"Arimidex" - mirayiridzo yekushandisa nekuongororwa

Kenza yepabonde ndiyo yakanyanya kufanana nemhando dzakawanda dzemakumbo emukenza muhafu yevakadzi yevanhu. Kazhinji, chirwere ichi chinowanikwa mumudzimai wese wepfumbamwe ari pasi pemakore makumi mana nemashanu uye chegumi nemitatu - pazera remakumi mashanu nemashanu.

Kurapa kwakaoma nechokuti kenza inopararira kuburikidza nemuviri kuburikidza ne lymphatic system kuburikidza nekugadzirwa kwemasastases. Mukuvona kwokutanga kwechirwere ichi, kurapa kwakanaka nekuregererwa kunogona.

Asi zvinowanzoitika kuti mushure mekudzidzira mapoka echemotherapy, kushandiswa kwenguva refu kwemishonga inogadziriswa, zvinoitika kuti kurapwa kusina kusarudzwa. Mhando imwe neimwe yekenza ine zvirongwa zvayo zvekurapa zvichienderana nezera, pamwe chete nedzimwe chirwere chacho.

Kuti uone nzira yekurapa, kuongororwa kunoitwa, iyo huru iyo ndiyo cytology. Kunze kweizvi izvi zvinokwanisika kuwana mishonga yakakwana. Imwe yezvinetso zvakakosha mukusarudza kwemishonga ndeyekuti kune mikana yemigumisiro pamadzimai evanhukadzi, maziso, chiropa neitsvo, pamwe nemapfupa emapfupa.

Kuonekwa kwehomoni-inobva kune zvakasiyana-siyana zvekenza kunotungamirira mukurapa nehomoni inopikisana, imwe yeyo Arimidex.

Active substance

Makumi emakumi apfuura apfuura, murwere, paakagamuchira kusangana, akaenda kune homisi uye akatenga kana akarayira kubva kune muongorori mushonga waaida. Pasina mibvunzo uye kuzvidemba, ndakatora kurapa kwangu. Munguva yedu murwere anoda kuziva: chii chaanomwa? Ndezvipi zvimwe zvinetso zveutano zvinogona kusimuka?

Kuti usabvisa zvose zvinopesana, zvinokosha kuti udzidzise mirairo yemuiti weArimidx. Nhengo inoshandiswa yemishonga iyi anastrozole. Uyu mushanduki wemakemikari ndeyemakemikari anobva, izvo zvinovhara kubudiswa kweyero enzyme.

Aromatase inhengo inobatanidzwa mukushandura kwevarume vemadhemoni emukadzi (androgens) muhomoni dzevakadzi (estrogens). Kuwedzera kweeestrogen kunokurudzira kukura kwematumbu eesrogen.

Kuchengetedza estrogen uye kushandisa anastrozole pamushonga werapa we 1 mg pazuva. Kutora mishonga nguva dzose, varwere muzuva rokutanga vanochera huwandu hwemhomoni muropa ne 70%, uye zvino ne 84%.

Kushanda

Kana murwere achivimba nechiremba wake kurapa, haazoregi kutevera mirairo nemirairo. Kunyange kana vasina nguva dzose vakarurama. Chemotherapy kune vazhinji vagari vese kubudiswa kwe radioactive zvinhu kumasero epathogenic. Asi kunwisa zvinodhaka izvo zvinoderedza kukura kwavo mufomu yebhandireti zvakare chemotherapy.

Iro mirayiridzo ye "Arimidex" mahwendefa anotaura zvakajeka kuti anogona kungoshandiswa kugadzirisa chirwere chinowanzobatanidzwa (chinowanzo) chepachifu mumadzimai evanhu vanopinda mumasopaopausal. Inoshandiswawo sechinzvimbo chinodhaka chemishonga kuvakadzi avo vakambobatwa neTamoxifen kwemakore matatu.

Mukuwedzera, varwere vakapedza chikoro muchikamu chekutanga chekenza, zvakajeka kutevera mirayiridzo, kuongororwa "Arimidex" inogamuchira zvakanaka chete.

Dosage

Kuti zvive nyore kutamiswa kwemigumisiro yemishonga iyi, zvakakosha kuti tinyatsodzidza nzira yehutungamiri wayo. Anastrazole mudiki muyero we 1 mg haikwanisi kukonzera kukanganisika kwegorosi, uyewo kuwedzeredza basa reimwe nhengo uye zvirongwa.

