MMF (mycophenolate mofetil): tsanangudzo, zvakafanana

Mofetil mycophenolate (INN Mycophenolic acid) chikamu cheboka remunosuppressants. Ngationgororei zvakajeka, mune zviitiko zvipi zvinokosha kushandisa chirwere ichi, chii chinopesana nemashandisirwo ayo uye nemigumisiro.

Mukuwedzera, tinodzidza kana kune mishonga yakafanana mune zvemazuva ano.

Basic Information

Mofetil mycophenolate inowanikwa nenzira yakaoma gelatinous capsules yenzou yenyanga dzenzou nemafuta machena mukati.

Iwe unogona kutenga chiremba mu pharmacy chete kana iwe une mishonga kubva kuchiremba.

Irofu rehupenyu hwechigadzirwa makore maviri. Chengetedza iyo pakushambidza kwemadigiri 25.

Kuti uve nechinzwisisiro chezvinhu zvinoshandiswa nemishonga yatinenge tichifunga (mycophenolate mofetil) inoratidzika seyo, mufananidzo uri pamusoro unoshanda semuenzaniso wakanaka.

Maitiro ekugadzirira

Rimwe capsule rine 250 mg yezvinhu zvinoshanda (mycophenolate mofetil). Mukuwedzera, zvibatsiro zvekubatsira zviripo, zvakadai se croscarmellose sodium, microcrystalline cellulose, magnesium stearate uye povidone.

Pharmacokinetics

Mushure mokushandisa mushonga uyu, unonyatsopindira uye unopedzisa pre-systemic metabolism. Panguva imwecheteyo, kuiswa kwezvinhu zvinoshanda mumaplasma hazvionekwi nekuda kwekutsvaga kwayo kwakakurumidza kuva mishonga inoshanda.

Muviri wakanyanyisa kubva mumuviri nemukaka uye zvimedu.

Zviratidzo zvekushandiswa

Mune zviitiko zvipi mycophenolate mofetil inoshandiswa? Mirayiridzo yekushandisa ichakurumidza kupindura mubvunzo uyu.

Vanachiremba vanoronga chirwere chekudzivirira kukanganiswa kwakasimba kwevarwere muvarwere shure kwepuro, chiropa kana kuchinja mwoyo.

Contraindications for use

Iko hakuna maitiro akawanda apo kushandiswa kwechirwere "Mofetil Mycophenolate" kunorambidzwa zvachose. Izvi zvinosanganisira murwere wehutachiona kune chinhu chikuru chakashanda kana zvimwe zvinoumba zvechirwere, uyewo panguva yekuzvitakura uye lactation.

Kubudirira uye kuchengeteka kwemishonga mukurapa kwevana kwakanga kusingazivikanwe, saka usashandise mukurapa.

Migumisiro Yechiri

Mofetil mycophenolate inogona kukanganisa maitiro emamwe matambudziko. Kushandiswa kwaro pamwe chete ne corticosteroids uye cyclosporine kunogona kukonzera chirwere, kurutsa, sepsis uye leukopenia. Mune zvimwe zviitiko, kukurudzirwa kwemakirini nemamwe zvirwere zvinouraya, kunyanya ganda.

Mukuwedzera, varwere vose vane mazai avo vari pangozi yekudzivirira zvirwere zvinotapukira, izvo zvakashungurudzwa nemakemikari ane mikana. Chinyanya kukosha pakati pavo ndeye herpes, candidiasis uye cytomegalovirus.

Zvimwe zvinopikisa zvinogona kuzviratidza pachavo sechimiro chechirwere, urinary tract infection, rhinopharyngitis, kuwedzera kwehutachiona, kusina simba kwechiropa chinoshanda, esophagitis, kubuda kwemimba, kuputika kwepamusoro maitiro, kukwezva, musoro, gastroenteritis, kuneta, sinusitis, oral candidiasis , Pancreatitis, pancytopenia, neuropathy nezvimwe zvakadaro.

Pane hutambudzi hwekuoma, uye pane dzimwe nguva kunyange zvinhu zvinokuvadza, zvakadai sechirwere chetachiona, bhakitiriya endocarditis, atypical mycobacterial infections.

Kusarudzwa uye Kutungamirirwa

Nzira yakarurama sei kushandisa mushonga we "Mofetil mycophenolate"? Dzidziso inowanikwa pairi inopa mashoko anotevera.

Nokudzivirira mafungiro etsvo. Nhamba yekutanga yezvinodhaka inofanira kuiswa mumuviri mukati maawa makumi mana nemaviri mushure mekugadzirwa. Mune ramangwana, murwere achada kutora 1 g yechirwere kaviri pazuva.

Mofetil mycophenolate inowanzotarisirwa pamwe chete ne corticosteroids uye cyclosporine.

