Majekiseni "cefotaxime": mirayiridzo kushandiswa, zviratidzo, mutengo. Reviews kugadzirira

Hazvina chakavanzika semisynthetic mishonga vane chakarondedzera chiito. Formulations kwakadaro anoshandiswa kurapa siyana anogumbura uye zvirwere zvinotapuriranwa. Zvisinei, usati kurongera chinodhaka, chiremba anofanira kurayira murwere kuti vanochinja kuongorora zvokurapa. Nzira bedzi kufunga izvo mushonga tichabudirira kuoneka ari kurapwa chirwere.

majekiseni "cefotaxime" vachishingairira kushandiswa pakurapa urogenital ezvinhu, uyewo kufema turakiti. Zvinoumba chigadzirwa ichi, ayo contra-zvairatidza, chipimo chemushonga uye nzira chourongwa tinotarisira zvishoma mberi.

Zvinoumba, description, chimiro uye kavha mishonga

Ndezvipi zvinhu chine mushonga "cefotaxime"? Majekiseni (vana chipimo chemushonga kuti mumiririri uyu wakaisirwa nomumwe) zvinosanganisira yakadaro chinoshingaira fuma, akadai cefotaxime (sodium munyu).

Kugadzirira pachahwo chena kana yellowish upfu, yaishandiswa achigadzirira kugadzirisa aiendeswa intravenous kana intramuscular jekiseni.

Mishonga inowanika girazi ndiro, mumapepa makatoni.

pharmacological ehupfumi

Wanga uchiziva kuti ari chinodhaka "cefotaxime"? Mirayiridzo kushandiswa (majekiseni vana - muedzo hakusi nyore, asi chii kana nekurovererwa akadaro aibva) rinoti kuti varwere vaduku zvinodhaka riri ushandiswe nokungwaririra akaipisisa, nokuti Semi-chakaita zvokugadzirwa mushonga. Its vanoshingaira chinowanikwa rechitatu chizvarwa cephalosporins.

Mishonga inoshandiswa parenterally. Hazvina basa pamusoro giremu-akanaka uye giremu negative utachiona kuti aratidze refu kurwisa kune aminoglycosides, sulfonamides uye penicillin.

Nheyo inorwisa utachiona chiito zvinodhaka izvi inobva kukwanisa rayo tunodzivisa basa transpeptidase. Izvi zvinoitika nokuda ichivharira peptidoglycan.

Kinetics zvinodhaka

Sei takabatikana "cefotaxime"? Abstract (majekiseni - ndicho chete chimiro vakati zvinodhaka) inoratidza kuti, pashure intramuscular Kutarisirwa soro wevasungwa zvinodhaka muropa vakachengeta pashure maminitsi 35. Inenge 27-40% kubva vanoshingaira chirungiso iri vakasungwa mapuroteni eplasma.

Bactericidal mugumisiro zvinodhaka rinovapo kwemaawa 12. The mushonga rinowanikwa nduru dundira, myocardium, mapfupa uye nyoro tishu.

Hatigoni kutaura kuti yezviri chezvinonhuwira kwezvinodhaka ichi anokwanisa kuyambuka placenta uye kutsunga iri pleural, peritoneal, synovial, cerebrospinal uye pericardial mvura.

The weti goho anenge 90% of zvinodhaka.

Intramuscular kwokubatsira mushonga hafu-upenyu maminitsi 60-90, apo intravenous majekiseni - 1 hr. Part yezviri chirungiso inenge yabudiswa pamwe bile. Cumulation zvinodhaka riri kuchengetwa.

zvairatidza

Ndezvipi zvirwere vanofanira kushandisa mushonga "cefotaxime"? Mirayiridzo yokushandisa (majekiseni, mutengo uko dziri pazasi vanofanira chete kupiwa chiremba) rinoti kuti medicament inoratidzwa kuvapo zvinotapukira.

Zvinonzi chaizvo rinowanzoshandiswa zvinotevera pathologies ari kufema hurongwa:

• nemabayo;
• pleurisy;
• abscesses;
• bronchitis.

