Myeloproliferative chirwere: zvinokonzera, zviratidzo, kuongorora chirwere

Myeloproliferative chirwere zvinokonzera, zviratidzo, chirwere izvo dzichakurukurwa Papera, vanoumba boka rinoti, kuzorwa nawo mumwongo pane ichiwedzerwa kugadzirwa thrombocytes, erythrocytes kana leukocytes. In zvachose mune mhando pathologies matanhatu.

tsananguro

Mwongo kazhinji anoita rudzi hunde (saibva) masero. Pashure nguva ivo vachiyaruka, izere. A hunde Sero kungava pokutangira kuti paumbwe nezvemarudzi maviri zvinhu: vanoverengeka lymphoid uye myeloid masero. masero saibva ndiyo mifananidzo kuti paumbwe leukocytes. Pakati pezvokuvamba myeloid akatevedzana anobudiswa:

• Erythrocytes. Vanotakura okisijeni nezvimwe zvinovaka muviri kwokubatana kune mapazi uye munyama.
• Leukocytes. zvinhu izvi ndiwo mutoro kupikiswa uye zvimwe zvirwere pathologies.
• Maplatelet. Masero aya kudzivirira ropa, chimiro clots.

Asati kushandurwa kupinda masero matsvuku eropa, chena ropa masero kana maplatelets, chokumisa masero vanoda kuenda mumatanho akawanda. Kana varipo, myeloproliferative chirwere, yakawanda kutanga zvinhu achiumbwa mumwe kana kupfuura mhando masero kuumbwa. Yemanyorero zvokurwara mberi zvishoma nezvishoma zvakakwana chete kuwedzera zvakawandisa zvinhu ropa.

kupatsanura

Type chingava myeloproliferative chirwere kunoenderana uwandu erythrocytes, maplatelet kana leukocytes. Mune zvimwe zviitiko, muviri nemuumbi zvinopfuura zvinhu zvinopfuura chimwe marudzi. Zvokurwara rakakamurwa:

• Chirwere neutrophilic neleukemia.
• Polycythemia.
• Chirwere myelogenous neleukemia.
• Essential thrombocytopenia.
• Idiopathic (chirwere) myelofibrosis.
• Eosinophilic neleukemia.

pathological Danho

Chirwere myeloproliferative inogona kuva rikwanise neleukemia. Izvi mamiriro ezvinhu ichazivikanwa noku nekumwisa ropa masero machena. Chirwere myeloproliferative chirwere ane inoshandiswa pakutsigira hapana chaicho zano. Kuchirapa matanho kuvimba mhando zvokurwara. Panyaya makwara, ari myeloproliferative chirwere munogona imwe zvitatu:

• Kumera mune dzimwe nzvimbo dzomuviri. Panyaya iyi, kenza rinopararira kuti dzakapoteredza zvikamu utano, kurova pavo.
• Lymphogenous nzira. Myeloproliferative chirwere anogona kupinda munzvimbo nhengo dzinobudisa maitiro uye midziyo yaro kuparadzirwa dzimwe nzvimbo dzomuviri uye nhengo.
• Hematogenous nzira. Masero malignancy kupinda munzvimbo capillaries uye mutsinga kuti zvokudya munyama uye zvomukati.

Kana kupararira nebundu masero, zvimwe wezvamatongerwe itsva (yechipiri) anomera. Izvi zvinonzi metastasis. Secondary kune chikuru namamota, ndizvo mhando kenza. Somuenzaniso, pane kupararira leukemic masero muuropi. It akawana bundu zvinhu. Ivo vanotaura neleukemia, kwete kenza uropi.

Zviratidzo zvokurwara

myeloproliferative chirwere sei? Zviratidzo zvinotevera zvirwere:

• uremu, neanorexia.
• Kuneta.
• Dumbu kusanzwa uye pfungwa zvokudya saturation. Last chagumbura rakawedzerwa chirwatata (splentomegaliey).
• Kubatwa kuti ropa, kupwanywa, kana zviratidzo thrombosis.
• Havachanyatsogoni kuziva.
• Kurwadza kwemajoini, kuzvimba, vakatsamwisa gouty chearthritis.
• Achirira munzeve.
• Soreness ari kuruboshwe yokumusoro quadrant pakati mudumbu uye rworuboshwe, inova migumisiro kuzvimba kana infarction yacho chirwatata.

tsvakurudzo

Myeloproliferative ropa nyonganyonga iri dzakaonekwa pahwaro mumarabhoritari zvabuda. The Ongororo zvinosanganisira zvinotevera mabasa:

• Kuongorora murwere. Panyaya iyi, nyanzvi inosarudza vakawanda mamiriro achiratidza zvokurwara (kuzvimba, somuenzaniso), uyewo anoratidza, pakanga pasina munhu utano. Chiremba anobvunzawo pamusoro murwere mararamiro, zvirwere uye tsika dzakaipa, akarayira.
• Extended KLA. Blood zvakabudiswa rinoitwa kuona:
  
  - uwandu maplatelet uye masero matsvuku;
  - reshiyo uye uwandu leukocytes;
  - padanho Chizenga;
  - vhoriyamu iyo inogarwa masero matsvuku eropa.

