"Zaldiar": mirayiridzo kushandiswa. Reviews, mutengo, chigadzirwa tsananguro

Kurwadziwa ndeimwe zvisingafadzi zviitiko muupenyu hwomunhu. Vazhinji aripo zvinodhaka vanokwanisa kubvisa simba kana svikiro umbirimi marwadzo. Opioid analgesics, izvo zvinosanganisira rinoreva "Zaldiar" kunotaurwa munyaya ino, kunyange chinobatsira kubvisa chakakomba marwadzo anokonzerwa zvirwere zvakakura.

Pasinei nokuti mushonga haisi marwadzo, yaakazosunungurwa chete Pharmacies kubudikidza mushonga (fomu 148). Izvi imhaka yokuti zvimwe zvinoriumba zvaisanganisira kwaro sezvamunoita, kusanganisira nenyanzvi simba zvinhu. Mutengo nemishonga boka iri harigoni kunzi kuwanikwa vakawanda vatengi, riri ronga chipingamupinyi kupararira zvinodhaka. Asi tichataura pamusoro zvishoma gare gare, asi nekuda pakutanga patichanzwisisa chikamu pamahwendefa, chikuru ehupfumi waro unorapa uye zvakawanda.

Zvinoumba "Zaldiar" Mahwendefa

Chii chiri "Zaldiar" chinodhaka? Zvinoumba - ndizvo kukonzera iri kubudirira chero zvinodhaka. Mukuwedzera kuzivisa uye zvikuru kushandiswa paracetamol aripo mune mahwendefa ane mari 325 MG, "Zaldiar" unotora munhu fuma inozivikanwa tramadol hydrochloride (37.5 MG). Kana vatengi vanoziva paracetamol anenge kubva pauduku, kuti tramadol iri shoma kwazvo anozivikanwa vakwanise madenderedzwa. Uyezve, dzimwe nguva anoonekwa ari mushonga, kana chokwadi hazvisi. Kufanana zvose opioid analgesics chakaita zvokugadzirwa mavambo, tramadol anokwanisa kuita nenzira mbiri, rinogona kushandiswa kubvisa marwadzo yakakwirira uye unosvikirwa zvikuru. More mashoko pamusoro ichi ichakurukurwa chikamu pharmacological ehupfumi.

Kuwedzera kune basa yeimwe, kugadzirira "Zaldiar" unotora kutaridza ebetsero zvinoriumba: cellulose, sitachi, magnesium stearate, madhayi, uye vamwe vakawanda.

Description rekugadzirira, vasunungurwe chimiro

Yakabudiswa medicament muchimiro mapiritsi, enteric-zvemapuranga Kamudzira deko. Hwendefa chimiro iri oblong, rakatenderera, biconvex, zvemapuranga kudivi rakanyorwa "T5", uye kuno rumwe - the mugadziri wacho Logo "Gryunental". Mumuhara ruvara - chiedza tsvuku. Pakutanga kwezana mahwendefa anonyatsooneka kuoneka maviri akaturikidzana: wokunze uye yomukati yero - chena kana anenge chena.

"Zaldiar" Mahwendefa vari kugara munzvimbo Maronda akasiyana zvezvimedu 10, izvo anoiswa makatoni 1, 2, 3 kana 5 zvidimbu pamwe chete mirayiridzo kushandiswa.

Pharmacokinetics uye pharmacodynamics kuti "Zaldiar" chinodhaka

Kugadzirira zvinosanganisira maviri chete vanoshingaira zvinhu pamwe unonyaradza marwadzo maturo. Ndokusaka piritsi "Zaldiar" mirayiridzo kushandiswa rinoreva gadziriro yaisanganisa. Kuvhiringidzwa kurwadziwa nenjodzi iyi kunosvika akawanda mirayiridzo. Saka kubvisa kunyange marwadzo makuru.

Pharmacodynamics paracetamol ndiye deactivation kuti cyclooxygenase achirwadziwa uye kudziya uropi nzvimbo. Panyaya iyi, nefuma asingadi kukanganisa peripheral munyama, kureva kwavo prostaglandinsinteticheskie chaitika. Uyezve, paracetamol asingadi kukanganisa mvura uye electrolyte pakuenzanisa muviri.