Zvinonzi zvakare vaiona nzira chaiyo:

• kwemabhakitiriya yomumuzongoza;
• endocarditis;
• postoperative yematambudziko;
• septicemia;
• nyoro zvinyama noutachiona uye mapfupa;
• Chirwere cheLyme;
• zvirwere Urinary turakiti, huro, nzeve, mhino, itsvo;
• Zvirwere mapfundo mapfupa;
• abdominal noutachiona;
• Zvirwere yakaitika tikafunga immunodeficiency.

Tinofanira kuonawo kuti kwepfuti "cefotaxime" kazhinji ushandiswe kudzivirira zvirwere kuti yakatanga pashure pokuvhiyiwa (kusanganisira urology, Obstetrics and Gynecology, gastrointestinal nhengo, uye zvichingodaro. D.).

Contraindications kuti kushandisa zvinodhaka

Kuti mashoko sei kuti kugumisa bara "Cefotaxime," tichazvidudzira pazasi. Zvinofanira kucherechedzwa kuti chokushandisa ichi hachisi mazita refu zvikuru contraindications. Maererano mirayiridzo, mishonga iyi haungopiwi:

• ropa;
• pamuviri;
• nomumwe hypersensitivity kune basa zvinoriumba;
• enterocolitis (kusanganisira nhoroondo).

Zvinoita kuti ataure mhinduro yacho mwana "cefotaxime"? Majekiseni vana (inofambiswa kubudirira akati zvinodhaka zvichakurukurwa panopera nyaya) anobvumirwa kuita izvozvo chete pamusoro kusvika makore murwere 2,5 makore (nokuti / m).

Nokungwarira mishonga hwakanyanya ushandiswe achangoberekwa panguva pamukaka (sezvo mushonga riri shoma yabudiswa muna mukaka), uyewo kuvapo chisingaperi cheitsvo uye maronda colitis (kusanganisira nhoroondo).

Mune zvokurwara pamusoro renal uye hepatic hurongwa, murwere aifanira kuongorora zvimwe vezvokurapa kuti vawane vafunga pamusoro kusavapo contraindications kuti mishonga.

Drug "cefotaxime": mirayiridzo kushandiswa (majekiseni)

How kudyara upfu kurudyi? Kuti tipindure mubvunzo uyu, tinofanira kuenda akanyudzwa mirayiridzo. It rinotsanangura uchida nzira yako injectable zvingaitwa.

Saka, nokuti intravenous vaitarira (jekiseni) 1 g pamusoro upfu rokugadzirira rakasanganiswa 4 Rine mamiririta emvura majekiseni (chena). mishonga Ready jekiseni zvishoma nezvishoma pamusoro maminitsi 4-7.

For intravenous aizomupa 1-2 g upfu vari rakasanganiswa 50 kana 100 ml yacho solvent. Sezvazvakanyorwa rinoshandiswa 0,9% yavaibvisa chloride kana 5% shuga (dextrose). Nguva chourongwa kwakadaro - maminitsi 55-65.

For intramuscular kwokubatsira zvinodhaka upfu akanga ichiputswa 1 g 4 Rine mamiririta solvent. Sezvazvakanyorwa rinoshandiswa nemvura jekiseni kana 1% lidocaine mhinduro.

Saka, vaiona mushonga inogona kupiwa nomutsinga kana ndege, uyewo intramuscularly.

kazhinji mishonga ushandiswe kuna vakuru uye kuyaruka pamusoro makore 12 achirema makirogiramu anopfuura 50. Muna chenjera vanoda kushandiswa kwayo pakurapa vana vaduku.

The chipimo chemushonga zvinodhaka

Zvino imi munoziva chii chinogona rakasanganiswa majekiseni "cefotaxime". Asi chii chinonzi chipimo chemushonga yavo? It kunobva chiratidzo uye kukomba kwechirwere chacho.

Nokuti zvirwere zviri urogenital turakiti, uyewo nyore noutachiona kugadzirira chinotarisirwa nomutsinga kana intramuscularly muna 1 g maawa ose 9-12.

At mwero Zvirwere - ose maawa 1-2 g 12.

In nyore chenjera mwandabvu medicament chinotarisirwa intramuscularly panguva chipimo chemushonga kuti 1 g (kamwe).