• Chido uye mwongo biopsy. Munguva nzira, gobvu mhango tsono kutaurwa kupinda sternum kana iliac pfupa. bata Izvi zvinobvumira kuti kutora mwongo yokuenzanisira uye zvinyama uyewo ropa. The acho anoongororwa nemaikorosikopu kuvapo kanganisika masero mairi.
• Cytogenetic ongororo. nzira iyi kunoita kuti rione kuchinja okutodza.

Chirwere myeloproliferative chirwere: Treatment

To musi, pane dzakawanda chirwere kurapa. Mumwe kana mamwe kuzvipedza anosarudzwa zvichienderana nemamiriro murwere uye kuratidzwa pematanho myeloproliferative chirwere. The kunokwanisa kupiwa mureza - nekusimba tsika, kana experimental. Kusarudza wechipiri kudzidza kushandisa siyana nzira itsva.

phlebotomy

nzira iri kutora ropa kubva tsinga. The acho ari ipapo wakatuma rwakafanana nokukanganisika kuongorora. Mune zvimwe zviitiko, phlebotomy ushandiswe varwere vari nechirwere myeloproliferative chirwere. Treatment muchiitiko ichi kuendeswa kuderedza erythrocytes.

platelet apheresis

Nzira Izvi zvakafanana yapfuura mumwe. Musiyano ndechokuti pane rinoitwa kubviswa mamwe maplatelet vachishandisa chinokosha michina. Murwere anotora ropa riri vakayambuka separator. Iye akabata maplatelet. "Yakanatswa" ropa shure kumurwere.

ropa

nzira uyu kuwedzerwa ropa. Panyaya iyi kuzvitsinhanisa dzimwe zvinhu. Kunyanya, murwere pachinzvimbo masero dzavo dzakaparadzwa uye kukuvaradzwa awana kuisira chena masero eropa, masero matsvuku eropa uye maplatelet.

mishonga

Nzira iyi inosanganisira kushandiswa cytotoxic zvinodhaka. Zvavakaita nechinangwa kuparadzwa bundu masero kana tava kuderera kukura anomera. For zvokuudzwa nomuromo, intravenous kana intramuscular kushanda zvinodhaka, avo unorapa kupinda munzvimbo systemic riparadzirwe, kubvisa pathological okunze. Izvi zvinonzi systemic mishonga. Regional chidobi ndiyo sumo zvinoreva kupinda musana canal, ari sei nhengo kana muviri mhango zvakananga.

nemwaranzi kurapa

Treatment rinoitwa kushandisa refu Frequency X-ray kana zvimwe kupisa. Radiation mushonga anogona kuzadzisa zvachose kuchaitwa bundu masero uye kuderedza kukura anomera. In tsika, mhando ane mbiri kurapwa. External nemwaranzi kurapa ndiye nokufumura ari Unit, yaiva pedyo kumurwere. Apo womukati zvekupfakira kwacho kuri kuitwa radioactive zvinhu tsono, catheters, sepombi, ayo zvino jekiseni zvakananga kupinda bundu kana kupinda munyama yaiva yakapoteredza. Inzira richashandiswa nyanzvi, zvichienderana mwero malignancy acho. Varwere vari chirwere myeloproliferative ropa nyonganyonga iri irradiated, somunhu ushe, chirwatata nzvimbo.

Mishonga pamwe transplantation masero

nzira iyi yokurapa ndiko kushanda zvinodhaka pamatunhu mishonga uye kuzvitsinhanisa sei antitumor chiito masero matsva. Saibva zvinhu zviri kubva anyatsoronga kana murwere uye nechando. Ndapedza mishonga, iri chakaunzwa muviri zvinhu zvakachengetwa. Zvakagadzirwa masero anotanga kukura uye zvinoita paumbwe masero matsva ropa.

kupora nguva

Mushure kurapwa, murwere vanofanira kuona chiremba wako nguva dzose. Kuongorora kubudirira mushonga kungadiwa kuitisa nhevedzano maitirwo kushandiswa kare pamberi kugadzwa. Maererano zvabuda, kusarudza kuenderera, kupera kana kuchinja kurapwa zvaiitwa. Vamwe kuongorora zvinofanira kudzokororwa nguva dzose, kunyange pashure pokupedza kuchirapa kosi. Vanobvumira kuti kuongorora kwaitwa nezviitiko uye kuona wava kusvutazve.