Kutora mushonga wacho nyore nyore kugadzira, tora mapiritsi, ugeze pasi nemvura yakawanda. Kudya kwezuva nezuva kunofanira kuitika panguva imwechete, kuitira kuti kuiswa kwechirwere muropa hakusi.

Zvinodhaka zvinotarisirwa kuonekwa kwekenza masero, kazhinji kunwa kubva pamakore maviri kusvika mashanu. Chiremba anoenda kunofanirwa kuronga hurongwa hwekuedzwa huchabatsira kutarisa mamiriro ose ehurwere nekenza.

Zviratidzo

Makore maviri ekutsvakurudza mabhakato ave akaratidza kuti anastrozole, iyo iri chikamu che "Arimidex", inogona kushandiswa chete kune vakadzi munguva ye postmenopausal. Izvi zvinokonzerwa nekuti iyo nguva refu yekugamuchira inogona kukanganisa kusununguka.

Mhuka dzinoshandiswa panguva yekuedzwa, preimplantation kurasikirwa kweoocyte uye kuderedzwa kwenhamba yekubata pamuviri kwakachengeteka kwakaonekwa. Vana vakaberekwa vane zvisizvo zvakasiyana.

Kuti udzivise mibvunzo yakasiyana-siyana pamusoro pezviitiko zvakashata, zvigumisiro zvose zvakabatanidzwa mumirayiridzo ye "Arimidex". Zvose zviitiko zvinotambudza kune dzimwe nzvimbo zvakaonekwa nekuwedzera kwemazamu ezvokudya zvezuva nezuva (kubva pa25 kusvika 50 mg).

Migumisiro Yechiri

Mirayiridzo yekushandisa Armidex inoratidza zvose zvinogona kuitika zvinowanikwa muvakadzi vanozvipira munguva yekushandiswa kwemishonga. Chidzidzo chacho chaisanganisira zviuru makumi mashanu zvevanhu, vazhinji vavo vakabudirira kurapwa.

• Pakave nokuvhiringidzika mubasa rehutachiona hwehutano muhutano hwekuzvidya mwoyo, kuora mwoyo, kurara kana kusuruvara, kusangana kwemazuva kamwe, kushaya simba.
• Mwoyo mutsva: kuwedzerwa kweropa, dutu, kuora musoro, thromboembolism, thrombophlebitis, leukopenia, edema yemwoyo yemwoyo.
• Hemapiratori system: kubata kufema, zvirwere zvinopisa zvemapapu, huro nehuro (bronchitis, tracheobronchitis, laryngitis, rhinosinusitis, pharyngitis).
• Chirwere chepachiviri: chirwere, kusuruvara, kuvhiringidzika kwemukati (kuvimbiswa-chirwere), yakaoma muromo, pamusoro pematambudziko ematumbo, anorexia kana bulimia nehete yehuwandu hunorema inogoneka.
• Gynecology: kuoma uye kuchenesa mucous membrane, kutadza kubereka, basa rekuita ropa rinokonzerwa nokuchinja mumushonga.
• Musculoskeletal: inogona kudonha mapfupa emapfupa nokuda kwekushandisa kwenguva refu, chirwere chinonzi snapping finger syndrome.

Analogues

Mune mishonga yemaketani, zviri nyore kwazvo kuti urege kuwana mishonga yakadaro. Kune avo vakanyatsodzidza mirairo yekushandiswa kweArimidex, zvakafananidzwa pasi payo mumutengo, kuwana nyore nyore. Kunyangwe zvisingakoshi kutaura pamusoro pemutengo wakaderera, vanopikisa mahomoni, uye kunyange mukoti akanaka, nguva dzose inodhura.

Mifananidzo yakazara yebasa rinoshanda rinofanira kunge ine anastrozole mumuyero we1 mg. Muzvinyorwa zvekare kare CIS, kune dzakawanda dzakadaro, asi dzinoberekerwa munyika dzakasiyana, kazhinji ndiyo yeBaltic inotaura. Kunyange zvazvo kune madhiragi anobudiswa muIndia, Russia, Ukraine.

"Aksastrol"

Mishonga inobudiswa nefekitari yemishonga inonzi "Grindeks", Latvia. Iyo purafura ine mahwendefa makumi maviri nemasere mune firimu yefirimu, imwe neimwe ine 1 mg anastrozole.