In zvirwere zvakakomba (semuenzaniso, yomumuzongoza) kugadzirira rinoshandiswa nomutsinga pana 2 d maawa ose 6-9. The kunonyanyisa dose pazuva iri 12 d Duration kurapwa wakaiswa nomumwe.

Nokuti kudzivirira zvirwere pamberi varwere kuvhiya panguva induction pamusoro yokutindivadza chinotarisirwa kamwe "cefotaxime" pane imwe dose kuti 1 g Kana waida kuti jekiseni akadzokorora pashure pemaawa 6-12.

At chikamu caesarean panguva okusungisa uchidzifukidza achiine rukuvhute tsinga kugadzirira chinotarisirwa nomutsinga mune imwe mari 1 zvimwe 6-12 maawa kuti mamwe jekiseni zvakafanana dose.

Mirayiridzo vana

Kana majekiseni zvakakodzera "Cefotaxime" achangoberekwa uye vakurumidze vana pasi pemakore vhiki imwe raitongwa nomutsinga mune imwe mari 50 MG pa makirogiramu kurema muviri wose maawa 12. Pazera vhiki 1-4 zvinodhaka chinotarisirwa panguva iyoyo dose, asi ose 9 maawa.

vakura makore 2.5 vana yairema makirogiramu asingasviki 50 medicament raitongwa intramuscularly kana nomutsinga mune imwe mari 50-180 MG pa makirogiramu uremu muviri (4 kana 6 dzekushumira).

In zvirwere zvakakomba, kusanganisira yomumuzongoza, nezuva chipimo chemushonga zvinodhaka ichiwedzerwa kuti 100-200 MG pa makirogiramu. Kana jekiseni iri kuitwa nomutsinga kana intramuscularly mune imwe mari 4-6 nguva pazuva. The kunonyanyisa dose pazuva iri 12 d

nemishonga

Tikafunga "cefotaxime" mushonga pavarwere zvingamuka wanda zvakadai omunharaunda, yakadai se:

• marwadzo pamusoro intramuscular jekiseni;
• phlebitis, aifamba nenzira intravenous aizomupa.

Angasanganisira zvinotevera nemigumisiro:

• cholestatic jaundice, pseudomembranous colitis;
• chiropa, kuda kurutsa, hypoprothrombinemia;
• rakawedzera alt, AST, hemolytic kupererwa neropa;
• manyoka chirwere, ungaderedza platelet kuverenga;
• kurutsa, neutropenia.

Mune zvisingawanzoitiki Muzviitiko, sema mhinduro (kuwedzera kwenhamba eosinophils, angioedema uye kuvaviwa), uye interstitial nephritis uye candidiasis.

Kana kucherechedza zvimwe Migumisiro zvinoda kurapwa, uye nokuzvidzora nemishonga kukanzura.

Price uye analogues of mushonga

Mari mushonga pasi kufunga kunobva pemambure varikumahombekombe uye okutengesa nzvimbo. Paavhareji, ampoules, ndiro (5 hrs 1 g) inogona kutengwa 160-170 rubles.

Kana mukakumbira rinoita medicament anobvumirwa kutsiva chete achishandisa dzakadai "Claforan", "Tsefabol" uye "Tsefosin".

Zvisinei, tinofanira pakarepo kuzivikanwa kuti kushandisa mishonga iyi inogona kuva chete pashure zano chiremba.

Reviews zvemishonga inorwisa mabhakitiriya vamiririri

In varwere chiremba mushonga zvinowanzooneka ushandiswe sechinhu inorwisa utachiona mumiririri. Kazhinji, izvi zvinoitwa zviitiko apo vamwe mishonga musapa yakanaka kuchirapa kushanda.

Consumer wongororo kuti majekiseni "cefotaxime" anopfuura zvakanaka. Murwere Mishumo zvisimbiswe ayo yakakwirira inorwisa utachiona efficacy. Zvisinei, unogona kuwana mhinduro yakadaro, izvo zvakajeka inoreva kuvapo vakawanda nenjodzi kwakacherechedzwa pashure kurapwa (bloating, goiter, colic, etc).