"Metodzhekt": wongororo okuremadzwa arthritis, kunyanya kushanda uye kubudirira

Dzinonzi rheumatoid arthritis chirwere chiri chirwere danho. Hazvigoni murapwe asi unogona sipidhi kuchiita chirwere uye kudzivirira panowanikwa yematambudziko. Pakadaro, vari kubatwa immunosuppressants. Kune vaya chete ukama zvinodhaka "Metodzhekt". Reviews nokuti dzinonzi rheumatoid arthritis dzinoti kuti mushonga haaiti pakarepo, asi pashure 2-6 pemwedzi.

"Metodzhekt": sezvamunoita, Kuronga

It anogadzirwa mhinduro muchimiro nokuda Kutarisirwa injectable medicament "Metodzhekt". Reviews vane dzinonzi rheumatoid arthritis vanoti mushonga kana kushandiswa nguva dzose, zvishoma nezvishoma anobvisa kuzvimba mapfundo. Zvinobatsira kudzokera dzose upenyu.

Mishonga dzinobva yezviri chezvinonhuwira methotrexate disodium. zvinhu zviduku kwakadonhera mvura, uye yavaibvisa chloride uye hydroxide.

The mushonga anogadzirwa rakanamwa sirinji dzaizopiwa jekiseni. The sirinji kungava 7,5- 25 MG ose injectable mhinduro. Atorwa rine:

• girazi sirinji;
• epurasitiki kamwene;
• tsono rakazara rinokosha mhoni;
• kurayira Chinyorwa.

The Kugadzirisa ane pasherefu upenyu makore maviri. Yakabudiswa muGermany.

pharmacological ehupfumi

Rinoreva immunosuppressive uye mushonga antimetabolite "Metodzhekt" (mhinduro mune dzinonzi rheumatoid arthritis zvinoratidza kuti mushonga pashure kupinza kupinda mumuviri zvinogona kukonzera svoto uye dzungu). The mushonga kunoratidzwa Anti-bundu ehupfumi. Chinhu folate antagonist. Zvinoderedza dihydrofolate reductase, zvinotora chikamu vavakezve dihydrofolic asidhi kupinda tetrahydrofolic. The rinoita fuma pano anoshumira mutakuri kabhoni zvimedu zvinokosha kuti reunification ose purine nucleotides vavo nomukaka.

The mushonga kuchititadzisa DNA usage uye kugadziriswa. Kuchititadzisa muchitokisi mitosis. Methotrexate zvikuru chinobata bystroproliferiruyuschie masero chokuita mumwongo embryo rinenge nyanyisa namamota uye mucosal epithelium.

Zvinobudirira psoriatic uye dzinonzi rheumatoid arthritis. In kurapwa kwezvirwere izvi uye zvinodhaka Exhibits ane immunosuppressive Anti-anogumbura zvakasikwa. Mugumisiro mishonga nokuda kuwedzera adenosine kuwanda mu kushoma wongoramba.

zvairatidza

Reviews kuti "Metodzhekte" anoratidza kubudirira chezvinodhaka. Rinotaura kuti zvakanaka akashivirira uye kashoma kukonzera marwadzo.

Shandisa mushonga chete dzinonzi rheumatoid arthritis uye arthritis, yokupara chearthritis achabatsirwa zvakaoma chirwere uye kushingaira kukura.

Zvairatidza kuti majekiseni anoshumira psoriatic arthritis, uye generalized psoriasis. Mukupera mhosva, "Metodzhekt" rinoshandiswa kana mureza kurapa vakakundikana.

Contraindications pakushandisa

Rinotaura kuti zvakakwana anobatsira zvinodhaka "Metodzhekt" nokuti dzinonzi rheumatoid arthritis, wongororo. Haukwanisi kushandisa mushonga kana zvemamiriro chiropa basa, kushandisa spirituous zvinwiwa, renal kukundikana nenzira yakaoma padanho okukura.

Inofanira gadzai mushonga chete mwongo hypoplasia, zvikuru kupererwa neropa, leukopenia, uye thrombocytopenia. Hazvibviri baya jekiseni mu zvirwere pathologies akapfeka chirwere uye rikwanise. Haungopiwi mushonga kuti maronda maronda ari nomumukanwa mhango nemudumbu.

Havashandisi mushonga pavarwere vane zvakakomba Immune Deficiency, pamuviri uye lactating vakadzi. mushonga kurapwa haina kuitwa panguva imwe chete pokumuka yokudzivirira mhenyu. Contraindications pakushandisa vakashandisa constituent zvinhu hypersensitivity kuti medicament.

Shandisai mushonga nokungwarira vanofanira kuva vanhu vari kutambura ascites, nemudumbu mhingaidzo, kupera mvura mumuviri. Pasi pokudzora chiremba, unofanira kuva nemwoyo murefu pleural kana peritoneal effusion, uyewo vanhu vane itsvo kukundikana. With kutarisira mumiririri rinoshandiswa noutachiona, fungal, kwemabhakitiriya uye parasitic zvirwere. Also aisanganisira muri vanhu vanotambura nyore uye herpes zoster, gwirikwiti, huku pox varwere, varwere strongiloidozidom uye amebiasis.