Nokudzivirira kwekuramba mwoyo. Nhamba yekutanga yezvinodhaka inofanira kutorwa mushure memazuva mashanu mushure mekushanda. Munguva yemberi, chiyero chinodiwa chemishonga iyi 1.5 g kaviri zuva nezuva

Overdose

Dhiyabhorosi pamusoro pokudarika kwechirwere "Mofetil Mycophenolate" haisipo.

Haigoni kubviswa mumuviri ne hemodialysis. Zvinodhaka zvinosunga bile acids (cholestyramine), zvinogona kukurudzira kubuda kweFCC kubva mumuviri, kuwedzerwa kwayo.

Application Features

Kana murwere ane neuroepenia, zvakakosha kuderedza chirwere chechirwere uye kunyatsocherechedza hutano hwemurwere kana kukanganisa kurapa ne mycophenolate mofetil.

Muhupo hwekusava nekusakadza kwechirwere chisingaperi, iwe unofanira kunyatsotarisa hupenyu hwako uye usapfuure kuwandisa kwechirwere chechirwere, icho munyaya iyi chiri kusvika kusvika 2 g pazuva.

Varwere vekukwegura (kubvira makore makumi matanhatu nemashanu) vanokurudzirwa kushandisa 1 g yechirwere 2 kazuva.

Mashoko pamusoro pekubudirira kwechirwere mukurapa kwevarwere vane ruzivo rusina kukwana, avo vakatambura nechiropa kana kuchinja mwoyo, haipo. Hapanawo ruzivo rwekuti kubudirira kwemishonga iyi ndeyei kune varwere vane utachiona hwakakuvara uyo akawana chirwere chekupora mwoyo.

Precautions

Pasinei nechiitiko iwe unofanira kuzarura capsule nemishonga. Zvakakosha kudzivisa kusangana zvakananga nehupfu: inhalation, kusangana neganda kana mucous membrane. Kana izvi zvose zvikaitika, pakarepo unosuka nzvimbo dzakakanganiswa nesipo nemvura.

Analogs zvinoreva

Pane here mishonga inogona kutora mishonga iyi "Mofetil Mycophenolate"? Analogues, hongu, pane. Ivo vane imwechete INN (zita remarudzi ose risina kodzero) kana ATS-code. Chengetedzo yekuita kwemari uye kukosha kwayo ichasiyana zvikuru.

Inonyanya kuzivikanwa mishonga inotevera:

• "Baxmoon." Inoshandiswa mukubatanidza ne corticosteroids uye cyclosporine kudzivirira kurambwa kwemoyo, chiropa kana zvepvo mushure mokunge vashandurirwa.
• "Zenapax." Yakashandiswa kudzivisa kurambwa kwepimpidzo kupinza pamwe chete ne cyclosporine GCS.
• "Imusporin". Inoshandiswa mukudzivirira nekurapa kwezvikamu zvakashandurwa uye marora emapfupa, uyewo rhumumineid arthritis, endogenous uveitis, chirwere cheBehcet, systemic lupus erythematosus nezvimwe zvirwere.
• "Imufet". Kudai pamwe chete nemishonga inonyanya kukosha, iyo inogadziriswa inosanganiswa ne corticosteroids uye cyclosporine kudzivirira kurambwa kwechiropa chinenge chichitswa kana kuti itsvo.
• "Layfmun." Iyo mumiriri ane unhu hwakawanda hwekuita. Inogona kushandiswa kuchengetedza uye kubata chirongwa chekugadziriswa kwemuviri uye marora, pamwe chete neArthritis, nephrotic syndrome, maitiro anoshanda e systemic lupus erythematosus, chirwere chaBehcet, chinogumira kuveitis uye nezvimwe zvirwere.
• "Mifenaks." Zviratidzo zvekushandiswa zvakafanana neyezvinhu zvakasarudzwa.
• The Mifortic. Iyo yakagadzirirwa kuchengetedza kurambwa kweiyo mafungiro akaiswa.
• "Mosfilet". Chiratidzo uye nzira yekushandiswa yakafanana neyangu mycophenolate mofetil.
• "Panimun". Inoshandiswa pakugadziriswa kwemapapu, mwoyo, itsvo, bone marrow, pancreas, uye kune dzimwe zvirwere.
• "Sellsept." Inogona kunyoreswa kuti igove kupora.
• "Sertikan". Iyo inorayirwa zvepiyo kana mwoyo kupindurirwa mune varwere vane muongorori kana kuti pasi podzivirirwa kwema immunological.
• "Kudzora." Inoshandiswa mukubatana nemimwe mishonga yekugadzirwa kwechirwere.
• "Ecoral". Inoshandiswa pakugadzirisa zvipembenene zvemuviri, pamwe nekudzivirira kwekurambwa kwavo mushure mekutapurirwa.

Pasinei nokuti ivo vose vane nzira yakadaro, vasati vatora mushonga mukuru kune umwewo, unofanira kutanga watanga kubvunza uye kubvunza chiremba wako.