Professor Skulachev: ziso anodonhedza. Eye anosiya "Vizomitin" (anosiya Skulachev) wongororo, mutengo, mutungamiriri

Time haamiri vachiri, uye zvose zvipenyu upenyu siyana Panyika inozviisa vakwegura kuchinja. Emerging kuchembera pezvakaitwa kuona chimiro kusagutsikana pachavo Muviri nevamwe, panowanikwa inofamba panguva nokukurumidza kufema, dyspnea, akakotama mamiriro uye miganhu kufamba. Uyezve, chiratidzo kuipa.

Kune pfungwa, izvo, sezvinei, zvakajairika chaizvo kuti vasachembera hachisi chinhu kuti kurega, uye kuderera kutonetsa. Professor Skulachev, ziso anodonhedza izvo zvechokwadi chishamiso zvazviri, inoomerera dzimwe pfungwa.

Chokwadi, kukwegura - chinhu dzinongoitika chichiitwa, asi nokuda kwechikonzero harigoni kumboderera? Kuchembera haisi pasina chikonzero. In mudenderedzwa masayendisiti zvinobatanidzwa vasachembera womunhu muviri, pane simba pfungwa kuti yedu DNA cheni hwakanyorwa purogiramu inokosha kuti ndiye anokonzera vasachembera mumuviri. Paaizosvika rimwe zera, pane activation chepurogiramu, iyo pakupedzisira inotungamirira zvisingadzivisiki - rufu.

Chii ngozi vakwegura maziso

Kutyora dzinotsanagura kuona maonero mumwe zvinoratidza kuchembera. Kwete, Chokwadi, unogona kusangana nevanhu guru ezvinhu utano, riri kukwana kuti kupikiswa vanoshingaira uye dzakazara ose zvirwere wachembera, asi kana munhu pakarepo kurasikirwa chiratidzo, kana zvichaita kuderera zvinoshamisa, kunyange "gamba" akadaro anova vakatongerwa vakaremara.

Ruzhinji rwakapindura zvirwere ziso kuva pamusoro nguva zvishoma nezvishoma. With zera, kuti lacrimal shwanu ari kushanda zvishoma, uye izvi zvinosanganisira vasanyanye pakuburitswa uye unhu misodzi. It anova kuoneka pashure richisvika nemakore 40, asi kunogona kuitika uye pashure 30.

Kufanana, chii ichi? Ndezvomuzvarirwo kuti nezera kunova wakawondereiko kudai mazuva ose unodzivirira ziso plyonochku kuwedzera kuitika corneal microtrauma uye kukuvadza, anogumbura zvirwere, nokukurumidza eyestrain. Zvimwe microchanges dzakadaro ndidzo nheyo kukura zvakawanda zvinouraya zvirwere zvakadai cataract, vakawedzera intraocular kumanikidzwa pamwe kukura yemaziso, angatanga chinopedza kuchinja ari the retina uye optic tsinga kubva mberi kurasikirwa zvaakaratidzwa. Asi regai kutya kuti zvirwere izvi zvingaitika, uye zvose mune jiffy. budiriro yavo anononoka uye zvishoma nezvishoma.

Izvi akasunda ndechokuti muzvinafundo vakasarudza kusika Skulachev ziso madonhwe. Anodzokorora kuti kudanana navo akanaka chaizvo. A guru kwazvo, kana asina mukuru, nhamba varwere ophthalmic kuwana mukana zvakare ine zvakajeka takangwaririra Kutarira nyika pasina kuvhiyiwa. Uye nemhaka kuti afunga Professor Skulachev ziso madonhwe, mutengo chiri kupfuura democratic.

Antioxidants akadai mitochondrial

Muna Moscow State University. University kubva 2005, iye akatanga kuongorora chirongwa pamusoro pokumuka zvinodhaka zvakagadzirirwa kunonotsa activation purogiramu uye sipidhi vasachembera. Achitungamirirwa V. P. Skulacheva, Academician of Russian Academy of Sciences, zvipenyu musayendisiti uyo kwemakore anopfuura makumi mana mubasa tsvakurudzo pamusoro pezvakaitwa kuitika mitochondria, yagadzirwa itsva mhando unorapa - antioxidants mitochondrial mhando.