Varwere vakura zera rokubereka pakurapa mishonga anofanira kushandisa pamuviri yakavimbika. Zvinofanira kuchengetedzwa yapera mishonga kwemwedzi mitanhatu. Kana mukadzi pamuviri panguva kurapwa, zvinokosha kufunga ngozi akaipa Migumisiro zvinodhaka riri azvarwa.

Methotrexate zvinoenda mukaka uye kunogona kuva nengozi kuti mwana. In pakurapa "Metodzhektom" ngaanyarare zamu zvokudya mwana wako panguva kurapwa.

Dosing

Raitongwa subcutaneously, nomutsinga uye intramuscularly zvinodhaka "Metodzhekt". Mirayiridzo dzokushandisa uye inofambiswa inokurudzirwa kushandisa mushonga kamwe pavhiki, panguva imwe chete. Duration kurapwa anodzora chiremba.

Vakuru vane mishonga dzinonzi rheumatoid arthritis ushandiswe kuti 7.5 d kamwe pavhiki. The nzira chourongwa angava ani. Zvinofanira kutanga rakadzika dose. Kana zvakanaka kuzoregwa murwere, kuti chipimo chemushonga iri zvishoma nezvishoma yakawedzera 2,5 MG pavhiki. Vhiki kunonyanyisa zvazvingava akaenzana 25 MG.

Mugumisiro inoonekwa mushure memasvondo 4-8 kurapwa kudzidziswa. Kamwe akakwanisa kubvisa zviratidzo hosha, kuti dose iri zvishoma nezvishoma wakaderedzwa kushoma. The kuchirapa nzira inogona kugara makore gumi kana kupfuura.

In kurapwa kuti psoriatic chearthritis uye psoriasis vhiki pamberi mharuro yokurapa yakarumbidza yokusuma bvunzo dose pamusoro 5.10 MG mhinduro kuti vasabatwa kuti nemishonga.

Kana paine mirayiridzo hapana mumwe chiremba wacho, unofanira kutanga pamwe 7.5 MG kamwe pavhiki. The chipimo chemushonga iri kuwedzera zvishoma nezvishoma. Hazvifaniri kupiwa vhiki pamusoro 25 MG kuti mhinduro. Maximum bvumidzwa dose yevhiki nevhiki MG 30 psoriasis. Mugumisiro inoonekwa mushure memasvondo 2-6. Awana zvinozoita kuti chipimo chemushonga ipfupi.

Vanhu vane itsvo uye chiropa kukundikana, uyewo vakwegura zvinodhaka anofanira kushandiswa nokungwaririra.

Vana vari pasi pemakore gumi nechirwere yokupara chearthritis anofanira kutora mushonga pa mwero 10-15 MG / m ² muviri pemvura. The dose anogona ngazviwedzerwe vaifanira mu mureza 20 MG / m ^2. Vana vanokurudzirwa zvinodhaka raitongwa intramuscularly.

Kudzivisa marwadzo, vanachiremba akarayira rakatevera jekiseni folic iine acid supplementation, pamusoro pamazuva mashanu anotevera. Vasati jekiseni, uye pazuva paumbwe vhitamini B9 havagoni kunwa zvinodhaka.

Zvinodhaka ndozvinoitawo

Kana "Metodzhekt" haana kuuya kunorapwa, chiremba anogona kutsiva mushonga mumwe, zvakafanana akafanana uye ayo chiito. By zvakafanana analogs "Metodzhekta" anosanganisira:

• "Vero Methotrexate."
• "Zeksat".
• "Metortrit".
• "Methotrexate".
• "Methotrexate-din email".
• "Treksan".
• "Triksilem".
• "Evetreks".

Izvi uye zvimwe analogs anogona kutsiva nyore chinodhaka, asi vanofanira kusarudzwa nenzira kupinda chiremba.

mari

Nyatsoteerera kwemitengo yezvinhu "Metodzhekt" chinodhaka wongororo. In dzinonzi rheumatoid arthritis (mutengo mushonga uyu kumativi 600-750 rubles por 0.75-1 Rine mamiririta, nokuti 800-1400 rubles, unogona kutenga 1.5 kusvika 2.5 ml kugadzirira) havasi kunyanya kusarudza. The chirwere kunoda yevanorwara zvikuru. Izvo, zvinosuwisa, inodhura kwazvo.

Rinonyevera kuti aifanira kupinda nevhiki rinoreva "Metodzhekt" mirayiridzo Chinyorwa. Reviews (mutengo pamusoro zvinhu dzingasiyana zvichienderana chemishonga pfungwa) inoratidza kuti zvinodhaka mutengo zvakakwirira chaizvo, asi pasinei neizvi, mushonga anopa Somugumisiro akanaka.

Kubudirira mushonga

Cherechedza kuti anoita upenyu chaihwo mukurwisa dzinonzi rheumatoid arthritis zvinodhaka "Metodzhekt" wongororo. Kunyatsoshanda rinoreva akaratidza vanhu vakawanda.

