Diabetic Nephropathy

Zvimwe zvikonzero zvechirwere ndezvekusagadzikana kwehutachiona, nguva yakareba yechirwere cheshuga, dyslipidemia, arterial hypertension. Chirwere cheshuga nephropathy chinoratidzirwa nekuvhiringidzika kune zvinonzi glomerular zvishonga zveputsvo. Chirwere ichi chinowanzowanikwa mune varume uye vanhu vane chirwere cheshuga chekutanga chirwere chisati chava nemakore gumi nemashanu. Diabhesi nephropathy inowedzera mu30 muzana yevanhu vane chirwere cheshuga cheshuga.

Chirongwa chekuchirapa chekutanga chechirwere chinogona kuratidzirwa muhutachiona hwehutachiona. Chirwere cheshuga nephropathy mumashure ekuratidzwa chinoratidzwa mukukundikana kwetsvina uye nephrotic syndrome. Kuongorora vanhu vane chirwere cheshuga kunoda kuongorora kwegore negore ye nephropathy makore mashanu mushure mokutanga kwechirwere. Chidzidzo chegore negore pamusoro pechiratidzo chekusika chinodawo kuverenga GFR, ndiko kuti, glomerular filtration rate. Chirwere cheshuga nephropathy muzvikamu zvekutanga chinoratidzwa nekuwedzera kweGFR, iyo inopera nekukura kwekukundikana kwetsvina.

Nehropathy yeinso dzinosvika pakakwirira kwazvo mumakore 18-20 mushure mokutanga kwekutanga kwechirwere cheshuga mellitus. Uchapupu hwekusagadzikana kwehutano hwakadaro seyephropathy mu chirwere cheshuga mellitus is proteinuria. Anenge makore 10-12 mushure mokutanga kweproteinuria, uremia inokura, iyo inotungamirira kune imwe nyika yekusagadzikana kwepvo kusagadzikana.

Mamiriro makuru ekudzivirira kweephropathy ari kuchengetedza chirwere cheropa chemazuva ose nekubhadhara chirwere cheshuga. Inokurudzirwa kuderedza kudya kwezvokudya zvine mapuroteni. Varwere vanogoverwa kushandiswa kwe angiotensin receptor blockers uye ACE inhibitors. When
Arterial hypertension iyi mishonga inorayirwa muiyo hypotensive. Iyi mishonga inodzivirira kuchinja kwe microalbuminuria kuproteinuria. Mune zvimwe zviitiko, kurapwa kwakadaro, pamwe chete nekubhadharwa kwechirwere cheshuga, kunotungamirira kubviswa kwe microalbuminuria. Inokurudzirwa kunwa munyu hakusi kupfuura magiramu matatu pazuva.

Muchikamu chenguva isingaperi kusakundikana kwetsvina, kururamiswa kwehuga kupedza chirwere kunofanira kuitwa. Varwere vane chirwere chechirwere cheshuga mellitus vanoendeswa kune insulin therapy, sevanotora mahwendefa
Zvinogona kutungamirira mukukura kwehutano hwehyglycemia. Muhuwandu hwevarwere, kudiwa kwe insulin kunoderera, sezvo itsvo ndiyo nzvimbo huru yemasabolism.

Kuwedzera kwema creatinine kunomutsa mubvunzo wekuvhiya uye nzira dzechirwere dzokurapa. Nzira dzekuvhiya dzinosanganisira kufungidzirwa kweiyo, uye zvinopararira zvinoreva peritoneal dialysis uye hemodialysis.

Muchikamu chevarwere vane chirwere cheshuga cheshuga mellitus, pakuonekwa kweproteinuria, kufambiswa kwechirwere chisingaperi chisina kukwana kunoonekwa kwemakore gumi. Chirwere cheshuga nephropathy ndicho chinokonzera rufu rwevashandi ve15% nekuda kwekutsvaira kusagadzikana kusingaperi kwevanhu vasati vadarika makore makumi mashanu.

Kusvika iye zvino, nephropathy ndiyo iyo inokonzera rufu uye kukwegura kwakanyanya kwevarwere vane chirwere cheshuga mellitus. Kudzivirira kweNephropathy ndiko kudzora kweropa, apo maronda asingadariki 130/85. Zvakakosha kusiya zvachose kusvuta, sezvo nicotine inokonzera kukanganisa kwemukati mehuta yemasvingo emasera uye ine vasoconstrictive effect. Chimwe chinodiwa pakudzivirira chirwere cheshuga nephropathy ndiko kuchengetedza shuga muropa mumiganhu yakasununguka uye kugadziriswa kweropa. Pane chimwe chikamu chechirwere, chikafu chakakosha neproteiniti yega yega inopfuura 30% yezvokudya zvose inorayirwa.