactericidal antibiotic, kusagadzikana neacids. Chirwere ichi chinovhiringidza kutanga kwe peptidoglycan, nemhaka yekuti masero emadziro emakiromita haana kuwedzera.

Ampicillin inoreva semisynthetic antibiotics, ine bhaptericidal effect, inokanganisa kuumbwa kwebhakitiriya masero masvingo, semugumisiro wekuwedzerwa kwekuwedzera kwezvirukirwe zvisingaitiki. Ampicillin haina kuputsa pasi pechiito cheAicids.

Sulbactam inhibitor ye beta-lactamases, haina antibacterial effect, uye inobatsira pamagetsi asingagadziri e beta-lactamase. Chirwere ichi chinoshandiswa kurapa mamiriro ezvinhu anokonzerwa nevanaerobic mabhakitiriya, gram-negative uye gram-positive microorganisms, inogona kuparadza zvimwe zvezvipenyu. Kana paine hutachiona husingaiti beta-lactamase, basa rekugadzirira Sultasin rinofananidza mirayiridzo yekushandiswa kune chiito chinoshandiswa na ampicillin oga.

Pharmacokinetics

Mushonga pashure pokushandiswa unowanikwa munenge zvose zvinodhaka uye masukisi emuviri womunhu. Muhupo hwekuvhiringidza zvirongwa, kupora kwechirwere ichi kune cerebrospinal fluid inowedzera zvikuru.

Somugumisiro wehutungamiri hwemishonga inonzi intramuscularly uye intravenously, zvinhu zvinoshanda zvinowanikwa muropa mune zvakanyanya kuwedzera. Kusarudzwa kusarura kwechirwere kunoitwa mukati memawa imwe chete. Kubviswa kwaro kubva mumuviri kunoitwa neinso, vazhinji veSultasin remedy (kubva ku70 kusvika ku80%) vane chimiro chisina kuchinjwa. Uyezve, kubviswa kwechikamu chechirwere chinoitwa nechiropa. Mushonga wacho unowanikwa mumukaka wechipfuva, unogona kuputsa miganhu yenzvimbo inoputika. Izvo zvikamu zvinotakura zvinowanikwa zvishoma nezvishoma metabolism, inenge 25% ye "Sultasin" yakanyanyiswa semetabolites.

Zviratidzo

Kugadzirira kweSultasin kunokurudzirwa kushandiswa mumamiriro ezvinhu akadaro:

• Zvirwere zvinokonzera nhengo dzeNIT uye nhengo dzokufema;
• Meningitis;
• Zvirwere zvinotapukira umo mapfundo nemapfupa zvinokanganiswa;
• Sepsis;
• Zvipembenene zvemuviri wepamuviri uye bile ducts inokonzerwa nemaabhakitiriya;
• Peritonitis;
• Zvironda zveganda, zvinyoro zvinyoro;
• Septic endocarditis;
• Utachiona, hunokanganisa maitiro edzimba uye urinary tract;
• Gonococcal infection;
• Scarlet fever.

Uyezve, chirwere ichi chakakodzera matanho ekudzivirira anotsvaga kudzivirira zvinetso zve postoperative. Mushonga unoshandiswa mune zvinotapukira, iyo causative agent iyo iyo bhakitiriya inofanirwa nayo, uye kuitira kuti kudzivirira kusimbiswa kwezvakaipa zvisati zvaitika mushure mekuvhiya, apo panguva ipi zvayo inoshandiswa manipulations mumapapiro uye nhengo dzepamuviri dzakaitwa.

Contraindications

"Mirayiridzo ye" Sultasin "pamusoro pekushandisa haibvumi kushandiswa kwekutapukisa mononucleosis, hypersensitivity uye panguva yekurota.

Apo pavanoshandisa mushonga uyu, vakadzi vane pamuviri vanoda kunyatsotarisirwa, sekurapa kwevarwere vane ruzivo rusina kukwana kana kusakundikana kwepfungwa.

Kusarudzwa kwechirwere, kurapa nekushandiswa kwayo

Mishonga inoshandiswa nenzira dzomukati uye dzomukati. Kutungamirirwa kwechirwere kunofanira kunge kunonoka. Nokushandiswa kwechisimba, kurapwa kunoitwa kwemazuva mashanu kusvika kune manomwe. Kana paine chido chekuwedzera kurapwa, ipapo mhinduro inopindwa intramuscularly.

Chiyero chezvinhu zvinoshanda - ampicillin uye sulbactam - is 2: 1. Kana chirwere ichi chinorondedzerwa senzira iri nyore, inotarisirwa, kubva ku 1.5 kusvika ku3 g, inotarisirwa nekuparadzanisa kaviri mushonga we "Sultasin". Mirayiridzo yekushandiswa kwejojovo nehuwandu hwehutachiona hwechirwere hunorayira kuita katatu kana mana, uye zuva rinofanira kushandiswa kubva pa3 kusvika ku6 magamu emishonga. Nzira yakaoma yehutachiona hunotanga inotanga kuiswa kwe 12 g yemishonga ine nguva imwechete yakafanana neyakamboitika.

Apo gonorrhea isina zvinetso, zvakakwana 1.5 g yemishonga, inoshandiswa kamwechete. Vachecheche, vane makore avo haapfuuri vhiki imwe chete, uye vana vasati vasvika mujeri, vane nguva yenguva gumi nemaviri, mhinduro yeSultasin. Mirayiridzo yekushandisa inokurudzira kuti vana vagovera 150 mg yemari pa kilogram yehutano hwevana. Uyu ndiwo mwero wezuva nezuva, uyo unosanganisira ampicillin uye sulbactam muyero we100 uye 50 mg / kg, maererano. Penguva yekurapa, chido chinodiwa chemishonga kumwana chinoshandiswa zuva rimwe nerimwe kusvika katatu kusvika mana.