Kubayiwawo jekiseni chinodhaka anobvumira mushonga woga zvakananga kupinda muropa, pavaigona kutora chikepe chaienda mudumbu uye ura. muenzaniso uyu kushandiswa kunopa kunyatsoshanda kupfuura nemishonga nemumuromo.

"Metodzhekt" pahwaro methotrexate rinoreva zvinhu kunatsiridza antirheumatic nevamiririri. Rine simba Anti-anogumbura ehupfumi. Inogona kupiwa mumatanho akasiyana-siyana dzinonzi rheumatoid arthritis. Zvinochinja weboka chirwere. Kushandiswa nokurwadziwa, kuomarara, uye kuzvimba majoini.

The mushonga ari kubatsira vanhu vakawanda kuti kurarama upenyu, chengeta kushanda. It DZEMUNHU DZINODZORA kuchiita chirwere kwacho uye kukuvara articular shwashwa uye tishu. The mugumisiro kwokubatsira mushonga kwakacherechedzwa pashure pemwedzi mitanhatu.

Reviews vanachiremba

Kakawanda, nokuti pakurapa dzinonzi rheumatoid arthritis, chiremba waakaudzwa "Metodzhekt". Reviews vanachiremba vanoti kazhinji kunokonzera nemishonga uye zvakanaka akashivirira nevarwere. It anonzi imwe yakanakisisa immunosuppressant. Inogona kushandiswa kuramba utano dzose nguva, kwemakore akawanda.

The mushonga chepfu, uye naizvozvo, kana kushandiswa, vanachiremba zano kuchengeta dunhu chourongwa uye dose. Wedzerai kana kuderedza uwandu husingakuvadzi zvishoma chete pasi zvokurapa achitarisirwa. Izvi zvichaita kuti zvinobvira matambudziko. Vakadzi vose achirapwa kurapwa ne "Metodzhekt", vanachiremba vanoti kushandiswa pamuviri yakavimbika senzira anogona kukanganisa azvarwa.

Reviews dzokushandisa vana

chete pamusoro mishonga inonyorwa inofanira kushandiswa "Metodzhekt". Reviews nokuti RA chearthritis mune vana kutaura pamusoro zvakanaka mugumisiro, aunopiwa mushonga. In vana, izvozvo chinotarisirwa muna 2 Rine mamiririta kamwe pavhiki. Vamwe varume vane kare vaiva nedambudziko majoini pashure majekiseni dzinotanga kumhanya, kuwedzera basa. Vanotarisira kuti vabudirire-refu kuregererwa chirwere uye kumboderera.

Kids uyo vaaknga "Metodzhektom" Havasi zvakasiyana nevezera ravo. Vatambe zvakawanda, uye kurwadziwa majoini kurega vanetseke. Vane zvishoma kuzvimba makumbo nemaoko, zviziso zvemakumbo. Improvement hakuitiki pakarepo, uye pashure 3-4 jekiseni.
Vamwe vanaamai vanoti kana ukaita majekiseni pamberi zvokudya, muve svoto uye dzungu. Mishonga pashure zvokudya riri nani akashivirira navana. Pasinei kubudirira chinodhaka, hazvina kupa 100% kupora.

Medicine "Metodzhekt": wongororo mune dzinonzi rheumatoid arthritis

Maonero pamusoro gadziriro ino rinoumbwa kunyanya akanaka. Varwere vanoti pomutumwa kunodzivisa kukura chirwere, asi, kana rikashandiswa ichengetwe vanofanira pasi zvokurapa achitarisirwa.

Medicine anobvisa kuzvimba, anobatsira marwadzo, asi kwete marwadzo ose anoenda zvachose. Vamwe vanomanikidzwa kutora mamwe analgesics. The mushonga anoramba chaizvoizvo kwevhiki, uye kana nguva hakuiti kuti bara, zviratidzo chirwere zvingaitika zvakare. Varwere wazorodzwa mushure 5th jekiseni.

Kune vanhu vane dose rutapudzo uye kubviswa pakati zvinodhaka akakonzera inokanganisa. Ivo kwakaratidzwa muchimiro chirwere, marwadzo, dzungu uye svoto. Vanhu ava vakaona kuti dose anofanira akaderedzwa zvishoma nezvishoma uye chete pashure kuwana kuregererwa kwakakwana.

Varwere More chokunyunyuta pamusoro ndechokuti mushonga zvakaoma kuwana Pharmacies uye zvinofanira zvikuru akarayira. Vakawanda havana inogutswa mukuru mutengo zvinodhaka. Vanoona kuti varwere hosha yemajoini mishonga RA inofanira rakapa pachena, sezvo asina wose anogona kutenga nayo.

Kazhinji, nokuti mishonga chakakomba zvirwere mapfundo rimwe zvinodhaka kupfuura simba uye ano ndiyo "Metodzhekt". Reviews (pamwe dzinonzi rheumatoid arthritis muvana uye vakuru, izvi kunyanya kukosha) nharo kuti rinovatadzisa kukura chirwere uye kunobatsira kuti vabudirire-refu kanganwiro.