Icho uchapupu hunoratidza kuti vanogona kurapwa nekenza yepamusoro yepamu mumadzimai emasopaopausal.

Kubva kunopesana -kuita uye pamuviri, pamwe chete nekunzwisisika kune anastrozole.

Mutengo wechirwere ichi paavhareji yeRussia ndeye 5-8 zviuru zveuru rubles, uye neUkraine - kubvira 1500 kusvika 1800 000 UAH.

Anastera

Mushonga uyu une anastrozole 1 mg, asi inobudiswa muArgentina. Kune mhando mbiri dzepakiti: yekutanga-mabhiriki maviri emapiritsi gumi nemana mune imwe neimwe; Yechipiri - nhatu mabhete emadhwendefa gumi mune imwe neimwe.

Iko boka rezvemasitoriki rinotsanangurwa sevadzivisi vehomoni, an enzyme inhibitor.

Zviratidzo zvinosanganisira, kunze kwekurapa kwe-estrogen-chinyorwa chekenza muvakadzi ve postmenopausal, mukana wekushandiswa kune varwere vane estrogen isina kunaka, asi avo vaimbova neruzivo rwakanaka naTamoxifen.

Anastrozole Sandoz

Yakabudiswa muGermany nekambani yezvokurapa Sandoz. Iyo purafura ine mabhiriki maviri ane mahwendefa makumi maviri nemasere. Nhamba, nzira yekugamuchira yakazara zvachose nemirairo yekushandiswa kwe "Arimidex".

Contraindications dzinosanganisira pamuviri, mukoti uye vana.

Mari yezvinodhaka iyi yakaderera kupfuura yepakutanga. Izvo zvakanakawo zvinoregererwa, asi zvinowanikwa nyore nyore kutenga.

Contraindications

Sezvatotaurwa pamusoro apa, maererano nemirairo, "Arimidex" haigone kushandiswa kuvakadzi panguva yekuzvitakura uye lactation.

Chimwe chezvinhu zvinokonzera kukwanisa kushandisa chiremba ndezvekuti munhu mumwe nomumwe anoregererwa. Vanhu vane hanya neaastrozole, pamwe neavo vari mubasa primusia, vachishandisa "Tamoxifen" kana esrogen mazano, "Arimidex" haigone kushandiswa.

Nekuchenjerera kana kusarudza zvinogona kushandiswa nevanhu vane hutachiona hwehutachiona, kuderera kwehutano hwakakwana, chirwere chemwoyo chinonzi ischemic.

Vakadzi vanotambura neasteoporosis, muitiro wekuchera uye kuora mapfupa mumirairo yemuiti "Arimidex" zvakajeka kuti chibvumirano chinokwanisika, asi nekuchenjerera zvikuru. Zvakakosha kutora miedzo kuti uongorore huwandu hwemapfupa emapfupa, uyewo kuwedzerwa kwekugadziriswa kwevamisiki nemavhitamini D. Muzvimwe zviitiko apo pane uwandu hwepamusoro hwekuderera kwehuwandu hwevanhu, zvinokwanisika kutungamirira bisphosphonates mukutanga kwekutanga kenza musati wasarudzwa naArimidx.

Dzimwe nzvimbo

Kuyemura kukuru kwemahomoni ekugadzirira kwemhando dzakasiyana-siyana vatambi. Ava ndivo vatambi vechikoro mumunda wekuvaka muviri uye powerlifting. Pamberi pemakwikwi, vanoenda mukana chaiwo wevanabolic steroid, vachivabvumira kuti vawane mafomu akanaka.

Kana iwe uchiyeuka, maererano nemirayiridzo yekushandiswa kwe "Arimidex", yakafanana nayo inoshandiswa kuderedza mahomoni evanhukadzi anobatanidzwa mukugadzirwa kwepabonde zvepabonde. Pakati pechirwere che steroid, vatambi vanoona kusuruvara kwezvipfuva, kunzwa kunorwadza, kubwinya.

Mukuwedzera kune zvigadzirwa zvakakosha, vatambi vanowanzoshandisa Arimidex mifananidzo, vachichitevera mirayiridzo, vachicherechedza mazoro ose uye nguva yekushandiswa.

Kuti udzivise "zvinhu zvinonakidza" zvehutano hwakasarudzwa, vatambi vanotanga kutora anastrazole pazuva regumi kubvira pakutanga kwechikoro nechisimba-acting steroids. Kunyange zvazvo iyi nzira isiri yepinecea uye inofanira kuitwa kunze kwekutarisirwa kwakasimba kwechiremba.