Kuburikidza kudzidza pashure nokugadzirwa kwakaitwa ichi mhando makemikari pakutanga, masayendisiti akawana kuti mitochondrial antioxidants kufambira, uye mune zvimwe zviitiko rakachinja dzinotsanagura ophthalmic nezvirwere mhuka kuedza. yakawanda basa nokugadzirwa mishonga mitsva kwakavakirwa mitochondrial antioxidants zvaitwa makore mashomanana gare gare, uye Professor Skulachev ziso Madonhwe nezvevanakomana pasi zita "Vizomitin".

Ngatitarisei rimwe zviratidzo kuchembera ziso rokutanga - zera-chokuita dysfunction pakati ari lacrimal shwanu. Chii chinoitika nezera? With zera pane kuderera pakati quantitative uye Qualitative zvechadenga lacrimal mvura uye, naizvozvo, kukura urwere pakati "maziso akaoma". It kunoratidzwa kutanga kunzwa kusagadzikana mumaziso, kunzwa jecha kana duku vatorwa muviri, uye zvishoma nezvishoma kunoita chirwere vanogona zvakawanda zvakakomba.

Cherechedza kuti sedonhwe tsanga pari zviripo mishonga pamusika vazhinji. Uyewo guru uye uwandu zvinodhaka zvainanga pakurapa symptomatic kuratidzwa panguva "ziso rakaoma", asi zvinenge zvose (kana ruzhinji) chinhu chakaita zvokugadzirwa analogue evanhu misodzi Urume. chikuru chinetso chavo ndechokuti murwere ane kushandisa zvinodhaka izvi kubvira nguva 10 kusvika 20-25 rimwe zuva, kubva pakushandisa chete zvainanga kudzorera chakaipa misodzi Urume tigutsikane muziso.

Laboratory uye zvekuchipatara miedzo

Ichangobva donhwe "Vizomitin" akasiyana vangasimudzira kubva nheyo kushanda zvakafanana mishonga inoshandiswa kurapa yeziso rakaoma. Ndivo chikonzero chaiwo chirwere, kuwedzera kushanda lacrimal shwanu uye kumisa kuchinja varo chinopedza. Uyezve, pfapfaidzo mumate kunodarowo sezvo mumate ose cataract yakavakirwa chakagadzirwa misodzi.

ezvinhu ichi - haisi yokungotaura mashoko, asi chaizvoizvo yakasimbiswa chokwadi. Professor Skulachev ziso anodonhedza akaongorora zvakasimba mune mhuka uye miedzo zvekuchipatara zvinodhaka rakaitirwa zhinji nzvimbo ziso: panguva weDhipatimendi Ophthalmology (Russian State Medical University) uye panguva Research Institute of Eye Diseases Helmholtz.

Migumisiro vakawana muzvidzidzo izvi uye miedzo kurapwa, migumisiro yacho inokurudzira zvikuru. Professor Skulachev, ziso madonhwe, izvo kutengeswa pasi zita "Vizomitin", anoti vari zvikuru kunobatsira kupfuura mishonga yakafanana inoshandiswa kurapa uye kubviswa nezviratidzo urwere pakati "ziso rakaoma". Uyezve, zvinofanira kucherechedzwa kuti kurutivi migumisiro panguva kurapwa pamwe samadonhwe idzi varwere vakanga kuchengetwa.

Zvichienderana migumisiro zvidzidzo izvi, mushonga rakanyoreswa muushumiri Health uye Social Development muna December 2011 senzira keratoprotektornogo rinonzi "Vizomitin", kana ziso anodonhedza Skulachev. Where kutenga mishonga nhasi? Sezvo muzhizha ra2012, wakazviratidza munyika chitoro rezvebonde Pharmacies.