Tramadol mabasa ari marwadzo nzvimbo yakati siyanei: nefuma wayo metabolites anokwanisa Activate anonzi M-opioid receptors. Rinotaurawo zvaanopa simba asiri opioid receptors kubudikidza Kamudzira hyperpolarization ari synapses pamusoro musana uye musana Tutsinga tunofambisa mashoko utwu. Pasinei zvakafanana. zviito tramadol ine fuma, rawo riri 6000 nguva shoma, akadai morphine.

Absorção de Água kuti paracetamol uye tramadol ari zvomudumbu turakiti kunoitika nokukurumidza zvakakwana. The Absorção de Água pamusoro paracetamol kwakakwana ndiko nokukurumidza zvikuru kudarika tramadol. Cleavage pakati Data ari unorapa kunoitika kunyanya chiropa. Ivo hwokurara ainyanya kuburikidza Urinary maitiro (30% kuchinja, vanenge 60% sezvo metabolites).

zvairatidza

The medicament "Zaldiar" mirayiridzo kushandiswa anokurudzira kuti panyaya svikiro uye simba kusimba kwokurwadziwa dzakasiyana mavambo (chirwere, kukuvara, kuzvimba, uye zvichingodaro. D.). Uyezve, Zvakakunakirai kushandisa ichi pakugadzirira risati kurapwa (chirwere uye dzokurapwa) kuti angaita marwadzo. Kutenga mushonga "Zaldiar" pasina mushonga, sezvataurwa pamusoro apa, hazvibviri. Ndokusaka kushandiswa kwayo inowanikwa chete muzviitiko apo zviri chaizvo.

Contraindications

Maererano nokushandiswa mahwendefa 'Zaldiar "mirayiridzo kushandiswa zvinoreva contraindications kuti inotaura hazvibviri kugashira chinodhaka, uyewo dzomuzana vake unorapa. Wokutanga uye kukosha contraindication anonzi idiosyncrasy wayo constituent zvinoriumba, kusanganisira adjuvants. Chimwe contraindication ndiyo murwere zera makore 14. Uyezve, pane zvakanaka zvakawanda pasi zvirwere uye mamiriro umo kutora mushonga hazvibviri nokuda ngozi yematambudziko siyana.

Saka, isu funga zviitiko apo mahwendefa vari contraindicated "Zaldiar" (analogs yezviri zvinhu uye harifaniri kushandiswa mune nyaya dziri pazasi):

• Zvipusha pfari hadzina aidzora yaunodya zvinodhaka chaiwo;
• zvirwere zvakakomba etsvo uye chiropa, zvikurukuru hepatic uye renal kukundikana;
• mamiriro pashure caffeine zvinodhaka, kana anonzi kurega chirwere;
• doro kana zvinodhaka kudhaka (kusanganisira zvinodhaka, nechepakati tsinga kuora mwoyo, hypnotics, analgesics uye zvimwe zvinodhaka).

The pamusoro inoti vanosungirwa kutevedza. Here'sa pamazita ezvinhu pasi iyo "Zaldiar" kushandiswa kwezvinodhaka zvinoda kungwarira uye kuramba zvichiongororwa murwere:

• kuvhundutsa, zvichiguma pakukuvara kana dzimwe nguva;
• craniocerebral kunotevera kunosiyana nekuomarara;
• yakawedzera intracranial kumanikidzwa (neBP);
• pfari, dzinodzorwa yaunodya mishonga;
• vanotaura kuti kufema basa;
• kuvhiringidzika kana kushaya Kujeka hana dzakasiyana mavambo;
• nemavhairasi chiropa zvirwere (chiropa);
• zvirwere biliary turakiti;
• Alcoholism pamwe chiropa chirwere kana kwete;
• kuvimba marwadzo zvinodhaka;
• hyperbilirubinemia (benign);
• epigastric kurwadza zvisingazivikanwi mavambo.

Mukuwedzera, zvinodhaka "Zaldiar" mirayiridzo kushandiswa yakarumbidza kutora nokungwarira vanhu vakura kupfuura makore 75, uyewo nevaya, kuwedzera mushonga, ushandiswe psychotropic nezvimwe unonyaradza marwadzo vamiririri vane anonzi nechepakati chiito (kusanganisira omunharaunda yokutindivadza ).