Kuti udzivirire zvinetso, nyanzvi dzinoshandisa 1.5-3 g yemishonga munguva yeanesthesia, gare gare (mukati maawa makumi maviri mushure mekushanda) mukana iwoyo wejenisi unoshandiswa, asi kwete kamwe chete, asi panguva dzenguva maawa 6-8.

Kurapa kunotora mazuva anenge mashanu kusvika kune gumi nemana. Apo zviratidzo zvose zvechirwere zvanyangarika, uye kutonhora kwemuviri kunowanzoitika, kurapa kunoitwa kweimwe mazuva maviri.

Kuwedzerwa kusinganzwisisiki kwemishonga inonzi Sultasin inokurudzirwa kuti ishandiswe mukukundikana kwetsitsi, iyo inowanikwa mune chimiro chisingaperi chine mvumo ye 30 ml / min.

Kugadzirira kwegadziriro

Kana ukaronga kuita parenteral kutungamira kwechirwere, chirongwa ichi pakarepo mushure mekugadzirirwa kunopiwa kumurwere. Kana Sultasin inofanira kutarisirwa mukati, iyo pfupfu inonatswa nemvura yezvijakisi muhuwandu hwe 2 (duku vial) kana 4 ml (bhodhi rine 1.5 g yeagadziri akaoma), zvichienderana nehuwandu hwehupfu. Unogona kushandisa imwe sarudzo. Iyo inyanzvi yejojo inofanirwa kugadzirirwa neyanyanzvi, sezvo chete iye anogona kuzviita zvakanyatsonaka.

Kugadziriswa kwemuti mumwe chete sarudzo yekutengesa kwemukati kunoda kushandiswa kwe sodium chloride kana 5% glucose.

Zviitiko zvakashata

Wakagadza Sultasin here? Mirayiridzo yekushandiswa, kuongorora kunotsvaga njodzi yekukura kwekushushikana kwomuviri kubva kune dzimwe dzedzimwe sarudzo dzaro, dzakadai sekudya kwekudya, iyo inotyisa yenheyo. Ikoko kunogona kunge kusina kukodzera mukushanda kwe hematopoiesis, kushandiswa kwemagetsi kunogona kuitika uye mamwe mabhakato ematara anogona kuchinja. Mune vamwe varwere kugadzirisa kwenharaunda kunoonekwa, nekutengesa kwepraveous - phlebitis, nekushandiswa kweimwe nzira yekugadzirisa marwadzo panzvimbo yejojo. Pakati pezvimwe zvinokanganisa - zvinokonzerwa nekureba kwenguva refu (candidiasis, superinfection).

Overdose

Kuwedzerwa kwemishonga inokonzerwa nemishonga kunogona kutungamirira kuhutano hwekurwadziwa, nokuda kwekubviswa kwaunofanira kubvisa mishonga uye kushandisa salmin, kuitira kuti mvura-electrolyte yakaringana iri pamwero wakakodzera, uyewo zviratidzo zvechirwere.

Special instructions

Zvakakosha kuti uzive nezvehutano hweSultasin (mazano ekushandura, tsanangudzo) kune avo vanokonzerwa nekugadzirisa zvinokonzerwa nemararamiro ega, nokuti kana yakabatanidzwa ne-cephalosporin antibiotics uye hypersensitivity penicillin, pane ngozi yepamu-yekugadzirisa.

Kurapa pamwe nedzidzo kunoda nguva dzose kutarisa kwetsvo, chiropa uye kushanda kwe hematopoiesis. Mumamiriro ezvinhu apo pakanga paine kuwedzera mukukura kwe microflora, kunzwisiswa nemishonga, murwere angave ane superinfection. Mumamiriro ezvinhu akadaro, kuchinja kunodiwa kunowanikwa muhurongwa hwekurapa.

Munguva yekurapa kwechipembenene, bhakteriolysis inogona kuitika. Mukana wekubatanidza "Sultasin" nemimwe mishonga inofanira kuongororwa nenyanzvi.

Analogues, kuongorora

Kana mirayiridzo yekushandiswa isingabvumi kushandiswa kweSultasin, zvakafanana, zvakadai seUnazin, iyo inotsiva chinhu chinoshanda, Sulbacin, Sulacillin uye Ampiside, vanosarudzwa nechiremba anoenda, achifunga nezvehutano hwehutano. Dzimwe nguva analogu inounza zvakawanda zvakapfurikidza neyakasikwa, sezvo yakanyatsokodzera murwere uye inofananidzwa nemamiriro emuviri wake.

Vatengi vanogadzikana nemutengo wechirwere, asi vazhinji vanotya nehuwandu hwekushushikana kwakaipa. Sezvo zvipupuriro zvinoratidza, mumamiriro ezvinhu apo mishonga yakashandiswa nevakadzi munguva yekuzvitakura, pakanga pasina kuipa kwakanyanya pane utano hwemwana. Vamwe varwere vanoratidza madzimai maduku. Kuzvidzivirira kana kuti hazvina kuratidzwa zvakanyanya, zvakakosha kuita kurapa kwakakwana naSultasin. Mirayiridzo yekushandiswa kwevana inobvumira kurapwa nemudzvinyiriri uyu, zvisinei, kutonga nekuongororwa, mune dzimwe nguva zvinetso zvakakomba zvinoitika, zvakakomba migumisiro inoonekwa, uye dzimwe nzira dzinoda kurapwa.