Zvechokwadi, kufanana nezvimwe zvinodhaka chero itsva kare anozivikanwa rinoita fuma "Vizomitin" yakabudiswa chete mushonga. Ndinogona kutenga pasina ziso anodonhedza Skulachev? Where kutenga kwavari, kana kwete resipi? Haapari mazano, uye kubata kwenyu kupinda ophthalmologist. Vacation zvinodhaka mushonga haumanikidzwi kureva zvikanganiso - nayo zvikuru anosarudza chinangwa chawo Vanosarudzwa, izvo zvinozoita zvinoreva zvinobatsirawo kushanda.

A nedzimwe zvechokwadi Kuwanika chakaitwa Professor Skulachev. Eye anosiya, izvo akaongororazve chete kusangana zvakanaka zvechokwadi vane zvinoshamisa nomugumisiro. Nokuti Implementation dzavo uye kurapwa zveBhaibheri vanofanira kuva nemi kwete chete kuRussia asiwo munyika yose. chinodhaka ichi nyaya yoga Misangano uye okudhindira kuunza mashoko ose ophthalmologist.

Ngatikurukurei kugara zvakadzama yakawanda "Vizomitin" gadziriro. Mirayiridzo dzokushandisa kunogona kupa zvakawanda dzinonakidza.

Description rekugadzirira

Iyi nzira iri substantially segirazi zvichida mavara zvishoma kana zvishoma opalescent zvokunwa. Plastohinonildetsiltrifenilfosfoniya rinoita fuma iri bromide, izvo 1 ml kugadzirira rine 0,155 micrograms. Sezvo Excipients inoshandiswa benzalkonium chloride, hypromellose, yavaibvisa chloride uye nevamwe. Mushonga uyu ndohwaJehovha kuboka keratoprotektornyh pharmacotherapeutic vamiririri, uyewo boka antioxidants.

Data pamusoro pharmacodynamics

Plastohinonildetsiltrifenilfosfoniya bromide remubatanidzwa rinobva plastoquinone iyo kuburikidza rinonzi saka linker cheni chokuita residual triphenylphosphine. Sezvo Dr Skulachev akati ziso anodonhedza (nomutengo wavo nokuda hama cheapness pamusoro kwetunhu mukomboni ino haisi yakakwirira) pa nanomolar kuwanda vanokwanisa nedzokunze refu kwazvo antioxidant basa dzakakwirira nekurukurirano zvazvinoita slezoobrazovaniya pezvakaitwa kuwedzera mumuviri pakusimba inoumbwa misodzi firimu uye zvine zvazvinoita epitealizatsii kwendangariro.

pharmacokinetic date

To musi, zvinofanira kutaurwa kuti vanoverengeka pharmacokinetic zveBhaibheri vasina inoitwa nevanhu. Panyaya pre-zvekuchipatara zvidzidzo mhuka, kuparadzira basa fuma mumate vari nhengo yaiitwa nokuda 2 mazuva pashure nemukanwa kana parenteral yaitonga. Kuvapo bromide plastohinonildetsiltrifenilfosfoniya kunyoreswa dzokumusorosoro kuwanda mu renal zvinyama uye chiropa rinenge mwoyo pashure 1 awa pashure kutarisira. Zvakanga akacherechedza kuti nefuma nokukurumidza pasi disintegration vachishandisa makemikari uye akaratidza vaikwanisa covalent kusungwa pamwe mapurotini.

Zvairatidza uye contraindications

Anosiya Skulachev "Vizomitin" vakagadzwa vari urwere pakati "ziso rakaoma", zera zvine kuchinja zviri lacrimal shwanu, kombiyuta syndrome. Zvichienderana kuti kwesainzi kupinda migumisiro zvinodhaka vachiri kuramba, zviri pachii cataract, yemaziso uye kunzwisisa kurapwa chero chirwere muna ophthalmology.

Sezvo Skulachev Vladimir akataura, Madonhwe ziso vari contraindicated pakuparwa hypersensitivity kuti mushonga, uyewo vana pasi makore 18.

Kushandiswa pamuviri uye paanenge achiyamwa

To musi, renguva randomized, mapofu, vaidzora zvidzidzo zvinodhaka vakadzi vane pamuviri, uyewo akanga kuitwa ekukurerai. Tichifunga ezvinhu ichi, hazvina yakarumbidza kushandiswa kwezvinodhaka panguva gestation. Kana paine kushayiwa kugadzwa zviri lactation nguva, uchiyamwisa anofanira vakarega.