Kuti tidzivise vanyanye panjodzi murwere, chiremba anofanira asati varwere kuti mushonga kuti tiite kuferefeta zvose zvakafanira, iyo unogona kuziva chirwere ataurwa pamusoro.

Sei kutora zvinodhaka "Zaldiar": okuti

Drug "Zaldiar" unogamuchirwa chete pasi zvokurapa achitarisirwa. The chipimo chemushonga uye kwadzinoita kugamuchirwa nyanzvi anosarudza, inobva ezvinhu omurwere, ukuru kwokuomerwa marwadzo. Maererano kunenge vanachiremba, unofanira kutora mapiritsi rose pasina kupwanya uye pasina kutsenga. Huwandu mvura iro akageza pasi pamwe mishonga, zvinofanira kuva kwakakwana kuitira kuti apinda mudumbu asingadziviswi.

The kwokutanga dose kuti vakuru (anopfuura 14 years) ari pamahwendefa 1-2, zvichienderana nyanzvi zano. Zuva haisi varumbidzwa kushandisa kupfuura 8 mahwendefa "Zaldiar". Pakati nzira inofanira kuchengetwa panguva penguva maawa 6. Kana mumwe womuchato vamwe chikonzero akanga kurashikirwa, hapana chikonzero kushandisa chipo uye yapfuura zvinodhaka mishonga.

Varwere vakwegura (anopfuura 75 years), unogona kushandisa zvavaisiita dose zvinodhaka, asi zvinokosha kufunga kuti kubviswa yenhengo zvinodhaka uye metabolites vanhu vakadaro kwave nomumugwagwa kwaitora nguva pane zvimwe zera mapoka. Panyaya iyi, Zvinokurudzirwa kuti kuwedzera penguva pakati yemichato zvemahwendefa kuti maawa 10-12.

Itsvo uye chiropa kukundikana kunodawo kugadziridzwa kwadzinoita mabiko uye metering "Zaldiar" chinodhaka. Zvinofanira kucherechedzwa kuti anenge zvachose muviri panguva hemodialysis tramadol kushingaira chirungiso pamahwendefa. Saizvozvowo, varwere havachanyatsogoni itsvo basa tisatorera kudzokororwa mishonga dose pashure nzira iyi, sezvo zvingaita kuti ovhadhozi. mazano avo zvinogona kugadziriswa varwere vane zvakakomba havachanyatsogoni hepatic ushande. Panyaya iyi, mukana yematambudziko haubvi tramadol uye paracetamol kubva. Nengozi yematambudziko kunowedzera yekudyidzana mune vanhu vane chiropa yava kuchinja nokuda zvinokonzerwa doro.

The kukurukurirana pamusoro mushonga nedzimwe zvinodhaka

Kugadzirira "ratings Zaldiar 'izvo zvichaita kunzi hereinafter, anokwanisa kutaura zvinodhaka zvakawanda. Kwete nguva dzose kwakadaro mubatanidzwa kunobatsirawo pamusoro muviri murwere. Ndokusaka nyanzvi dzinokurudzira kuti vanhu vanotora mapiritsi aya, mushumo achitora mushonga kana vari basa zvimwe zvinodhaka.

Zvakakosha kuyeuka kuti Joint kugamuchira zvinodhaka "Zaldiar", mutengo izvo zvichashandiswa zvakaziviswa pamusoro, pamwe nemamwe zvinodhaka opioid rinobatanidza ngozi caffeine kubva makwikwi yezviri zvinhu chokuita marwadzo receptors. Kana zvakakodzera, izvi zvinodhaka Hour zvimwe zvinodhaka zvakafanana ehupfumi zvinofanira kuregwa.

Medicines kuti vamise basa CNS, izvo zvinosanganisira mapiritsi uye kurara mishonga nokuwedzera nemishonga hunhu "Zaldiar" Mahwendefa. Izvi zvinoshandawo doro-kwakavakirwa zvigadzirwa.

Vanoverengeka zvinodhaka, chikuru chinoratidza ndiro induction pamusoro microsomal oxidation, uyewo tricyclic antidepressants, barbiturates uye panyaya iyi, muderedze vanoshingaira zvinoriumba mahwendefa "Zaldiar" pamusoro marwadzo centre, razvo unonyaradza marwadzo mugumisiro ipfupi. Zvinoderedza uye nguva zvinodhaka chiito.