Ongororo

Kudya kwemishonga yemakemikari ndiko kunetseka kukuru kwomuviri. Zvose nhengo dzinotambura, uye muviri, usina kuwana zvinhu zvinodiwa, unoedza kubhadhara izvi nenzira dzakasiyana-siyana.

Mhedziso yechiremba nevarwere vakatarisana nemishonga "Arimidex" pane zvisinganzwisisiki. Nhamba yakawanda yevarwere vakagamuchira kusarudzwa kwe "Arimidex" mushure mekurapwa nemumwe mushori weestrogen - "Tamoxifen".

Chokutanga pane zvose, mari yezvinodhaka yakaonekwa. Paaita kugadzwa, nyanzvi dzakawanda dzinofunga kudzidza mirayiridzo yekushandiswa kweArimidx, kufanana uye kuongororwa kwevanhu vanenge vatoishandisa. Sei iri mubvunzo?

Mushonga wacho unotengeswa nemuti, nokuti vanorwara nekenza haina kupiwa pachena. Kuti uzvitenge, iwe unoda kubva kumabhiri zviuru masere pamwedzi. Haasi murwere wose achakwanisa kuzvitenga.

Asi mhinduro dzevarwere vakasarudza kushandiswa kwechirwere chinonzi anastrozole, chete chakanaka. Zviri nyore kutakura kupfuura Tamoxifen. Pasina kunhuwa kumuviri, uye zvinonyanya kukosha, hazvipi kuti zvive nemigumisiro yakadaro.

Mumwedzi yekutanga yekubvuma, zvichienderana nekutaridzika kune mumwe munhu, "Arimidex" inogona kupa kutyisa, kurutsa uye kushaya simba. Vaya vakanga vari kutora chemotherapy panguva iyoyo vaisagona kutaura nechivimbo kuti chii chaizvo ichi chakapiwa.

Pakati pese, kutora mahwendefa hazvisi zvayo. Varwere vakaedza kuchengetedza mari uye vakatenga mishonga yemishonga pamwe chete nemishonga yakafanana, vakanga vasina kufara. Akatambura zvakanyanya, uye zvinonyanya kukosha, chokumedza chokutanga chakanga chiri kurwadziwa kwakanyanya muzvibatanidzwa.

Mushonga wekusarudza?

Kune dambudziko guru nekuwana kurapwa kwemahara kune vakadzi vanoonekwa kuti vane kenza yemazamu. Pamusoro pemishonga isina kubhadhara varwere vezvipatara zvekugadzirira vanogona kuverenga chete "Tamoxifen", asi muumbi wepamba.

Ichi chinodhaka chakaoma kushivirira, kunyange zvazvo mitsva yakanaka. Tinoonga zviongororwa, mirayiridzo yekushandisa Arimidex, yakafanana nayo, unogona kusarudza kuti ndeipi yemishonga inofanira kutorwa.

Vanachiremba vanotaura kuti nguva yakanakisisa yekugamuchira Arimidex therapy inguva yemakore matatu kusvika mana mushure mokutanga kwemishonga naTamoxifen. Kazhinji kazhinji inogona kuonekwa semishonga yekurapa kwokutanga.

Ipa anastrozole kuvakadzi maererano nezviratidzo zvinokosha, apo imwe, zvinopesana nevanopikisa vane enzymes murwere asingakwanisi kutakura. Asi kwavari ivo mubvunzo wekuwanikwa kwemishonga inoramba yakasununguka. Mishonga inotakura inodhura zvinopfuura mari yepenjeni inowana. Uye mahwendefa makumi maviri nemasere mumapupa panzvimbo ye makumi matatu mugore rimwe chete anowedzera kune mamwe marara.

Kuti uite chisarudzo pakutora mishonga, zvinokosha kuti udzidze tsanangudzo ye "Arimidex" mumirayiridzo uye kuongororwa kwevarwere vakatozopedza chikoro. Zvichida vanogona kubatsira nechisarudzo: kubvuma kana kwete. Kunyangwe achitaura nezvemishonga inoshandiswa mukenza yemazamu sechirwere chekusarudza chakashata.

Mumwe nomumwe wevakadzi, mushure mekunge achinzwa kutambudzika kwakaipa, anotamburira hupenyu hwake uye hutano kune vekupedzisira, achishandisa nzira dzose dzinogona.