The nzira chikumbiro uye chipimo chemushonga

The mushonga anofanira kwakarovererwa 1-2 madonhwe kupinda pakati conjunctival zai kuti murwere ziso katatu pazuva. Zvichienderana kwokuomerwa zviratidzo uye kwokuomerwa nguva yose kuchirapa weboka chirwere chinogona kuisa nomumwe kurapa ophthalmologist.

Marwadzo uye ovhadhozi

Maererano nokutsvakurudza, uyewo kurapwa uye rabhoritari kuidzwa zvinodhaka, marwadzo vave kuzivikanwa, asi anogona kuva nokuratidzwa neutachiona. Data ovhadhozi kubudikidza kukamura uchishandisa pokushandisa zvinodhaka iripo.

Drug kwavatori

Data zvinodhaka aiita zvimwe zvinodhaka vane mapoka. Kana paine chikonzero mawa kushanda "Vizomitina" nevamwe Madonhwe ziso, ziso instillation musiyano pakati zvinofanira kuva kwemaminitsi 5.

Zvokungwarira

Mumiedzo zvekuchipatara zvinodhaka zvabuda avapo, kuti "Vizomitin" anokwanisa kukonzera pfupi-rokuti pekugara vachivavhiringidza, zvichiteverwa kwayo rutapudzo. Kana mushure kwokubatsira zvinodhaka riri kuchengetwa ziso vachivavhiringidza, haafaniri kubva motokari kana kudzora zvenhengo uyewo Implementation zvinhu zvinoda kugadziriswa, kusvikira zvizere kuzoita kutarisana acuity.

kusunungurwa Form

Ziso anodonhedza pamwe chinoshingaira chirungiso zviri 0,155 ug / Rine mamiririta anobudiswa mune chaiyo hombodo dzemvura polyethylene 5 Rine mamiririta inzwi kuparidzirwa - droppers uye sikuruwa chivharo. The mushonga asunungurwa chete mushonga. Chengeta ziso inodonha ari zvakafanira panguva tembiricha inobva 2 kusvika 8 ⁰ C.

Where kutenga zvinodhaka

Buy anosiya "Vizomitin" vane mutengo nhasi haasi mukuru, kana iwe kurondedzera kuti zvinotarisirwa chaizvoizvo, zvinokwanisika kunenge kwose chezvinodhaka Russia. Paavhareji mutengo muna Russian Federation mumate anenge 500 rubles. Kubata zvinodhaka nyore huru. A kuwanda vanhu vaigona kubvisa uye zvakaratidzwa pachena kuburikidza ichi chinoreva. Sezvakataurwa kubudikidza Professor Skulachev, Madonhwe ziso, mutengo chiri kuwanikwa wose achava zvinobudirira kuchirapa nezvinozoitika vaya vanotambura nezvirwere ziso.

Hapana mubvunzo kuti pashure imwe nguva, yokutsvakurudza mumayunivhesiti kudzidza zvakazara-pamwero kudzidza ziso anodonhedza "Vizomitin" uye ipapo mukuru mukana pachava nemikana mitsva nokuda kushandisa mitochondrial antioxidants kwete chete munzvimbo kunotoda muitiro ophthalmology, asiwo mune mamwe mapazi emishonga.

Reviews kugadzirira

Zvakawanda uchapupu vanhu vakashandisa ziso anodonhedza "Vizomitin" yakavakirwa zvavo chiito. Varwere vari kufara kuti kugadzirira hakurevi kuti kakawanda instillation, uye kushandiswa kwenguva refu, uye anoita kuti kakawanda kushandiswa kwayo zvingaderedzwa kuti kamwe pazuva. Maererano vatengi, matambudziko ziso here kugadziriswa. Vasisipo ndinotsveruka, zvishoma akaneta, kuzvimba kunoitika. Chero nemishonga, varwere havana kumbozviona.