Kushandiswa kwose barbiturates pamwe zvinodhaka kunoderedza kubudirira paracetamol uye doro pamwe zvinogona kukonzera kukura rikwanise pfungwa nomuviri zvemwana asati ari muchimiro. Nonsteroidal mishonga Anti-anogumbura havasi varumbidzwa kutora pachiimbwa mahwendefa "Zaldiar" nokuda kwavo chaiyo kusakarongeka pamwe paracetamol. Chokwadi chokuti ichi zvikuru kunowedzera mukana renal kukundikana uye renal papillary necrosis zvivako. In Muzviitiko zvakaipisisa, murwere anogona kuva nekenza itsvo kana dundira.

With kushandiswa kwenguva yakareba pamusoro zvinodhaka "Zaldiar" kuwedzera zvainoita muviri kunyange duku DOX anticoagulants, zvichiguma yakawedzera mukana ropa.

nenjodzi

Pamahwandefa "Zaldiar" pane zvakawanda nemishonga kuti kukanganisa anenge zvose nhengo uye hurongwa. Kazhinji, varwere pazuva yokugamuchira mari yokutanga vatanga vavhiringe dzungu, kukwana kuyeuka, nokugwinha kana chakamira pakunodengenyeka zvine. Pakati nenjodzi yacho muviri kusvika pakugadzirira unyanzvi anotaurwa mananara zvakadai nehope kana kushaya hope, kuda kurutsa, flatulence, nomudumbu, uye mwoyo mwero. Kuwedzera pane zviri pamusoro apa, varwere vanogona kuona kumwedzi hadzina kufambiswa zvakanaka, kunonoka kana kusavapo weti, dyspnea, kupererwa neropa aplastichnaya.

Mazhinji kurapwa "Zaldiar" chinodhaka zvingamuka zvinodhaka nedoro kana ucharwadziwa pashure chimbichimbi kukundikana kutora pamahwendefa. Kuti izvi zvisaitike, haufaniri kutora mushonga uyu kwenguva yakareba kupfuura yakarumbidza mirayiridzo kushandiswa, uye abolition zvinodhaka inodiwa kubereka zvishoma nezvishoma zvinoderedza dose.

Zvokungwarira

Long chin'a kugamuchira kugadzirira ane tramadol kunogona kukonzera zvinodhaka nedoro, runoratidzwa kutya, psychomotor basa uye phobias. Panyaya iyi, nguva kurapwa "Zaldiar", ane mutengo wacho mukuru, zvakakodzera mukanyatsochengeta murayiro zvavakabvumirana ya kutarisirwa kwaro. Varwere vanenge ndamboramba ukama, vanofanira nemishonga pasi zvokurapa achitarisirwa.

Driving motokari kurapa zvigadziriswe zvakaoma uye munguva zvinodhaka kurapwa nani chemabhazi.

Drug analogues "Zaldiar": mitengo uye wongororo

Saka, kubva kumusoro, tinogona kugumisa kuti chinonyanya kukosha chii chinofanira kutungamirira mabiko "Zaldiar" chinodhaka, - nokurairirwa. Mahwendefa mutengo zvichienzaniswa nedzimwe mishonga simba sezvisipo refu kwazvo, uye anenge 800 rubles por rongedza. Analogs vane shoma kugadzirira: zviri zviviri vanoshingaira zvinoriumba vangazivikanwa kutoti pahwendefa "Forsodol", ane mutengo iri yepamusoro zvikuru. Pasina mubvunzo, mutengo mishonga kubva boka opioid analgesics havagoni kuva pasi, senzira "Zaldiar" ndiro risingadhuri pakati zvakafanana zvigadzirwa.

Maererano nezvokurara, mushonga uyu unobatsira kutsungirira marwadzo, kunyange zvakaoma chaizvo nyaya. Zvisinei, rinoratidza kuti kwenguva refu kana kusingadzoreki zvinodhaka kunokwanisa kukonzera kuti isingatarisirwi uye nemigumisiro yakaipa. Varwere vakashandisa zvinodhaka uyu vakaguta nebasa rake. Asi ivo akacherechedza kuti aro kubviswa inofanira zvishoma nezvishoma. Sezvo anopfuura 70% nyaya vane zviratidzo paiya inonzi kurega.