Histidine: yemaitiro, nemakemikari

Mumwe nomumwe wedu kanenge kamwe muupenyu nezvazvo ake zvokudya. Pano, Somuenzaniso, chii nezuva ndozvakajairwa-siyana zvinhu zvinodiwa nomuviri kunouya kwatiri nezvokudya? Ndezvipi amino acids zvatinoda, uye nokuda chii? Nhasi, isu, Chokwadi, ngatirege kutaura kudya zvinovaka muviri wose, sezvo iri muduku uye kunyange gumi nevaviri nyaya. Tikaudza fuma rimwe chete, izvo zviri mubvunzo unokosha chaizvo kuti muviri. Izvi amino asidhi histidine. zita rayo makemikari rinonzwika kuoma - L-2-amino-3- (1h-imidazol-4-yl) propanoic acid. Asi zvinhu zvokutanga pakutanga.

Ndezvipi amino acids?

Tisati takurukura kuti zvivako zviri histidine wayo basa mumuviri, tichatema kunzwisisa pamwe rokuti "amino asidhi". Vaya aifarira mitambo, vakanzwa zvinhu izvi zvinhu. An amino asidhi chinhu makemikari remubatanidzwa rine dzichipfekeka mapoka inokosha maviri kuti kuti anokosha: asi amino boka -NH _2, uye kunonzi carboxyl boka -COOH.

The rokutanga anokonzera zvinhu ehupfumi dzeboka izvi zvisingatarisirwi yeimwe. Nokuda senitrogen uye ayo amino iine acid peya maerekitironi zvingaite chokwadi mhosva ions. Kana boka amino ari kutendeuka pano Ion yakadaro: -NH ₃ ^+.

The dzichipfekeka boka rechipiri anokonzera asidhi ehupfumi. It anokwanisa kupa hwepurotoni, achiva anion -COO ^-. Fani kwakadaro kunoita Anoumba munyu pamwe carboxyl divi boka.

Saka amino asidhi une zvikamu zviviri, chimwe nechimwe inokwanisa nokuumba munyu. Mumwe wavo anopa ehupfumi idzi yeimwe, acids, uye mumwe - nhandare. Kazhinji, kuti amino asidhi inogona achimiririrwa: NH ₂ -CH (R) -COOH. Tsamba R kunzwisiswa pano se "kukuru", i.e. chero makemikari PARTICIPLE raiumbwa dzichipfekeka mapoka uye carbon marangwanda uye vanokwanisa wezvamatongerwe chisungo (kana zvisungo) kuti substrate Morekuru amino acid.

Kazhinji, kunyange vaya vasiri kujairana pharmacology uye kwete kufarira zvemitambo, kamwe akanzwa, kanenge kubva kushambadzira, kuti amino acids zvatinoda, uye zvinobatsira chaizvo. Ngationei basa ravanoita mumuviri uye nei uchifanira kuwana navo kunodiwa mwero zvokudya.

Amino acids basa mumuviri

Sezvaunoziva, tose tiri rinoumbwa mapuroteni, kwemafuta uye makabhohaidhiretsi. Uye sezvo isu uvapedze sezvokudya kuramba chinhanho kwayo. Asi nyaya ino, tiri kuziva chete mapurotini. Ichi morekuru chikuru, kuita yakasiyana zvachose uye anokosha chaizvo mashandiro mumuviri wedu: chokufambisa ose zvinhu, kusikwa masero matsva, achisimbisa Links pakati muuropi Tutsinga tunofambisa mashoko utwu. tiri kutaura pamusoro kwete mapurotini. Chokwadi kuti zvose izvi zvinhu zviri inoumbwa amino acids, izvo zvingasanganisira histidine. Formula kunyange nyore mapuroteni unotora amino acids kanenge gumi, zvakabatanidzwa mune polypeptide cheni. Mumwe nomumwe wavo ane pachake nechivako rayo uye chimiro kuti unobvumira kuti aite mashandiro iro zvakanzi akasikwa zvisikwa.

histidine

The yemaitiro zvinosanganisira chero amino acid, sezvataona, mapoka zviviri chadzo uye kabhoni marangwanda, unobva pavo. Ndokusaka musiyano pakati ose amino acids (izvo, sezvinei, akatotanga akawana miriyoni shoma) ndiyo Kureba kabhoni zambuko pakati pemapoka maviri ari yakakura mamiriro, adjoint kwairi.

Musoro ino - ndeimwe amino acids - histidine. Formula iyi inokosha asidhi zvakaoma. Huru kabhoni cheni pakati pemapoka maviri dzichipfekeka tinoona mumwe chete kabhoni atomu. Kutaura zvazviri, zvinokosha proteinogenic zvose (inokwanisa rakasikwa mapuroteni) amino acids uyewo chete chete kabhoni atomu chuma. Uyezve, histidine ane zvakaoma kunzwisisa kukuru Zvichisanganisa yatinofema. Above unogona kuona kuti munhu histidine. The yemaitiro, ari STRUCTURAL kuchiitwa randinogara mune heterocycle (nechekuita mukugarisana zvimwe maatomu kunze kabhoni), zvamazvirokwazvo kwete chakaomesesa fuma.

Saka, kamwe takakurukura dzinokosha pfungwa, ngatiendei kune zvinoitwa kuti anogona kuitwa chete histidine pachavo.

mushonga ehupfumi

Zvaakazoita, zvinotora ichi amino acid, ndiye zvisinganyanyi kuitika. Uyezve siyana vane acids uye nezvigadziko, inopinda mukati biuret kumashoko kuumba zvigadzirwa mavara. Uyezve, histidine, ane nzira zvinosanganisira residues ose imidazole anogona vakaita pamwe sulphanilic asidhi muna Pauli kuita.

mhedziso

Zvichida vose mikuru zvinhu isu namambo mumwe chete dzakaparara. Tinovimba kuti nyaya kwaibatsira iwe ndikakupai zivo itsva.